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The map label for this gene is argB

Identifier: 114332341

GI number: 114332341

Start: 2499222

End: 2500109

Strand: Reverse

Name: argB

Synonym: Neut_2384

Alternate gene names: 114332341

Gene position: 2500109-2499222 (Counterclockwise)

Preceding gene: 114332342

Following gene: 114332340

Centisome position: 93.95

GC content: 47.41

Gene sequence:

>888_bases
ATGCAATCTTCCCTTGCGGTTAACGAAAAAGTCGAAATCCTCGCTGAGGCATTGCCATACATACGACGCTTCCATAATAA
AACCATCGTAATCAAATACGGCGGCAATGCTATGACCGAGGAAATACTCAAACAAAGTTTTGCTAAAGATGTGGTATTGC
TGAAATTGGTCGGCATGAACCCGGTCATCGTCCATGGCGGCGGCCCGCAAATAGACAGCATGCTGAAGCGCGTCGGTAAG
GAAGGCGTCTTCATACAAGGGATGCGAGTTACAGATGCCGAAACTATGGATATCGTCGAGATGATACTTGGCGGGCTTAT
CAACAAAGAAATTGTCAATCTTATCAACCGTCATGGTGGGCAAGCAGTAGGGCTCACCGGCAAAGACGGAATGTTTATTC
GCGCGAAAAGAATGCTGATCAAAGACAAAGAAGATGCCGAGAAGTGGATCAATATTGGCCAGGTTGGCGAAATAGAGTAT
ATCGATCCCTCGCTGATCAAGCTACTGGACGCTCGCGACTTCATTCCTGTAATAGCCCCTATCGGTGTCGGTGAAGAGGG
TGAATCCTACAATATCAATGCTGATCTTGTTGCAGGTCGCCTAGCGGAGACACTCAAAGCTGAAAAGCTGATATTAATGA
CCAATACACCTGGTGTACTGGATAAAAATGGCAATCTGCTCACAGGCCTGACTGCCAGCCGAGTAGATGAACTATTTGCC
GATGGCACCATCTCCGGCGGAATGTTGCCCAAAATCAAATCAGCGCTGGATGCCGTAAAGAATGGTGTCAAATCCTGCCA
TATCATCGACGGACGTGTACAACATGCCCTTTTGCTTGAAATACTGACTGATGAAGGAGTGGGGACCTTGATCAAAAGCG
AGGGGTAA

Upstream 100 bases:

>100_bases
TGGTACGGCTCAAATCCTTCCTTCAAGCAAGCAGTTAAATTGTCCGGGGCACTCCACACACACCGATTTCACCATAAACA
ATATACAATCCCTCTTCACC

Downstream 100 bases:

>100_bases
AGAACAAACTGGAGCAGAGGTAATCTGCTCTGCCTTGATTCACTGAAGGGAGAGGTTGCTTGTCTTGGAAGACTTCTTTG
AACAGGCTCTAAAAACATCT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQSSLAVNEKVEILAEALPYIRRFHNKTIVIKYGGNAMTEEILKQSFAKDVVLLKLVGMNPVIVHGGGPQIDSMLKRVGK
EGVFIQGMRVTDAETMDIVEMILGGLINKEIVNLINRHGGQAVGLTGKDGMFIRAKRMLIKDKEDAEKWINIGQVGEIEY
IDPSLIKLLDARDFIPVIAPIGVGEEGESYNINADLVAGRLAETLKAEKLILMTNTPGVLDKNGNLLTGLTASRVDELFA
DGTISGGMLPKIKSALDAVKNGVKSCHIIDGRVQHALLLEILTDEGVGTLIKSEG

Sequences:

>Translated_295_residues
MQSSLAVNEKVEILAEALPYIRRFHNKTIVIKYGGNAMTEEILKQSFAKDVVLLKLVGMNPVIVHGGGPQIDSMLKRVGK
EGVFIQGMRVTDAETMDIVEMILGGLINKEIVNLINRHGGQAVGLTGKDGMFIRAKRMLIKDKEDAEKWINIGQVGEIEY
IDPSLIKLLDARDFIPVIAPIGVGEEGESYNINADLVAGRLAETLKAEKLILMTNTPGVLDKNGNLLTGLTASRVDELFA
DGTISGGMLPKIKSALDAVKNGVKSCHIIDGRVQHALLLEILTDEGVGTLIKSEG
>Mature_295_residues
MQSSLAVNEKVEILAEALPYIRRFHNKTIVIKYGGNAMTEEILKQSFAKDVVLLKLVGMNPVIVHGGGPQIDSMLKRVGK
EGVFIQGMRVTDAETMDIVEMILGGLINKEIVNLINRHGGQAVGLTGKDGMFIRAKRMLIKDKEDAEKWINIGQVGEIEY
IDPSLIKLLDARDFIPVIAPIGVGEEGESYNINADLVAGRLAETLKAEKLILMTNTPGVLDKNGNLLTGLTASRVDELFA
DGTISGGMLPKIKSALDAVKNGVKSCHIIDGRVQHALLLEILTDEGVGTLIKSEG

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=291, Percent_Identity=30.5841924398625, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI145693208, Length=245, Percent_Identity=33.8775510204082, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320913, Length=281, Percent_Identity=25.9786476868327, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_NITEC (Q0ADI4)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748563.1
- ProteinModelPortal:   Q0ADI4
- SMR:   Q0ADI4
- STRING:   Q0ADI4
- GeneID:   4272516
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2384
- NMPDR:   fig|335283.3.peg.675
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q0ADI4
- ProtClustDB:   PRK00942
- BioCyc:   NEUT335283:NEUT_2384-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31905; Mature: 31905

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSLAVNEKVEILAEALPYIRRFHNKTIVIKYGGNAMTEEILKQSFAKDVVLLKLVGMN
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCC
PVIVHGGGPQIDSMLKRVGKEGVFIQGMRVTDAETMDIVEMILGGLINKEIVNLINRHGG
EEEEECCCCCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAVGLTGKDGMFIRAKRMLIKDKEDAEKWINIGQVGEIEYIDPSLIKLLDARDFIPVIAP
CEEEECCCCCEEEEEHHHHHCCHHHHHHHHCCCCCCCEEECCHHHHHHHHCCCCHHHEEE
IGVGEEGESYNINADLVAGRLAETLKAEKLILMTNTPGVLDKNGNLLTGLTASRVDELFA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCEECCCCEEECCHHHHHHHHHH
DGTISGGMLPKIKSALDAVKNGVKSCHIIDGRVQHALLLEILTDEGVGTLIKSEG
CCCCCCCCHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure
MQSSLAVNEKVEILAEALPYIRRFHNKTIVIKYGGNAMTEEILKQSFAKDVVLLKLVGMN
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCC
PVIVHGGGPQIDSMLKRVGKEGVFIQGMRVTDAETMDIVEMILGGLINKEIVNLINRHGG
EEEEECCCCCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAVGLTGKDGMFIRAKRMLIKDKEDAEKWINIGQVGEIEYIDPSLIKLLDARDFIPVIAP
CEEEECCCCCEEEEEHHHHHCCHHHHHHHHCCCCCCCEEECCHHHHHHHHCCCCHHHEEE
IGVGEEGESYNINADLVAGRLAETLKAEKLILMTNTPGVLDKNGNLLTGLTASRVDELFA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCEECCCCEEECCHHHHHHHHHH
DGTISGGMLPKIKSALDAVKNGVKSCHIIDGRVQHALLLEILTDEGVGTLIKSEG
CCCCCCCCHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA