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The map label for this gene is gst [C]

Identifier: 114797468

GI number: 114797468

Start: 1026338

End: 1026997

Strand: Direct

Name: gst [C]

Synonym: HNE_1014

Alternate gene names: 114797468

Gene position: 1026338-1026997 (Clockwise)

Preceding gene: 114800242

Following gene: 114798076

Centisome position: 27.7

GC content: 62.58

Gene sequence:

>660_bases
ATGCGGGAAGTGACGGCGTATAACTGGGTGCCGGATTTTGCGCAGGGGTTTGTAAAGGATCTGCGCGTGCGCTGGGCTCT
GGAAGAGGCGGGCCTCACCTATACGGAGCGCCTGATCGACCATGAGCAGAAGCTGCAGCCCGAACACATGGCGCGCCAGC
CTTTTGCGCAGGTGCCGGTTTACAAGGATGACGGGGTGGAGATGTTCGAATCCGCCGCCATCGTGCTGCATATCGCGCAG
GGGTCCGACGCGCTCATGCCGAAAGACGCTGCGGCGCGGGCGCGGGTGACGAGCTGGTGCTTTGCGGCGCTCAACTCCAT
TGAGCCTTACGTGATGAATGTAACGGGCACGCAGCTTTTCCATGCAGATGCGCCGTGGGCGGAGGGGTATCTGGCAAGCG
CGCGCGGCATGCTCGACATGCGCCTGAACCAGCTTTCAGGCTGGCTGAAAGGGCAGGACTATCTGGAAGCCGGGCGGTTT
ACAGCCGCGGATCTCCTGATGGCCAGTGTTCTGCGGGAACTGGAACGGGATGGAACGCTCGGGCATTTTCCGGAGCTGGA
GGCGTATTGTCAGCAGTGTCTTTCCCGTCCCGCATTCAGGCGGGCGCTGGAGGCGCAGCTCGCCGTTTTCGCCAAAGCCG
AAGTGCCGGCTGGCGTCTGA

Upstream 100 bases:

>100_bases
TTTTGGTCAAGGAAAAACATGCACAGCCCGCCGGAGAGGCGGGGTTGAGCCATGGATAAGGCAGGCGCGCAGCGCCGCTG
ATGAGTGATGGAGGACCGCG

Downstream 100 bases:

>100_bases
GGAGGCAGCATATGACGAAGTATCTGATTTCATTTCCGAGTGAAGCCATGGTGGTCGCCGAAGACGACTTTCCAGCGGTC
GTTGCTGACTCCCATGCGGT

Product: glutathione S-transferase

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Protein; Glutathione S-Transferase Domain; Glutathione S-Transferase-Like; Glutatione S-Transferase; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase C-Terminal Domain Protein; Glutathione S-Transferase I; Glutathione-S-Transferase; Transcriptional Regulator; Gst14 Glutatione S-Transferase; Glutathione S-Transferase Family Protein; Glutathione S Transferase; Glutathione Transferase

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MREVTAYNWVPDFAQGFVKDLRVRWALEEAGLTYTERLIDHEQKLQPEHMARQPFAQVPVYKDDGVEMFESAAIVLHIAQ
GSDALMPKDAAARARVTSWCFAALNSIEPYVMNVTGTQLFHADAPWAEGYLASARGMLDMRLNQLSGWLKGQDYLEAGRF
TAADLLMASVLRELERDGTLGHFPELEAYCQQCLSRPAFRRALEAQLAVFAKAEVPAGV

Sequences:

>Translated_219_residues
MREVTAYNWVPDFAQGFVKDLRVRWALEEAGLTYTERLIDHEQKLQPEHMARQPFAQVPVYKDDGVEMFESAAIVLHIAQ
GSDALMPKDAAARARVTSWCFAALNSIEPYVMNVTGTQLFHADAPWAEGYLASARGMLDMRLNQLSGWLKGQDYLEAGRF
TAADLLMASVLRELERDGTLGHFPELEAYCQQCLSRPAFRRALEAQLAVFAKAEVPAGV
>Mature_219_residues
MREVTAYNWVPDFAQGFVKDLRVRWALEEAGLTYTERLIDHEQKLQPEHMARQPFAQVPVYKDDGVEMFESAAIVLHIAQ
GSDALMPKDAAARARVTSWCFAALNSIEPYVMNVTGTQLFHADAPWAEGYLASARGMLDMRLNQLSGWLKGQDYLEAGRF
TAADLLMASVLRELERDGTLGHFPELEAYCQQCLSRPAFRRALEAQLAVFAKAEVPAGV

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 24509; Mature: 24509

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVTAYNWVPDFAQGFVKDLRVRWALEEAGLTYTERLIDHEQKLQPEHMARQPFAQVPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHCCHHHCCC
YKDDGVEMFESAAIVLHIAQGSDALMPKDAAARARVTSWCFAALNSIEPYVMNVTGTQLF
CCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEE
HADAPWAEGYLASARGMLDMRLNQLSGWLKGQDYLEAGRFTAADLLMASVLRELERDGTL
ECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
GHFPELEAYCQQCLSRPAFRRALEAQLAVFAKAEVPAGV
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREVTAYNWVPDFAQGFVKDLRVRWALEEAGLTYTERLIDHEQKLQPEHMARQPFAQVPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHCCHHHCCC
YKDDGVEMFESAAIVLHIAQGSDALMPKDAAARARVTSWCFAALNSIEPYVMNVTGTQLF
CCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEE
HADAPWAEGYLASARGMLDMRLNQLSGWLKGQDYLEAGRFTAADLLMASVLRELERDGTL
ECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
GHFPELEAYCQQCLSRPAFRRALEAQLAVFAKAEVPAGV
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA