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The map label for this gene is speA [H]

Identifier: 114332153

GI number: 114332153

Start: 2320426

End: 2322384

Strand: Direct

Name: speA [H]

Synonym: Neut_2188

Alternate gene names: 114332153

Gene position: 2320426-2322384 (Clockwise)

Preceding gene: 114332152

Following gene: 114332159

Centisome position: 87.2

GC content: 47.93

Gene sequence:

>1959_bases
ATGACCAATGAAGCAGTAGCAAAACACGATTGGTCCTGTGAGGATTCGCAGGCACTTTATGCCATGAGTAAATGGGGAGA
TGGCTTTTATTCGGTGAACAAGATGGGGCATGTTTCTGTTCGTCCTATAGAAGGTCAGGATCTGCACATAGATATCATAG
ATGTAATTCAATCAGCTCGCTCCGAAGGTGCTTCTCTACCAATGCTGATTCGTTTTCAGGATGTGATAAGTTCGCGCGTG
CGACGCCTGAATCAAACGTTTCGGAAGGCGATTCATGAAAGTGGTTACGAAGGGACATATCGCAGTATTTATCCTATTAA
AGTGAATCAGCTGCAAGAAGTGGTGGCAGAGGTACTGGAAGCTGGTCAAGAATTTAACATTGGACTGGAATGTGGCTCCA
AAGCCGAGTTATTAGCCATGCTGCCGCTGGTTGCCGATGAAACACTGCTGCTTTGCAATGGCGTAAAAGACCGCACGATG
TTGACCCTGATGCTGAATGCGCAGCAAATCGGACAGCAAGTGATGCCCATCATTGAAAAATACTCGGAGTTTGAGCAGTT
GATGAATTTGGCAGAAGCACGCCAGATGAAACCGCGGCTGGGTGTGCGATTAAAGCTGAACACCAAAGGATCGGGACGTT
GGTTTGAGTCCGGCGGTGCAAATTCCAAGTTTGGACTGACTATTTCAGAGCTGGTACAACTGATACGGACATTGGAAAAT
CGGGAGATGGCCGGGCAACTGGAACTGCTGCATTTTCATCTGGGAAGTCAAATTGCTGATATTCAGGTACTACGAAGTGC
CATCAGAGAAATCATGCAGGTTTACGCTGATTTGATGTTGCGGGGGATGCAGATCAAGTATCTGGATGTCGGTGGCGGAC
TCGGAGTGAATTACGGTGGTGATTACGACAACCCGGAATCATCCATTAATTACGGACTGCGCGAGTATGCCAATGTAGTA
GTTTATACGGTTAAGGAAATTTGTGATCAGCGGCAAGTACCCATGCCGCAACTTTTGTCAGAAAGTGGTCGCGCACTCAC
TGCGCATCACTCCGTGCTGGTGGTTCCTGTTTTGGGTGTACACAAGCCGGACAGTCCGTACATGGCCGAATCTCCGGCTG
AACTACCTGCCGTGGTGTTACGAATGACGTCGGTATATAGCGATGCGCAATCTGCGGAGAAAATGAGTACGCTGCTGGAA
TGCTATCACGATGCACAAGAAATCCGTCAGGAGACCGAACAGATGGCGCGGTTGGGTTATCTGTCTGTTGAACACATGGC
GCAATCGGATAGTTTGTACTGGAGTATTTGCCGCGAGGTGCTGCGCAAGCTAACGGCGATTGGGTCGATTCCGGTCACAG
CTGAGCAGATTGAGTTGGAGAAGCAGCTTACGGACATGTATCTGGGAGATTTTTCCGTATTTCATTCGATTATCGACCAC
TGGGCCATCGGACAGGTATTCCCCGTGATGCCTCTCCATCGGTTGTGGAATAAACCTGAACGACGCGGTCAACTGGTTGA
TTTAACCTGCGACTCGGATGGCAAGGTAAGTCAGTATGTAACATCGTCCGGCACCAGTGATTGGTTGCCTTTGCATAATT
TTCGTCAAGATGAATCCTATTATCTGGGTATTTTTCTCGTCGGGGCTTATCAAGAGATACTGGGAGACGCTCACAATCTT
TTCGGACGTGTAGGCGAAGTTCACGTTTATGCAAAAGCAGAAGAAGCAAACGGTTTTTGGATCGAGGCACTGCTGAAGGG
AATTAGTGTGAAGGAAATGCTGAGCCAGGTTCAGTATTTTCCCAATGACCTGGATCGCCGTATGTCGGAGTTTATCCGCA
GACAGATAAATGCTGGACGTATCAAGCCTGCAGAAGGAACACGAATTCTTAATAATTATACTCAGCGCTTGGGAGATACC
ACTTACTGTGATGTTTCTTCCAATGAACCGTTATCGTAG

Upstream 100 bases:

>100_bases
ATCATGCTGAAATTACTGCGCTAGCGGCTGCACAGATTGCAGTTGAATTGTTATGTCTTTACGCTGAAAGTCACAGACAA
AGAAATTGAAAGAGTAATCG

Downstream 100 bases:

