Click here to switch to the map view.

The map label for this gene is proW [C]

Identifier: 114332379

GI number: 114332379

Start: 2539094

End: 2540833

Strand: Reverse

Name: proW [C]

Synonym: Neut_2427

Alternate gene names: 114332379

Gene position: 2540833-2539094 (Counterclockwise)

Preceding gene: 114332380

Following gene: 114332378

Centisome position: 95.48

GC content: 52.07

Gene sequence:

>1740_bases
ATGATGCAACGTTTATCTGTCAGCAAATGGTCACGTCGTTTCTCCGCACTATTCTGGGATGGTGTTGCTGCACTGCTGGT
GCTCGGTCTGGTGGTTTTTCTTGCCCAGGCCAGCCGCGACTTTATGCAGCCTCTGGTGGAATCAGGGCACGATGTCATCA
GTCTTGATCCATCCGCCTTACCGGAGTACGCACTGCGAACATCACTCAGGATGTTGCTGGCAATGGTGCTATCGCTGATT
TTTACCTTTACGTATGCAACCTGGGCGGCCAAGAGTTGGCGCGCTGAACAGATTCTCATCCCGCTGCTCGATATCCTTCA
GTCGGTACCGGTATTGGGTTTTATCTCGATTACGGTGGTGTTCTTCCTGTCCTTTGCACCTGGAAAAATGCTGGGTGCCG
AACTGGCTTCAGTTTTTGCTATCTTTACCAGCCAAGCCTGGAACATGGCGTTCAGTTTTTATCAATCACTGCACACGGTT
CCGAGAGAGCTGGATGAAGTATCGCGCTCGTTTCGGCTCAGTCCTTGGATGCGTTTCTGGAAGCTGGAAGTGCCTTTTGC
AATGCCGGCACTCATCTGGAACATGATGATGTCCATGTCGGGCAGCTGGTTTTTTGTCGTGGCATCCGAAGCAATCAGTG
TGGGTGATACGATCGTCACCCTCCCGGGGATCGGCTCTTATATTGCGTTGGCGATTGATCAGCGCGATCTTGGCGCGATC
GGCTGGGCAATTGCAGTCATGTTGATAGTGATCCTGATTTACGATCAGCTCCTGTTCCGGCCATTGGTGGCCTGGGCAGA
TCGTTTTCGCTTTGAGCAGGAAACCGGAGGAATGCCACCGCCGCACTCCTGGGTGCTGACTGTGCTACATCGTTCACAAT
GGATAACGTTTACCACAGCTTTGTTTGCCAGAATCTGGCGATGGACTTACCGGAAATCGCAACAACCTGCTCGAAAAAAA
GCATTTACCTGGAAAGGAACAGGAACAAACCTGAAGCCGTGGGTAGATTGGCTGTGGTATGGAACAATTACCGTAGTTTG
TGCCATCATTTCATGGAAAATTACGTTCTTTATTTTGCAGGAAGTGGCGCTGGCAGAAGTGGGAACGGCCATGTTCCTGG
GTTTTATAACCATGGTGCGTGTTTTTGTGCTGATCGCGGTTGCCAGTGTTATTTGGGTACCGGTGGGTGTCTGGCTTGGA
CTGAGGCCAGGCGCAGCGCGTATTGCCCAGCCAATTGCCCAATTCATGGCGGCATTCCCAGCTAATCTACTGTTTCCGCC
TGCGGTGTATGGGATCGTAGTACTGCAGCTTGATCCAGATATCTGGCTGAGTCCGTTGATGATCCTGGGAACGCAGTGGT
ATATCCTGTTCAACGTTATTGCAGGCGCATCAACTATTCCAGGCGAGTTGCACGATATCAGCGCTAATCTTGGTGTCCGA
GGATGGTTGTGGTGGCGACGCATTGCGCTGCCAGCAGTGTTTCCTTTTTATGTGACAGGCGCCATTACTGCCTCGGGTGG
ATCATGGAACGCCAGCATTGTTGCCGAAATAGTCAGTTGGGGAAGCACTACATTGCAAGCACATGGCCTGGGCGCCTATA
TTACGGAAGCGACTGTTGCTGGGGATTTTCATCGTGTCGCACTCGGGATCGCAGTCATGAGCGCGTTCGTCGTCGTGATT
AACCGCCTGTTCTGGCGCCCGCTGTATGCATTGGCTGAGCGCAAATTCCGTTTAGGGTGA

Upstream 100 bases:

>100_bases
ACACACCCAAAATACCTCTTCTTTCCTTGCCGCCGTACAAATTAGATGTCCGCCCTCCGGACAGGTATCTTGTGACTATA
CTATCTAGGATCAATCAGAA

Downstream 100 bases:

>100_bases
AAGGAGAATCACATCGATACCGTGTTGCTGGATATTCACGAGATTCACAAATCATTTCGCAAACCGGATGGCAGTGAGTT
GCTCGTGCTTGATGGCATCA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: ABC Transporter Permease; ABC Transporter Membrane Protein; ABC Transporter Nitrate Permease; ABC Transporter; ABC Anion Transporter; ABC-Type Anion Transport System Permease Component; Anion Transporter Permease Protein; Nitrate ABC Transporter Permease; ABC Transporter Inner Membrane Subunit; ABC Transporter Transmembrane Permease Protein; ABC-Type Anion Transport System; ABC-Type Nitrate Transport Permease; ABC Transport System Permease Protein; Transmembrane ABC Transporter Protein; Nitrate Transport System Permease Protein; Nitrate ABC Transporter Permease Protein; Anion ABC Transporter Permease; Taurine ABC Transporter Permease Protein; Sugar ABC Transporter; Sugar ABC Transporter 1 Permease Protein; Sulfonate Transport Permease Protein; Nitrate Transport System Permease

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MMQRLSVSKWSRRFSALFWDGVAALLVLGLVVFLAQASRDFMQPLVESGHDVISLDPSALPEYALRTSLRMLLAMVLSLI
FTFTYATWAAKSWRAEQILIPLLDILQSVPVLGFISITVVFFLSFAPGKMLGAELASVFAIFTSQAWNMAFSFYQSLHTV
PRELDEVSRSFRLSPWMRFWKLEVPFAMPALIWNMMMSMSGSWFFVVASEAISVGDTIVTLPGIGSYIALAIDQRDLGAI
GWAIAVMLIVILIYDQLLFRPLVAWADRFRFEQETGGMPPPHSWVLTVLHRSQWITFTTALFARIWRWTYRKSQQPARKK
AFTWKGTGTNLKPWVDWLWYGTITVVCAIISWKITFFILQEVALAEVGTAMFLGFITMVRVFVLIAVASVIWVPVGVWLG
LRPGAARIAQPIAQFMAAFPANLLFPPAVYGIVVLQLDPDIWLSPLMILGTQWYILFNVIAGASTIPGELHDISANLGVR
GWLWWRRIALPAVFPFYVTGAITASGGSWNASIVAEIVSWGSTTLQAHGLGAYITEATVAGDFHRVALGIAVMSAFVVVI
NRLFWRPLYALAERKFRLG

Sequences:

>Translated_579_residues
MMQRLSVSKWSRRFSALFWDGVAALLVLGLVVFLAQASRDFMQPLVESGHDVISLDPSALPEYALRTSLRMLLAMVLSLI
FTFTYATWAAKSWRAEQILIPLLDILQSVPVLGFISITVVFFLSFAPGKMLGAELASVFAIFTSQAWNMAFSFYQSLHTV
PRELDEVSRSFRLSPWMRFWKLEVPFAMPALIWNMMMSMSGSWFFVVASEAISVGDTIVTLPGIGSYIALAIDQRDLGAI
GWAIAVMLIVILIYDQLLFRPLVAWADRFRFEQETGGMPPPHSWVLTVLHRSQWITFTTALFARIWRWTYRKSQQPARKK
AFTWKGTGTNLKPWVDWLWYGTITVVCAIISWKITFFILQEVALAEVGTAMFLGFITMVRVFVLIAVASVIWVPVGVWLG
LRPGAARIAQPIAQFMAAFPANLLFPPAVYGIVVLQLDPDIWLSPLMILGTQWYILFNVIAGASTIPGELHDISANLGVR
GWLWWRRIALPAVFPFYVTGAITASGGSWNASIVAEIVSWGSTTLQAHGLGAYITEATVAGDFHRVALGIAVMSAFVVVI
NRLFWRPLYALAERKFRLG
>Mature_579_residues
MMQRLSVSKWSRRFSALFWDGVAALLVLGLVVFLAQASRDFMQPLVESGHDVISLDPSALPEYALRTSLRMLLAMVLSLI
FTFTYATWAAKSWRAEQILIPLLDILQSVPVLGFISITVVFFLSFAPGKMLGAELASVFAIFTSQAWNMAFSFYQSLHTV
PRELDEVSRSFRLSPWMRFWKLEVPFAMPALIWNMMMSMSGSWFFVVASEAISVGDTIVTLPGIGSYIALAIDQRDLGAI
GWAIAVMLIVILIYDQLLFRPLVAWADRFRFEQETGGMPPPHSWVLTVLHRSQWITFTTALFARIWRWTYRKSQQPARKK
AFTWKGTGTNLKPWVDWLWYGTITVVCAIISWKITFFILQEVALAEVGTAMFLGFITMVRVFVLIAVASVIWVPVGVWLG
LRPGAARIAQPIAQFMAAFPANLLFPPAVYGIVVLQLDPDIWLSPLMILGTQWYILFNVIAGASTIPGELHDISANLGVR
GWLWWRRIALPAVFPFYVTGAITASGGSWNASIVAEIVSWGSTTLQAHGLGAYITEATVAGDFHRVALGIAVMSAFVVVI
NRLFWRPLYALAERKFRLG

Specific function: Involved In A Multicomponent Binding-Protein-Dependent Transport System For Glycine Betaine/L-Proline. [C]

COG id: COG4986

COG function: function code P; ABC-type anion transport system, duplicated permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789033, Length=180, Percent_Identity=26.1111111111111, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64823; Mature: 64823

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQRLSVSKWSRRFSALFWDGVAALLVLGLVVFLAQASRDFMQPLVESGHDVISLDPSAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
PEYALRTSLRMLLAMVLSLIFTFTYATWAAKSWRAEQILIPLLDILQSVPVLGFISITVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
FFLSFAPGKMLGAELASVFAIFTSQAWNMAFSFYQSLHTVPRELDEVSRSFRLSPWMRFW
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KLEVPFAMPALIWNMMMSMSGSWFFVVASEAISVGDTIVTLPGIGSYIALAIDQRDLGAI
EEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCEEEECCCCCCEEEEEECCCCHHHH
GWAIAVMLIVILIYDQLLFRPLVAWADRFRFEQETGGMPPPHSWVLTVLHRSQWITFTTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHCCHHHHHHH
LFARIWRWTYRKSQQPARKKAFTWKGTGTNLKPWVDWLWYGTITVVCAIISWKITFFILQ
HHHHHHHHHHHCCCCCHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVALAEVGTAMFLGFITMVRVFVLIAVASVIWVPVGVWLGLRPGAARIAQPIAQFMAAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
ANLLFPPAVYGIVVLQLDPDIWLSPLMILGTQWYILFNVIAGASTIPGELHDISANLGVR
CCCCCCCHHHEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCH
GWLWWRRIALPAVFPFYVTGAITASGGSWNASIVAEIVSWGSTTLQAHGLGAYITEATVA
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHC
GDFHRVALGIAVMSAFVVVINRLFWRPLYALAERKFRLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMQRLSVSKWSRRFSALFWDGVAALLVLGLVVFLAQASRDFMQPLVESGHDVISLDPSAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
PEYALRTSLRMLLAMVLSLIFTFTYATWAAKSWRAEQILIPLLDILQSVPVLGFISITVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
FFLSFAPGKMLGAELASVFAIFTSQAWNMAFSFYQSLHTVPRELDEVSRSFRLSPWMRFW
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KLEVPFAMPALIWNMMMSMSGSWFFVVASEAISVGDTIVTLPGIGSYIALAIDQRDLGAI
EEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCEEEECCCCCCEEEEEECCCCHHHH
GWAIAVMLIVILIYDQLLFRPLVAWADRFRFEQETGGMPPPHSWVLTVLHRSQWITFTTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHCCHHHHHHH
LFARIWRWTYRKSQQPARKKAFTWKGTGTNLKPWVDWLWYGTITVVCAIISWKITFFILQ
HHHHHHHHHHHCCCCCHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVALAEVGTAMFLGFITMVRVFVLIAVASVIWVPVGVWLGLRPGAARIAQPIAQFMAAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
ANLLFPPAVYGIVVLQLDPDIWLSPLMILGTQWYILFNVIAGASTIPGELHDISANLGVR
CCCCCCCHHHEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCH
GWLWWRRIALPAVFPFYVTGAITASGGSWNASIVAEIVSWGSTTLQAHGLGAYITEATVA
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHC
GDFHRVALGIAVMSAFVVVINRLFWRPLYALAERKFRLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA