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The map label for this gene is hyuA [H]

Identifier: 114797626

GI number: 114797626

Start: 2635451

End: 2637037

Strand: Direct

Name: hyuA [H]

Synonym: HNE_2503

Alternate gene names: 114797626

Gene position: 2635451-2637037 (Clockwise)

Preceding gene: 114799415

Following gene: 114800407

Centisome position: 71.13

GC content: 63.83

Gene sequence:

>1587_bases
ATGCAACGGATCAGCGAAAAGAAGCCCCTCCGCATCGGTGTGGATGTTGGCGGAACGAACACGGACGCCGTCCTGATGCA
GGGGGAGCGCGTGCTTGCCTCGACAAAGTCCCCGACGACCCGGTCTGTGCGGGACGGCATTGTCAGCGCCATCTCCGCCG
TCATCGGGTCCGCCGGCGCTGCCGTCAGCGATATTTCCGTGGTCTCAATCGGCACGACCCATTTCACCAACGCCTTCGTG
CAGCGCCGCGGTCTTGACCGGGTGGGTGTGATCCGGATTGCCCTGCCCGCCGCTCAGGCACTCCCCCCCATGACAGACTG
GCCCGAAGATATTGCCAGCGCTATCGGCGGGCAGACATATGCTGTCAGGGGTGGCTACCAGTATGATGGCCGCATCAATG
CGGACCTCGACGAACTGGCCGTCGCCGACGCAGCGAGAAAACTCCGCGCAGAGGGCCTGGCTTCGATCGCGCTCTCGGCC
CTCTTCGCTCCGGTGAACGACGCCATGGAGCGCAGGGCCAGCGACATCATCCGGAATGAATATCCCGACTGCACGCTGAC
CCTCTCCTCCCGGATCGGGCGGATCGGACTGCTCGAGCGGGAGAATGCCGGGATCATGAATGCCAGTCTTGCCAGCCTCG
CGCGGGAGACCGTATCCGGGTTCCGCTCCGCGCTCGCCGAGCTGGGCATTATAGCGCCTTTTTATGTGTCCCAGAACGAT
GGCACGCTGATGAACGCAGAGTTCGTCGAGCAGTATCCGGTTCTGACTTTCGCTTCCGGCCCGACCAATTCGATGCGCGG
CGCCGCCTATCTGTCCGGACTGAAAGACGCGCTGGTGGCCGATATCGGGGGCACAACCACCGATATCGGGGTTCTCAGCA
ACGGATTTCCCAGGGAATCTTCGGTGATGGTCGATATAGGCGGGGTACGGACCAATTTCCGGATGCCTGACATAATAGCA
CTCGGGCTCGGAGGCGGCAGTATCGTTACCCCCCTGAGCGACGGCACGGTCCGGATCGGTCCCCAGTCTGTCGGATATGA
CATCACCACGCAGGCGCTCGTATTCGGGGGCACAACGCTGACAACCACCGATCTGGCCGTGGCGGCCGGCTATGCCGACA
TCGGAGACCGGTCCCGTGTGGCAGGCCTAGATTCCCAGCTCGTGGAGCGCGGGATCACCGAGATACACCGGCTTGTCGAA
ACAGGCGTTGACCGGATGAAGACCAGCGGGGACGCCGCCCCGCTCATCCTGGTAGGCGGCGGCGCCATCCTCATCAACCG
CGAGATCAGAGGCGTTTCTGACATGCGCACGCACCGCGATGCCGGTGTGGCCAATGCGATCGGAGCGTCCATCGCCCAGA
TCGGTGGCGAGACCGACAAGGTCTACGCCTACGATACAGATGGCCGGGACGCAGCAATGGCGGACGCCATCAGCAGCGCC
CGGGCGCGCGCCGTTGCCGCTGGCGCCGATGCAGCCAGCATCGAAATCATGGACATTGAGGAACTGCCCCTCGCCTACAT
CCCGGGCGGCGCGGTCCGGCTGAGAGTAAAGGTAGCGGGCAACCTCGCTGCGGCAGGAGCAGACTGA

Upstream 100 bases:

>100_bases
AATCCTGTAAGCAACCTACTAATTTAAGCCAGACCGGGGCCCGGCAATTGGCACTAGCGTCTGCTTTCCAAGACACCTCC
CCTCTTGTCGAAAGCAGCAG

Downstream 100 bases:

>100_bases
ACATGGCACAGACACCTTCCCTCCCGCGCAGCCTCGCCGTCTCCGGTCACACGTCCGGGGACGAACTTGTCCTGTCGGCG
GCAGATCTCCACGACTTCGC

Product: hydantoinase/oxoprolinase family protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MQRISEKKPLRIGVDVGGTNTDAVLMQGERVLASTKSPTTRSVRDGIVSAISAVIGSAGAAVSDISVVSIGTTHFTNAFV
QRRGLDRVGVIRIALPAAQALPPMTDWPEDIASAIGGQTYAVRGGYQYDGRINADLDELAVADAARKLRAEGLASIALSA
LFAPVNDAMERRASDIIRNEYPDCTLTLSSRIGRIGLLERENAGIMNASLASLARETVSGFRSALAELGIIAPFYVSQND
GTLMNAEFVEQYPVLTFASGPTNSMRGAAYLSGLKDALVADIGGTTTDIGVLSNGFPRESSVMVDIGGVRTNFRMPDIIA
LGLGGGSIVTPLSDGTVRIGPQSVGYDITTQALVFGGTTLTTTDLAVAAGYADIGDRSRVAGLDSQLVERGITEIHRLVE
TGVDRMKTSGDAAPLILVGGGAILINREIRGVSDMRTHRDAGVANAIGASIAQIGGETDKVYAYDTDGRDAAMADAISSA
RARAVAAGADAASIEIMDIEELPLAYIPGGAVRLRVKVAGNLAAAGAD

Sequences:

>Translated_528_residues
MQRISEKKPLRIGVDVGGTNTDAVLMQGERVLASTKSPTTRSVRDGIVSAISAVIGSAGAAVSDISVVSIGTTHFTNAFV
QRRGLDRVGVIRIALPAAQALPPMTDWPEDIASAIGGQTYAVRGGYQYDGRINADLDELAVADAARKLRAEGLASIALSA
LFAPVNDAMERRASDIIRNEYPDCTLTLSSRIGRIGLLERENAGIMNASLASLARETVSGFRSALAELGIIAPFYVSQND
GTLMNAEFVEQYPVLTFASGPTNSMRGAAYLSGLKDALVADIGGTTTDIGVLSNGFPRESSVMVDIGGVRTNFRMPDIIA
LGLGGGSIVTPLSDGTVRIGPQSVGYDITTQALVFGGTTLTTTDLAVAAGYADIGDRSRVAGLDSQLVERGITEIHRLVE
TGVDRMKTSGDAAPLILVGGGAILINREIRGVSDMRTHRDAGVANAIGASIAQIGGETDKVYAYDTDGRDAAMADAISSA
RARAVAAGADAASIEIMDIEELPLAYIPGGAVRLRVKVAGNLAAAGAD
>Mature_528_residues
MQRISEKKPLRIGVDVGGTNTDAVLMQGERVLASTKSPTTRSVRDGIVSAISAVIGSAGAAVSDISVVSIGTTHFTNAFV
QRRGLDRVGVIRIALPAAQALPPMTDWPEDIASAIGGQTYAVRGGYQYDGRINADLDELAVADAARKLRAEGLASIALSA
LFAPVNDAMERRASDIIRNEYPDCTLTLSSRIGRIGLLERENAGIMNASLASLARETVSGFRSALAELGIIAPFYVSQND
GTLMNAEFVEQYPVLTFASGPTNSMRGAAYLSGLKDALVADIGGTTTDIGVLSNGFPRESSVMVDIGGVRTNFRMPDIIA
LGLGGGSIVTPLSDGTVRIGPQSVGYDITTQALVFGGTTLTTTDLAVAAGYADIGDRSRVAGLDSQLVERGITEIHRLVE
TGVDRMKTSGDAAPLILVGGGAILINREIRGVSDMRTHRDAGVANAIGASIAQIGGETDKVYAYDTDGRDAAMADAISSA
RARAVAAGADAASIEIMDIEELPLAYIPGGAVRLRVKVAGNLAAAGAD

