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The map label for this gene is puuP [H]

Identifier: 114332423

GI number: 114332423

Start: 2598829

End: 2600367

Strand: Direct

Name: puuP [H]

Synonym: Neut_2472

Alternate gene names: 114332423

Gene position: 2598829-2600367 (Clockwise)

Preceding gene: 114332422

Following gene: 114332424

Centisome position: 97.66

GC content: 49.51

Gene sequence:

>1539_bases
ATGACAGCAGTAGAAAAGAAAGACTTATTTTCTGCAGCAGATAGCAGGTCGGCTGACGGAACTGAAACAGAATACGGAAA
CACCCGTGAAACAGGACAGCTTCGTCGCTGTATGAGTGTCTGGAACTGTTGCACCCTGGGATTCTCGGTCGTATCACCGG
TAGTAGGGCTATACGCTATTTTTGGTGTCGAGAATCTGGTAACAGGCGGAGGATGGATTGCCGCACTTATTCTGAGTCTA
TTCATGCAGCTTACGGTAGCAACTGTCTATGCCGAGCTTTCATCACAATTTCCCATTGCCGGTGGCGCCTACAAATGGTC
CATACATTTGATAGGGCCAAAGACAGGCCAGTATGCGGGAATCATTTATGTCAGCTCGGTAATTGCCATGTTGACCACGA
CTGCCTATACAGGAGGGATATGGCTTTCTGCAGTAGTCATGGGTGGAGACACACAAGGTGCCTCAGCAGTTATCTGGGGC
GGTGTGTTCCTATTGATTTGTACACTGGTTAATATCGTTAACCAGCGAATTTACAAAATAATCAACTTACTCGGGGTCAG
TGCTGAAGTATTGGGCTCGATATGTGTCGCACTGATCCTGTTTTTCTTCTTCCGTATCAATCCCGTTTCCGAATTGTTCC
AGCATTTGGGAACGGGGCTGGCGCCTACCAGCATAACTGCTTTCCTGGCGGCATTAGCCATTGCAGGCTGGGCATTTATC
GGATTCGATTCCTGCTCCACTATTGCTGAAGAGGCTCATAACCCCGAGAGAATTATTCCACGTGCAATCTTCCTGTCCCT
GCTGGCGGTAGGCAGCGTGGTGCTTTTCAATTCTTCCGCATTGATGTTGTCGGTTAGTCACGCTATGTTAATCGAGTCCA
GTGCTACTTCTGACCCCATTTCACCGATTATTGCCAGCACCATCGGCGTCTGGGCTGCCAAGCCATTTCTGATAATTGTG
ATGACAGCTTTTCTTTCCTGTGGATCATCGGTAGTTAATTACGCTGCACGCATCGTTTTCTCGATGGCGCGCGAAGGGAA
TCTGCCTACCTTCTTTTCGCATGTCACAAGAAAAACGCAACTGCCGCGCAATGCAATCGCCGGAACCGTGCTTATGGCCA
GTCTCGGACTGCTTTTTGGGCTGAATGATGGCGCAGTTGCAACCATTATTGCTTTCGGAACAGGCGGGTTATATGCCATG
TTTTCCATGACGACAGGCGTTGGTCTGTATGCACGGCTAACTGGCCGGTGGAATCCCACATTGGGCGCGCTTCGACTGGG
GAAATGGGGATTGGCAATCAATATCATAGCTTTTGTCTGGGCACTATTCGAGCTGATCAACATTGGTTGGCCACGCGACT
ATATAGCCGCCCCGGGGGCAAGCTGGTGGCAGCTCTGGGCGGTACCACTTGTGTTGGGCACCCTGTTGATTCTAACAACA
TTGCATGTGCAAACAGGTTACAAGCGCGCGATAAAAAAGGTTTTGGACATTACTGCTCCGGGAGATATCCGGAAGCAGGT
TGATAAAAACACACTGTAA

Upstream 100 bases:

>100_bases
CCCAGGTTGCGGGCTTCCGCAGCTGCAATTAATTTCCCAGCAGTAAATTTTGTTGTTTCCAGCAGCACAAAATGCCCTTA
ACCTTCAAGAGAAGAACTAT

Downstream 100 bases:

>100_bases
CGAGGAGTGAAGGTATGAATCAGATTGTTCAGTATCTTTGGGAAACACATATTCCCGGCGGGTGTCACTGGTCGGGAATT
GTACGTCGAGGAACCACGTT

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MTAVEKKDLFSAADSRSADGTETEYGNTRETGQLRRCMSVWNCCTLGFSVVSPVVGLYAIFGVENLVTGGGWIAALILSL
FMQLTVATVYAELSSQFPIAGGAYKWSIHLIGPKTGQYAGIIYVSSVIAMLTTTAYTGGIWLSAVVMGGDTQGASAVIWG
GVFLLICTLVNIVNQRIYKIINLLGVSAEVLGSICVALILFFFFRINPVSELFQHLGTGLAPTSITAFLAALAIAGWAFI
GFDSCSTIAEEAHNPERIIPRAIFLSLLAVGSVVLFNSSALMLSVSHAMLIESSATSDPISPIIASTIGVWAAKPFLIIV
MTAFLSCGSSVVNYAARIVFSMAREGNLPTFFSHVTRKTQLPRNAIAGTVLMASLGLLFGLNDGAVATIIAFGTGGLYAM
FSMTTGVGLYARLTGRWNPTLGALRLGKWGLAINIIAFVWALFELINIGWPRDYIAAPGASWWQLWAVPLVLGTLLILTT
LHVQTGYKRAIKKVLDITAPGDIRKQVDKNTL

Sequences:

>Translated_512_residues
MTAVEKKDLFSAADSRSADGTETEYGNTRETGQLRRCMSVWNCCTLGFSVVSPVVGLYAIFGVENLVTGGGWIAALILSL
FMQLTVATVYAELSSQFPIAGGAYKWSIHLIGPKTGQYAGIIYVSSVIAMLTTTAYTGGIWLSAVVMGGDTQGASAVIWG
GVFLLICTLVNIVNQRIYKIINLLGVSAEVLGSICVALILFFFFRINPVSELFQHLGTGLAPTSITAFLAALAIAGWAFI
GFDSCSTIAEEAHNPERIIPRAIFLSLLAVGSVVLFNSSALMLSVSHAMLIESSATSDPISPIIASTIGVWAAKPFLIIV
MTAFLSCGSSVVNYAARIVFSMAREGNLPTFFSHVTRKTQLPRNAIAGTVLMASLGLLFGLNDGAVATIIAFGTGGLYAM
FSMTTGVGLYARLTGRWNPTLGALRLGKWGLAINIIAFVWALFELINIGWPRDYIAAPGASWWQLWAVPLVLGTLLILTT
LHVQTGYKRAIKKVLDITAPGDIRKQVDKNTL
>Mature_511_residues
TAVEKKDLFSAADSRSADGTETEYGNTRETGQLRRCMSVWNCCTLGFSVVSPVVGLYAIFGVENLVTGGGWIAALILSLF
MQLTVATVYAELSSQFPIAGGAYKWSIHLIGPKTGQYAGIIYVSSVIAMLTTTAYTGGIWLSAVVMGGDTQGASAVIWGG
VFLLICTLVNIVNQRIYKIINLLGVSAEVLGSICVALILFFFFRINPVSELFQHLGTGLAPTSITAFLAALAIAGWAFIG
FDSCSTIAEEAHNPERIIPRAIFLSLLAVGSVVLFNSSALMLSVSHAMLIESSATSDPISPIIASTIGVWAAKPFLIIVM
TAFLSCGSSVVNYAARIVFSMAREGNLPTFFSHVTRKTQLPRNAIAGTVLMASLGLLFGLNDGAVATIIAFGTGGLYAMF
SMTTGVGLYARLTGRWNPTLGALRLGKWGLAINIIAFVWALFELINIGWPRDYIAAPGASWWQLWAVPLVLGTLLILTTL
HVQTGYKRAIKKVLDITAPGDIRKQVDKNTL

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=372, Percent_Identity=25.2688172043011, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082023, Length=372, Percent_Identity=26.0752688172043, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786302, Length=322, Percent_Identity=24.5341614906832, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=425, Percent_Identity=25.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=415, Percent_Identity=23.1325301204819, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54674; Mature: 54543

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVEKKDLFSAADSRSADGTETEYGNTRETGQLRRCMSVWNCCTLGFSVVSPVVGLYAI
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVENLVTGGGWIAALILSLFMQLTVATVYAELSSQFPIAGGAYKWSIHLIGPKTGQYAG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCHH
IIYVSSVIAMLTTTAYTGGIWLSAVVMGGDTQGASAVIWGGVFLLICTLVNIVNQRIYKI
HHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
INLLGVSAEVLGSICVALILFFFFRINPVSELFQHLGTGLAPTSITAFLAALAIAGWAFI
HHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GFDSCSTIAEEAHNPERIIPRAIFLSLLAVGSVVLFNSSALMLSVSHAMLIESSATSDPI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHEECCCCCCCH
SPIIASTIGVWAAKPFLIIVMTAFLSCGSSVVNYAARIVFSMAREGNLPTFFSHVTRKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
LPRNAIAGTVLMASLGLLFGLNDGAVATIIAFGTGGLYAMFSMTTGVGLYARLTGRWNPT
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCC
LGALRLGKWGLAINIIAFVWALFELINIGWPRDYIAAPGASWWQLWAVPLVLGTLLILTT
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LHVQTGYKRAIKKVLDITAPGDIRKQVDKNTL
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TAVEKKDLFSAADSRSADGTETEYGNTRETGQLRRCMSVWNCCTLGFSVVSPVVGLYAI
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVENLVTGGGWIAALILSLFMQLTVATVYAELSSQFPIAGGAYKWSIHLIGPKTGQYAG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCHH
IIYVSSVIAMLTTTAYTGGIWLSAVVMGGDTQGASAVIWGGVFLLICTLVNIVNQRIYKI
HHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
INLLGVSAEVLGSICVALILFFFFRINPVSELFQHLGTGLAPTSITAFLAALAIAGWAFI
HHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GFDSCSTIAEEAHNPERIIPRAIFLSLLAVGSVVLFNSSALMLSVSHAMLIESSATSDPI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHEECCCCCCCH
SPIIASTIGVWAAKPFLIIVMTAFLSCGSSVVNYAARIVFSMAREGNLPTFFSHVTRKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
LPRNAIAGTVLMASLGLLFGLNDGAVATIIAFGTGGLYAMFSMTTGVGLYARLTGRWNPT
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCC
LGALRLGKWGLAINIIAFVWALFELINIGWPRDYIAAPGASWWQLWAVPLVLGTLLILTT
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LHVQTGYKRAIKKVLDITAPGDIRKQVDKNTL
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]