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The map label for this gene is kipA [H]

Identifier: 114332426

GI number: 114332426

Start: 2601826

End: 2604159

Strand: Direct

Name: kipA [H]

Synonym: Neut_2475

Alternate gene names: 114332426

Gene position: 2601826-2604159 (Clockwise)

Preceding gene: 114332425

Following gene: 114332427

Centisome position: 97.77

GC content: 49.96

Gene sequence:

>2334_bases
ATGTCCGATAAAACGTTAAGTACGAGTAAAGCCGCCAAACCTGTTATTGAAGTAGTCACACCTGGAATACAAACTACGAT
ACAGGACTACCCTGGAAGACGAGGTTACTGGAATATCGGTGTACCACCTTCCGGGCCGATGGACAGCCTGGCATTCAGGC
TCGCTAATCGCCTGGTGGGAAATGAGGAAGGGCAGGCTGCTATTGAAATCACTTTTTCGGGGCCGACTCTGCGCATTCAT
TACGACAGTGTCATCGCAGTGACGGGCGCTCCCGTCGAAGTAACCTTGAACGGAAAGCCATTAGCGCAATGGAAATCGCA
CAAGGTTAAAGCAGGGACATTACTTGTTTTTGGCGATGTGCTGGATCAGGGCAGCCGGGTTTATCTGGCAATACAGGGCG
GTATTGACGTCCCGGATTATCTCGGCAGCAAATCCACCTTCATGCTGGGCCAGTTCGGCGGGCATGAAGGTCGCATCCTA
CAGGCAGGCGATATGTTGAACATCGCAGCAGACCTCTATGCAGAGTATGTTCCGCATGAACTGCCGCAAGCAGCTGTACC
GCAATATACCCATCACTGGAAAATCGCAGTGCTATATGGCCCGCATGGCGCGCCAGATTTCTTTACAGAAAAAAGCGTCA
CGGGTTTCTTTGCTGCCGAATGGGTCGTGCACCATAACTCTGATCGTACCGGCGTGCGTCTGATCGGCCCGAAACCAGAA
TGGGCAAGGACAGATGGTGGAGAGGCTGGACTGCATCCTTCCAATGTGCACGATGTTCCCTATTCAATTGGCGCGGTGGA
CTTTACTGGAGATCTGCCGGTTATTCTTGGGCCGGATGGTCCCAGCCTGGGTGGGTTCGTCTGTCTGGTAACAGTTGCGT
ATGCTGAGCAGTGGAAAATGGGGCAACTCCAGCCTGGTGATCGCATTACCTTTCAGCGCATCACAGCCGATGATGCAACA
GCACTAGAGGCATCTCAAGATGCATTCGTCCGCAGTTTGCATCTCCCGGAAACAATATCGGCGCCAACTACGATAAAGAC
AGCGACGTCAACATCACCCGATACTCCCATCTTGCATACCATTCCAGAAGCAGGCGAACAGGTGCAGGTTGTGTATCGGC
AGGCGGGAGATAAAAACCTGCTGGTAGAATATGGCTCGATGACGCTTGATTTCAACCTGCGTTTTCGTATCCATGCGCTG
ATGGAATGGTTGCAGCAGGCTGTGGATGGCGGTGATCTGCCGGGAATCGTGGATTTGACGCCCGGCATCCGCTCACTGCA
TATCCGCTTTGATTCCAGAATATTGCCACGCAGCAGATTGCTGGACACGCTGATTTCTGCAGAGCAAAAACTACCTTCCG
TTGAAAATATGGAAGTACCGACACGGATCGTGCATCTGCCGCTTTCCTGGAACGATTCATCCGTTCAGCTGGCTATGAAA
AAATATATGCAATCTGTGCGTAAGGATGCACCATGGAATCCGGACAATATCGAATTTATACGACGAATCAATGGATTGAA
CGGTATTGATGAAGTCAGGAACATTATTTTTGATGCCAGCTATCTAGTGATGGGATTAGGGGATGTCTATCTGGGTGCGC
CACTGGGCACGCCTGTGGATCCAAGACATCGCTTGGTCACGACCAAATACAATCCAGCCCGTACCTGGACACCAGAGAAT
GCGGTAGGGATTGGCGGCGCCTATATGTGTGTGTACGGTATGGAGAGCCCGGGTGGTTATCAGCTGGTGGGACGTACCAT
ACAGATGTGGAACAGCCATATTCAGACAAAAGATTTTAAAGAGGGCAAACCTTGGTTGCTCCGTTTCTTTGATCAGGTGC
GCTTCTACCCTGTGACAGAGGCAGAGCTGGCCAAGATACGCAAAGATTTTCCGAATGGAAGATTTAGTCCGTACATTGAA
GAAGATCGTTTCAATCTCAAACAATACAACAACTTTCTGAAAGAACATGCTGTATCGATTGATGCCTTCAAAACAAAGCA
GAAAGCTGCCTACATAGCTGAGCGTGAACGCTGGAAAGCGGATGGGCAGGAAAATTATACGACCAGTGAACCCCCGGAAA
ACAACTGCGTACCGTACAATATCACCATACCTACAGGAACTTGTGTGGTAAACACACATTTAACCGGTATTGTATGGAAA
TTGCTGGTAAGTGAAGGACAGCATGTGAACACGGGTGATGCTTTAGCGGTATTGGAATCAATGAAGATGGAATTTACGAT
CAAGGCACCTGTCAGCGGCGTAGTACACCAGATATTCAGCCCGGCGGGAAGCAAGGTCTCCGCCAGACAGATATTATTCC
TAATCAGAGAATGA

Upstream 100 bases:

>100_bases
CCTACAACCCCACCCCTATCCGTCTGCTGATCTGGCCAAGAATGTAACAATAGCCGAACCCTGCCCCCTGAGCCAGACAT
TACCGAGCATGGAGAACAGA

Downstream 100 bases:

>100_bases
GCGCAGAATAATGCCTGTTGAGCTATCTGTTTTAATTCTAATGAAACATAATATCGCTAGTTTTGAAAATTAATGATGGT
TATTGGTACGGAGATTCCTT

Product: urea amidolyase related protein

Products: NA

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MSDKTLSTSKAAKPVIEVVTPGIQTTIQDYPGRRGYWNIGVPPSGPMDSLAFRLANRLVGNEEGQAAIEITFSGPTLRIH
YDSVIAVTGAPVEVTLNGKPLAQWKSHKVKAGTLLVFGDVLDQGSRVYLAIQGGIDVPDYLGSKSTFMLGQFGGHEGRIL
QAGDMLNIAADLYAEYVPHELPQAAVPQYTHHWKIAVLYGPHGAPDFFTEKSVTGFFAAEWVVHHNSDRTGVRLIGPKPE
WARTDGGEAGLHPSNVHDVPYSIGAVDFTGDLPVILGPDGPSLGGFVCLVTVAYAEQWKMGQLQPGDRITFQRITADDAT
ALEASQDAFVRSLHLPETISAPTTIKTATSTSPDTPILHTIPEAGEQVQVVYRQAGDKNLLVEYGSMTLDFNLRFRIHAL
MEWLQQAVDGGDLPGIVDLTPGIRSLHIRFDSRILPRSRLLDTLISAEQKLPSVENMEVPTRIVHLPLSWNDSSVQLAMK
KYMQSVRKDAPWNPDNIEFIRRINGLNGIDEVRNIIFDASYLVMGLGDVYLGAPLGTPVDPRHRLVTTKYNPARTWTPEN
AVGIGGAYMCVYGMESPGGYQLVGRTIQMWNSHIQTKDFKEGKPWLLRFFDQVRFYPVTEAELAKIRKDFPNGRFSPYIE
EDRFNLKQYNNFLKEHAVSIDAFKTKQKAAYIAERERWKADGQENYTTSEPPENNCVPYNITIPTGTCVVNTHLTGIVWK
LLVSEGQHVNTGDALAVLESMKMEFTIKAPVSGVVHQIFSPAGSKVSARQILFLIRE

Sequences:

>Translated_777_residues
MSDKTLSTSKAAKPVIEVVTPGIQTTIQDYPGRRGYWNIGVPPSGPMDSLAFRLANRLVGNEEGQAAIEITFSGPTLRIH
YDSVIAVTGAPVEVTLNGKPLAQWKSHKVKAGTLLVFGDVLDQGSRVYLAIQGGIDVPDYLGSKSTFMLGQFGGHEGRIL
QAGDMLNIAADLYAEYVPHELPQAAVPQYTHHWKIAVLYGPHGAPDFFTEKSVTGFFAAEWVVHHNSDRTGVRLIGPKPE
WARTDGGEAGLHPSNVHDVPYSIGAVDFTGDLPVILGPDGPSLGGFVCLVTVAYAEQWKMGQLQPGDRITFQRITADDAT
ALEASQDAFVRSLHLPETISAPTTIKTATSTSPDTPILHTIPEAGEQVQVVYRQAGDKNLLVEYGSMTLDFNLRFRIHAL
MEWLQQAVDGGDLPGIVDLTPGIRSLHIRFDSRILPRSRLLDTLISAEQKLPSVENMEVPTRIVHLPLSWNDSSVQLAMK
KYMQSVRKDAPWNPDNIEFIRRINGLNGIDEVRNIIFDASYLVMGLGDVYLGAPLGTPVDPRHRLVTTKYNPARTWTPEN
AVGIGGAYMCVYGMESPGGYQLVGRTIQMWNSHIQTKDFKEGKPWLLRFFDQVRFYPVTEAELAKIRKDFPNGRFSPYIE
EDRFNLKQYNNFLKEHAVSIDAFKTKQKAAYIAERERWKADGQENYTTSEPPENNCVPYNITIPTGTCVVNTHLTGIVWK
LLVSEGQHVNTGDALAVLESMKMEFTIKAPVSGVVHQIFSPAGSKVSARQILFLIRE
>Mature_776_residues
SDKTLSTSKAAKPVIEVVTPGIQTTIQDYPGRRGYWNIGVPPSGPMDSLAFRLANRLVGNEEGQAAIEITFSGPTLRIHY
DSVIAVTGAPVEVTLNGKPLAQWKSHKVKAGTLLVFGDVLDQGSRVYLAIQGGIDVPDYLGSKSTFMLGQFGGHEGRILQ
AGDMLNIAADLYAEYVPHELPQAAVPQYTHHWKIAVLYGPHGAPDFFTEKSVTGFFAAEWVVHHNSDRTGVRLIGPKPEW
ARTDGGEAGLHPSNVHDVPYSIGAVDFTGDLPVILGPDGPSLGGFVCLVTVAYAEQWKMGQLQPGDRITFQRITADDATA
LEASQDAFVRSLHLPETISAPTTIKTATSTSPDTPILHTIPEAGEQVQVVYRQAGDKNLLVEYGSMTLDFNLRFRIHALM
EWLQQAVDGGDLPGIVDLTPGIRSLHIRFDSRILPRSRLLDTLISAEQKLPSVENMEVPTRIVHLPLSWNDSSVQLAMKK
YMQSVRKDAPWNPDNIEFIRRINGLNGIDEVRNIIFDASYLVMGLGDVYLGAPLGTPVDPRHRLVTTKYNPARTWTPENA
VGIGGAYMCVYGMESPGGYQLVGRTIQMWNSHIQTKDFKEGKPWLLRFFDQVRFYPVTEAELAKIRKDFPNGRFSPYIEE
DRFNLKQYNNFLKEHAVSIDAFKTKQKAAYIAERERWKADGQENYTTSEPPENNCVPYNITIPTGTCVVNTHLTGIVWKL
LVSEGQHVNTGDALAVLESMKMEFTIKAPVSGVVHQIFSPAGSKVSARQILFLIRE

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=318, Percent_Identity=32.0754716981132, Blast_Score=115, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319685, Length=789, Percent_Identity=42.4588086185044, Blast_Score=653, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: NA

Molecular weight: Translated: 85927; Mature: 85796

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKTLSTSKAAKPVIEVVTPGIQTTIQDYPGRRGYWNIGVPPSGPMDSLAFRLANRLVG
CCCCCCCCHHHHCCHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHCC
NEEGQAAIEITFSGPTLRIHYDSVIAVTGAPVEVTLNGKPLAQWKSHKVKAGTLLVFGDV
CCCCCEEEEEEECCCEEEEEECCEEEEECCCEEEEECCCCCHHHHCCCEEEEEEEEEEHH
LDQGSRVYLAIQGGIDVPDYLGSKSTFMLGQFGGHEGRILQAGDMLNIAADLYAEYVPHE
HCCCCEEEEEEECCCCCHHHCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHCCCC
LPQAAVPQYTHHWKIAVLYGPHGAPDFFTEKSVTGFFAAEWVVHHNSDRTGVRLIGPKPE
CCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEECCCCC
WARTDGGEAGLHPSNVHDVPYSIGAVDFTGDLPVILGPDGPSLGGFVCLVTVAYAEQWKM
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCC
GQLQPGDRITFQRITADDATALEASQDAFVRSLHLPETISAPTTIKTATSTSPDTPILHT
CCCCCCCCEEEEEECCCCCHHHHCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEEC
IPEAGEQVQVVYRQAGDKNLLVEYGSMTLDFNLRFRIHALMEWLQQAVDGGDLPGIVDLT
CCCCCCCEEHHHHHCCCCEEEEEECCEEEEEEEEEHHHHHHHHHHHHHCCCCCCCEEECC
PGIRSLHIRFDSRILPRSRLLDTLISAEQKLPSVENMEVPTRIVHLPLSWNDSSVQLAMK
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHH
KYMQSVRKDAPWNPDNIEFIRRINGLNGIDEVRNIIFDASYLVMGLGDVYLGAPLGTPVD
HHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCEECCCCCCCCC
PRHRLVTTKYNPARTWTPENAVGIGGAYMCVYGMESPGGYQLVGRTIQMWNSHIQTKDFK
CCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
EGKPWLLRFFDQVRFYPVTEAELAKIRKDFPNGRFSPYIEEDRFNLKQYNNFLKEHAVSI
CCCHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
DAFKTKQKAAYIAERERWKADGQENYTTSEPPENNCVPYNITIPTGTCVVNTHLTGIVWK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHH
LLVSEGQHVNTGDALAVLESMKMEFTIKAPVSGVVHQIFSPAGSKVSARQILFLIRE
HHHHCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SDKTLSTSKAAKPVIEVVTPGIQTTIQDYPGRRGYWNIGVPPSGPMDSLAFRLANRLVG
CCCCCCCHHHHCCHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHCC
NEEGQAAIEITFSGPTLRIHYDSVIAVTGAPVEVTLNGKPLAQWKSHKVKAGTLLVFGDV
CCCCCEEEEEEECCCEEEEEECCEEEEECCCEEEEECCCCCHHHHCCCEEEEEEEEEEHH
LDQGSRVYLAIQGGIDVPDYLGSKSTFMLGQFGGHEGRILQAGDMLNIAADLYAEYVPHE
HCCCCEEEEEEECCCCCHHHCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHCCCC
LPQAAVPQYTHHWKIAVLYGPHGAPDFFTEKSVTGFFAAEWVVHHNSDRTGVRLIGPKPE
CCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEECCCCC
WARTDGGEAGLHPSNVHDVPYSIGAVDFTGDLPVILGPDGPSLGGFVCLVTVAYAEQWKM
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCC
GQLQPGDRITFQRITADDATALEASQDAFVRSLHLPETISAPTTIKTATSTSPDTPILHT
CCCCCCCCEEEEEECCCCCHHHHCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEEC
IPEAGEQVQVVYRQAGDKNLLVEYGSMTLDFNLRFRIHALMEWLQQAVDGGDLPGIVDLT
CCCCCCCEEHHHHHCCCCEEEEEECCEEEEEEEEEHHHHHHHHHHHHHCCCCCCCEEECC
PGIRSLHIRFDSRILPRSRLLDTLISAEQKLPSVENMEVPTRIVHLPLSWNDSSVQLAMK
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHH
KYMQSVRKDAPWNPDNIEFIRRINGLNGIDEVRNIIFDASYLVMGLGDVYLGAPLGTPVD
HHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCEECCCCCCCCC
PRHRLVTTKYNPARTWTPENAVGIGGAYMCVYGMESPGGYQLVGRTIQMWNSHIQTKDFK
CCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
EGKPWLLRFFDQVRFYPVTEAELAKIRKDFPNGRFSPYIEEDRFNLKQYNNFLKEHAVSI
CCCHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
DAFKTKQKAAYIAERERWKADGQENYTTSEPPENNCVPYNITIPTGTCVVNTHLTGIVWK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHH
LLVSEGQHVNTGDALAVLESMKMEFTIKAPVSGVVHQIFSPAGSKVSARQILFLIRE
HHHHCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]