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The map label for this gene is paaG [H]

Identifier: 114798301

GI number: 114798301

Start: 2967465

End: 2968265

Strand: Direct

Name: paaG [H]

Synonym: HNE_2804

Alternate gene names: 114798301

Gene position: 2967465-2968265 (Clockwise)

Preceding gene: 114797083

Following gene: 114800167

Centisome position: 80.09

GC content: 64.92

Gene sequence:

>801_bases
ATGGCGACGTACGAGAAGATTTCCTATGAGCGCAATGGCGACACCGCGATCATCGCCTTCAACGATGACAAGACGCTGAA
TGCCTGTGGCGTCGATACCGCCATCGAGCTGCTCCACGCCTTTGAAGTGGCCGCCAGTGAAGCGCGCTGCACGATCTTCA
CTGGCAAAGGCCGCGGCTTCTGCTCGGGCGCCAATCTCGGCGGCATGGGCTCTGGCCCGGAAATCGCCTATCCCGGCTCC
AAGCCTGATGCCGGCAAGGCGCTGGATGCTTTCTACAATCCCCTCGTCACCGCCATCCGCGAACATCCCCACCCGGTCAT
CACCGCCGTCAACGGCGCCGCTGCCGGTGTCGGCTGCGCGCTCGGCCTGATGGGCGACCTCGTGATCGCCGGCAAAAGCG
CCTACTTCCTCCAAGCCTTCCGCCGCATCGGCCTTGTGCCCGATGGTGGCTCGACCTGGCTGCTCGCCCGCACCATCGGC
CGCGTCCGCGCCATGGAAATGGCTCTCCTCGGCGAAAAGGTTTCCGCCGACCAGGCGCTCGACTGGGGCCTCGTCAACCG
CGTGGTGGATGACGCCGAACTGCTGCCGACCGCTCTGGAATTTGCCCAGAAACTCGCCTCCGGCCCGACGGTCGCCCTGG
CGCTCACGCGCAAGATCATCTGGGACGCGAGCGAATCCGATTTCGGTTCTGCCCTGCACGGCGAGCGCGTCGCCCAGCGC
ACGGCAGGCCGCACGGACGACTTCAAAGAAGGCGTCAGCGCCTTCCTTCAGAAGCGCAAGGCCGAGTTCAAAGGCAAGTA
A

Upstream 100 bases:

>100_bases
AGGCGCCGCAAAGCGCTTACCCGGCGTGAGGCGTTCCCGCCCGCGCTGCTTCGCTCTACAAGCAGGCCAGTAAGATCAGA
ACCATATGAGGGAGACGCCA

Downstream 100 bases:

>100_bases
CCTTCGATTGCCTTATTTTCTTGAGGTTCACCTTAAGGATTATTCAATATTGTCTCCATAGGGTTCTCAAAAGAGAGCCT
TATGGGGACGAGATTTAGAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MATYEKISYERNGDTAIIAFNDDKTLNACGVDTAIELLHAFEVAASEARCTIFTGKGRGFCSGANLGGMGSGPEIAYPGS
KPDAGKALDAFYNPLVTAIREHPHPVITAVNGAAAGVGCALGLMGDLVIAGKSAYFLQAFRRIGLVPDGGSTWLLARTIG
RVRAMEMALLGEKVSADQALDWGLVNRVVDDAELLPTALEFAQKLASGPTVALALTRKIIWDASESDFGSALHGERVAQR
TAGRTDDFKEGVSAFLQKRKAEFKGK

Sequences:

>Translated_266_residues
MATYEKISYERNGDTAIIAFNDDKTLNACGVDTAIELLHAFEVAASEARCTIFTGKGRGFCSGANLGGMGSGPEIAYPGS
KPDAGKALDAFYNPLVTAIREHPHPVITAVNGAAAGVGCALGLMGDLVIAGKSAYFLQAFRRIGLVPDGGSTWLLARTIG
RVRAMEMALLGEKVSADQALDWGLVNRVVDDAELLPTALEFAQKLASGPTVALALTRKIIWDASESDFGSALHGERVAQR
TAGRTDDFKEGVSAFLQKRKAEFKGK
>Mature_265_residues
ATYEKISYERNGDTAIIAFNDDKTLNACGVDTAIELLHAFEVAASEARCTIFTGKGRGFCSGANLGGMGSGPEIAYPGSK
PDAGKALDAFYNPLVTAIREHPHPVITAVNGAAAGVGCALGLMGDLVIAGKSAYFLQAFRRIGLVPDGGSTWLLARTIGR
VRAMEMALLGEKVSADQALDWGLVNRVVDDAELLPTALEFAQKLASGPTVALALTRKIIWDASESDFGSALHGERVAQRT
AGRTDDFKEGVSAFLQKRKAEFKGK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=272, Percent_Identity=31.6176470588235, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI31542718, Length=162, Percent_Identity=35.8024691358025, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI45643119, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI260275230, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI260274832, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4757966, Length=189, Percent_Identity=26.4550264550265, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI51538581, Length=189, Percent_Identity=26.4550264550265, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI25453481, Length=189, Percent_Identity=26.4550264550265, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI51538573, Length=189, Percent_Identity=26.4550264550265, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4757968, Length=220, Percent_Identity=24.5454545454545, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI49355787, Length=220, Percent_Identity=24.5454545454545, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221136756, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI221136753, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI221307494, Length=217, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI70995211, Length=236, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787660, Length=218, Percent_Identity=49.5412844036697, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=32.1969696969697, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI221142681, Length=268, Percent_Identity=31.7164179104478, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788597, Length=275, Percent_Identity=30.5454545454545, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082183, Length=268, Percent_Identity=24.6268656716418, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=268, Percent_Identity=32.089552238806, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17560910, Length=269, Percent_Identity=29.7397769516729, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17535521, Length=261, Percent_Identity=27.2030651340996, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=261, Percent_Identity=29.8850574712644, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540306, Length=256, Percent_Identity=28.125, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=22.9571984435798, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129971, Length=265, Percent_Identity=30.5660377358491, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24653477, Length=265, Percent_Identity=30.5660377358491, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24654903, Length=222, Percent_Identity=27.9279279279279, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357171, Length=268, Percent_Identity=27.9850746268657, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653139, Length=212, Percent_Identity=29.7169811320755, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922422, Length=259, Percent_Identity=23.5521235521236, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920382, Length=241, Percent_Identity=26.5560165975104, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650670, Length=263, Percent_Identity=25.4752851711027, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28094; Mature: 27963

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYEKISYERNGDTAIIAFNDDKTLNACGVDTAIELLHAFEVAASEARCTIFTGKGRGF
CCCCHHCCEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
CSGANLGGMGSGPEIAYPGSKPDAGKALDAFYNPLVTAIREHPHPVITAVNGAAAGVGCA
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHH
LGLMGDLVIAGKSAYFLQAFRRIGLVPDGGSTWLLARTIGRVRAMEMALLGEKVSADQAL
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
DWGLVNRVVDDAELLPTALEFAQKLASGPTVALALTRKIIWDASESDFGSALHGERVAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TAGRTDDFKEGVSAFLQKRKAEFKGK
HCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATYEKISYERNGDTAIIAFNDDKTLNACGVDTAIELLHAFEVAASEARCTIFTGKGRGF
CCCHHCCEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
CSGANLGGMGSGPEIAYPGSKPDAGKALDAFYNPLVTAIREHPHPVITAVNGAAAGVGCA
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHH
LGLMGDLVIAGKSAYFLQAFRRIGLVPDGGSTWLLARTIGRVRAMEMALLGEKVSADQAL
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
DWGLVNRVVDDAELLPTALEFAQKLASGPTVALALTRKIIWDASESDFGSALHGERVAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TAGRTDDFKEGVSAFLQKRKAEFKGK
HCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]