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The map label for this gene is rpoC

Identifier: 114798314

GI number: 114798314

Start: 3009131

End: 3013339

Strand: Reverse

Name: rpoC

Synonym: HNE_2857

Alternate gene names: 114798314

Gene position: 3013339-3009131 (Counterclockwise)

Preceding gene: 114799111

Following gene: 114800161

Centisome position: 81.33

GC content: 61.75

Gene sequence:

>4209_bases
ATGCGCCAGGACGTCGCCAACATGTTCAACCAGAATGCGCCCGCCCCGAGTTTCGAGGCGATCCGCATTTCGATTGCGAG
CCCGGAGAAAATCCGCTCGTGGTCGTCGGGTGAAATCAAGAAGCCTGAAACCATCAACTACCGGACGTTCAAACCGGAGC
GCGACGGCCTATTCTGTGCGCGGATCTTCGGCCCGACGAAGGACTATGAGTGCCTCTGCGGAAAGTACAAGCGCATCAAG
TATCGCGGCATCGTCTGCGAGAAATGCGGCGTTGAAGTCACGCTCGCCCGCGTTCGCCGCGAGCGGATGGGTCACATCGA
CCTGGCCGCGCCGGTTGCGCACATCTGGTTCCTGAAGTCGCTGCCGTCCCGGATCTCGACGCTGGTCGACATGCCGCTCA
AGGATGTTGAGCGCGTGCTTTATTTCGAGAGCTATGTCGTCATCGAGCCCGGCCTGACCGAGCTTGAGCCACTGCAGCTG
CTGACCGAAGAAGAGTATATGGACGCGCAGGATCGCCTCGGCGAAGACGCGTTCACCGCTCTGATCGGCGCCGAAGCCAT
CCGCGAAATCCTCAAGAGCCTCGACCTGCCGACGCTGGCCGAGACGCTTCGCGAGGAACTGCGTGAGTCGAGCTCTGAAC
TGAAGACGAAGAAGTATTCCAAGCGCCTTAAGGTGGTGGACTCCTTCATTCAGTCGAAAGCCAAGCCGGAATGGATGATC
CTCACGGTTGTCCCGGTCATCCCGCCCGACCTGCGCCCGCTGGTCCCGCTGGATGGCGGCCGCTTTGCGACCTCTGACCT
TAACGACCTCTATCGCCGCGTGATCAACCGGAACAACCGCCTGAAGCGCCTGATGGAGCTTCGCGCGCCGGACATCATCA
TCCGCAACGAGAAGCGGATGCTTCAGGAGTCGGTTGACGCCCTGTTCGACAACGGCCGCCGTGGCCGCACGATCACCGGC
ACCAACAAGCGCCCGCTGAAGTCGATCTCCGACATGCTCAAGGGCAAGCAGGGCCGCTTCCGCCAGAACCTTCTGGGCAA
GCGCGTCGACTATTCTGGCCGTTCGGTCATCGTGGTCGGCCCGAACCTCAAGCTGCACGAGTGCGGCCTGCCCAAGAAAA
TGGCGCTCGAGCTGTTCAAGCCGTTCATCTATGCGCGCCTCGATGCCAAAGGCCTCGCCGGCACGGTGAAAGCGGCCAAG
AAGCTCGTGGAAAAAGAAAAGCCCGAAGTGTGGGACATCCTCGATGAGGTGATCCGCGAGCACCCGGTTCTTCTCAACCG
CGCGCCGACGCTCCACCGTCTGGGCATCCAGGCGTTCGAGCCCAAACTGATTGAAGGCAAGGCCATCCAGCTGCACCCGC
TCGTCTGCGCTGCATTCAACGCAGACTTCGACGGCGACCAGATGGCGGTCCACGTTCCACTGAGCCTCGAGGCCCAGCTG
GAATGCCGCGTGCTGATGATGTCGACCAACAACATCCTCTCGCCCGCCAACGGCAAGCCAATCATCGTTCCGTCCCAGGA
CATCATCCTCGGTCTCTATTACCTCTCGCTCGACCGTAAGGGCGAGATCGGTGAGGGCATGGTCTTTGCTGACCTTGCCG
AGATCGAGCATGCGCTGGATGCGGGCCTCGTCTCGCTCCACTCCAAGGTCCGCGCGCTCTATGACGGCGTCGATTCGGAC
GGCAAGCCTGAGCGCCGCATCATTGATACGACGCCAGGCCGCTACATGGTGGCGAACATCCTGCCGCGCTCGAAGGCGAT
TGGACCTGAACTGGTCAACACCGTTCTTTCCAAGAAAGCGATCGGCAAGATCATCGACGAAGTCTACCGCCTGTGTGGTC
AGAAGGCGACGGTGATCTTCTGTGACAAGATGATGGAGCTCGGCTTCCGCGAAGCCTGCAAGGCCGGCATCTCCTTCGGC
