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The map label for this gene is etfA [H]

Identifier: 114797076

GI number: 114797076

Start: 3605943

End: 3606872

Strand: Reverse

Name: etfA [H]

Synonym: HNE_3470

Alternate gene names: 114797076

Gene position: 3606872-3605943 (Counterclockwise)

Preceding gene: 114799429

Following gene: 114797883

Centisome position: 97.35

GC content: 60.75

Gene sequence:

>930_bases
ATGGCCGTCCTCGTAATTGCAGAACATCATCACGGCGCCCTGTCGGATGCGACCCACAAGGTCGTCACCGCAGCAATCAA
GTTTGGCGGCGATGTGGACGTGCTGGTCGCCGGTGAGAATGCCGGTACGGTTGCGCCTGAAGCGGCCAAGATCACCGGCG
TTCGTAAAGTGCTGAAAGCCGAAGGCGAGAGCCTGCGCAAGCAGACTGCCGAAGCCATGGAAGCGCTCGTTGTGCCGCTT
ATGTCAGGCTATGACGCGGTGTTCTTTGCCGCCACCACCACGGGCAAGAACGTTGCCCCGCGCATCGCGGCCAAGCTCGA
CGTGATGCAGATCTCTGAAATCATCGGTATTGAAGACGCGTCGACCTTTGTGCGTCCGATCTATGCCGGTAACGCCATCC
AGACCGTCAAATCGTCTGATGCCAAGAAAGTCATCACCGTTCGCGGTACGGCTTTCGGCGCCGCAGAGATGGGTGGCTCG
GCTTCGGTGGAAGACGTGGCGGCGCCTGCCGGTCCGTTCAAATCGGAGTTTGTGTCGGAAGAGATGGTGAAGTCGGATCG
TCCCGAACTCGCCGGCGCCAAGCGCGTCGTCTCGGGTGGCCGCGCGCTCGGCTCGTCTGAGAAGTTCCAGGAAGTCATCT
TCCCGCTCGCCGACAAGCTTGGCGCCGCTGTGGGCGCTTCGCGCGCTGCTGTGGACGCAGGGTATGCTCCGAACGACTAT
CAGGTCGGCCAGACCGGCAAGATCGTTGCGCCGGAACTCTACATCGCCATCGGCATCTCGGGCGCCATCCAGCACCTTGC
CGGCATGAAGGATTCCAAGATCATCGTAGCGATCAACAAGGACGAAGAAGCCCCGATCTTCCAGGTGGCCGATTACGGCC
TGGTCGGCGATCTCTTCAACATCGTTCCGGAACTGACCAAAGCGCTCTGA

Upstream 100 bases:

>100_bases
CGGTTGTGAAGGTCACCGAGCCGCCGACACGCAGCGCCGGTATCAAGGTTGAAGACGTCGCGACGCTGGTTTCGAAACTC
AAGACTGCGGGAGCTGTTTA

Downstream 100 bases:

>100_bases
TCCGGAGCCACGGTAACGAACAAAAAAGCCCGGTGCCCTTGGGGTGCCGGGCTTTTTCTTTGGGGCTGCCCCGCACCTGC
CAGCCGGACTTTGACGCAGT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAVLVIAEHHHGALSDATHKVVTAAIKFGGDVDVLVAGENAGTVAPEAAKITGVRKVLKAEGESLRKQTAEAMEALVVPL
MSGYDAVFFAATTTGKNVAPRIAAKLDVMQISEIIGIEDASTFVRPIYAGNAIQTVKSSDAKKVITVRGTAFGAAEMGGS
ASVEDVAAPAGPFKSEFVSEEMVKSDRPELAGAKRVVSGGRALGSSEKFQEVIFPLADKLGAAVGASRAAVDAGYAPNDY
QVGQTGKIVAPELYIAIGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVGDLFNIVPELTKAL

Sequences:

>Translated_309_residues
MAVLVIAEHHHGALSDATHKVVTAAIKFGGDVDVLVAGENAGTVAPEAAKITGVRKVLKAEGESLRKQTAEAMEALVVPL
MSGYDAVFFAATTTGKNVAPRIAAKLDVMQISEIIGIEDASTFVRPIYAGNAIQTVKSSDAKKVITVRGTAFGAAEMGGS
ASVEDVAAPAGPFKSEFVSEEMVKSDRPELAGAKRVVSGGRALGSSEKFQEVIFPLADKLGAAVGASRAAVDAGYAPNDY
QVGQTGKIVAPELYIAIGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVGDLFNIVPELTKAL
>Mature_308_residues
AVLVIAEHHHGALSDATHKVVTAAIKFGGDVDVLVAGENAGTVAPEAAKITGVRKVLKAEGESLRKQTAEAMEALVVPLM
SGYDAVFFAATTTGKNVAPRIAAKLDVMQISEIIGIEDASTFVRPIYAGNAIQTVKSSDAKKVITVRGTAFGAAEMGGSA
SVEDVAAPAGPFKSEFVSEEMVKSDRPELAGAKRVVSGGRALGSSEKFQEVIFPLADKLGAAVGASRAAVDAGYAPNDYQ
VGQTGKIVAPELYIAIGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVGDLFNIVPELTKAL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=55.9485530546624, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=57.0909090909091, Blast_Score=289, Evalue=2e-78,
Organism=Escherichia coli, GI1786226, Length=235, Percent_Identity=34.8936170212766, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787990, Length=296, Percent_Identity=30.0675675675676, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082157, Length=216, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=55.591054313099, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6325261, Length=313, Percent_Identity=44.7284345047923, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136898, Length=314, Percent_Identity=61.1464968152866, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24652801, Length=314, Percent_Identity=61.1464968152866, Blast_Score=341, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31962; Mature: 31831

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVIAEHHHGALSDATHKVVTAAIKFGGDVDVLVAGENAGTVAPEAAKITGVRKVLKA
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
EGESLRKQTAEAMEALVVPLMSGYDAVFFAATTTGKNVAPRIAAKLDVMQISEIIGIEDA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCH
STFVRPIYAGNAIQTVKSSDAKKVITVRGTAFGAAEMGGSASVEDVAAPAGPFKSEFVSE
HHHHHHHHCCCHHHHHHCCCCCEEEEEECCEECHHHCCCCCCHHHHHCCCCCHHHHHHHH
EMVKSDRPELAGAKRVVSGGRALGSSEKFQEVIFPLADKLGAAVGASRAAVDAGYAPNDY
HHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPELYIAIGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVGDLFN
CCCCCCCEECCEEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
IVPELTKAL
HHHHHHHCC
>Mature Secondary Structure 
AVLVIAEHHHGALSDATHKVVTAAIKFGGDVDVLVAGENAGTVAPEAAKITGVRKVLKA
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
EGESLRKQTAEAMEALVVPLMSGYDAVFFAATTTGKNVAPRIAAKLDVMQISEIIGIEDA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCH
STFVRPIYAGNAIQTVKSSDAKKVITVRGTAFGAAEMGGSASVEDVAAPAGPFKSEFVSE
HHHHHHHHCCCHHHHHHCCCCCEEEEEECCEECHHHCCCCCCHHHHHCCCCCHHHHHHHH
EMVKSDRPELAGAKRVVSGGRALGSSEKFQEVIFPLADKLGAAVGASRAAVDAGYAPNDY
HHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPELYIAIGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVGDLFN
CCCCCCCEECCEEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
IVPELTKAL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]