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The map label for this gene is coaD

Identifier: 114332301

GI number: 114332301

Start: 2467240

End: 2467734

Strand: Reverse

Name: coaD

Synonym: Neut_2341

Alternate gene names: 114332301

Gene position: 2467734-2467240 (Counterclockwise)

Preceding gene: 114332302

Following gene: 114332300

Centisome position: 92.74

GC content: 46.06

Gene sequence:

>495_bases
ATGGATAAAGTTATTTACCCAGGTACGTTTGATCCGATTACCCATGGGCATGAGGATCTGGTATATCGTGCGTCGAGATT
ATTTGGCAAGGTGATTGTGGCGGTTGCTGTCAGTAGTGGAAAAGCACCTTTTTTCTCGCTGGAAGAACGGGTGAAAATGG
CCAGAAACGTGCTGACCGGATATTCCAATGTTGAAGTAACGGGATTTTCCGGCCTGCTGATGGAATTCGCGCGGCAACAG
GATGCTCATATCATCATTCGCGGTCTGCGTGCCGTATCTGATTTTGAGTATGAATTTCAACTGGCGGGCATGAATCGCGG
CTTGTATCCGGACGTGGAGACCATTTTTCTGACGCCATCTGAACAATATATGTTTATCTCCGCCACGATTGTGCGTGAAA
TTGCCCGTTTGGGAGGAGATGTAAGCAAATTTGTACATCCTCTTGTGATCGAGCGGTTACGTCAGAAAAAGATAGAAATG
AATAATGGAGAGTAA

Upstream 100 bases:

>100_bases
GCTGAAAGCAGTGACAAGTTATTGCCCGATAATACCTGGTTGATCTGCAAGCAAGGGCGAGCAAGCCATGTTTATTATTG
CCTCTTGACTCTGAATCTTG

Downstream 100 bases:

>100_bases
TAAAAATGGCACTGATCATTACTGATGAATGCATCAATTGCGATGTGTGTGAACCTGAATGTCCTAACCAGGCAATTTCA
CAGGGGGAGGAAATTTACGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MDKVIYPGTFDPITHGHEDLVYRASRLFGKVIVAVAVSSGKAPFFSLEERVKMARNVLTGYSNVEVTGFSGLLMEFARQQ
DAHIIIRGLRAVSDFEYEFQLAGMNRGLYPDVETIFLTPSEQYMFISATIVREIARLGGDVSKFVHPLVIERLRQKKIEM
NNGE

Sequences:

>Translated_164_residues
MDKVIYPGTFDPITHGHEDLVYRASRLFGKVIVAVAVSSGKAPFFSLEERVKMARNVLTGYSNVEVTGFSGLLMEFARQQ
DAHIIIRGLRAVSDFEYEFQLAGMNRGLYPDVETIFLTPSEQYMFISATIVREIARLGGDVSKFVHPLVIERLRQKKIEM
NNGE
>Mature_164_residues
MDKVIYPGTFDPITHGHEDLVYRASRLFGKVIVAVAVSSGKAPFFSLEERVKMARNVLTGYSNVEVTGFSGLLMEFARQQ
DAHIIIRGLRAVSDFEYEFQLAGMNRGLYPDVETIFLTPSEQYMFISATIVREIARLGGDVSKFVHPLVIERLRQKKIEM
NNGE

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=143, Percent_Identity=55.9440559440559, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_NITEC (Q0ADM4)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748523.1
- ProteinModelPortal:   Q0ADM4
- SMR:   Q0ADM4
- STRING:   Q0ADM4
- GeneID:   4272765
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2341
- NMPDR:   fig|335283.3.peg.329
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q0ADM4
- ProtClustDB:   PRK00168
- BioCyc:   NEUT335283:NEUT_2341-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18519; Mature: 18519

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVIYPGTFDPITHGHEDLVYRASRLFGKVIVAVAVSSGKAPFFSLEERVKMARNVLTG
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
YSNVEVTGFSGLLMEFARQQDAHIIIRGLRAVSDFEYEFQLAGMNRGLYPDVETIFLTPS
CCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCC
EQYMFISATIVREIARLGGDVSKFVHPLVIERLRQKKIEMNNGE
CCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDKVIYPGTFDPITHGHEDLVYRASRLFGKVIVAVAVSSGKAPFFSLEERVKMARNVLTG
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
YSNVEVTGFSGLLMEFARQQDAHIIIRGLRAVSDFEYEFQLAGMNRGLYPDVETIFLTPS
CCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCC
EQYMFISATIVREIARLGGDVSKFVHPLVIERLRQKKIEMNNGE
CCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA