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The map label for this gene is mnmG

Identifier: 114332389

GI number: 114332389

Start: 2550774

End: 2552699

Strand: Reverse

Name: mnmG

Synonym: Neut_2437

Alternate gene names: 114332389

Gene position: 2552699-2550774 (Counterclockwise)

Preceding gene: 114332390

Following gene: 114332388

Centisome position: 95.93

GC content: 49.43

Gene sequence:

>1926_bases
ATGCATTTTTCAAGAGATTTTGACATTATCGTTGTTGGTGGCGGACATGCCGGAACGGAAGCGGCTCTGGCAGCTGCACG
CATGGGTCAAAAAACATTACTTCTGACGCAAAATCTGGACACATTGGGGCAAATGTCATGCAATCCATCCATTGGAGGAA
TCGGCAAAGGCCACCTGGTTAAGGAAATTGATGCACTGGGTGGGGCTATGGCTGCAGCAATTGATGAAGCAGGCATTCAA
TTTCGCACGCTCAATTCAAGCAAAGGCCCGGCGGTTCGAGCAACACGCGCCCAGGCCGATCGTGTACTGTATCGCCAGGC
CATACGCAAACGGCTGGAAGCACAACCCAATCTGCTGATATTACAATCTACTGTTGATGATCTGCTACTGCTGGACGACA
AGATTACAGGCGTTGCCACGCATCTTGGAATTACCTTCTCGGCGCGCGCCGTGGTGTTGACGGTTGGTACCTTTTTGGGG
GGGCTGGCGCATGTCGGTGACCGGAATTTTCAGGCGGGTAGAGCGGGTGATCCGGCATCAATCAGGCTTGCGCATCGCTT
GCGTGAAATGAATCTATCGGTGGGAAGACTTAAAACCGGCACGCCGCCCCGTATTGATGCACGCACTATTGATTTTCAGT
TTTTGCGCGAGCAGCCAGGAGATGAGCCAATACCAACATTTTCATTCCTGGGAAATACTGCACAACACCCTCGACAGGTG
TCATGCTGGATGACACGCACCAATGAGAAAACGCATGAAATCATTCGCGCCGGGTTGGATCATTCTCCCTTGTATACCGG
GAAAATAGAAGGTATCGGGCCGCGCTACTGTCCATCGATCGAAGACAAGGTGGTGCGTTTTTCTGACAGAGACTCGCATA
CCGTCTTTTTGGAGCCGGAGGGTTTGGAAACCAGCGAAATTTATCCGAATGGAATTTCAACGAGCCTTTCTTTTGAGGTA
CAGGTTGAACTGGTGCGTTCAATCGCCGGCCTGGAAAATGCACACATAACCCGGCCGGGTTATGCAATTGAATATGATTA
TTTCGATCCACGGGCACTCAAAAGATCTTTGGAAACAAAAGCGATCGACGGATTGTTTTTTGCTGGGCAGATCAATGGCA
CTACCGGCTATGAAGAAGCAGCTGCTCAAGGTTTGCTCGCCGGTTTAAACGCCAGTCTCAAGATAAAGGAACAAGAATCC
TGGTGTCCGAGCCGTGATGAGGCTTACCTTGGAGTGCTAGTGGATGATCTGGTTACCCGCGGTGTAACAGAGCCTTACCG
TATGTTTACCAGCCGTGCTGAATTCCGCTTGCAATTAAGGGAAGACAATGCTGACATGCGATTGACGGAAGCCGGGCATC
AATTTGGTCTTGTTGATGAGAAGCGCTGGCAGATTTTTGCTGCCAAGCGGGAAGCAATCGAAACTGAAAAAGCAAGATTA
CGGCGTACCTGGGTGCCCGCTGGTGTCTTGCATAAATTACAAACACTGCAAACATCCGACCAATCTGACGATCGCTCCTA
TTCATTATACGAGCTGTTACGACGCCCCGGAATCAGTTATACAGAGCTGGTGTCATTGTCTGAAGTTGAATCGTCGATGA
TTGACGGCCGGATCGCCCAGCAGTTGGAAATTGATGTCAAATATGAAGGTTACGTAGAACGACAAAGACAGGAAGTTGTT
CGTCATACACAGCATGAAACCATGGTTTTACCAAAAAACCTGGATTACAGTACCGTGCGAGGCCTTTCTAACGAAGTCAC
GCAGAAATTGAATCAGCATCAACCGGAAACAATTGGCCAGGCAGCACGGATTTCTGGTATTACACCGGCAGCCATATCCT
TATTACTGGTACATCTAAAGCGTGGTATGGCACGCCAGGCAGCCAAACAGGAAGAAACGCATGAATCTGGAAAAACAGTT
GCATGA

Upstream 100 bases:

>100_bases
TTGATCAATTTCATATAAAATACCTCCAACTCCTTAAGCAATCTTCATCATATGACTGTCCAAGTCTGTTTAGGCGCACT
GCGAACTGGCATCTGTATTT

Downstream 100 bases:

>100_bases
AGGTCTGGAAGCAATTTCAGGGTTGTCCGCTGATGTGGCACATTTAAGCAGTCGGTTATTACGCTACATTGAACTCATCA
CCAAGTGGAACAGTACTCAT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MHFSRDFDIIVVGGGHAGTEAALAAARMGQKTLLLTQNLDTLGQMSCNPSIGGIGKGHLVKEIDALGGAMAAAIDEAGIQ
FRTLNSSKGPAVRATRAQADRVLYRQAIRKRLEAQPNLLILQSTVDDLLLLDDKITGVATHLGITFSARAVVLTVGTFLG
GLAHVGDRNFQAGRAGDPASIRLAHRLREMNLSVGRLKTGTPPRIDARTIDFQFLREQPGDEPIPTFSFLGNTAQHPRQV
SCWMTRTNEKTHEIIRAGLDHSPLYTGKIEGIGPRYCPSIEDKVVRFSDRDSHTVFLEPEGLETSEIYPNGISTSLSFEV
QVELVRSIAGLENAHITRPGYAIEYDYFDPRALKRSLETKAIDGLFFAGQINGTTGYEEAAAQGLLAGLNASLKIKEQES
WCPSRDEAYLGVLVDDLVTRGVTEPYRMFTSRAEFRLQLREDNADMRLTEAGHQFGLVDEKRWQIFAAKREAIETEKARL
RRTWVPAGVLHKLQTLQTSDQSDDRSYSLYELLRRPGISYTELVSLSEVESSMIDGRIAQQLEIDVKYEGYVERQRQEVV
RHTQHETMVLPKNLDYSTVRGLSNEVTQKLNQHQPETIGQAARISGITPAAISLLLVHLKRGMARQAAKQEETHESGKTV
A

Sequences:

>Translated_641_residues
MHFSRDFDIIVVGGGHAGTEAALAAARMGQKTLLLTQNLDTLGQMSCNPSIGGIGKGHLVKEIDALGGAMAAAIDEAGIQ
FRTLNSSKGPAVRATRAQADRVLYRQAIRKRLEAQPNLLILQSTVDDLLLLDDKITGVATHLGITFSARAVVLTVGTFLG
GLAHVGDRNFQAGRAGDPASIRLAHRLREMNLSVGRLKTGTPPRIDARTIDFQFLREQPGDEPIPTFSFLGNTAQHPRQV
SCWMTRTNEKTHEIIRAGLDHSPLYTGKIEGIGPRYCPSIEDKVVRFSDRDSHTVFLEPEGLETSEIYPNGISTSLSFEV
QVELVRSIAGLENAHITRPGYAIEYDYFDPRALKRSLETKAIDGLFFAGQINGTTGYEEAAAQGLLAGLNASLKIKEQES
WCPSRDEAYLGVLVDDLVTRGVTEPYRMFTSRAEFRLQLREDNADMRLTEAGHQFGLVDEKRWQIFAAKREAIETEKARL
RRTWVPAGVLHKLQTLQTSDQSDDRSYSLYELLRRPGISYTELVSLSEVESSMIDGRIAQQLEIDVKYEGYVERQRQEVV
RHTQHETMVLPKNLDYSTVRGLSNEVTQKLNQHQPETIGQAARISGITPAAISLLLVHLKRGMARQAAKQEETHESGKTV
A
>Mature_641_residues
MHFSRDFDIIVVGGGHAGTEAALAAARMGQKTLLLTQNLDTLGQMSCNPSIGGIGKGHLVKEIDALGGAMAAAIDEAGIQ
FRTLNSSKGPAVRATRAQADRVLYRQAIRKRLEAQPNLLILQSTVDDLLLLDDKITGVATHLGITFSARAVVLTVGTFLG
GLAHVGDRNFQAGRAGDPASIRLAHRLREMNLSVGRLKTGTPPRIDARTIDFQFLREQPGDEPIPTFSFLGNTAQHPRQV
SCWMTRTNEKTHEIIRAGLDHSPLYTGKIEGIGPRYCPSIEDKVVRFSDRDSHTVFLEPEGLETSEIYPNGISTSLSFEV
QVELVRSIAGLENAHITRPGYAIEYDYFDPRALKRSLETKAIDGLFFAGQINGTTGYEEAAAQGLLAGLNASLKIKEQES
WCPSRDEAYLGVLVDDLVTRGVTEPYRMFTSRAEFRLQLREDNADMRLTEAGHQFGLVDEKRWQIFAAKREAIETEKARL
RRTWVPAGVLHKLQTLQTSDQSDDRSYSLYELLRRPGISYTELVSLSEVESSMIDGRIAQQLEIDVKYEGYVERQRQEVV
RHTQHETMVLPKNLDYSTVRGLSNEVTQKLNQHQPETIGQAARISGITPAAISLLLVHLKRGMARQAAKQEETHESGKTV
A

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=642, Percent_Identity=45.0155763239875, Blast_Score=503, Evalue=1e-142,
Organism=Homo sapiens, GI19882217, Length=667, Percent_Identity=43.328335832084, Blast_Score=489, Evalue=1e-138,
Organism=Homo sapiens, GI183227703, Length=682, Percent_Identity=42.375366568915, Blast_Score=484, Evalue=1e-136,
Organism=Escherichia coli, GI2367273, Length=629, Percent_Identity=64.2289348171701, Blast_Score=842, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=625, Percent_Identity=41.92, Blast_Score=482, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6321202, Length=637, Percent_Identity=44.4270015698587, Blast_Score=513, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24658174, Length=631, Percent_Identity=45.8003169572108, Blast_Score=504, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_NITEC (Q0ADD6)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748611.1
- ProteinModelPortal:   Q0ADD6
- SMR:   Q0ADD6
- STRING:   Q0ADD6
- GeneID:   4273516
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2437
- NMPDR:   fig|335283.3.peg.1283
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q0ADD6
- ProtClustDB:   PRK05192
- BioCyc:   NEUT335283:NEUT_2437-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 70976; Mature: 70976

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: BINDING 125-125 BINDING 180-180 BINDING 370-370

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFSRDFDIIVVGGGHAGTEAALAAARMGQKTLLLTQNLDTLGQMSCNPSIGGIGKGHLV
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCCCCCHHH
KEIDALGGAMAAAIDEAGIQFRTLNSSKGPAVRATRAQADRVLYRQAIRKRLEAQPNLLI
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEE
LQSTVDDLLLLDDKITGVATHLGITFSARAVVLTVGTFLGGLAHVGDRNFQAGRAGDPAS
EECCCCHHHEECCCHHHHHHHHCEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCHH
IRLAHRLREMNLSVGRLKTGTPPRIDARTIDFQFLREQPGDEPIPTFSFLGNTAQHPRQV
HHHHHHHHHHCCCCCEECCCCCCCCCCEEEHHHHHHCCCCCCCCCHHHHCCCCCCCCCEE
SCWMTRTNEKTHEIIRAGLDHSPLYTGKIEGIGPRYCPSIEDKVVRFSDRDSHTVFLEPE
EEEEECCCHHHHHHHHHCCCCCCEEECEECCCCCCCCCCCHHHHEEECCCCCCEEEECCC
GLETSEIYPNGISTSLSFEVQVELVRSIAGLENAHITRPGYAIEYDYFDPRALKRSLETK
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEECCCEEEEECCCCHHHHHHHHHHH
AIDGLFFAGQINGTTGYEEAAAQGLLAGLNASLKIKEQESWCPSRDEAYLGVLVDDLVTR
HHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHC
GVTEPYRMFTSRAEFRLQLREDNADMRLTEAGHQFGLVDEKRWQIFAAKREAIETEKARL
CCCHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RRTWVPAGVLHKLQTLQTSDQSDDRSYSLYELLRRPGISYTELVSLSEVESSMIDGRIAQ
HHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHH
QLEIDVKYEGYVERQRQEVVRHTQHETMVLPKNLDYSTVRGLSNEVTQKLNQHQPETIGQ
HEEEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
AARISGITPAAISLLLVHLKRGMARQAAKQEETHESGKTVA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHFSRDFDIIVVGGGHAGTEAALAAARMGQKTLLLTQNLDTLGQMSCNPSIGGIGKGHLV
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCCCCCHHH
KEIDALGGAMAAAIDEAGIQFRTLNSSKGPAVRATRAQADRVLYRQAIRKRLEAQPNLLI
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEE
LQSTVDDLLLLDDKITGVATHLGITFSARAVVLTVGTFLGGLAHVGDRNFQAGRAGDPAS
EECCCCHHHEECCCHHHHHHHHCEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCHH
IRLAHRLREMNLSVGRLKTGTPPRIDARTIDFQFLREQPGDEPIPTFSFLGNTAQHPRQV
HHHHHHHHHHCCCCCEECCCCCCCCCCEEEHHHHHHCCCCCCCCCHHHHCCCCCCCCCEE
SCWMTRTNEKTHEIIRAGLDHSPLYTGKIEGIGPRYCPSIEDKVVRFSDRDSHTVFLEPE
EEEEECCCHHHHHHHHHCCCCCCEEECEECCCCCCCCCCCHHHHEEECCCCCCEEEECCC
GLETSEIYPNGISTSLSFEVQVELVRSIAGLENAHITRPGYAIEYDYFDPRALKRSLETK
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEECCCEEEEECCCCHHHHHHHHHHH
AIDGLFFAGQINGTTGYEEAAAQGLLAGLNASLKIKEQESWCPSRDEAYLGVLVDDLVTR
HHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHC
GVTEPYRMFTSRAEFRLQLREDNADMRLTEAGHQFGLVDEKRWQIFAAKREAIETEKARL
CCCHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RRTWVPAGVLHKLQTLQTSDQSDDRSYSLYELLRRPGISYTELVSLSEVESSMIDGRIAQ
HHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHH
QLEIDVKYEGYVERQRQEVVRHTQHETMVLPKNLDYSTVRGLSNEVTQKLNQHQPETIGQ
HEEEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
AARISGITPAAISLLLVHLKRGMARQAAKQEETHESGKTVA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA