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The map label for this gene is insF1 [C]

Identifier: 114332157

GI number: 114332157

Start: 2324032

End: 2324853

Strand: Reverse

Name: insF1 [C]

Synonym: Neut_2192

Alternate gene names: 114332157

Gene position: 2324853-2324032 (Counterclockwise)

Preceding gene: 114332158

Following gene: 114332156

Centisome position: 87.37

GC content: 45.38

Gene sequence:

>822_bases
GTGTTATCGATGTGCCGATTTTTACAGGTCTCACAGAGTGCTTACTATGATTGGCTGCATCGAATTCCTTCATTCAGGGA
ACGAGAAGACGAGCAACTCAGCAGTATTGTAAAAAAATTATTTAAAAAAAGCCGGAATACATACGGCACCCGCCGTCTCA
AAATAGCTATGTCTCACCAAGGCCGATCCGTGGGTCGGCGGCGAATAAGCCGGCTAATGAAGGAAGCCGGACTGGCCTGT
AAAACCAAACGTCGATTTAAAGCTACCACTCATTCAAAGCATGAATTGCCTATTGCGCCTAATTATTTGGATCGTCAGTT
TTCCATAGATCAGATAAATCAGGTATATGTGGGCGATCTCACTTATATTCATACCCTGGAAGGCTGGTTGTATCTGGCGG
TCGTGATCGACTTGTTTTCCCGGCAGGTCGTAGGCTGGTCAATGGCCGCACATATGAAAACACAGTTAGTCAACGATGCG
CTCCAGATGGCTATTTGGAAACGTAAACCCGACAAAGGCCTGTTATGGCATACCGATCGGGGTAGCCAATACGCCTCAGA
AAGTCACCGGCAATTACTAAAGCAGCATGGCATCCAACAAAGCATGAGCCGGAAGGGAAATTGCTGGGACAACGCCGTGT
CGGAAAGCTTCTTCCATACCTTAAAAATAGAATTGATCCATCATCAAACGTTTCATTCTCGGGAAGAAGCTAAACAGGCT
GTGTTTGAATATATCGAAGTGTTTTACAACCGAGAGCGATTGCATTCAGCTAATGGATATATATCGCCCGTTGATTTCGA
GTTGCAGCAAAATGCTGCTTAA

Upstream 100 bases:

>100_bases
TGACCGAGGAGCGCGACCTATTAAAAAAGGCTGCCGCGTACTTTGCCAAGGAGCAACGGTGAAGTACGCCTGGATCAAAC
AGCATCAAGGTGAATTCACC

Downstream 100 bases:

>100_bases
CTTTGTGTCCAGAAAAGTGTTGACACATCATTATGTTATCAACCGGTCGACTGTATTTACTGATCCAGGTATGTAAGGTG
TTTTCATTCACGCCAATTTC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLSMCRFLQVSQSAYYDWLHRIPSFREREDEQLSSIVKKLFKKSRNTYGTRRLKIAMSHQGRSVGRRRISRLMKEAGLAC
KTKRRFKATTHSKHELPIAPNYLDRQFSIDQINQVYVGDLTYIHTLEGWLYLAVVIDLFSRQVVGWSMAAHMKTQLVNDA
LQMAIWKRKPDKGLLWHTDRGSQYASESHRQLLKQHGIQQSMSRKGNCWDNAVSESFFHTLKIELIHHQTFHSREEAKQA
VFEYIEVFYNRERLHSANGYISPVDFELQQNAA

Sequences:

>Translated_273_residues
MLSMCRFLQVSQSAYYDWLHRIPSFREREDEQLSSIVKKLFKKSRNTYGTRRLKIAMSHQGRSVGRRRISRLMKEAGLAC
KTKRRFKATTHSKHELPIAPNYLDRQFSIDQINQVYVGDLTYIHTLEGWLYLAVVIDLFSRQVVGWSMAAHMKTQLVNDA
LQMAIWKRKPDKGLLWHTDRGSQYASESHRQLLKQHGIQQSMSRKGNCWDNAVSESFFHTLKIELIHHQTFHSREEAKQA
VFEYIEVFYNRERLHSANGYISPVDFELQQNAA
>Mature_273_residues
MLSMCRFLQVSQSAYYDWLHRIPSFREREDEQLSSIVKKLFKKSRNTYGTRRLKIAMSHQGRSVGRRRISRLMKEAGLAC
KTKRRFKATTHSKHELPIAPNYLDRQFSIDQINQVYVGDLTYIHTLEGWLYLAVVIDLFSRQVVGWSMAAHMKTQLVNDA
LQMAIWKRKPDKGLLWHTDRGSQYASESHRQLLKQHGIQQSMSRKGNCWDNAVSESFFHTLKIELIHHQTFHSREEAKQA
VFEYIEVFYNRERLHSANGYISPVDFELQQNAA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=233, Percent_Identity=33.9055793991416, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1788405, Length=267, Percent_Identity=44.9438202247191, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1787263, Length=267, Percent_Identity=44.9438202247191, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1786753, Length=267, Percent_Identity=44.9438202247191, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1786570, Length=267, Percent_Identity=44.9438202247191, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1786490, Length=267, Percent_Identity=44.9438202247191, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1789981, Length=234, Percent_Identity=34.6153846153846, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32105; Mature: 32105

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSMCRFLQVSQSAYYDWLHRIPSFREREDEQLSSIVKKLFKKSRNTYGTRRLKIAMSHQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GRSVGRRRISRLMKEAGLACKTKRRFKATTHSKHELPIAPNYLDRQFSIDQINQVYVGDL
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHCHHHCCCH
TYIHTLEGWLYLAVVIDLFSRQVVGWSMAAHMKTQLVNDALQMAIWKRKPDKGLLWHTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
GSQYASESHRQLLKQHGIQQSMSRKGNCWDNAVSESFFHTLKIELIHHQTFHSREEAKQA
CCHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VFEYIEVFYNRERLHSANGYISPVDFELQQNAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSMCRFLQVSQSAYYDWLHRIPSFREREDEQLSSIVKKLFKKSRNTYGTRRLKIAMSHQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GRSVGRRRISRLMKEAGLACKTKRRFKATTHSKHELPIAPNYLDRQFSIDQINQVYVGDL
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHCHHHCCCH
TYIHTLEGWLYLAVVIDLFSRQVVGWSMAAHMKTQLVNDALQMAIWKRKPDKGLLWHTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
GSQYASESHRQLLKQHGIQQSMSRKGNCWDNAVSESFFHTLKIELIHHQTFHSREEAKQA
CCHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VFEYIEVFYNRERLHSANGYISPVDFELQQNAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]