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The map label for this gene is tas [H]

Identifier: 114798332

GI number: 114798332

Start: 3674624

End: 3675640

Strand: Direct

Name: tas [H]

Synonym: HNE_3540

Alternate gene names: 114798332

Gene position: 3674624-3675640 (Clockwise)

Preceding gene: 114798850

Following gene: 114798374

Centisome position: 99.18

GC content: 58.9

Gene sequence:

>1017_bases
ATGCAACATCGCCGCCTCGGTAAAAGCGCCATCTATGTTTCCGACATCTGCATGGGAACCATGACCTTCGGAACCCAGAC
AGATGAAAAGGAAGCGTTCCGCATTCTCGATGCGAGCCTGGACGCAGGGATCAACTTTTTCGACACGGCCGAGAATTATC
CCGTACCGCCGGACCTAAAATATGGCGGGCTGACAGAGGAAATCTTCGGGCGCTGGATGAAAACCAAGGACCGGGATTCG
ATTATCCTGGCCACCAAAGTGTGCGGGCCTTCGCATGGCTGGATCAAGGGATCGCAGCGGGCGGGCATGACGGCGCTGGA
CCGGCACAATATCCGCCGCGCCGTGGAGGCGAGCCTGACCCGGCTGCAGACGGACTATATCGATCTTTACCAGACCCATT
GGCCTGACCACGGGACCGAGTTCGATGAGACGATGGAAGCCCTCGATGATCTTGTGCGCGAGGGATACGTTCGGATCGTG
GGCTGCTCGAACGAGGACGCCTGGGGCCTGATGAAATCCATTGAGACGTCCAATCGTCTCGGAACGGTCCGTTATCAGAC
GATCCAGAATAACTTCTCGCTCAACAATCGCCGGTTCGAGGACGCGCTGGCGAAGATCTGTGACCGTGAGGGCGTGAGCC
TGATCCCTTATTCCCCTCTGGGCGGCGGCGTGCTGTCGGGCAAGTATCAGAACGGCGCGTTTCCGGAAGGCGCCCGGTTC
TCGGCCTATGCCAACAAGGGCGGACGCCATACGGCGATGGCGCAGCGCTTCGTCAACGAAAAGTCCCTCGCCGCAACGGC
GCGCTATATGGAGATCGCCAAGGAAGCGGGCATGAGCCCGGTGACGCTGGCGACGGCCTGGTCAAAGCAGCACAGCTTTG
TGGCCTCCACGATTGTCGGCGTTTCGAAGTTTGATCAGCTCGAAGAGATTCTGGCCGCAGGCGACCTGGTGCTTTCGGAC
GATGTGATGAAAGCGTGTGAGAAGGTTACGCGGGAAATTCTCTATCCGATGGGGTGA

Upstream 100 bases:

>100_bases
GAAGGCTGCCTTCCGCGGGGAGAACGTGAGGCCCGGTGACTGGCGCTTGGCGCGCGCGGCGTTAGGGTGGGCGCCGATAA
ACTCTAAGGGAGCCAACGCC

Downstream 100 bases:

>100_bases
GAGGTTCGGCAAGCACCTCCGGCCTCCCCTGCCTTGGCGGGGGAGGTAATGAGGCTGTGTTTGAACGCGTTTAAGAGCTG
TTGATCCCGGCCCAGGCCTC

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQHRRLGKSAIYVSDICMGTMTFGTQTDEKEAFRILDASLDAGINFFDTAENYPVPPDLKYGGLTEEIFGRWMKTKDRDS
IILATKVCGPSHGWIKGSQRAGMTALDRHNIRRAVEASLTRLQTDYIDLYQTHWPDHGTEFDETMEALDDLVREGYVRIV
GCSNEDAWGLMKSIETSNRLGTVRYQTIQNNFSLNNRRFEDALAKICDREGVSLIPYSPLGGGVLSGKYQNGAFPEGARF
SAYANKGGRHTAMAQRFVNEKSLAATARYMEIAKEAGMSPVTLATAWSKQHSFVASTIVGVSKFDQLEEILAAGDLVLSD
DVMKACEKVTREILYPMG

Sequences:

>Translated_338_residues
MQHRRLGKSAIYVSDICMGTMTFGTQTDEKEAFRILDASLDAGINFFDTAENYPVPPDLKYGGLTEEIFGRWMKTKDRDS
IILATKVCGPSHGWIKGSQRAGMTALDRHNIRRAVEASLTRLQTDYIDLYQTHWPDHGTEFDETMEALDDLVREGYVRIV
GCSNEDAWGLMKSIETSNRLGTVRYQTIQNNFSLNNRRFEDALAKICDREGVSLIPYSPLGGGVLSGKYQNGAFPEGARF
SAYANKGGRHTAMAQRFVNEKSLAATARYMEIAKEAGMSPVTLATAWSKQHSFVASTIVGVSKFDQLEEILAAGDLVLSD
DVMKACEKVTREILYPMG
>Mature_338_residues
MQHRRLGKSAIYVSDICMGTMTFGTQTDEKEAFRILDASLDAGINFFDTAENYPVPPDLKYGGLTEEIFGRWMKTKDRDS
IILATKVCGPSHGWIKGSQRAGMTALDRHNIRRAVEASLTRLQTDYIDLYQTHWPDHGTEFDETMEALDDLVREGYVRIV
GCSNEDAWGLMKSIETSNRLGTVRYQTIQNNFSLNNRRFEDALAKICDREGVSLIPYSPLGGGVLSGKYQNGAFPEGARF
SAYANKGGRHTAMAQRFVNEKSLAATARYMEIAKEAGMSPVTLATAWSKQHSFVASTIVGVSKFDQLEEILAAGDLVLSD
DVMKACEKVTREILYPMG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=344, Percent_Identity=29.0697674418605, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI27436964, Length=344, Percent_Identity=28.7790697674419, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436962, Length=344, Percent_Identity=28.7790697674419, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI27436969, Length=320, Percent_Identity=29.6875, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=318, Percent_Identity=29.559748427673, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436971, Length=317, Percent_Identity=27.4447949526814, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI223718702, Length=310, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI41327764, Length=224, Percent_Identity=30.3571428571429, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI41152114, Length=225, Percent_Identity=29.7777777777778, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1789199, Length=354, Percent_Identity=41.2429378531073, Blast_Score=254, Evalue=5e-69,
Organism=Escherichia coli, GI87081735, Length=338, Percent_Identity=30.7692307692308, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=29.2682926829268, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=29.940119760479, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788081, Length=234, Percent_Identity=29.4871794871795, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=27.3015873015873, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=338, Percent_Identity=26.6272189349112, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=26.1627906976744, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=334, Percent_Identity=27.2455089820359, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=25.5813953488372, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=198, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=24.5714285714286, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45549126, Length=360, Percent_Identity=24.4444444444444, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24646155, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646159, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37584; Mature: 37584

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHRRLGKSAIYVSDICMGTMTFGTQTDEKEAFRILDASLDAGINFFDTAENYPVPPDLK
CCCCHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
YGGLTEEIFGRWMKTKDRDSIILATKVCGPSHGWIKGSQRAGMTALDRHNIRRAVEASLT
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLQTDYIDLYQTHWPDHGTEFDETMEALDDLVREGYVRIVGCSNEDAWGLMKSIETSNRL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCC
GTVRYQTIQNNFSLNNRRFEDALAKICDREGVSLIPYSPLGGGVLSGKYQNGAFPEGARF
CEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCEECCCCCCCCCCCCCCE
SAYANKGGRHTAMAQRFVNEKSLAATARYMEIAKEAGMSPVTLATAWSKQHSFVASTIVG
EHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
VSKFDQLEEILAAGDLVLSDDVMKACEKVTREILYPMG
HHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQHRRLGKSAIYVSDICMGTMTFGTQTDEKEAFRILDASLDAGINFFDTAENYPVPPDLK
CCCCHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
YGGLTEEIFGRWMKTKDRDSIILATKVCGPSHGWIKGSQRAGMTALDRHNIRRAVEASLT
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLQTDYIDLYQTHWPDHGTEFDETMEALDDLVREGYVRIVGCSNEDAWGLMKSIETSNRL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCC
GTVRYQTIQNNFSLNNRRFEDALAKICDREGVSLIPYSPLGGGVLSGKYQNGAFPEGARF
CEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCEECCCCCCCCCCCCCCE
SAYANKGGRHTAMAQRFVNEKSLAATARYMEIAKEAGMSPVTLATAWSKQHSFVASTIVG
EHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
VSKFDQLEEILAAGDLVLSDDVMKACEKVTREILYPMG
HHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]