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The map label for this gene is icfA [H]

Identifier: 114797544

GI number: 114797544

Start: 10429

End: 11052

Strand: Direct

Name: icfA [H]

Synonym: HNE_0015

Alternate gene names: 114797544

Gene position: 10429-11052 (Clockwise)

Preceding gene: 114798262

Following gene: 114799979

Centisome position: 0.28

GC content: 61.7

Gene sequence:

>624_bases
ATGAAAACTGTCGATGACATGATCACCGGCTACCGTCGCTTCCGGTCCGGCGTGTATGCCGAACAGGTAGAGCTTTACCG
TCAGCTCGGAGAGGGGCAGGACCCCGACATCATGCTGATCGGGTGTGCTGACAGCCGGGCGGAGCCTTCGGATATTTTCA
ACGCCGCGCCGGGACAGATGTTCGTGGTGCGTAACGTCGCCAATCTGGTGCCGCCCTACCAGCCCAATGGCGGGCTGCAC
GGCGTCTCCGCCGCCCTCGAATTTGCGGTGAACATTCTCAAGGTAAAGATCATCGTGGTCATGGGCCATGGTGGCTGTGG
CGGGATCTCCGCCTCACTCACCAAGAATGACAGCCCGCTGATCGGCGAATTCGTCGCCCCTTGGGTGAAGTTGCTGGACG
AGGCGCGCGAGCGGGTTCTGGCGACCCAGCCGGTAAACCCGCAATTTGCGCTGGAGCTGGAAGGCATCGAAACCTCGATC
CAGAACCTCATGACCTTCCCCTTCGTCCGCGAGAAGGTCGAGGCGGGCACGCTGGAAATCCACGGCGCCTGGTTTGCCAT
CAAGCATGGCGAGCTCCACTGGCGCAATCCGCGCTCCCAGCGGTTCGAAATCGTGGCGCCCTAG

Upstream 100 bases:

>100_bases
CGAGACTGACCGTTCCGTGTTAACGAGGATTCGTTTCAAATTTGCTTGCACCGCAGCAATTTTTGCGCGATCCGCCCCTC
CGCAAGCTTGGAGAACTGGG

Downstream 100 bases:

>100_bases
AAACAGAACTGGCCTGGAAGGGTGCACCCTCCAGGCCAGCTTCGGTCATCTTTGGACAAATCCCGACAGATCAGCCCTTC
AGGTTTGCCTGCTCGCGGGC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKTVDDMITGYRRFRSGVYAEQVELYRQLGEGQDPDIMLIGCADSRAEPSDIFNAAPGQMFVVRNVANLVPPYQPNGGLH
GVSAALEFAVNILKVKIIVVMGHGGCGGISASLTKNDSPLIGEFVAPWVKLLDEARERVLATQPVNPQFALELEGIETSI
QNLMTFPFVREKVEAGTLEIHGAWFAIKHGELHWRNPRSQRFEIVAP

Sequences:

>Translated_207_residues
MKTVDDMITGYRRFRSGVYAEQVELYRQLGEGQDPDIMLIGCADSRAEPSDIFNAAPGQMFVVRNVANLVPPYQPNGGLH
GVSAALEFAVNILKVKIIVVMGHGGCGGISASLTKNDSPLIGEFVAPWVKLLDEARERVLATQPVNPQFALELEGIETSI
QNLMTFPFVREKVEAGTLEIHGAWFAIKHGELHWRNPRSQRFEIVAP
>Mature_207_residues
MKTVDDMITGYRRFRSGVYAEQVELYRQLGEGQDPDIMLIGCADSRAEPSDIFNAAPGQMFVVRNVANLVPPYQPNGGLH
GVSAALEFAVNILKVKIIVVMGHGGCGGISASLTKNDSPLIGEFVAPWVKLLDEARERVLATQPVNPQFALELEGIETSI
QNLMTFPFVREKVEAGTLEIHGAWFAIKHGELHWRNPRSQRFEIVAP

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=196, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786318, Length=125, Percent_Identity=32, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147564, Length=238, Percent_Identity=27.3109243697479, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115532990, Length=242, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=172, Percent_Identity=28.4883720930233, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 22828; Mature: 22828

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVDDMITGYRRFRSGVYAEQVELYRQLGEGQDPDIMLIGCADSRAEPSDIFNAAPGQM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVVRNVANLVPPYQPNGGLHGVSAALEFAVNILKVKIIVVMGHGGCGGISASLTKNDSPL
EEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCC
IGEFVAPWVKLLDEARERVLATQPVNPQFALELEGIETSIQNLMTFPFVREKVEAGTLEI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEE
HGAWFAIKHGELHWRNPRSQRFEIVAP
EEEEEEEECCEEEECCCCCCCEEEECC
>Mature Secondary Structure
MKTVDDMITGYRRFRSGVYAEQVELYRQLGEGQDPDIMLIGCADSRAEPSDIFNAAPGQM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVVRNVANLVPPYQPNGGLHGVSAALEFAVNILKVKIIVVMGHGGCGGISASLTKNDSPL
EEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCC
IGEFVAPWVKLLDEARERVLATQPVNPQFALELEGIETSIQNLMTFPFVREKVEAGTLEI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEE
HGAWFAIKHGELHWRNPRSQRFEIVAP
EEEEEEEECCEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]