Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 114797052

GI number: 114797052

Start: 544084

End: 545055

Strand: Reverse

Name: trxB [H]

Synonym: HNE_0548

Alternate gene names: 114797052

Gene position: 545055-544084 (Counterclockwise)

Preceding gene: 114798820

Following gene: 114799066

Centisome position: 14.71

GC content: 63.89

Gene sequence:

>972_bases
ATGGCCGAGACACAACACGCCGAAATCCTGATCATCGGCTCAGGCCCCGCCGGCTGGACCGCCGCCGTCTACGCTGCCCG
CGCCCTGCGCGACACGCTCGTGGTCACCGGCATGCAGCCGGGCGGCCAGCTGACCATCACCACTGAGGTCGAGAACTGGC
CGGGCGAATCCCACATCCAGGGGCCCGAACTGATGGTGAAGATGCAGGAACATGCCGAGAAGATGGGCGCCAAGGTCGCC
AATGATCACATCGCCTCGGTCGATTTCGAAACCCGCCCGTTCAAGGCTGTGGGCGAAAGCGGCACAGTCTACACGGCTGA
TTCTGTCATCATCTCCACCGGCGCGCAGGCCAAATGGCTCGATCTGCCCAGCGAAGAAAAGTTCAAGGGCTTCGGCGTTT
CCGCCTGCGCCACCTGCGATGGCTTCTTCTATCGCGGCAAGGAAGTGCTCGTCATCGGCGGGGGCAACACGGCCGTTGAA
GAGGCGCTGTTCCTGACGAACTTTGCTTCCAAGGTCACCGTCATCCACCGCCGCGACCATTTCCGCGCCGAGAAAATCCT
GCAGGACCGCCTGTTCAAGAACCCCAAGGTCGAAGTGATCTGGAACCATGCGCTGGAAGAAGTCGTCGGCGATGAAAACC
CGCTCGGCGTCACGGCGGCCCGCATCAAGGATGTCACCACCGGCGCCATCCGCGAACTGCCCGTCCACGGCGTCTTTGTC
GCCATTGGCCATGCCCCGTCTACCGAGCTGTTCGTCGGCAAGCTGCCAATGCGCGAAAGCGGCTATCTGATCACCGAGCC
CGGCTCGCCCCGCACCGCCATTCCCGGCGTGTTCGCGGCCGGCGACGTGACAGACGAAACCTACCGTCAGGCCGTCACGG
CCGCCGGCATGGGCTGCATGGCGGCGCTGGACGCCGAACGCTTCCTCTCCGAACAGGAAGCGCATGTAGAAGCGGCTGTT
CCGGCCGAATAG

Upstream 100 bases:

>100_bases
GCAGCAGGCCCGCCGGCGCTTTAACCCTCAGGCCAGACGCCCCATATGGGGCCAGACGACCGGCTGAGACTGCCGGGCCA
GACGCTTCAAGGAGGCCCCG

Downstream 100 bases:

>100_bases
GTCCCTTACAGCATTGCCAAAGCGAGGCGTTCAACGTCTCGCGGCTTGTCCCGCGCCACAACCTCCAGCAGGCGCGCGGC
CCGCGCCTGCATGACCTTAT

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAETQHAEILIIGSGPAGWTAAVYAARALRDTLVVTGMQPGGQLTITTEVENWPGESHIQGPELMVKMQEHAEKMGAKVA
NDHIASVDFETRPFKAVGESGTVYTADSVIISTGAQAKWLDLPSEEKFKGFGVSACATCDGFFYRGKEVLVIGGGNTAVE
EALFLTNFASKVTVIHRRDHFRAEKILQDRLFKNPKVEVIWNHALEEVVGDENPLGVTAARIKDVTTGAIRELPVHGVFV
AIGHAPSTELFVGKLPMRESGYLITEPGSPRTAIPGVFAAGDVTDETYRQAVTAAGMGCMAALDAERFLSEQEAHVEAAV
PAE

Sequences:

>Translated_323_residues
MAETQHAEILIIGSGPAGWTAAVYAARALRDTLVVTGMQPGGQLTITTEVENWPGESHIQGPELMVKMQEHAEKMGAKVA
NDHIASVDFETRPFKAVGESGTVYTADSVIISTGAQAKWLDLPSEEKFKGFGVSACATCDGFFYRGKEVLVIGGGNTAVE
EALFLTNFASKVTVIHRRDHFRAEKILQDRLFKNPKVEVIWNHALEEVVGDENPLGVTAARIKDVTTGAIRELPVHGVFV
AIGHAPSTELFVGKLPMRESGYLITEPGSPRTAIPGVFAAGDVTDETYRQAVTAAGMGCMAALDAERFLSEQEAHVEAAV
PAE
>Mature_322_residues
AETQHAEILIIGSGPAGWTAAVYAARALRDTLVVTGMQPGGQLTITTEVENWPGESHIQGPELMVKMQEHAEKMGAKVAN
DHIASVDFETRPFKAVGESGTVYTADSVIISTGAQAKWLDLPSEEKFKGFGVSACATCDGFFYRGKEVLVIGGGNTAVEE
ALFLTNFASKVTVIHRRDHFRAEKILQDRLFKNPKVEVIWNHALEEVVGDENPLGVTAARIKDVTTGAIRELPVHGVFVA
IGHAPSTELFVGKLPMRESGYLITEPGSPRTAIPGVFAAGDVTDETYRQAVTAAGMGCMAALDAERFLSEQEAHVEAAVP
AE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=57.3667711598746, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI87081763, Length=307, Percent_Identity=34.2019543973941, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=319, Percent_Identity=46.3949843260188, Blast_Score=285, Evalue=8e-78,
Organism=Saccharomyces cerevisiae, GI6320560, Length=319, Percent_Identity=46.3949843260188, Blast_Score=284, Evalue=2e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34631; Mature: 34499

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETQHAEILIIGSGPAGWTAAVYAARALRDTLVVTGMQPGGQLTITTEVENWPGESHIQ
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEEECCCCCEEEEEEECCCCCCCCCCC
GPELMVKMQEHAEKMGAKVANDHIASVDFETRPFKAVGESGTVYTADSVIISTGAQAKWL
CHHHHHHHHHHHHHHCCHHHCCCEEEECCCCCCCHHCCCCCCEEEECEEEEECCCCEEEE
DLPSEEKFKGFGVSACATCDGFFYRGKEVLVIGGGNTAVEEALFLTNFASKVTVIHRRDH
CCCCCCCCCCCCCHHHHHCCCCEECCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCH
FRAEKILQDRLFKNPKVEVIWNHALEEVVGDENPLGVTAARIKDVTTGAIRELPVHGVFV
HHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEHHHHHHCCHHHHHHCCCCEEEE
AIGHAPSTELFVGKLPMRESGYLITEPGSPRTAIPGVFAAGDVTDETYRQAVTAAGMGCM
EECCCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHH
AALDAERFLSEQEAHVEAAVPAE
HHHCHHHHHHHHHHCEEECCCCC
>Mature Secondary Structure 
AETQHAEILIIGSGPAGWTAAVYAARALRDTLVVTGMQPGGQLTITTEVENWPGESHIQ
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEEECCCCCEEEEEEECCCCCCCCCCC
GPELMVKMQEHAEKMGAKVANDHIASVDFETRPFKAVGESGTVYTADSVIISTGAQAKWL
CHHHHHHHHHHHHHHCCHHHCCCEEEECCCCCCCHHCCCCCCEEEECEEEEECCCCEEEE
DLPSEEKFKGFGVSACATCDGFFYRGKEVLVIGGGNTAVEEALFLTNFASKVTVIHRRDH
CCCCCCCCCCCCCHHHHHCCCCEECCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCH
FRAEKILQDRLFKNPKVEVIWNHALEEVVGDENPLGVTAARIKDVTTGAIRELPVHGVFV
HHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEHHHHHHCCHHHHHHCCCCEEEE
AIGHAPSTELFVGKLPMRESGYLITEPGSPRTAIPGVFAAGDVTDETYRQAVTAAGMGCM
EECCCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHH
AALDAERFLSEQEAHVEAAVPAE
HHHCHHHHHHHHHHCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA