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The map label for this gene is crp [C]

Identifier: 114798151

GI number: 114798151

Start: 1495006

End: 1495707

Strand: Reverse

Name: crp [C]

Synonym: HNE_1469

Alternate gene names: 114798151

Gene position: 1495707-1495006 (Counterclockwise)

Preceding gene: 114797371

Following gene: 114799943

Centisome position: 40.37

GC content: 58.12

Gene sequence:

>702_bases
ATGCATATTGCAGGTCAGCTTAACTGGATAAATGAGCTCCCCGCCCCGGCGCGGGACGCTATACGCAATCGGTTCGTTTA
CCGTGACCTTGAGCCCGGCGAGACCATTAAGGAAAGCGGTCAGCCCGCAGAGGGCATGTACCAGGTCCAGTCCGGCTACA
TCAAACTGCTGGCGGATCGCCCGGATGGGGAGCAATCCCTGCTGCTGATCTACATTCGCGGCAACAGCTTTGGGGAATCG
ACCCTGATTGCCCGACGCCCGCACCATCACACAACGATTGCCGCCAGCCCTGCGCGCATCGGTTTCCTGAAACAGAACGA
CTTTGACGAGCTCTACCGTACCTACCCGTCCATTCCCGAAGCGCTCTGCCGAAAATTCGCGACCGCCCTCAGCTCCATGA
TTGCCTATCGGGAAAAGCAGAATGAAACGACGGTCGCCCAAAGGGTTGCCCTGGTCCTGCGCAATCTGGCAGAGATGAGC
GAAACACCCCAGATCGGCGGCCGCCGCGCCATTGATATCCCTATCACGATTGGGGAACTGTCCAGTTTCCTTGGCCTCAC
TCGCCAGACTGTCCAGAAGGAAATATCCCTCCTCAAACGCCGCAACCTGATATCGAAATCGCAAGGCGCCTGGACCGTGT
TGGATATGGCCCTGCTCAGAACGCTCGCTCCGGCAGAGGACGTTCCGGACCTGCTAACATAA

Upstream 100 bases:

>100_bases
AAGGATTTTACATTTTCGGATAAAAGGCGTTCTGTCCGGATATGCCGAAGGGGTTTGCCCTCACAGCGCCCCCGGGGCAG
ACCGTGTTCAGGAGGACGCC

Downstream 100 bases:

>100_bases
GGATCACCGTCTACGGATCATTTGTTGTCTGCCCGGCAGACAATGCGGACTTCTGGCTTTTCAGAATCTTCGACCAGAGC
GCCTCGGCGGCAGGAGACTG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcription Regulator Protein; Catabolite Gene Activator; Crp/Fnr Family Transcriptional Regulator

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MHIAGQLNWINELPAPARDAIRNRFVYRDLEPGETIKESGQPAEGMYQVQSGYIKLLADRPDGEQSLLLIYIRGNSFGES
TLIARRPHHHTTIAASPARIGFLKQNDFDELYRTYPSIPEALCRKFATALSSMIAYREKQNETTVAQRVALVLRNLAEMS
ETPQIGGRRAIDIPITIGELSSFLGLTRQTVQKEISLLKRRNLISKSQGAWTVLDMALLRTLAPAEDVPDLLT

Sequences:

>Translated_233_residues
MHIAGQLNWINELPAPARDAIRNRFVYRDLEPGETIKESGQPAEGMYQVQSGYIKLLADRPDGEQSLLLIYIRGNSFGES
TLIARRPHHHTTIAASPARIGFLKQNDFDELYRTYPSIPEALCRKFATALSSMIAYREKQNETTVAQRVALVLRNLAEMS
ETPQIGGRRAIDIPITIGELSSFLGLTRQTVQKEISLLKRRNLISKSQGAWTVLDMALLRTLAPAEDVPDLLT
>Mature_233_residues
MHIAGQLNWINELPAPARDAIRNRFVYRDLEPGETIKESGQPAEGMYQVQSGYIKLLADRPDGEQSLLLIYIRGNSFGES
TLIARRPHHHTTIAASPARIGFLKQNDFDELYRTYPSIPEALCRKFATALSSMIAYREKQNETTVAQRVALVLRNLAEMS
ETPQIGGRRAIDIPITIGELSSFLGLTRQTVQKEISLLKRRNLISKSQGAWTVLDMALLRTLAPAEDVPDLLT

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26099; Mature: 26099

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIAGQLNWINELPAPARDAIRNRFVYRDLEPGETIKESGQPAEGMYQVQSGYIKLLADR
CCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHCCEEEEEECC
PDGEQSLLLIYIRGNSFGESTLIARRPHHHTTIAASPARIGFLKQNDFDELYRTYPSIPE
CCCCCCEEEEEEECCCCCCCCEEEECCCCCCEEECCCHHEEECCCCCHHHHHHHCCCHHH
ALCRKFATALSSMIAYREKQNETTVAQRVALVLRNLAEMSETPQIGGRRAIDIPITIGEL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECEEHHHH
SSFLGLTRQTVQKEISLLKRRNLISKSQGAWTVLDMALLRTLAPAEDVPDLLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHCC
>Mature Secondary Structure
MHIAGQLNWINELPAPARDAIRNRFVYRDLEPGETIKESGQPAEGMYQVQSGYIKLLADR
CCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHCCEEEEEECC
PDGEQSLLLIYIRGNSFGESTLIARRPHHHTTIAASPARIGFLKQNDFDELYRTYPSIPE
CCCCCCEEEEEEECCCCCCCCEEEECCCCCCEEECCCHHEEECCCCCHHHHHHHCCCHHH
ALCRKFATALSSMIAYREKQNETTVAQRVALVLRNLAEMSETPQIGGRRAIDIPITIGEL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECEEHHHH
SSFLGLTRQTVQKEISLLKRRNLISKSQGAWTVLDMALLRTLAPAEDVPDLLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA