Click here to switch to the map view.

The map label for this gene is ppi [H]

Identifier: 114797409

GI number: 114797409

Start: 366022

End: 366948

Strand: Reverse

Name: ppi [H]

Synonym: HNE_0375

Alternate gene names: 114797409

Gene position: 366948-366022 (Counterclockwise)

Preceding gene: 114797658

Following gene: 114800371

Centisome position: 9.9

GC content: 65.16

Gene sequence:

>927_bases
ATGAAACGCGCCCTGTCTTTCGCCGCTGCCCTCGTCTGTGCTGCCAGCGCCGCCGCGCCGCCCGGATTGTCCGAAACTGT
CCCGGCGGTGACCCCGCCTGTCCAGGATTGGCGCGCGGTTGACCCGGAAAATCTCGTCCTTGTCACGCTGGAGACCGGCA
CCGTCGCCATCGAGCTTTACCCAGAAGCCGCCCCGGCGCATGCCGCGCAGATCCGCGAAGCGGTGCGCGAAGGCTTCTAT
GACGGGGAATATTTCTACCGCGTCGTCGAAGGCCATGTTGCCCAGGCTGGCCGGGAGTTTCCGATGTCCGTTGCCGCCTG
GCCCACCCTGCCCTTCGAAGCCGAACGCGAGATCCCCGCAGACGGCTTTGTGCCCCAGGGCAATGGCGATCTCTATGCCG
CTGAAGTGGGCCACCGCGACGGCTTTGCCGTCGGCCGCGAGGGCGGCAGGGAATGGCTGCTCAACTGCCCCGGCGCCCTC
GGCATGGCCCGCGACAACAACCCCGAAAGCGGCTCCACCGAAATCTTCGTCCCCCTCCAGCCCCGGCGCTATCTGGACCG
CAACTACACCGTTTTCGGGCGGGTGATCGATGGCATGGAATTCATTCACCGCCTGCCCCGCGTTGATCCGTCAACAGAAG
AAGAGATGAACGCCCTGTTTGGCGAAGACACCGAACTCGCCCATCAGATCAGCCAGTATCGCCGCTCGAAACTCGCAGAA
AACCAGATCCGCTCTGCCCGCATGGCCGCCGATATTCCGGTGGAGAACCGCCCGGCCTATGATGTGATGCAGACGCCCTC
TGCCACATGGGACGCCCTCAAGGAGTCCAAGCGCGACTATTCCGGCATCGCCGCGCTCGCCTATGTCCCGCCCAAGGTGC
TGGACATCTGCGCCCTTCCCGTGCCTGCCCGCCGCGTGGGCGAATAG

Upstream 100 bases:

>100_bases
AGGCGAAACGAAGCCGATCTGCGCGCCGTGATTGCAGCGGGGATGTTTACGCCGGCCGCCGGCATTGACGCGCGCCCTGC
CCTCGCAGACAGTTGCCGGC

Downstream 100 bases:

>100_bases
GCGGCGCGGAAACAGGCATTTGCCAACCTTACGCAATTATAATCTGCCTCGAATCCATCGCGAAACAGCGCACTAGCGCC
GCCGCTTCCGCGCGGGCCGC

Product: cyclophilin-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKRALSFAAALVCAASAAAPPGLSETVPAVTPPVQDWRAVDPENLVLVTLETGTVAIELYPEAAPAHAAQIREAVREGFY
DGEYFYRVVEGHVAQAGREFPMSVAAWPTLPFEAEREIPADGFVPQGNGDLYAAEVGHRDGFAVGREGGREWLLNCPGAL
GMARDNNPESGSTEIFVPLQPRRYLDRNYTVFGRVIDGMEFIHRLPRVDPSTEEEMNALFGEDTELAHQISQYRRSKLAE
NQIRSARMAADIPVENRPAYDVMQTPSATWDALKESKRDYSGIAALAYVPPKVLDICALPVPARRVGE

Sequences:

>Translated_308_residues
MKRALSFAAALVCAASAAAPPGLSETVPAVTPPVQDWRAVDPENLVLVTLETGTVAIELYPEAAPAHAAQIREAVREGFY
DGEYFYRVVEGHVAQAGREFPMSVAAWPTLPFEAEREIPADGFVPQGNGDLYAAEVGHRDGFAVGREGGREWLLNCPGAL
GMARDNNPESGSTEIFVPLQPRRYLDRNYTVFGRVIDGMEFIHRLPRVDPSTEEEMNALFGEDTELAHQISQYRRSKLAE
NQIRSARMAADIPVENRPAYDVMQTPSATWDALKESKRDYSGIAALAYVPPKVLDICALPVPARRVGE
>Mature_308_residues
MKRALSFAAALVCAASAAAPPGLSETVPAVTPPVQDWRAVDPENLVLVTLETGTVAIELYPEAAPAHAAQIREAVREGFY
DGEYFYRVVEGHVAQAGREFPMSVAAWPTLPFEAEREIPADGFVPQGNGDLYAAEVGHRDGFAVGREGGREWLLNCPGAL
GMARDNNPESGSTEIFVPLQPRRYLDRNYTVFGRVIDGMEFIHRLPRVDPSTEEEMNALFGEDTELAHQISQYRRSKLAE
NQIRSARMAADIPVENRPAYDVMQTPSATWDALKESKRDYSGIAALAYVPPKVLDICALPVPARRVGE

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33766; Mature: 33766

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRALSFAAALVCAASAAAPPGLSETVPAVTPPVQDWRAVDPENLVLVTLETGTVAIELY
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEECCEEEEEEC
PEAAPAHAAQIREAVREGFYDGEYFYRVVEGHVAQAGREFPMSVAAWPTLPFEAEREIPA
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCC
DGFVPQGNGDLYAAEVGHRDGFAVGREGGREWLLNCPGALGMARDNNPESGSTEIFVPLQ
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECC
PRRYLDRNYTVFGRVIDGMEFIHRLPRVDPSTEEEMNALFGEDTELAHQISQYRRSKLAE
CHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NQIRSARMAADIPVENRPAYDVMQTPSATWDALKESKRDYSGIAALAYVPPKVLDICALP
HHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCC
VPARRVGE
CCHHHCCC
>Mature Secondary Structure
MKRALSFAAALVCAASAAAPPGLSETVPAVTPPVQDWRAVDPENLVLVTLETGTVAIELY
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEECCEEEEEEC
PEAAPAHAAQIREAVREGFYDGEYFYRVVEGHVAQAGREFPMSVAAWPTLPFEAEREIPA
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCC
DGFVPQGNGDLYAAEVGHRDGFAVGREGGREWLLNCPGALGMARDNNPESGSTEIFVPLQ
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECC
PRRYLDRNYTVFGRVIDGMEFIHRLPRVDPSTEEEMNALFGEDTELAHQISQYRRSKLAE
CHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NQIRSARMAADIPVENRPAYDVMQTPSATWDALKESKRDYSGIAALAYVPPKVLDICALP
HHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCC
VPARRVGE
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA