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The map label for this gene is mdtA [H]

Identifier: 114797172

GI number: 114797172

Start: 3232067

End: 3233335

Strand: Direct

Name: mdtA [H]

Synonym: HNE_3060

Alternate gene names: 114797172

Gene position: 3232067-3233335 (Clockwise)

Preceding gene: 114797724

Following gene: 114797926

Centisome position: 87.23

GC content: 65.25

Gene sequence:

>1269_bases
ATGGGACGCCTGATCGCCATCATCGCACCAATTGCCATCCTTCTTGTTCTTGGCGTTGGAGGGGTCATTGCCGTCACGGC
CATGAAGCCTGAGCCGCAGAAGAATGACGAGCCGCAGGCCGGCCTCAATGTCTTTGCCGAACAGGTGAAGTCCGGCTCGC
TGACGATCACCGTGGAAGCGCAGGGCGAAGTCAGCCCGAAGCGCGAGATCATCGTCGCGCCGCAGATTGCCGGACGTGTC
TCCTATGTGTCGCCAGACTTCATCGATGGTGGCTTCATCCGGCGCGGCCAGGTGCTCGTGCGGGTGGAAGCGGCCGATTC
CGAACTGGGCGTCGTGCGCGCCCGGTCGATCGTTGCCACGGCTGAACAGGCCCTCGCCCGCGAGATTGCGGAGGCCGAGC
TTGCCCAGCAGGATCTCGAAAACCTGGGCCTGACAGACGCCTCACCGCTGGCCCGCCGCGAGCCTCAGCTCGCCGAAGCC
CGCGCCGCCCTTGAATCTGCCAAAGCCCAGCTTTCCGAAGCAGAGCTGAGCCTCAGCCGCACGGCCATCATCGCGCCGTT
TGACGGCCGCGTGCGCGAACGTTCTGCCGACATCGGCCAGTTCGTGTCGCCCGGCCAGTCGCTCGGCAATATCTTCGCCA
CTGACGTCGTCGAAGTCGCCCTCCCCCTGAAGGACGCCGACCTTGGCCAGCTCGGCCTGCCAATCGCCTTCTCTTCTTCG
GCAGACGAACCCGGCCCCAAGGTCGAGTTTTCAGCGGTCGTGGGTGGCAAGCCACGCACATGGGTCGGGGAAGTCGTGCG
CACCGGCGCGGCCATCAACTCGCAGACACGTCAGATCAACGTATTCGCCGAACTCAAAGATCCCTTCGGGACCGGCGCCG
ATGACGGCGCGCCAATGGCGCCCGGCCTCTTCGTCACCGCGCGGATCGAAGGCGAGACGCTGGACAACGTCCTGATTGCG
CCGCGCGCGGCCCTGCGGGGGGATGACCGCCTCTTCATTGGCGATCCGAAAGAGGGCAAGCTCTCCATACGGACCGTCGA
TGTCGCCTATTCCGATCGCGACGGCGCCTATCTCCGCTCCGGTGTTGCGCCGGGCGAACTGGCGATCACCAGCCCGATCC
AGGCCGCGTTCGACGGGATGAGCATCACCGTCCTGGAACGCCAGCCCGACGGCACCGTCAAGATCCATGGCGAGAAGAAA
ACCCCGAAAGACGCCGAAGCCATCGCAGACGCCGCCGCAAGTGAAGGCGGCGAAGGGAGCGCTCAATGA

Upstream 100 bases:

>100_bases
ATCATCTCGCCCTGGGCGGCGGCGTTCCCGTGATGGAACTCGCCGGCGAGGACGACCTGTTTGACACTGACGCCGCCGAA
AGCGGCAGGAGATAGACGCC

Downstream 100 bases:

>100_bases
ACGGTCTGGTCGCCTGGTTTACCCGTAACGCGGTCGCCGCCAACCTCCTGATGATCATCGCCTTCGCGGGCGGTGTCTTC
GGGTACAGCGCGATGGAACG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MGRLIAIIAPIAILLVLGVGGVIAVTAMKPEPQKNDEPQAGLNVFAEQVKSGSLTITVEAQGEVSPKREIIVAPQIAGRV
SYVSPDFIDGGFIRRGQVLVRVEAADSELGVVRARSIVATAEQALAREIAEAELAQQDLENLGLTDASPLARREPQLAEA
RAALESAKAQLSEAELSLSRTAIIAPFDGRVRERSADIGQFVSPGQSLGNIFATDVVEVALPLKDADLGQLGLPIAFSSS
ADEPGPKVEFSAVVGGKPRTWVGEVVRTGAAINSQTRQINVFAELKDPFGTGADDGAPMAPGLFVTARIEGETLDNVLIA
PRAALRGDDRLFIGDPKEGKLSIRTVDVAYSDRDGAYLRSGVAPGELAITSPIQAAFDGMSITVLERQPDGTVKIHGEKK
TPKDAEAIADAAASEGGEGSAQ

Sequences:

>Translated_422_residues
MGRLIAIIAPIAILLVLGVGGVIAVTAMKPEPQKNDEPQAGLNVFAEQVKSGSLTITVEAQGEVSPKREIIVAPQIAGRV
SYVSPDFIDGGFIRRGQVLVRVEAADSELGVVRARSIVATAEQALAREIAEAELAQQDLENLGLTDASPLARREPQLAEA
RAALESAKAQLSEAELSLSRTAIIAPFDGRVRERSADIGQFVSPGQSLGNIFATDVVEVALPLKDADLGQLGLPIAFSSS
ADEPGPKVEFSAVVGGKPRTWVGEVVRTGAAINSQTRQINVFAELKDPFGTGADDGAPMAPGLFVTARIEGETLDNVLIA
PRAALRGDDRLFIGDPKEGKLSIRTVDVAYSDRDGAYLRSGVAPGELAITSPIQAAFDGMSITVLERQPDGTVKIHGEKK
TPKDAEAIADAAASEGGEGSAQ
>Mature_421_residues
GRLIAIIAPIAILLVLGVGGVIAVTAMKPEPQKNDEPQAGLNVFAEQVKSGSLTITVEAQGEVSPKREIIVAPQIAGRVS
YVSPDFIDGGFIRRGQVLVRVEAADSELGVVRARSIVATAEQALAREIAEAELAQQDLENLGLTDASPLARREPQLAEAR
AALESAKAQLSEAELSLSRTAIIAPFDGRVRERSADIGQFVSPGQSLGNIFATDVVEVALPLKDADLGQLGLPIAFSSSA
DEPGPKVEFSAVVGGKPRTWVGEVVRTGAAINSQTRQINVFAELKDPFGTGADDGAPMAPGLFVTARIEGETLDNVLIAP
RAALRGDDRLFIGDPKEGKLSIRTVDVAYSDRDGAYLRSGVAPGELAITSPIQAAFDGMSITVLERQPDGTVKIHGEKKT
PKDAEAIADAAASEGGEGSAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=338, Percent_Identity=22.4852071005917, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44093; Mature: 43962

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLIAIIAPIAILLVLGVGGVIAVTAMKPEPQKNDEPQAGLNVFAEQVKSGSLTITVEA
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEE
QGEVSPKREIIVAPQIAGRVSYVSPDFIDGGFIRRGQVLVRVEAADSELGVVRARSIVAT
CCCCCCCCEEEECCHHCCEEEECCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHHHH
AEQALAREIAEAELAQQDLENLGLTDASPLARREPQLAEARAALESAKAQLSEAELSLSR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHEECC
TAIIAPFDGRVRERSADIGQFVSPGQSLGNIFATDVVEVALPLKDADLGQLGLPIAFSSS
EEEEECCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
ADEPGPKVEFSAVVGGKPRTWVGEVVRTGAAINSQTRQINVFAELKDPFGTGADDGAPMA
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
PGLFVTARIEGETLDNVLIAPRAALRGDDRLFIGDPKEGKLSIRTVDVAYSDRDGAYLRS
CCEEEEEEECCCCCCCEEECCHHHHCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHC
GVAPGELAITSPIQAAFDGMSITVLERQPDGTVKIHGEKKTPKDAEAIADAAASEGGEGS
CCCCCCEEECCCHHHHHCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCC
AQ
CC
>Mature Secondary Structure 
GRLIAIIAPIAILLVLGVGGVIAVTAMKPEPQKNDEPQAGLNVFAEQVKSGSLTITVEA
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEE
QGEVSPKREIIVAPQIAGRVSYVSPDFIDGGFIRRGQVLVRVEAADSELGVVRARSIVAT
CCCCCCCCEEEECCHHCCEEEECCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHHHH
AEQALAREIAEAELAQQDLENLGLTDASPLARREPQLAEARAALESAKAQLSEAELSLSR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHEECC
TAIIAPFDGRVRERSADIGQFVSPGQSLGNIFATDVVEVALPLKDADLGQLGLPIAFSSS
EEEEECCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
ADEPGPKVEFSAVVGGKPRTWVGEVVRTGAAINSQTRQINVFAELKDPFGTGADDGAPMA
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
PGLFVTARIEGETLDNVLIAPRAALRGDDRLFIGDPKEGKLSIRTVDVAYSDRDGAYLRS
CCEEEEEEECCCCCCCEEECCHHHHCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHC
GVAPGELAITSPIQAAFDGMSITVLERQPDGTVKIHGEKKTPKDAEAIADAAASEGGEGS
CCCCCCEEECCCHHHHHCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCC
AQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]