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 54723; Mature: 54723

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRISEKKPLRIGVDVGGTNTDAVLMQGERVLASTKSPTTRSVRDGIVSAISAVIGSAGA
CCCCCCCCCEEEEEEECCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
AVSDISVVSIGTTHFTNAFVQRRGLDRVGVIRIALPAAQALPPMTDWPEDIASAIGGQTY
CCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEEECHHHHCCCCCCCHHHHHHHHCCCEE
AVRGGYQYDGRINADLDELAVADAARKLRAEGLASIALSALFAPVNDAMERRASDIIRNE
EEECCEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPDCTLTLSSRIGRIGLLERENAGIMNASLASLARETVSGFRSALAELGIIAPFYVSQND
CCCEEEEHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GTLMNAEFVEQYPVLTFASGPTNSMRGAAYLSGLKDALVADIGGTTTDIGVLSNGFPRES
CCEECHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCC
SVMVDIGGVRTNFRMPDIIALGLGGGSIVTPLSDGTVRIGPQSVGYDITTQALVFGGTTL
CEEEEECCCEECCCCCCEEEEECCCCCEEEECCCCEEEECCHHCCCCEEEEEEEECCCEE
TTTDLAVAAGYADIGDRSRVAGLDSQLVERGITEIHRLVETGVDRMKTSGDAAPLILVGG
EEHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
GAILINREIRGVSDMRTHRDAGVANAIGASIAQIGGETDKVYAYDTDGRDAAMADAISSA
CEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
RARAVAAGADAASIEIMDIEELPLAYIPGGAVRLRVKVAGNLAAAGAD
HHHHEECCCCCCEEEEEECCCCCEEEECCCEEEEEEEEECCEECCCCC
>Mature Secondary Structure
MQRISEKKPLRIGVDVGGTNTDAVLMQGERVLASTKSPTTRSVRDGIVSAISAVIGSAGA
CCCCCCCCCEEEEEEECCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
AVSDISVVSIGTTHFTNAFVQRRGLDRVGVIRIALPAAQALPPMTDWPEDIASAIGGQTY
CCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEEECHHHHCCCCCCCHHHHHHHHCCCEE
AVRGGYQYDGRINADLDELAVADAARKLRAEGLASIALSALFAPVNDAMERRASDIIRNE
EEECCEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPDCTLTLSSRIGRIGLLERENAGIMNASLASLARETVSGFRSALAELGIIAPFYVSQND
CCCEEEEHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GTLMNAEFVEQYPVLTFASGPTNSMRGAAYLSGLKDALVADIGGTTTDIGVLSNGFPRES
CCEECHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCC
SVMVDIGGVRTNFRMPDIIALGLGGGSIVTPLSDGTVRIGPQSVGYDITTQALVFGGTTL
CEEEEECCCEECCCCCCEEEEECCCCCEEEECCCCEEEECCHHCCCCEEEEEEEECCCEE
TTTDLAVAAGYADIGDRSRVAGLDSQLVERGITEIHRLVETGVDRMKTSGDAAPLILVGG
EEHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
GAILINREIRGVSDMRTHRDAGVANAIGASIAQIGGETDKVYAYDTDGRDAAMADAISSA
CEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
RARAVAAGADAASIEIMDIEELPLAYIPGGAVRLRVKVAGNLAAAGAD
HHHHEECCCCCCEEEEEECCCCCEEEECCCEEEEEEEEECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]