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The map label for this gene is oxyR [H]

Identifier: 114798315

GI number: 114798315

Start: 1562342

End: 1563262

Strand: Direct

Name: oxyR [H]

Synonym: HNE_1531

Alternate gene names: 114798315

Gene position: 1562342-1563262 (Clockwise)

Preceding gene: 114797735

Following gene: 114798209

Centisome position: 42.17

GC content: 62.43

Gene sequence:

>921_bases
ATGCGCCCGACCCTTAGACAGATGCAGTATGTCATCGCCATCGCGGATACAGGCAAGTTCGGCGACGCCGCACGGCTGGT
AAATGTCAGCCAGCCAAGCCTGTCGGCCCAGATTGCGGAAATGGAGGCCGGGCTCGGCGTCGCGCTTGTTGAAAGATCCA
GCCGCGGGGCGATGCTGACACCTGCGGGCGAGGAGCTGGTGCGCCGCGCGCGGCTTATCCTCCGGGATGTTGAGGATCTG
AAAGCCGTTGCAAAGCTTGGCCGGACAGAACTTTCCGGCCGCCTGCGGCTGGGCGTCCTGCCCACAATTGGCCCTTACCT
CTTGCCCAAGGCGACCGGAGACCTGCGGGCGCGCTTTCCGGACCTGCGCCTCAGCGTGCGAGAGGAGCGGACCGTTGACC
TCGATGAGCATCTCCAGGCAGGCCTTTTTGACACTGTCCTTTCTACACCGGAAGACCATCCGGGCACTGAATCAGAGCAT
CTGTTTACGGAGCGGCTGTATGCTTGCCCGCCGCCTGGCGATGAGCTTGCAGAAGGTGAGGGGCCTGTCGCGCTCAGTGC
CCTCGAAGGCCGTTCGCTACTGACGCTCGGGGAAGGGCACAGGCTGAGTGCGATCACCCAGGAGCTCGCAAAAGCGGCTG
GCGCCACAGTCAGCTCAGAGTATGAAGGGACGTCTCTGGACGCTATCCGCCTTATGGCGCAAATGGGCGCCGGCATCGCC
ATTCTTCCCAGCCTCTATGCCCTTTCCGAGGCCCGGCGCGATCGCGGTCTCAACATCCGCCCCATCAATGATGCCCGCGC
TTGCCGGGACATTGCTCTCATCTGGCGCGAAACGTCCCCGCTGACGGCAAGCCTCGTGAGCCTGTCCACCTATCTGAAGA
AGGCAGCAGAGAAGATTCTGATAACCGAAACAGGGTCATGA

Upstream 100 bases:

>100_bases
CTTTTTAGCAAGCCGGTGATCGGCTTGAGCAGGAGATGGGGCTTGAACCTGAATAGCTCCAATCTAACTATTCTCTCAAA
TCAATAGGAATAAGCTATCG

Downstream 100 bases:

>100_bases
CCAGCCAGGCAGATAGTTGAACACCGGCGGCCTATCAGGGCGCGTGGTCCGCACACCGAGTACATCGGCGGTGATTGGCC
CGCTATTAGCGGTAGCCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRPTLRQMQYVIAIADTGKFGDAARLVNVSQPSLSAQIAEMEAGLGVALVERSSRGAMLTPAGEELVRRARLILRDVEDL
KAVAKLGRTELSGRLRLGVLPTIGPYLLPKATGDLRARFPDLRLSVREERTVDLDEHLQAGLFDTVLSTPEDHPGTESEH
LFTERLYACPPPGDELAEGEGPVALSALEGRSLLTLGEGHRLSAITQELAKAAGATVSSEYEGTSLDAIRLMAQMGAGIA
ILPSLYALSEARRDRGLNIRPINDARACRDIALIWRETSPLTASLVSLSTYLKKAAEKILITETGS

Sequences:

>Translated_306_residues
MRPTLRQMQYVIAIADTGKFGDAARLVNVSQPSLSAQIAEMEAGLGVALVERSSRGAMLTPAGEELVRRARLILRDVEDL
KAVAKLGRTELSGRLRLGVLPTIGPYLLPKATGDLRARFPDLRLSVREERTVDLDEHLQAGLFDTVLSTPEDHPGTESEH
LFTERLYACPPPGDELAEGEGPVALSALEGRSLLTLGEGHRLSAITQELAKAAGATVSSEYEGTSLDAIRLMAQMGAGIA
ILPSLYALSEARRDRGLNIRPINDARACRDIALIWRETSPLTASLVSLSTYLKKAAEKILITETGS
>Mature_306_residues
MRPTLRQMQYVIAIADTGKFGDAARLVNVSQPSLSAQIAEMEAGLGVALVERSSRGAMLTPAGEELVRRARLILRDVEDL
KAVAKLGRTELSGRLRLGVLPTIGPYLLPKATGDLRARFPDLRLSVREERTVDLDEHLQAGLFDTVLSTPEDHPGTESEH
LFTERLYACPPPGDELAEGEGPVALSALEGRSLLTLGEGHRLSAITQELAKAAGATVSSEYEGTSLDAIRLMAQMGAGIA
ILPSLYALSEARRDRGLNIRPINDARACRDIALIWRETSPLTASLVSLSTYLKKAAEKILITETGS

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=36.2007168458781, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=31.4410480349345, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693105, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=28.6549707602339, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787879, Length=307, Percent_Identity=28.6644951140065, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI2367136, Length=299, Percent_Identity=27.0903010033445, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=29.0983606557377, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788297, Length=176, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=24.5059288537549, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693193, Length=152, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789204, Length=300, Percent_Identity=24.3333333333333, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=26.1044176706827, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081904, Length=182, Percent_Identity=31.3186813186813, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787806, Length=286, Percent_Identity=23.4265734265734, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32973; Mature: 32973

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTLRQMQYVIAIADTGKFGDAARLVNVSQPSLSAQIAEMEAGLGVALVERSSRGAMLT
CCCHHHHHEEEEEEECCCCCCCHHHEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEC
PAGEELVRRARLILRDVEDLKAVAKLGRTELSGRLRLGVLPTIGPYLLPKATGDLRARFP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEECCCCCCHHCCCCCCHHHHCCC
DLRLSVREERTVDLDEHLQAGLFDTVLSTPEDHPGTESEHLFTERLYACPPPGDELAEGE
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCC
GPVALSALEGRSLLTLGEGHRLSAITQELAKAAGATVSSEYEGTSLDAIRLMAQMGAGIA
CCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEE
ILPSLYALSEARRDRGLNIRPINDARACRDIALIWRETSPLTASLVSLSTYLKKAAEKIL
HHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHEEE
ITETGS
EEECCC
>Mature Secondary Structure
MRPTLRQMQYVIAIADTGKFGDAARLVNVSQPSLSAQIAEMEAGLGVALVERSSRGAMLT
CCCHHHHHEEEEEEECCCCCCCHHHEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEC
PAGEELVRRARLILRDVEDLKAVAKLGRTELSGRLRLGVLPTIGPYLLPKATGDLRARFP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEECCCCCCHHCCCCCCHHHHCCC
DLRLSVREERTVDLDEHLQAGLFDTVLSTPEDHPGTESEHLFTERLYACPPPGDELAEGE
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCC
GPVALSALEGRSLLTLGEGHRLSAITQELAKAAGATVSSEYEGTSLDAIRLMAQMGAGIA
CCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEE
ILPSLYALSEARRDRGLNIRPINDARACRDIALIWRETSPLTASLVSLSTYLKKAAEKIL
HHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHEEE
ITETGS
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]