AAGGATGACATGGTCATCCCGGAAGCGAAGAAGCGTCTGGTCGACGCGACCAAGGATCTCGTCTCCGATTACGAGCGTCA
GTATGCTGACGGTCTGATCACGCGCGGCGAGAAGTACAACAAGGTCGTCGATGCCTGGTCCAGCTGCACCGACAAGGTCG
CTGACGCCATGATGGAGTCGGCTGCCAAGATGCAGGTGTCGCGCGGCAAGGAGCAGGTCAACTCGATCTTCATGATGGCC
GACTCCGGGGCGCGTGGTTCGAAGAACCAGATGAAGCAGCTCGCCGGTATGCGCGGCCTCATGGCCAAGCCATCGGGCGA
GATCATCGAGACGCCGATCATCTCGAACTTCAAGGAAGGTCTGACCGTTCTTGAATACTTCAACTCGACCCACGGCGCCC
GTAAGGGGCTGGCCGATACGGCTCTGAAGACCGCCAACTCCGGTTACCTCACACGCCGCCTCGTTGACGTGGCGCAGGAC
TGCATCATCAACGAAGATGATTGCGGTACGGAGAAGGGCATCGACATCAACGCCGTCATGGAAGGCGCCGACGTTGTGGT
GTCGCTCAATGAGCGCATCCTCGGCCGCGTCATCGCCGAAGACATCAAGGGGCCAGACGGCAAGCTCGTCGTTCCGGCCA
ATACCTATGTCGACGAAGACGTTGCAGCGCTGATCGACACGGCAACGGTGGACCGCGTGAAAGTGCGTTCGCCGCTGACC
TGCGAAACCAAGAACGGCATCTGTGCCCAGTGCTACGGCCGCGACCTGGCTCGCGGTACTCTGGTCAACCGCGGTGAGGC
TGTCGGCGTTATCGCTGCTCAGTCGATCGGGGAGCCGGGTACCCAGCTCACCATGCGTACCTTCCACATCGGCGGCGCCG
CTCAGGTGGCGGACCAATCCTCGCTCGAAGCCAGCTTCGAAGGCACCGTGCGGTTCACCGATGCCGAGATCGTTACCCGC
AAGGACAAGACGATCGTGGTCGTTGGCCGCCGCATGCAGGTCGAAATCGTCGATGCCGACGGGCGTACCCGTCAGTCGTT
CCGCCCCGCCTACGGCACGCGCCTGATGGCCAAGGACGGCGACAAGGTCATGCCGGGCAAACTGCTCGCTGACTGGGACC
CCTTTGCCCAGCCGATCGTCTCGGAAGTTGCCGGTGAAGCTCGCTTCATCGACCTCTCTGAAGGCACAACGGTGCGGGAA
GAAACCGACGAAGCGACCGGTATCTCGGCCCGTGTGGTTGTTGACCCCCGGTCGACCTCCAAAACCGCCGACCTCAAGCC
GTCGATCCAGATCGTTGACGCCAGCGGCAAGCCCGTGAAGCTGCCTAACGGTTCGCCGGCGACCTATGTTCTCTCCGTTG
GCGCGATCCTGTCGGTCTCCGACGGTGACCGGATCGAGCCGGGTGACACGCTCTCGCGCGTCGCAACGGGCGGTGCCAAG
ACGAAAGACATCACGGGCGGTCTGCCGCGCGTGGCTGAACTCTTCGAAGCCCGGCGTCCGAAGGACCATGCGATCATCGC
GGAAGTCGATGGCCGCGTCGAATACGGCCGCGACTACAAGAACAAGCGCAAGGTCACGATCGTGCCGACAGAAGAGGGGC
GTGAGCCCATCGACTATCTGGTGCCGAAAGGGAAACACCTTGCGGTTCAGGATGGCGACTTCATCAAGCGCGGTGAGTAT
CTGATGGACGGTAACCCCGCCCCGCAGGACATCCTCTCGACGCTCGGCGTGGAAGCCCTGGCCAACTATCTCACGGACGA
AGTGCAGAAGGTCTATCGCCTGCAAGGCGTGCCGATCAACGACAAGCACATCGAAGTGATCGTTCGCCAGATGCTGCAGA
AGGTCGAGATCACCGATGGTGGCGATACGGTGTTCATCACCGGCGAGCACATCGATGCGATCGAGTTCGATGAAGCCAAC
GAGGCGATCCGCAAGTCGCGCAAGAAAGACCAGCGCGAAGCAACGGCTAACCCGCTGCTGCTCGGTATCACCAAGGCCTC
GCTCCAGACGCGCAGCTTCATCTCGGCTGCCTCGTTCCAGGAAACGACCCGCGTGCTCACCGAAGCGGCCATCCAGGGCA
AGATCGACACGCTCGACGGTCTCAAGGAGAACGTCATCGTGGGCCGTCTCATCCCGGCCGGTACGGGCGGCGGTATCCGC
CAGTTCCGCCGCGTGGCTGCCGAGCGCGATCTGAAGCTCAAGGCGAAGCGCGCAGCGGCCATGGCCAAGGCGGAGGAGGG
GATCAACCTCGTCAGCCTCCCGGCCCCTGAGCGCGACACAGCCGAATAA

Upstream 100 bases:

>100_bases
TTAGGCCCCGCTGATGAGGCGGGGCCACGCCGACCCGATTTTTTCAGGGCAGGGGAGCCAGATCTCCCTTCAAATGCCCG
CCCCAAGGAGCAGACACCCT

Downstream 100 bases:

>100_bases
GCCGGCATGACTTGAAACAACCGGAAAAGCCTGCCAGCAATGGCAGGCTTTTTCACGTTTCGGGCGCACATTCATGAAGG
CAGGACGGACACAGATCGCA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1402; Mature: 1402

Protein sequence:

>1402_residues
MRQDVANMFNQNAPAPSFEAIRISIASPEKIRSWSSGEIKKPETINYRTFKPERDGLFCARIFGPTKDYECLCGKYKRIK
YRGIVCEKCGVEVTLARVRRERMGHIDLAAPVAHIWFLKSLPSRISTLVDMPLKDVERVLYFESYVVIEPGLTELEPLQL
LTEEEYMDAQDRLGEDAFTALIGAEAIREILKSLDLPTLAETLREELRESSSELKTKKYSKRLKVVDSFIQSKAKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQESVDALFDNGRRGRTITG
TNKRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHECGLPKKMALELFKPFIYARLDAKGLAGTVKAAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
ECRVLMMSTNNILSPANGKPIIVPSQDIILGLYYLSLDRKGEIGEGMVFADLAEIEHALDAGLVSLHSKVRALYDGVDSD
GKPERRIIDTTPGRYMVANILPRSKAIGPELVNTVLSKKAIGKIIDEVYRLCGQKATVIFCDKMMELGFREACKAGISFG
KDDMVIPEAKKRLVDATKDLVSDYERQYADGLITRGEKYNKVVDAWSSCTDKVADAMMESAAKMQVSRGKEQVNSIFMMA
DSGARGSKNQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQD
CIINEDDCGTEKGIDINAVMEGADVVVSLNERILGRVIAEDIKGPDGKLVVPANTYVDEDVAALIDTATVDRVKVRSPLT
CETKNGICAQCYGRDLARGTLVNRGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVADQSSLEASFEGTVRFTDAEIVTR
KDKTIVVVGRRMQVEIVDADGRTRQSFRPAYGTRLMAKDGDKVMPGKLLADWDPFAQPIVSEVAGEARFIDLSEGTTVRE
ETDEATGISARVVVDPRSTSKTADLKPSIQIVDASGKPVKLPNGSPATYVLSVGAILSVSDGDRIEPGDTLSRVATGGAK
TKDITGGLPRVAELFEARRPKDHAIIAEVDGRVEYGRDYKNKRKVTIVPTEEGREPIDYLVPKGKHLAVQDGDFIKRGEY
LMDGNPAPQDILSTLGVEALANYLTDEVQKVYRLQGVPINDKHIEVIVRQMLQKVEITDGGDTVFITGEHIDAIEFDEAN
EAIRKSRKKDQREATANPLLLGITKASLQTRSFISAASFQETTRVLTEAAIQGKIDTLDGLKENVIVGRLIPAGTGGGIR
QFRRVAAERDLKLKAKRAAAMAKAEEGINLVSLPAPERDTAE

Sequences:

>Translated_1402_residues
MRQDVANMFNQNAPAPSFEAIRISIASPEKIRSWSSGEIKKPETINYRTFKPERDGLFCARIFGPTKDYECLCGKYKRIK
YRGIVCEKCGVEVTLARVRRERMGHIDLAAPVAHIWFLKSLPSRISTLVDMPLKDVERVLYFESYVVIEPGLTELEPLQL
LTEEEYMDAQDRLGEDAFTALIGAEAIREILKSLDLPTLAETLREELRESSSELKTKKYSKRLKVVDSFIQSKAKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQESVDALFDNGRRGRTITG
TNKRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHECGLPKKMALELFKPFIYARLDAKGLAGTVKAAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
ECRVLMMSTNNILSPANGKPIIVPSQDIILGLYYLSLDRKGEIGEGMVFADLAEIEHALDAGLVSLHSKVRALYDGVDSD
GKPERRIIDTTPGRYMVANILPRSKAIGPELVNTVLSKKAIGKIIDEVYRLCGQKATVIFCDKMMELGFREACKAGISFG
KDDMVIPEAKKRLVDATKDLVSDYERQYADGLITRGEKYNKVVDAWSSCTDKVADAMMESAAKMQVSRGKEQVNSIFMMA
DSGARGSKNQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQD
CIINEDDCGTEKGIDINAVMEGADVVVSLNERILGRVIAEDIKGPDGKLVVPANTYVDEDVAALIDTATVDRVKVRSPLT
CETKNGICAQCYGRDLARGTLVNRGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVADQSSLEASFEGTVRFTDAEIVTR
KDKTIVVVGRRMQVEIVDADGRTRQSFRPAYGTRLMAKDGDKVMPGKLLADWDPFAQPIVSEVAGEARFIDLSEGTTVRE
ETDEATGISARVVVDPRSTSKTADLKPSIQIVDASGKPVKLPNGSPATYVLSVGAILSVSDGDRIEPGDTLSRVATGGAK
TKDITGGLPRVAELFEARRPKDHAIIAEVDGRVEYGRDYKNKRKVTIVPTEEGREPIDYLVPKGKHLAVQDGDFIKRGEY
LMDGNPAPQDILSTLGVEALANYLTDEVQKVYRLQGVPINDKHIEVIVRQMLQKVEITDGGDTVFITGEHIDAIEFDEAN
EAIRKSRKKDQREATANPLLLGITKASLQTRSFISAASFQETTRVLTEAAIQGKIDTLDGLKENVIVGRLIPAGTGGGIR
QFRRVAAERDLKLKAKRAAAMAKAEEGINLVSLPAPERDTAE
>Mature_1402_residues
MRQDVANMFNQNAPAPSFEAIRISIASPEKIRSWSSGEIKKPETINYRTFKPERDGLFCARIFGPTKDYECLCGKYKRIK
YRGIVCEKCGVEVTLARVRRERMGHIDLAAPVAHIWFLKSLPSRISTLVDMPLKDVERVLYFESYVVIEPGLTELEPLQL
LTEEEYMDAQDRLGEDAFTALIGAEAIREILKSLDLPTLAETLREELRESSSELKTKKYSKRLKVVDSFIQSKAKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQESVDALFDNGRRGRTITG
TNKRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHECGLPKKMALELFKPFIYARLDAKGLAGTVKAAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
ECRVLMMSTNNILSPANGKPIIVPSQDIILGLYYLSLDRKGEIGEGMVFADLAEIEHALDAGLVSLHSKVRALYDGVDSD
GKPERRIIDTTPGRYMVANILPRSKAIGPELVNTVLSKKAIGKIIDEVYRLCGQKATVIFCDKMMELGFREACKAGISFG
KDDMVIPEAKKRLVDATKDLVSDYERQYADGLITRGEKYNKVVDAWSSCTDKVADAMMESAAKMQVSRGKEQVNSIFMMA
DSGARGSKNQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQD
CIINEDDCGTEKGIDINAVMEGADVVVSLNERILGRVIAEDIKGPDGKLVVPANTYVDEDVAALIDTATVDRVKVRSPLT
CETKNGICAQCYGRDLARGTLVNRGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVADQSSLEASFEGTVRFTDAEIVTR
KDKTIVVVGRRMQVEIVDADGRTRQSFRPAYGTRLMAKDGDKVMPGKLLADWDPFAQPIVSEVAGEARFIDLSEGTTVRE
ETDEATGISARVVVDPRSTSKTADLKPSIQIVDASGKPVKLPNGSPATYVLSVGAILSVSDGDRIEPGDTLSRVATGGAK
TKDITGGLPRVAELFEARRPKDHAIIAEVDGRVEYGRDYKNKRKVTIVPTEEGREPIDYLVPKGKHLAVQDGDFIKRGEY
LMDGNPAPQDILSTLGVEALANYLTDEVQKVYRLQGVPINDKHIEVIVRQMLQKVEITDGGDTVFITGEHIDAIEFDEAN
EAIRKSRKKDQREATANPLLLGITKASLQTRSFISAASFQETTRVLTEAAIQGKIDTLDGLKENVIVGRLIPAGTGGGIR
QFRRVAAERDLKLKAKRAAAMAKAEEGINLVSLPAPERDTAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=661, Percent_Identity=26.6263237518911, Blast_Score=183, Evalue=1e-45,
Organism=Homo sapiens, GI39725938, Length=678, Percent_Identity=25.811209439528, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI103471997, Length=624, Percent_Identity=24.0384615384615, Blast_Score=114, Evalue=5e-25,
Organism=Escherichia coli, GI2367335, Length=1383, Percent_Identity=60.4483007953724, Blast_Score=1670, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=653, Percent_Identity=27.2588055130168, Blast_Score=181, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI25145495, Length=663, Percent_Identity=26.8476621417798, Blast_Score=171, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320061, Length=903, Percent_Identity=25.2491694352159, Blast_Score=196, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324690, Length=595, Percent_Identity=26.218487394958, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI17530899, Length=912, Percent_Identity=24.5614035087719, Blast_Score=179, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281360912, Length=887, Percent_Identity=26.2683201803833, Blast_Score=172, Evalue=2e-42,
Organism=Drosophila melanogaster, GI17647875, Length=432, Percent_Identity=25.6944444444444, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_HYPNA (Q0BYA8)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761535.1
- ProteinModelPortal:   Q0BYA8
- STRING:   Q0BYA8
- GeneID:   4289478
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2857
- NMPDR:   fig|228405.5.peg.2738
- TIGR:   HNE_2857
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q0BYA8
- ProtClustDB:   PRK00566
- BioCyc:   HNEP81032:HNE_2857-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 154546; Mature: 154546

