BacMap

Definition	Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession	NC_008358
Length	3,705,021

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The map label for this gene is crt [H]

Identifier: 114797602

GI number: 114797602

Start: 2910171

End: 2910959

Strand: Reverse

Name: crt [H]

Synonym: HNE_2749

Alternate gene names: 114797602

Gene position: 2910959-2910171 (Counterclockwise)

Preceding gene: 114797526

Following gene: 114799956

Centisome position: 78.57

GC content: 64.39

Gene sequence:

>789_bases
ATGACAGCACACCATATCAAACTGACCAAAGAGGAAGACGGCATCGCCATCCTCACCATCGACCGGCCGGAGAAGCGCGG
GGCGATGACCTATCTGATGCTGCACACCTTCATCGACGCCGTGCGTGAAGTGGGCAAGGATGACAGCGTCCGTGTGCTGA
TCGTGACCGGGTCGGGCGGCAGCTTCTGCGCTGGCACGGACCTTTCCGATCTCTCCACCATTCCCGGCGAAACCCGCAGC
GTGCGCGGGGAAGCCCATCAGGACGACATCTGGTGGCCGCTGGTGTCCTGTCCGAAGCCGGTGATCGGCGCGATTGATGG
CTATGCCGTCGGCATGGGCGCTGAATTCACAAGCCAGTGCGATGTGCGCATCATCACGCCGCGCACGCGCTTTGCCTGGA
ACTTTGCCCATCGCGGCCTGGTGCCCGATACCGGGGCGGGCAGCTGGCTGCTGCCGCGCATCATCGGGCCGAGCCGGGCG
CTGCGGCTCTTGTATTCCGGCGGTTTCCTGGAGGCGGATGAAGCGCTCGCCATCGGCTATGCCAATGCCGTGGCTGAGCC
AGAAGCGCTGCTGGACGCCGCCCGCGCCGAAGCGCGCCGCTATCTCACCTCCTCGCCGTTCTCCATCCGCCGGATGAAGG
AGCTGGTGTGGAAGGGCCTTGAGCGTGACGTTGCCGATCACATGCAGGCCCATGTCACCGCGCTGTCCGCCTGCTTCAAA
TCGGCCGATCACAAGGAAGGGGTTGCCTCCTTCCTCGAGAAACGCCCGGCGAAGTTTACGGGCACCTGA

Upstream 100 bases:

>100_bases
TCCACGCGGCTATCTCTACTTCGCCATCGCCTTCTCGCTGGGGGTAGAGCTGCTCAATATCCGGGCCAGCCGGAACGCCG
CAAAACCGGGAGGACATTGA

Downstream 100 bases:

>100_bases
TGACGGACGACATGGTGGTGATCCCTCTGCCGGTTGAGACGGGCGGCGTGACGTTTGCCGTTGCCCGCCTCATATCGGTC
GAGGGAGAACCGTTTGCCGA

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTAHHIKLTKEEDGIAILTIDRPEKRGAMTYLMLHTFIDAVREVGKDDSVRVLIVTGSGGSFCAGTDLSDLSTIPGETRS
VRGEAHQDDIWWPLVSCPKPVIGAIDGYAVGMGAEFTSQCDVRIITPRTRFAWNFAHRGLVPDTGAGSWLLPRIIGPSRA
LRLLYSGGFLEADEALAIGYANAVAEPEALLDAARAEARRYLTSSPFSIRRMKELVWKGLERDVADHMQAHVTALSACFK
SADHKEGVASFLEKRPAKFTGT

Sequences:

>Translated_262_residues
MTAHHIKLTKEEDGIAILTIDRPEKRGAMTYLMLHTFIDAVREVGKDDSVRVLIVTGSGGSFCAGTDLSDLSTIPGETRS
VRGEAHQDDIWWPLVSCPKPVIGAIDGYAVGMGAEFTSQCDVRIITPRTRFAWNFAHRGLVPDTGAGSWLLPRIIGPSRA
LRLLYSGGFLEADEALAIGYANAVAEPEALLDAARAEARRYLTSSPFSIRRMKELVWKGLERDVADHMQAHVTALSACFK
SADHKEGVASFLEKRPAKFTGT
>Mature_261_residues
TAHHIKLTKEEDGIAILTIDRPEKRGAMTYLMLHTFIDAVREVGKDDSVRVLIVTGSGGSFCAGTDLSDLSTIPGETRSV
RGEAHQDDIWWPLVSCPKPVIGAIDGYAVGMGAEFTSQCDVRIITPRTRFAWNFAHRGLVPDTGAGSWLLPRIIGPSRAL
RLLYSGGFLEADEALAIGYANAVAEPEALLDAARAEARRYLTSSPFSIRRMKELVWKGLERDVADHMQAHVTALSACFKS
ADHKEGVASFLEKRPAKFTGT

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=25.6, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI213417737, Length=247, Percent_Identity=26.7206477732794, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI157694516, Length=247, Percent_Identity=26.7206477732794, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI260274832, Length=248, Percent_Identity=27.0161290322581, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI45643119, Length=248, Percent_Identity=27.0161290322581, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI260275230, Length=248, Percent_Identity=27.0161290322581, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4502327, Length=264, Percent_Identity=29.5454545454545, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI70995211, Length=265, Percent_Identity=25.6603773584906, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI31542718, Length=248, Percent_Identity=25, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI150378541, Length=259, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI157694520, Length=220, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI25453481, Length=256, Percent_Identity=21.484375, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI51538573, Length=256, Percent_Identity=21.484375, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI116235487, Length=253, Percent_Identity=25.296442687747, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI37594469, Length=279, Percent_Identity=24.3727598566308, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI37594471, Length=276, Percent_Identity=22.8260869565217, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI68989263, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4757966, Length=250, Percent_Identity=22, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI51538581, Length=250, Percent_Identity=22, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221136756, Length=257, Percent_Identity=21.7898832684825, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI221136753, Length=257, Percent_Identity=21.7898832684825, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4757968, Length=256, Percent_Identity=21.09375, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI49355787, Length=256, Percent_Identity=21.09375, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI221307494, Length=257, Percent_Identity=21.7898832684825, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20127408, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=257, Percent_Identity=33.4630350194552, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=26.6409266409266, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=27.7992277992278, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=30.0395256916996, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790281, Length=195, Percent_Identity=28.7179487179487, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788682, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=25, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=260, Percent_Identity=27.3076923076923, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=26.984126984127, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=261, Percent_Identity=25.2873563218391, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=275, Percent_Identity=25.4545454545455, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=260, Percent_Identity=26.1538461538462, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25141363, Length=171, Percent_Identity=30.9941520467836, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=245, Percent_Identity=24.0816326530612, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=189, Percent_Identity=24.8677248677249, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=29.7619047619048, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=29.7619047619048, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=28.6792452830189, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357171, Length=184, Percent_Identity=33.1521739130435, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24654903, Length=249, Percent_Identity=24.4979919678715, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI19922422, Length=256, Percent_Identity=25, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650670, Length=182, Percent_Identity=27.4725274725275, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920382, Length=250, Percent_Identity=26.8, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28582; Mature: 28451

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHHIKLTKEEDGIAILTIDRPEKRGAMTYLMLHTFIDAVREVGKDDSVRVLIVTGSGG
CCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SFCAGTDLSDLSTIPGETRSVRGEAHQDDIWWPLVSCPKPVIGAIDGYAVGMGAEFTSQC
CEECCCCHHHHHCCCCCCHHCCCCCCCCCCCCHHHCCCCHHHHCCCCEEECCCCCCCCCC
DVRIITPRTRFAWNFAHRGLVPDTGAGSWLLPRIIGPSRALRLLYSGGFLEADEALAIGY
CEEEECCCCCEEEHHHHCCCCCCCCCCCEEHHHHCCHHHHHHHHHCCCCCCCCCEEEEEH
ANAVAEPEALLDAARAEARRYLTSSPFSIRRMKELVWKGLERDVADHMQAHVTALSACFK
HHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SADHKEGVASFLEKRPAKFTGT
CCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAHHIKLTKEEDGIAILTIDRPEKRGAMTYLMLHTFIDAVREVGKDDSVRVLIVTGSGG
CCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
SFCAGTDLSDLSTIPGETRSVRGEAHQDDIWWPLVSCPKPVIGAIDGYAVGMGAEFTSQC
CEECCCCHHHHHCCCCCCHHCCCCCCCCCCCCHHHCCCCHHHHCCCCEEECCCCCCCCCC
DVRIITPRTRFAWNFAHRGLVPDTGAGSWLLPRIIGPSRALRLLYSGGFLEADEALAIGY
CEEEECCCCCEEEHHHHCCCCCCCCCCCEEHHHHCCHHHHHHHHHCCCCCCCCCEEEEEH
ANAVAEPEALLDAARAEARRYLTSSPFSIRRMKELVWKGLERDVADHMQAHVTALSACFK
HHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SADHKEGVASFLEKRPAKFTGT
CCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]