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The map label for this gene is lspA2 [H]

Identifier: 114797959

GI number: 114797959

Start: 1771095

End: 1771559

Strand: Direct

Name: lspA2 [H]

Synonym: HNE_1728

Alternate gene names: 114797959

Gene position: 1771095-1771559 (Clockwise)

Preceding gene: 114799140

Following gene: 114799205

Centisome position: 47.8

GC content: 58.06

Gene sequence:

>465_bases
ATGAACAGGCTATTGGGCGCAACTGCATTGCTCGCCGTTCCGGCACTCGACCTCGGGACGAAGGCTTGGGCGCGATCGCG
CTTGCACGAAGCACAACCGTTGGAGTTGCTGCCATTTTTCGACCTGACACTAAGCTTTAATCGCGGCGTATCTTTCGGGC
TCTTCGGAACGGCATCGAGCGCTTGGCCTGTCATTGTCATCACAGCGGCAATCACGGTGGCTTTGGCATTTTGGTTCTGG
CGCACGACGCGATCAGGTGAGCAGCTTGCGTTGGCGCTAATCGTCGGCGGCGCATTAGGGAACCTAATCGACCGGGTGCA
CCGCGGCGCTGTGACGGACTTTCTCGACTTCCATGCCGCCGGTTGGCATTGGCCGGCTTTTAACCTGGCCGACACCGCAA
TCGTGTGTGGTGCGGTCTTGCTTCTTTGCCATTCACTTAGCCCGCGCAATCAGACTTCCACTTAA

Upstream 100 bases:

>100_bases
GGCCCGACCTTATCGCGGGCGCAGCCATTGCATTCCTTTTCCTGCACTCGTCGCTGCAGATCATCCGGGATTCGCGCCGT
GAACTCCGTGAGGTGGTGGA

Downstream 100 bases:

>100_bases
CAACCTCAGTGGTACGTGCCCCGCCTGCTACGGGACAGATTTCAGGCTTCAACGAAGGAATAATCTCTCGCTCGGGTCCC
CGCATCCTGAACGACCGCTG

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNRLLGATALLAVPALDLGTKAWARSRLHEAQPLELLPFFDLTLSFNRGVSFGLFGTASSAWPVIVITAAITVALAFWFW
RTTRSGEQLALALIVGGALGNLIDRVHRGAVTDFLDFHAAGWHWPAFNLADTAIVCGAVLLLCHSLSPRNQTST

Sequences:

>Translated_154_residues
MNRLLGATALLAVPALDLGTKAWARSRLHEAQPLELLPFFDLTLSFNRGVSFGLFGTASSAWPVIVITAAITVALAFWFW
RTTRSGEQLALALIVGGALGNLIDRVHRGAVTDFLDFHAAGWHWPAFNLADTAIVCGAVLLLCHSLSPRNQTST
>Mature_154_residues
MNRLLGATALLAVPALDLGTKAWARSRLHEAQPLELLPFFDLTLSFNRGVSFGLFGTASSAWPVIVITAAITVALAFWFW
RTTRSGEQLALALIVGGALGNLIDRVHRGAVTDFLDFHAAGWHWPAFNLADTAIVCGAVLLLCHSLSPRNQTST

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=143, Percent_Identity=35.6643356643357, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 16595; Mature: 16595

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLLGATALLAVPALDLGTKAWARSRLHEAQPLELLPFFDLTLSFNRGVSFGLFGTASS
CCCHHHHHHHHHHHCHHCCHHHHHHHHHCCCCCCEEECHHHEEEECCCCCEEEEECCCCC
AWPVIVITAAITVALAFWFWRTTRSGEQLALALIVGGALGNLIDRVHRGAVTDFLDFHAA
CCHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GWHWPAFNLADTAIVCGAVLLLCHSLSPRNQTST
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNRLLGATALLAVPALDLGTKAWARSRLHEAQPLELLPFFDLTLSFNRGVSFGLFGTASS
CCCHHHHHHHHHHHCHHCCHHHHHHHHHCCCCCCEEECHHHEEEECCCCCEEEEECCCCC
AWPVIVITAAITVALAFWFWRTTRSGEQLALALIVGGALGNLIDRVHRGAVTDFLDFHAA
CCHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GWHWPAFNLADTAIVCGAVLLLCHSLSPRNQTST
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA