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The map label for this gene is betT [C]

Identifier: 114797952

GI number: 114797952

Start: 1519664

End: 1521649

Strand: Direct

Name: betT [C]

Synonym: HNE_1490

Alternate gene names: 114797952

Gene position: 1519664-1521649 (Clockwise)

Preceding gene: 114799886

Following gene: 114800459

Centisome position: 41.02

GC content: 60.32

Gene sequence:

>1986_bases
ATGTTCAAGCCATTCATCATCAACCGGCCCGTATTCTTTGGCTCAGTCTTCATCACGCTGGTGTTCCTGTCTGTCGGGGT
CTTCTTTCCCACACGCGCTGAGACCATTTTCGGCACGATCGAGCGCTTCCTGCTGGAGAATTTTGGCTGGTTCTATCTCC
TGGCTGTGGGGATCGTCCTGGTCGCCGTCCTTCTGATGTGTCTGGGACGCTACGGCCGCCTCCGGCTCGGCCCGGATGAC
GCCACGCCGGACTTTGCCTTCCTGTCCTGGCTGGCCATGCTGTTTGCCGCCGGTATGGGGATCGGCCTGATGTTCTATGC
CGTGGGGGAGCCGATGAGCCACTTCATGGCGCCGCCGACCGCAGAGCCGCGCACCATCGAAGCGACACGGGAAGCGATGG
CGGTGACCTTCTTTCACTGGGGCATACATGCCTGGGCGGTATACGCTGTGGTCGGCCTCTCGCTGGCGTATTTCGGGTAT
CGCTACAATCTGCCCCTGACCATAAGGTCGGGCCTCTATCCGCTCCTGAAAGAGAAGATCAACGGTCCGATCGGACACGC
CGTGGATATCTTCGCCGTTGTCGGAACGCTCTTTGGCATCGCCACATCGATGGGCTTCGGGGTTACGCAGATCAATGCGG
GGCTCAACCATCTGATCGGTCTGCCGATCAGTCCGCAGATCCAGATTACCCTCATTGCAGGGATCACGCTTCTGGCAACT
ATTTCGGTTGTCACAGGTCTCGACAAGGGGGTGCGCATCCTTTCGGAAACCAATCTGGTTATTGCAGTCCTTCTGATGCT
TTTTGTGCTGGTCGTAGGGCCAACGGCCGATCTGCTGCGCAGCTTCGTTCAGAATCTAGGGCTCTACCTGGACTCCCTGC
TGCTGCGGACGTTCAACATCTACGCCTATGAACCGACCCCCTGGATCGATGCGTGGACCCTGTTCTACTGGACCTGGTGG
ATTTCCTGGTCGCCCTTTGTCGGCATGTTCATTGCCCGGATTTCCCGGGGGCGCACCGTTCGCGAATTCATCCTCGCTGT
CCTCTTCATTCCCGCGGGTTTTACGTTCTTCTGGATGACGGTGTTCGGGAATACCGCCATATCGATTGATACAGGCGTCG
CGGCTGGCGAGCTTGGCCAGGCCATTGCGGCCGACATCTCGGTCGGGCTGTTTCAGTTCTTCGAATATCTGCCATTCCCG
GCCCTGACCTCGACGCTCGCCGTCCTGCTTGTCACGATATTCTTCATTACCTCCTCCGACTCCGGATCATTGGTCATTGA
TTCGATCGCCGCAGGCGGCGAAACCGTGACCACGACCGGGCAACGCGTCTTCTGGTGTGCGCTTCAGGGCATTGTCGCCG
GATCCCTGCTTCTTGCCGGCGGGCTGGACGCCCTGCAATCGGCGACGATTGCGAGCGCCCTGCCTTTCACCTTCGTGCTG
CTCGCGCTTGTCTGGTCTCTGGTTGTGGGTATGCGGGCTGACCTTCATCAGCAGGCCCATGCCGCTGCGCGCCATGTGCC
CGGCGCGCAGCCAGCTGCCGGACTGACCTGGCAGCGGCGTCTTGCGCTCATTCTGCATGCGCCGACGCAAGCCGAGGTCG
AGAAGTTCATCGCCCGTGAAGTCAGGCCCGCCCTTGAGCAGGTGGCGCAGGAGCTGAGCGACACAGGCCGGCCAACGCAG
GTGGCGCAAGAGGAACATGGCGGCGTCGCGCTCCGCTCACCCGCCGACGGAAGCCGCGATTTTGTGTATGGGGTGAGCGT
TACCCCGCAGCGGCTAGCCTCCCTTTCTCCCTTGCAGACGAGACCGGAATTCCGCTTTGAGGCCCGCACCTATTTCTCCA
GTGGCGGGCGGGGCTATGACGTGATGGGCATGCACCGGGAGCAACTGATTGCAGATATCCTGGTTCAGTTCGAACGGTAC
CTCGCCGTGGTGCAATCCCCAGAAGCGCAATTGCTGCATGGTGCGCCGGGGCATGATTTTGAATAG

Upstream 100 bases:

>100_bases
ACTGGCGACGCGCAAGTTCCGGACCGGTTAGCGGAGGCGACGTCAGATCGTTTCACAGACGCACGGAACCAGAGCACCTG
ACAGAAAAGCAGCCAGCGTT

Downstream 100 bases:

>100_bases
TGCGGTCAAAAAAACCGACACGGCCGCCAATCGGGCAAGTACCTCCGCTGATTGGCATCTTTCTGTAAAACACCCGGTTC
CGGAGACTTACCCGATAAAT

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MFKPFIINRPVFFGSVFITLVFLSVGVFFPTRAETIFGTIERFLLENFGWFYLLAVGIVLVAVLLMCLGRYGRLRLGPDD
ATPDFAFLSWLAMLFAAGMGIGLMFYAVGEPMSHFMAPPTAEPRTIEATREAMAVTFFHWGIHAWAVYAVVGLSLAYFGY
RYNLPLTIRSGLYPLLKEKINGPIGHAVDIFAVVGTLFGIATSMGFGVTQINAGLNHLIGLPISPQIQITLIAGITLLAT
ISVVTGLDKGVRILSETNLVIAVLLMLFVLVVGPTADLLRSFVQNLGLYLDSLLLRTFNIYAYEPTPWIDAWTLFYWTWW
ISWSPFVGMFIARISRGRTVREFILAVLFIPAGFTFFWMTVFGNTAISIDTGVAAGELGQAIAADISVGLFQFFEYLPFP
ALTSTLAVLLVTIFFITSSDSGSLVIDSIAAGGETVTTTGQRVFWCALQGIVAGSLLLAGGLDALQSATIASALPFTFVL
LALVWSLVVGMRADLHQQAHAAARHVPGAQPAAGLTWQRRLALILHAPTQAEVEKFIAREVRPALEQVAQELSDTGRPTQ
VAQEEHGGVALRSPADGSRDFVYGVSVTPQRLASLSPLQTRPEFRFEARTYFSSGGRGYDVMGMHREQLIADILVQFERY
LAVVQSPEAQLLHGAPGHDFE

Sequences:

>Translated_661_residues
MFKPFIINRPVFFGSVFITLVFLSVGVFFPTRAETIFGTIERFLLENFGWFYLLAVGIVLVAVLLMCLGRYGRLRLGPDD
ATPDFAFLSWLAMLFAAGMGIGLMFYAVGEPMSHFMAPPTAEPRTIEATREAMAVTFFHWGIHAWAVYAVVGLSLAYFGY
RYNLPLTIRSGLYPLLKEKINGPIGHAVDIFAVVGTLFGIATSMGFGVTQINAGLNHLIGLPISPQIQITLIAGITLLAT
ISVVTGLDKGVRILSETNLVIAVLLMLFVLVVGPTADLLRSFVQNLGLYLDSLLLRTFNIYAYEPTPWIDAWTLFYWTWW
ISWSPFVGMFIARISRGRTVREFILAVLFIPAGFTFFWMTVFGNTAISIDTGVAAGELGQAIAADISVGLFQFFEYLPFP
ALTSTLAVLLVTIFFITSSDSGSLVIDSIAAGGETVTTTGQRVFWCALQGIVAGSLLLAGGLDALQSATIASALPFTFVL
LALVWSLVVGMRADLHQQAHAAARHVPGAQPAAGLTWQRRLALILHAPTQAEVEKFIAREVRPALEQVAQELSDTGRPTQ
VAQEEHGGVALRSPADGSRDFVYGVSVTPQRLASLSPLQTRPEFRFEARTYFSSGGRGYDVMGMHREQLIADILVQFERY
LAVVQSPEAQLLHGAPGHDFE
>Mature_661_residues
MFKPFIINRPVFFGSVFITLVFLSVGVFFPTRAETIFGTIERFLLENFGWFYLLAVGIVLVAVLLMCLGRYGRLRLGPDD
ATPDFAFLSWLAMLFAAGMGIGLMFYAVGEPMSHFMAPPTAEPRTIEATREAMAVTFFHWGIHAWAVYAVVGLSLAYFGY
RYNLPLTIRSGLYPLLKEKINGPIGHAVDIFAVVGTLFGIATSMGFGVTQINAGLNHLIGLPISPQIQITLIAGITLLAT
ISVVTGLDKGVRILSETNLVIAVLLMLFVLVVGPTADLLRSFVQNLGLYLDSLLLRTFNIYAYEPTPWIDAWTLFYWTWW
ISWSPFVGMFIARISRGRTVREFILAVLFIPAGFTFFWMTVFGNTAISIDTGVAAGELGQAIAADISVGLFQFFEYLPFP
ALTSTLAVLLVTIFFITSSDSGSLVIDSIAAGGETVTTTGQRVFWCALQGIVAGSLLLAGGLDALQSATIASALPFTFVL
LALVWSLVVGMRADLHQQAHAAARHVPGAQPAAGLTWQRRLALILHAPTQAEVEKFIAREVRPALEQVAQELSDTGRPTQ
VAQEEHGGVALRSPADGSRDFVYGVSVTPQRLASLSPLQTRPEFRFEARTYFSSGGRGYDVMGMHREQLIADILVQFERY
LAVVQSPEAQLLHGAPGHDFE

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=677, Percent_Identity=38.4047267355982, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI1788102, Length=474, Percent_Identity=29.1139240506329, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786224, Length=506, Percent_Identity=27.8656126482213, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 72227; Mature: 72227

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKPFIINRPVFFGSVFITLVFLSVGVFFPTRAETIFGTIERFLLENFGWFYLLAVGIVL
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VAVLLMCLGRYGRLRLGPDDATPDFAFLSWLAMLFAAGMGIGLMFYAVGEPMSHFMAPPT
HHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCC
AEPRTIEATREAMAVTFFHWGIHAWAVYAVVGLSLAYFGYRYNLPLTIRSGLYPLLKEKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECCCCHHHHHHHC
NGPIGHAVDIFAVVGTLFGIATSMGFGVTQINAGLNHLIGLPISPQIQITLIAGITLLAT
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHCCCCCCCCEEEEHHHHHHHHHH
ISVVTGLDKGVRILSETNLVIAVLLMLFVLVVGPTADLLRSFVQNLGLYLDSLLLRTFNI
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHE
YAYEPTPWIDAWTLFYWTWWISWSPFVGMFIARISRGRTVREFILAVLFIPAGFTFFWMT
EEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
VFGNTAISIDTGVAAGELGQAIAADISVGLFQFFEYLPFPALTSTLAVLLVTIFFITSSD
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
SGSLVIDSIAAGGETVTTTGQRVFWCALQGIVAGSLLLAGGLDALQSATIASALPFTFVL
CCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LALVWSLVVGMRADLHQQAHAAARHVPGAQPAAGLTWQRRLALILHAPTQAEVEKFIARE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEECCCHHHHHHHHHHH
VRPALEQVAQELSDTGRPTQVAQEEHGGVALRSPADGSRDFVYGVSVTPQRLASLSPLQT
HHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCEEEECCCCHHHHHCCCCCCC
RPEFRFEARTYFSSGGRGYDVMGMHREQLIADILVQFERYLAVVQSPEAQLLHGAPGHDF
CCCCEEHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCC
E
C
>Mature Secondary Structure
MFKPFIINRPVFFGSVFITLVFLSVGVFFPTRAETIFGTIERFLLENFGWFYLLAVGIVL
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VAVLLMCLGRYGRLRLGPDDATPDFAFLSWLAMLFAAGMGIGLMFYAVGEPMSHFMAPPT
HHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCC
AEPRTIEATREAMAVTFFHWGIHAWAVYAVVGLSLAYFGYRYNLPLTIRSGLYPLLKEKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECCCCHHHHHHHC
NGPIGHAVDIFAVVGTLFGIATSMGFGVTQINAGLNHLIGLPISPQIQITLIAGITLLAT
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHCCCCCCCCEEEEHHHHHHHHHH
ISVVTGLDKGVRILSETNLVIAVLLMLFVLVVGPTADLLRSFVQNLGLYLDSLLLRTFNI
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHE
YAYEPTPWIDAWTLFYWTWWISWSPFVGMFIARISRGRTVREFILAVLFIPAGFTFFWMT
EEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
VFGNTAISIDTGVAAGELGQAIAADISVGLFQFFEYLPFPALTSTLAVLLVTIFFITSSD
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
SGSLVIDSIAAGGETVTTTGQRVFWCALQGIVAGSLLLAGGLDALQSATIASALPFTFVL
CCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LALVWSLVVGMRADLHQQAHAAARHVPGAQPAAGLTWQRRLALILHAPTQAEVEKFIARE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEECCCHHHHHHHHHHH
VRPALEQVAQELSDTGRPTQVAQEEHGGVALRSPADGSRDFVYGVSVTPQRLASLSPLQT
HHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCEEEECCCCHHHHHCCCCCCC
RPEFRFEARTYFSSGGRGYDVMGMHREQLIADILVQFERYLAVVQSPEAQLLHGAPGHDF
CCCCEEHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]