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The map label for this gene is csgA [H]

Identifier: 114797653

GI number: 114797653

Start: 3400244

End: 3400954

Strand: Direct

Name: csgA [H]

Synonym: HNE_3232

Alternate gene names: 114797653

Gene position: 3400244-3400954 (Clockwise)

Preceding gene: 114798425

Following gene: 114799400

Centisome position: 91.77

GC content: 65.82

Gene sequence:

>711_bases
ATGATCGCAGCAGTTTTCGGCAGTTCCGGCGGTATTGGCCGCGCCCTGGTCAGCGCGCTGCTCGCGCGCGGCGGCTACAC
GCACGTCTTCGCCATCTCCCGCAGCGGCGCCGCCCATGAGGGCGCGCAGGCCCGGCAGGCCGACTTTCTCGATGCGGCAG
ACCTCGCCGCCCTTGCCGAGGAAATCGCGGCAGCCGGGCCACTCTGCCTCGCCATCGTAGCCAGCGGCCTCCTCTCCGAT
GGCGACGCGCTGCAGCCGGAAAAAACCTATCGCCATCATTTGCTCGAAAACTTCCAGCGCGTGTTCGAGGCCAACACCTT
TGCGCCCGGCCTTATCGCCAAACACATGCTGCCGCTTATGCCGAAGAAGGAGCGCGGCGTGTTTGCTGCCCTCTCCGCCC
GCGTCGGGTCTATAACGGACAACCGCCTCGGCGGCTGGCACGCCTACCGCGCCTCCAAAGCCGCCCTCAACATGCTGATC
CGCAACTACGCCATCGAGCAGGCAAGACGCGCGCCCGGCGCGATCTGTGTTGGCCTTCATCCGGGCACGGTGGATACCGG
CCTCTCCAGGCCCTTCCAGTCCGGCGTCTCCGAAGGCAAGCTGTTCACCCCGGACCAATCGGCCGGCTACCTGCTGGATG
TCATCGGTAATCTCACTCCGGAAGACAGCGGCAAATGCTTCGACTGGGCCGGCAAGGAAGTGCCCGCTTGA

Upstream 100 bases:

>100_bases
GAGCACATCATTCGTAATGATGGGGTCAGGTGTTCAAGTCACCTAAGCGGCACCATTTCCCCTTTCCCTCCGCCCTGTGC
GCCTTATCTCGCTGCCCATC

Downstream 100 bases:

>100_bases
AGCCCCGGGTCTAAAGCCGGAACTGCCCCTCAATGACCGTCACCGCCCGGCCGACCAACTTTACCCGGTCGCCCTCCAGG
CGCACATCCACGCGCGCGCC

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: C signal [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MIAAVFGSSGGIGRALVSALLARGGYTHVFAISRSGAAHEGAQARQADFLDAADLAALAEEIAAAGPLCLAIVASGLLSD
GDALQPEKTYRHHLLENFQRVFEANTFAPGLIAKHMLPLMPKKERGVFAALSARVGSITDNRLGGWHAYRASKAALNMLI
RNYAIEQARRAPGAICVGLHPGTVDTGLSRPFQSGVSEGKLFTPDQSAGYLLDVIGNLTPEDSGKCFDWAGKEVPA

Sequences:

>Translated_236_residues
MIAAVFGSSGGIGRALVSALLARGGYTHVFAISRSGAAHEGAQARQADFLDAADLAALAEEIAAAGPLCLAIVASGLLSD
GDALQPEKTYRHHLLENFQRVFEANTFAPGLIAKHMLPLMPKKERGVFAALSARVGSITDNRLGGWHAYRASKAALNMLI
RNYAIEQARRAPGAICVGLHPGTVDTGLSRPFQSGVSEGKLFTPDQSAGYLLDVIGNLTPEDSGKCFDWAGKEVPA
>Mature_236_residues
MIAAVFGSSGGIGRALVSALLARGGYTHVFAISRSGAAHEGAQARQADFLDAADLAALAEEIAAAGPLCLAIVASGLLSD
GDALQPEKTYRHHLLENFQRVFEANTFAPGLIAKHMLPLMPKKERGVFAALSARVGSITDNRLGGWHAYRASKAALNMLI
RNYAIEQARRAPGAICVGLHPGTVDTGLSRPFQSGVSEGKLFTPDQSAGYLLDVIGNLTPEDSGKCFDWAGKEVPA

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322779, Length=255, Percent_Identity=28.6274509803922, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 24768; Mature: 24768

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAVFGSSGGIGRALVSALLARGGYTHVFAISRSGAAHEGAQARQADFLDAADLAALAE
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
EIAAAGPLCLAIVASGLLSDGDALQPEKTYRHHLLENFQRVFEANTFAPGLIAKHMLPLM
HHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PKKERGVFAALSARVGSITDNRLGGWHAYRASKAALNMLIRNYAIEQARRAPGAICVGLH
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
PGTVDTGLSRPFQSGVSEGKLFTPDQSAGYLLDVIGNLTPEDSGKCFDWAGKEVPA
CCCCCHHCCCHHHHCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MIAAVFGSSGGIGRALVSALLARGGYTHVFAISRSGAAHEGAQARQADFLDAADLAALAE
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
EIAAAGPLCLAIVASGLLSDGDALQPEKTYRHHLLENFQRVFEANTFAPGLIAKHMLPLM
HHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PKKERGVFAALSARVGSITDNRLGGWHAYRASKAALNMLIRNYAIEQARRAPGAICVGLH
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
PGTVDTGLSRPFQSGVSEGKLFTPDQSAGYLLDVIGNLTPEDSGKCFDWAGKEVPA
CCCCCHHCCCHHHHCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]