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The map label for this gene is yccK [H]

Identifier: 114797195

GI number: 114797195

Start: 2326743

End: 2327714

Strand: Reverse

Name: yccK [H]

Synonym: HNE_2225

Alternate gene names: 114797195

Gene position: 2327714-2326743 (Counterclockwise)

Preceding gene: 114797318

Following gene: 114798404

Centisome position: 62.83

GC content: 60.39

Gene sequence:

>972_bases
ATGCATACCCGCAAACTCGGCAGGAATGGACCTGATGTTTCAGCCATTGGCTATGGTGCGATGGGCTTTCATGCCCATTA
TGGCGCGGCCGACCCGCAAGCCGGTCTCGACCTCATCCGGCGCGCCTATGATCAGGGCGTAAATTTCTTCGACACGGCAG
AAATGTATGGCTGGGGCGAGAACGAAAAGTTCATCGGCCAGGCGGTGAAGGGCTTTCGCGATGAGGTCGTGCTGGCCACA
AAATTCGGCTTCACCTATGAAGACGGCGTCTATGGCACCAACAGCCAGCCCGGCCACATCCGCAAAGTAACGGAGAACAG
CCTGCGCCATCTCGGCGTCGACCATATCGACATCCTCTATCAGCACCGCGTCGATCCCGATGTCCCGATCGAAGACGTTG
CCGGGACCATCCGGGATCTGATCGCCGAGGGCAAGGTAAAGTATTTTGGCCTCAGCGAAGCCGGGCCGCAGACGATCCGC
AAGGCCCATGCCGTGCAGCCCGTCACCGTCCTGCAGACCGAATATTCCGTATTCGAACGCAATGTTGAAACGGTTCTGCC
CACCCTACGGGAACTGGGCATCGGCTTTGTCGCTTATTCGCCGCTGGGCCGGGGTTTTCTTACAAGCGCCGTCAAACCGT
CTGCGGAGTATGAAGACACCGATATGCGCCGCTTCGACCCCCGCTGGCAGCCGGGTAATTTCGAGAAGAACCTTGACGCG
GTCCGCCAGCTCGGTGAGCTGGCTAAGGACAAGGGCATCACGGTGTCTCAACTGGCGCTCGCCTGGCTGCTCGCCCAGGG
CGAGGACATCGTTCCGATCCCGGGCACCCGCCGGATCGACCGGCTTGAGGAAAACCTCGCTTCGGCAGAGGTGACGCTGT
CGACTGATGATCTTGCCGGTATCCGGAACATCCTTCCGGAGGGCGCGTTCGGCGCGCGCTATGCCGGCGATATGGTTCCG
GACTGGCTCTGA

Upstream 100 bases:

>100_bases
GCATCCGGCAGGATCAGGCAATCATCCGGGACCATCGGGCATCCATCGGCTGCGCCGTCGGGCTTACATGGACGTTCTCA
ATTCCAGAAAGGACGTCCCG

Downstream 100 bases:

>100_bases
CCGCCACCCCAGACTTCCCCAAGAGCTACAGTGTAGACGGATCTTGTGTTCAGCTCGTCGCGGCGCAACCGTCACGCTTT
CTGGCGCCACTCCGACCTCA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MHTRKLGRNGPDVSAIGYGAMGFHAHYGAADPQAGLDLIRRAYDQGVNFFDTAEMYGWGENEKFIGQAVKGFRDEVVLAT
KFGFTYEDGVYGTNSQPGHIRKVTENSLRHLGVDHIDILYQHRVDPDVPIEDVAGTIRDLIAEGKVKYFGLSEAGPQTIR
KAHAVQPVTVLQTEYSVFERNVETVLPTLRELGIGFVAYSPLGRGFLTSAVKPSAEYEDTDMRRFDPRWQPGNFEKNLDA
VRQLGELAKDKGITVSQLALAWLLAQGEDIVPIPGTRRIDRLEENLASAEVTLSTDDLAGIRNILPEGAFGARYAGDMVP
DWL

Sequences:

>Translated_323_residues
MHTRKLGRNGPDVSAIGYGAMGFHAHYGAADPQAGLDLIRRAYDQGVNFFDTAEMYGWGENEKFIGQAVKGFRDEVVLAT
KFGFTYEDGVYGTNSQPGHIRKVTENSLRHLGVDHIDILYQHRVDPDVPIEDVAGTIRDLIAEGKVKYFGLSEAGPQTIR
KAHAVQPVTVLQTEYSVFERNVETVLPTLRELGIGFVAYSPLGRGFLTSAVKPSAEYEDTDMRRFDPRWQPGNFEKNLDA
VRQLGELAKDKGITVSQLALAWLLAQGEDIVPIPGTRRIDRLEENLASAEVTLSTDDLAGIRNILPEGAFGARYAGDMVP
DWL
>Mature_323_residues
MHTRKLGRNGPDVSAIGYGAMGFHAHYGAADPQAGLDLIRRAYDQGVNFFDTAEMYGWGENEKFIGQAVKGFRDEVVLAT
KFGFTYEDGVYGTNSQPGHIRKVTENSLRHLGVDHIDILYQHRVDPDVPIEDVAGTIRDLIAEGKVKYFGLSEAGPQTIR
KAHAVQPVTVLQTEYSVFERNVETVLPTLRELGIGFVAYSPLGRGFLTSAVKPSAEYEDTDMRRFDPRWQPGNFEKNLDA
VRQLGELAKDKGITVSQLALAWLLAQGEDIVPIPGTRRIDRLEENLASAEVTLSTDDLAGIRNILPEGAFGARYAGDMVP
DWL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=321, Percent_Identity=27.7258566978193, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4504825, Length=318, Percent_Identity=27.6729559748428, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=28.0120481927711, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=28.7037037037037, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=28.7037037037037, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436971, Length=308, Percent_Identity=29.5454545454545, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI223718702, Length=321, Percent_Identity=28.6604361370716, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI41327764, Length=278, Percent_Identity=29.4964028776978, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI41152114, Length=229, Percent_Identity=28.3842794759825, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=29.3939393939394, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=31.8471337579618, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=30.7210031347962, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787674, Length=304, Percent_Identity=26.9736842105263, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788081, Length=320, Percent_Identity=26.25, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=25.7971014492754, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI48994888, Length=280, Percent_Identity=26.4285714285714, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=311, Percent_Identity=27.3311897106109, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325169, Length=329, Percent_Identity=26.1398176291793, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=311, Percent_Identity=25.4019292604502, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=296, Percent_Identity=25, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325384, Length=288, Percent_Identity=28.125, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=267, Percent_Identity=25.8426966292135, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646155, Length=319, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24640980, Length=334, Percent_Identity=25.748502994012, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549126, Length=334, Percent_Identity=25.748502994012, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646159, Length=275, Percent_Identity=23.6363636363636, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35694; Mature: 35694

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTRKLGRNGPDVSAIGYGAMGFHAHYGAADPQAGLDLIRRAYDQGVNFFDTAEMYGWGE
CCCCCCCCCCCCCCEECCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCC
NEKFIGQAVKGFRDEVVLATKFGFTYEDGVYGTNSQPGHIRKVTENSLRHLGVDHIDILY
CHHHHHHHHHHHHHCEEEEEECCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
QHRVDPDVPIEDVAGTIRDLIAEGKVKYFGLSEAGPQTIRKAHAVQPVTVLQTEYSVFER
HHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
NVETVLPTLRELGIGFVAYSPLGRGFLTSAVKPSAEYEDTDMRRFDPRWQPGNFEKNLDA
HHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHH
VRQLGELAKDKGITVSQLALAWLLAQGEDIVPIPGTRRIDRLEENLASAEVTLSTDDLAG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCEEEECCHHHHH
IRNILPEGAFGARYAGDMVPDWL
HHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHTRKLGRNGPDVSAIGYGAMGFHAHYGAADPQAGLDLIRRAYDQGVNFFDTAEMYGWGE
CCCCCCCCCCCCCCEECCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCC
NEKFIGQAVKGFRDEVVLATKFGFTYEDGVYGTNSQPGHIRKVTENSLRHLGVDHIDILY
CHHHHHHHHHHHHHCEEEEEECCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
QHRVDPDVPIEDVAGTIRDLIAEGKVKYFGLSEAGPQTIRKAHAVQPVTVLQTEYSVFER
HHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
NVETVLPTLRELGIGFVAYSPLGRGFLTSAVKPSAEYEDTDMRRFDPRWQPGNFEKNLDA
HHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHH
VRQLGELAKDKGITVSQLALAWLLAQGEDIVPIPGTRRIDRLEENLASAEVTLSTDDLAG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCEEEECCHHHHH
IRNILPEGAFGARYAGDMVPDWL
HHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]