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDVANMFNQNAPAPSFEAIRISIASPEKIRSWSSGEIKKPETINYRTFKPERDGLFCA
CCCHHHHHHCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPTKDYECLCGKYKRIKYRGIVCEKCGVEVTLARVRRERMGHIDLAAPVAHIWFLKS
EECCCCCCHHHHHCHHHEEEECCEEEHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LPSRISTLVDMPLKDVERVLYFESYVVIEPGLTELEPLQLLTEEEYMDAQDRLGEDAFTA
HHHHHHHHHCCCHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHH
LIGAEAIREILKSLDLPTLAETLREELRESSSELKTKKYSKRLKVVDSFIQSKAKPEWMI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDALFDNGRRGRTITGTNKRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PNLKLHECGLPKKMALELFKPFIYARLDAKGLAGTVKAAKKLVEKEKPEVWDILDEVIRE
CCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCCEECCCEEEEECEEEEEECCCCCCCCEEEEECCEECCCE
ECRVLMMSTNNILSPANGKPIIVPSQDIILGLYYLSLDRKGEIGEGMVFADLAEIEHALD
EEEEEEEECCCEECCCCCCEEEECCHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
AGLVSLHSKVRALYDGVDSDGKPERRIIDTTPGRYMVANILPRSKAIGPELVNTVLSKKA
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
IGKIIDEVYRLCGQKATVIFCDKMMELGFREACKAGISFGKDDMVIPEAKKRLVDATKDL
HHHHHHHHHHHHCCCCEEEEHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VSDYERQYADGLITRGEKYNKVVDAWSSCTDKVADAMMESAAKMQVSRGKEQVNSIFMMA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEEEE
DSGARGSKNQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADT
CCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHCCHHHH
ALKTANSGYLTRRLVDVAQDCIINEDDCGTEKGIDINAVMEGADVVVSLNERILGRVIAE
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEECCCCEEEEHHHHHHHHHHHH
DIKGPDGKLVVPANTYVDEDVAALIDTATVDRVKVRSPLTCETKNGICAQCYGRDLARGT
HCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEECCCCCEEECCCCCCHHHHCCHHHCCH
LVNRGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVADQSSLEASFEGTVRFTDAEIVTR
HCCCCCEEEEEEHHCCCCCCCEEEEEEEECCCHHHHCCCHHCCCCCCCEEEEECCEEEEE
KDKTIVVVGRRMQVEIVDADGRTRQSFRPAYGTRLMAKDGDKVMPGKLLADWDPFAQPIV
CCCEEEEECCEEEEEEECCCCCCHHHCCCHHCCEEEECCCCCCCCCCCCCCCCHHHHHHH
SEVAGEARFIDLSEGTTVREETDEATGISARVVVDPRSTSKTADLKPSIQIVDASGKPVK
HHHCCCEEEEECCCCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
LPNGSPATYVLSVGAILSVSDGDRIEPGDTLSRVATGGAKTKDITGGLPRVAELFEARRP
CCCCCCCEEEEEECEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCC
KDHAIIAEVDGRVEYGRDYKNKRKVTIVPTEEGREPIDYLVPKGKHLAVQDGDFIKRGEY
CCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCCEEEEECCCHHHCCCE
LMDGNPAPQDILSTLGVEALANYLTDEVQKVYRLQGVPINDKHIEVIVRQMLQKVEITDG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEECCC
GDTVFITGEHIDAIEFDEANEAIRKSRKKDQREATANPLLLGITKASLQTRSFISAASFQ
CCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHH
ETTRVLTEAAIQGKIDTLDGLKENVIVGRLIPAGTGGGIRQFRRVAAERDLKLKAKRAAA
HHHHHHHHHHHCCCCHHHHCCHHCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHH
MAKAEEGINLVSLPAPERDTAE
HHHHHCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MRQDVANMFNQNAPAPSFEAIRISIASPEKIRSWSSGEIKKPETINYRTFKPERDGLFCA
CCCHHHHHHCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPTKDYECLCGKYKRIKYRGIVCEKCGVEVTLARVRRERMGHIDLAAPVAHIWFLKS
EECCCCCCHHHHHCHHHEEEECCEEEHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LPSRISTLVDMPLKDVERVLYFESYVVIEPGLTELEPLQLLTEEEYMDAQDRLGEDAFTA
HHHHHHHHHCCCHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHH
LIGAEAIREILKSLDLPTLAETLREELRESSSELKTKKYSKRLKVVDSFIQSKAKPEWMI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDALFDNGRRGRTITGTNKRPLKSISDMLKGKQGRFRQNLLGKRVDYSGRSVIVVG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PNLKLHECGLPKKMALELFKPFIYARLDAKGLAGTVKAAKKLVEKEKPEVWDILDEVIRE
CCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCCEECCCEEEEECEEEEEECCCCCCCCEEEEECCEECCCE
ECRVLMMSTNNILSPANGKPIIVPSQDIILGLYYLSLDRKGEIGEGMVFADLAEIEHALD
EEEEEEEECCCEECCCCCCEEEECCHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
AGLVSLHSKVRALYDGVDSDGKPERRIIDTTPGRYMVANILPRSKAIGPELVNTVLSKKA
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
IGKIIDEVYRLCGQKATVIFCDKMMELGFREACKAGISFGKDDMVIPEAKKRLVDATKDL
HHHHHHHHHHHHCCCCEEEEHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VSDYERQYADGLITRGEKYNKVVDAWSSCTDKVADAMMESAAKMQVSRGKEQVNSIFMMA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEEEE
DSGARGSKNQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADT
CCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHCCHHHH
ALKTANSGYLTRRLVDVAQDCIINEDDCGTEKGIDINAVMEGADVVVSLNERILGRVIAE
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEECCCCEEEEHHHHHHHHHHHH
DIKGPDGKLVVPANTYVDEDVAALIDTATVDRVKVRSPLTCETKNGICAQCYGRDLARGT
HCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEECCCCCEEECCCCCCHHHHCCHHHCCH
LVNRGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVADQSSLEASFEGTVRFTDAEIVTR
HCCCCCEEEEEEHHCCCCCCCEEEEEEEECCCHHHHCCCHHCCCCCCCEEEEECCEEEEE
KDKTIVVVGRRMQVEIVDADGRTRQSFRPAYGTRLMAKDGDKVMPGKLLADWDPFAQPIV
CCCEEEEECCEEEEEEECCCCCCHHHCCCHHCCEEEECCCCCCCCCCCCCCCCHHHHHHH
SEVAGEARFIDLSEGTTVREETDEATGISARVVVDPRSTSKTADLKPSIQIVDASGKPVK
HHHCCCEEEEECCCCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
LPNGSPATYVLSVGAILSVSDGDRIEPGDTLSRVATGGAKTKDITGGLPRVAELFEARRP
CCCCCCCEEEEEECEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCC
KDHAIIAEVDGRVEYGRDYKNKRKVTIVPTEEGREPIDYLVPKGKHLAVQDGDFIKRGEY
CCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCCEEEEECCCHHHCCCE
LMDGNPAPQDILSTLGVEALANYLTDEVQKVYRLQGVPINDKHIEVIVRQMLQKVEITDG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEECCC
GDTVFITGEHIDAIEFDEANEAIRKSRKKDQREATANPLLLGITKASLQTRSFISAASFQ
CCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHH
ETTRVLTEAAIQGKIDTLDGLKENVIVGRLIPAGTGGGIRQFRRVAAERDLKLKAKRAAA
HHHHHHHHHHHCCCCHHHHCCHHCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHH
MAKAEEGINLVSLPAPERDTAE
HHHHHCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA