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The map label for this gene is asd [H]

Identifier: 114797625

GI number: 114797625

Start: 49913

End: 50947

Strand: Direct

Name: asd [H]

Synonym: HNE_0061

Alternate gene names: 114797625

Gene position: 49913-50947 (Clockwise)

Preceding gene: 114799115

Following gene: 114798190

Centisome position: 1.35

GC content: 59.42

Gene sequence:

>1035_bases
ATGGGCACACGCATCGCGGTTGTCGGCGCCACAGGTAATGTTGGGCGGGAACTCCTCAACATTCTGGACGAGCGACTCTT
CCCCGCCGACGAAGTTTTCGCAGTCGCTTCGCGCCGGTCGATTGGCAAGGAGGTCTCCTATGGAGACCGGACCCTGAAAT
GCCATGACCTGGAGCAGTTTGACTTCAGCCGCGTCGATGTCGTGCTGATGTCGGCAGGCGGCAAGGTCTCGAAAGAGTGG
TCGCCGAAGATTGCCAAGGCGGGCGCCATCGTTATCGACAACTCGTCGCAATGGCGGATGGACCCGGATGTGCCCTTGGT
GGTCCCGGAAGTGAACGCAGACGCGGTTCTCGGCTATGAGAAGAAGCGGATCATCGCCAATCCGAACTGCTCCACGGCGC
AGCTCGTTGTGGCGCTGAAGCCCATCCATGACGCTGTCGGCATCAAACGGGTCGTCGTGGCGACGTATCAGTCTGTCTCC
GGCGCCGGCAAGGAAGCCATGGACGAGCTGTGGAACCAGACGCGCGGCATTTTCGTCAATGACGAACCCGCCCCGCAGGT
CTTCCAGAAGGAGATCGCCTTCAACGTCATCCCGCAGATCGACGTGTTCATGGACGATGGCTACACCAAGGAAGAGTGGA
AGATGCGCGTCGAGACGAAGAAAATTCTCGATGAAAAGATTGAGCTGGTGGCCACCTGTGTGCGCGTGCCGGTGTTTGTC
GGCCACTCCGAAGCGGTACACATCGAAACCATCGGGCATATGAGCGCGGATGAATGCCGCGCCCTGCTGCGTGAAAGCCC
CGGCCTCATGGTGGTGGATGATCCCAAGGAAGATCTCTTCATCACGCCCAAAGAGTGCGTGGGGGAGTGGGCAACCTATA
TCAGCCGCATCCGTCACGATCCCACCACAGAAAACGGCCTCGCCTTCTGGTGCGTGTCGGACAATCTCCGCAAGGGCGCG
GCTCTGAACGCGGTCCAGATCGCTGAGGAATTGCTCAATCGCGGCATCATCAAACCGGAGAAAGTCCACGCTTAG

Upstream 100 bases:

>100_bases
CGGCGCAGTCCTGCCTGACGCGGCTGAATTGCACAAGCCGCTTTAAGATGGGCGCGAGATGGGCCATATAGCCCGCCAAC
ATGAACCAGAGGAGATAAAA

Downstream 100 bases:

>100_bases
GCGCGGGCTGTCCTGAGGGACGAATTGAACATCCCGGCCACGCCCTGCGTTGCCGGGATGTTCGTTTCTAGAGCTCTGAA
AAGTCCACCACTTCAAAGCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGTRIAVVGATGNVGRELLNILDERLFPADEVFAVASRRSIGKEVSYGDRTLKCHDLEQFDFSRVDVVLMSAGGKVSKEW
SPKIAKAGAIVIDNSSQWRMDPDVPLVVPEVNADAVLGYEKKRIIANPNCSTAQLVVALKPIHDAVGIKRVVVATYQSVS
GAGKEAMDELWNQTRGIFVNDEPAPQVFQKEIAFNVIPQIDVFMDDGYTKEEWKMRVETKKILDEKIELVATCVRVPVFV
GHSEAVHIETIGHMSADECRALLRESPGLMVVDDPKEDLFITPKECVGEWATYISRIRHDPTTENGLAFWCVSDNLRKGA
ALNAVQIAEELLNRGIIKPEKVHA

Sequences:

>Translated_344_residues
MGTRIAVVGATGNVGRELLNILDERLFPADEVFAVASRRSIGKEVSYGDRTLKCHDLEQFDFSRVDVVLMSAGGKVSKEW
SPKIAKAGAIVIDNSSQWRMDPDVPLVVPEVNADAVLGYEKKRIIANPNCSTAQLVVALKPIHDAVGIKRVVVATYQSVS
GAGKEAMDELWNQTRGIFVNDEPAPQVFQKEIAFNVIPQIDVFMDDGYTKEEWKMRVETKKILDEKIELVATCVRVPVFV
GHSEAVHIETIGHMSADECRALLRESPGLMVVDDPKEDLFITPKECVGEWATYISRIRHDPTTENGLAFWCVSDNLRKGA
ALNAVQIAEELLNRGIIKPEKVHA
>Mature_343_residues
GTRIAVVGATGNVGRELLNILDERLFPADEVFAVASRRSIGKEVSYGDRTLKCHDLEQFDFSRVDVVLMSAGGKVSKEWS
PKIAKAGAIVIDNSSQWRMDPDVPLVVPEVNADAVLGYEKKRIIANPNCSTAQLVVALKPIHDAVGIKRVVVATYQSVSG
AGKEAMDELWNQTRGIFVNDEPAPQVFQKEIAFNVIPQIDVFMDDGYTKEEWKMRVETKKILDEKIELVATCVRVPVFVG
HSEAVHIETIGHMSADECRALLRESPGLMVVDDPKEDLFITPKECVGEWATYISRIRHDPTTENGLAFWCVSDNLRKGAA
LNAVQIAEELLNRGIIKPEKVHA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=342, Percent_Identity=35.3801169590643, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=27.887323943662, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=400, Percent_Identity=28.75, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38077; Mature: 37946

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTRIAVVGATGNVGRELLNILDERLFPADEVFAVASRRSIGKEVSYGDRTLKCHDLEQF
CCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCC
DFSRVDVVLMSAGGKVSKEWSPKIAKAGAIVIDNSSQWRMDPDVPLVVPEVNADAVLGYE
CCCCEEEEEEECCCCCCCCCCCCHHHCCEEEEECCCCEEECCCCCEEEECCCCCEEECCC
KKRIIANPNCSTAQLVVALKPIHDAVGIKRVVVATYQSVSGAGKEAMDELWNQTRGIFVN
CCEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEC
DEPAPQVFQKEIAFNVIPQIDVFMDDGYTKEEWKMRVETKKILDEKIELVATCVRVPVFV
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
GHSEAVHIETIGHMSADECRALLRESPGLMVVDDPKEDLFITPKECVGEWATYISRIRHD
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHCC
PTTENGLAFWCVSDNLRKGAALNAVQIAEELLNRGIIKPEKVHA
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure 
GTRIAVVGATGNVGRELLNILDERLFPADEVFAVASRRSIGKEVSYGDRTLKCHDLEQF
CCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCC
DFSRVDVVLMSAGGKVSKEWSPKIAKAGAIVIDNSSQWRMDPDVPLVVPEVNADAVLGYE
CCCCEEEEEEECCCCCCCCCCCCHHHCCEEEEECCCCEEECCCCCEEEECCCCCEEECCC
KKRIIANPNCSTAQLVVALKPIHDAVGIKRVVVATYQSVSGAGKEAMDELWNQTRGIFVN
CCEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEC
DEPAPQVFQKEIAFNVIPQIDVFMDDGYTKEEWKMRVETKKILDEKIELVATCVRVPVFV
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
GHSEAVHIETIGHMSADECRALLRESPGLMVVDDPKEDLFITPKECVGEWATYISRIRHD
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHCC
PTTENGLAFWCVSDNLRKGAALNAVQIAEELLNRGIIKPEKVHA
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]