| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is phbB [H]
Identifier: 114798054
GI number: 114798054
Start: 3548159
End: 3548884
Strand: Direct
Name: phbB [H]
Synonym: HNE_3404
Alternate gene names: 114798054
Gene position: 3548159-3548884 (Clockwise)
Preceding gene: 114800276
Following gene: 114800073
Centisome position: 95.77
GC content: 60.61
Gene sequence:
>726_bases ATGGCGAAAACGGCTCTGGTGACCGGCGGTACGCGCGGCATCGGCAAGGCAATCAGCGAAATGCTGCAAGCGAAAGGCTA CTCAGTGGCCGCCAATTATGGTGGCAATGACGCAGCCGCCGCAGCATTTTCAAAGGAAACCGGCATCAAGGTCTTCAAAT TCGACGTGGCCGATTATGACGCGGTCGGCGTGGGCCTGAAGGCGGTCGAGGCGGAAGTCGGTCCCGTGGACGTGCTGGTG AATAATGCCGGGATCACCCGCGACGCGCCCTTCCACAAGATGACGCTGGCCCATTGGCAGGAGGTCATCAATGTCGACCT GACCTCCGCCTTCAACGTCACCCGGCAGGTATGGGACGGGATGCGGGAGCGCAATTTCGGCCGGATCATCAATATTTCCT CGATCAACGGCCAGAAAGGCCAGTTCACGCAGGCCAACTATTCTGCCGCCAAGGCCGGCCTGATCGGCTTCACCAAGGCG CTGGCCTATGAAGGCGCCAAGAAGGGAATCACCTCGAACGTCGTGGCGCCGGGCTATATCGACACCGAGATGTTGCAGGC GGTGAAGCCCGAAGTACTCGAAGGGATCATTGCCACGATCCCGGTGGGGCGCCTGGGCAAGGCCGAAGAGATCGCCTCGA TGTGCGCTTATCTGGCGTCCGAAGAAGCCGCCTTCATCAATGGCGCGACCATGACGGTGAACGGCGCGCAGTATATCGCG GGCTGA
Upstream 100 bases:
>100_bases AATATTTGCACAGAACCCTCACAAGACCAATGCGCTATTGATGTGGACCCCGCTTGTAGGCAAGGCTGGGGACAACGAGA CATTGGGAGGAGTTCATACC
Downstream 100 bases:
>100_bases TAAAACGCGGCCTTGTCCCGTGGATAAGGCCGCAAAAAAACTCCAACGAAACCTCCAACGAGGCGTGAAAAACTCCAACG GCGTTGGAGTTTTTTGCGGT
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 241; Mature: 240
Protein sequence:
>241_residues MAKTALVTGGTRGIGKAISEMLQAKGYSVAANYGGNDAAAAAFSKETGIKVFKFDVADYDAVGVGLKAVEAEVGPVDVLV NNAGITRDAPFHKMTLAHWQEVINVDLTSAFNVTRQVWDGMRERNFGRIINISSINGQKGQFTQANYSAAKAGLIGFTKA LAYEGAKKGITSNVVAPGYIDTEMLQAVKPEVLEGIIATIPVGRLGKAEEIASMCAYLASEEAAFINGATMTVNGAQYIA G
Sequences:
>Translated_241_residues MAKTALVTGGTRGIGKAISEMLQAKGYSVAANYGGNDAAAAAFSKETGIKVFKFDVADYDAVGVGLKAVEAEVGPVDVLV NNAGITRDAPFHKMTLAHWQEVINVDLTSAFNVTRQVWDGMRERNFGRIINISSINGQKGQFTQANYSAAKAGLIGFTKA LAYEGAKKGITSNVVAPGYIDTEMLQAVKPEVLEGIIATIPVGRLGKAEEIASMCAYLASEEAAFINGATMTVNGAQYIA G >Mature_240_residues AKTALVTGGTRGIGKAISEMLQAKGYSVAANYGGNDAAAAAFSKETGIKVFKFDVADYDAVGVGLKAVEAEVGPVDVLVN NAGITRDAPFHKMTLAHWQEVINVDLTSAFNVTRQVWDGMRERNFGRIINISSINGQKGQFTQANYSAAKAGLIGFTKAL AYEGAKKGITSNVVAPGYIDTEMLQAVKPEVLEGIIATIPVGRLGKAEEIASMCAYLASEEAAFINGATMTVNGAQYIAG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=38.8888888888889, Blast_Score=139, Evalue=2e-33, Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=35.7142857142857, Blast_Score=133, Evalue=1e-31, Organism=Homo sapiens, GI4504505, Length=231, Percent_Identity=35.9307359307359, Blast_Score=120, Evalue=9e-28, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=30.6122448979592, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI7705925, Length=236, Percent_Identity=29.2372881355932, Blast_Score=97, Evalue=9e-21, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=31.0756972111554, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI4758504, Length=246, Percent_Identity=32.1138211382114, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=29.951690821256, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=33, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=31.6, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=27.8969957081545, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=32.2751322751323, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI4503301, Length=208, Percent_Identity=29.3269230769231, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI59889578, Length=209, Percent_Identity=30.622009569378, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI83715985, Length=247, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503817, Length=186, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=28.2786885245902, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=33.160621761658, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI7705855, Length=204, Percent_Identity=29.9019607843137, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=33.7278106508876, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI210032110, Length=186, Percent_Identity=26.3440860215054, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=47.2803347280335, Blast_Score=205, Evalue=2e-54, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=32.7868852459016, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=32.1285140562249, Blast_Score=124, Evalue=4e-30, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=35.2697095435685, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=32.9268292682927, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=29.6153846153846, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=31.1475409836066, Blast_Score=109, Evalue=1e-25, Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.1652892561983, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=29.9180327868852, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=3e-18, Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=30.8988764044944, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=5e-13, Organism=Caenorhabditis elegans, GI25147288, Length=238, Percent_Identity=43.2773109243698, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=39.2405063291139, Blast_Score=156, Evalue=8e-39, Organism=Caenorhabditis elegans, GI17568967, Length=213, Percent_Identity=37.0892018779343, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=30.1204819277108, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=31.6, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=29.5275590551181, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.5140562248996, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=31.1740890688259, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=29.1497975708502, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=29.1497975708502, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=25.1937984496124, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=29.9180327868852, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=25.968992248062, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.1853281853282, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=26.9430051813472, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562904, Length=255, Percent_Identity=25.8823529411765, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=25.3787878787879, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=27.1653543307087, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=27.1317829457364, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=236, Percent_Identity=36.0169491525424, Blast_Score=121, Evalue=9e-29, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=28.1124497991968, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6320089, Length=191, Percent_Identity=27.7486910994764, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24639444, Length=239, Percent_Identity=37.6569037656904, Blast_Score=135, Evalue=2e-32, Organism=Drosophila melanogaster, GI18859837, Length=231, Percent_Identity=35.0649350649351, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=31.4516129032258, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=32.9411764705882, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=31.2236286919831, Blast_Score=96, Evalue=1e-20, Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=29.8755186721992, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.5220883534137, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=177, Percent_Identity=31.638418079096, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24644337, Length=179, Percent_Identity=31.8435754189944, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI24581726, Length=145, Percent_Identity=29.6551724137931, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331218, Length=193, Percent_Identity=31.6062176165803, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24665243, Length=193, Percent_Identity=31.6062176165803, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24665247, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=200, Percent_Identity=29.5, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24656154, Length=210, Percent_Identity=29.5238095238095, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI19922628, Length=210, Percent_Identity=29.5238095238095, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24665264, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 25275; Mature: 25144
Theoretical pI: Translated: 6.55; Mature: 6.55
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKTALVTGGTRGIGKAISEMLQAKGYSVAANYGGNDAAAAAFSKETGIKVFKFDVADYD CCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC AVGVGLKAVEAEVGPVDVLVNNAGITRDAPFHKMTLAHWQEVINVDLTSAFNVTRQVWDG HHCCCHHEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH MRERNFGRIINISSINGQKGQFTQANYSAAKAGLIGFTKALAYEGAKKGITSNVVAPGYI HHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC DTEMLQAVKPEVLEGIIATIPVGRLGKAEEIASMCAYLASEEAAFINGATMTVNGAQYIA CHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCC G C >Mature Secondary Structure AKTALVTGGTRGIGKAISEMLQAKGYSVAANYGGNDAAAAAFSKETGIKVFKFDVADYD CCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC AVGVGLKAVEAEVGPVDVLVNNAGITRDAPFHKMTLAHWQEVINVDLTSAFNVTRQVWDG HHCCCHHEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH MRERNFGRIINISSINGQKGQFTQANYSAAKAGLIGFTKALAYEGAKKGITSNVVAPGYI HHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC DTEMLQAVKPEVLEGIIATIPVGRLGKAEEIASMCAYLASEEAAFINGATMTVNGAQYIA CHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCC G C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2546004; 3286259 [H]