>100_bases
CGCAGCGACGACGAGCTCGGCAGGCATAGTGGGCGCCATGATGGCCCAACCGATGATTTTGCGTGAGTACAGGTCCATGA
CGGCGGCCAGGTAAAGCCAG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MTNEAVAKHDWSCEDSQALYAMSKWGDGFYSVNKMGHVSVRPIEGQDLHIDIIDVIQSARSEGASLPMLIRFQDVISSRV
RRLNQTFRKAIHESGYEGTYRSIYPIKVNQLQEVVAEVLEAGQEFNIGLECGSKAELLAMLPLVADETLLLCNGVKDRTM
LTLMLNAQQIGQQVMPIIEKYSEFEQLMNLAEARQMKPRLGVRLKLNTKGSGRWFESGGANSKFGLTISELVQLIRTLEN
REMAGQLELLHFHLGSQIADIQVLRSAIREIMQVYADLMLRGMQIKYLDVGGGLGVNYGGDYDNPESSINYGLREYANVV
VYTVKEICDQRQVPMPQLLSESGRALTAHHSVLVVPVLGVHKPDSPYMAESPAELPAVVLRMTSVYSDAQSAEKMSTLLE
CYHDAQEIRQETEQMARLGYLSVEHMAQSDSLYWSICREVLRKLTAIGSIPVTAEQIELEKQLTDMYLGDFSVFHSIIDH
WAIGQVFPVMPLHRLWNKPERRGQLVDLTCDSDGKVSQYVTSSGTSDWLPLHNFRQDESYYLGIFLVGAYQEILGDAHNL
FGRVGEVHVYAKAEEANGFWIEALLKGISVKEMLSQVQYFPNDLDRRMSEFIRRQINAGRIKPAEGTRILNNYTQRLGDT
TYCDVSSNEPLS

Sequences:

>Translated_652_residues
MTNEAVAKHDWSCEDSQALYAMSKWGDGFYSVNKMGHVSVRPIEGQDLHIDIIDVIQSARSEGASLPMLIRFQDVISSRV
RRLNQTFRKAIHESGYEGTYRSIYPIKVNQLQEVVAEVLEAGQEFNIGLECGSKAELLAMLPLVADETLLLCNGVKDRTM
LTLMLNAQQIGQQVMPIIEKYSEFEQLMNLAEARQMKPRLGVRLKLNTKGSGRWFESGGANSKFGLTISELVQLIRTLEN
REMAGQLELLHFHLGSQIADIQVLRSAIREIMQVYADLMLRGMQIKYLDVGGGLGVNYGGDYDNPESSINYGLREYANVV
VYTVKEICDQRQVPMPQLLSESGRALTAHHSVLVVPVLGVHKPDSPYMAESPAELPAVVLRMTSVYSDAQSAEKMSTLLE
CYHDAQEIRQETEQMARLGYLSVEHMAQSDSLYWSICREVLRKLTAIGSIPVTAEQIELEKQLTDMYLGDFSVFHSIIDH
WAIGQVFPVMPLHRLWNKPERRGQLVDLTCDSDGKVSQYVTSSGTSDWLPLHNFRQDESYYLGIFLVGAYQEILGDAHNL
FGRVGEVHVYAKAEEANGFWIEALLKGISVKEMLSQVQYFPNDLDRRMSEFIRRQINAGRIKPAEGTRILNNYTQRLGDT
TYCDVSSNEPLS
>Mature_651_residues
TNEAVAKHDWSCEDSQALYAMSKWGDGFYSVNKMGHVSVRPIEGQDLHIDIIDVIQSARSEGASLPMLIRFQDVISSRVR
RLNQTFRKAIHESGYEGTYRSIYPIKVNQLQEVVAEVLEAGQEFNIGLECGSKAELLAMLPLVADETLLLCNGVKDRTML
TLMLNAQQIGQQVMPIIEKYSEFEQLMNLAEARQMKPRLGVRLKLNTKGSGRWFESGGANSKFGLTISELVQLIRTLENR
EMAGQLELLHFHLGSQIADIQVLRSAIREIMQVYADLMLRGMQIKYLDVGGGLGVNYGGDYDNPESSINYGLREYANVVV
YTVKEICDQRQVPMPQLLSESGRALTAHHSVLVVPVLGVHKPDSPYMAESPAELPAVVLRMTSVYSDAQSAEKMSTLLEC
YHDAQEIRQETEQMARLGYLSVEHMAQSDSLYWSICREVLRKLTAIGSIPVTAEQIELEKQLTDMYLGDFSVFHSIIDHW
AIGQVFPVMPLHRLWNKPERRGQLVDLTCDSDGKVSQYVTSSGTSDWLPLHNFRQDESYYLGIFLVGAYQEILGDAHNLF
GRVGEVHVYAKAEEANGFWIEALLKGISVKEMLSQVQYFPNDLDRRMSEFIRRQINAGRIKPAEGTRILNNYTQRLGDTT
YCDVSSNEPLS

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=599, Percent_Identity=36.3939899833055, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 73496; Mature: 73365

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEAVAKHDWSCEDSQALYAMSKWGDGFYSVNKMGHVSVRPIEGQDLHIDIIDVIQSAR
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCEEEECCCCCCEEEHHHHHHHHHH
SEGASLPMLIRFQDVISSRVRRLNQTFRKAIHESGYEGTYRSIYPIKVNQLQEVVAEVLE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECEEHHHHHHHHHHHHH
AGQEFNIGLECGSKAELLAMLPLVADETLLLCNGVKDRTMLTLMLNAQQIGQQVMPIIEK
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHH
YSEFEQLMNLAEARQMKPRLGVRLKLNTKGSGRWFESGGANSKFGLTISELVQLIRTLEN
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHC
REMAGQLELLHFHLGSQIADIQVLRSAIREIMQVYADLMLRGMQIKYLDVGGGLGVNYGG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
DYDNPESSINYGLREYANVVVYTVKEICDQRQVPMPQLLSESGRALTAHHSVLVVPVLGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCEEEEEEECC
HKPDSPYMAESPAELPAVVLRMTSVYSDAQSAEKMSTLLECYHDAQEIRQETEQMARLGY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVEHMAQSDSLYWSICREVLRKLTAIGSIPVTAEQIELEKQLTDMYLGDFSVFHSIIDH
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAIGQVFPVMPLHRLWNKPERRGQLVDLTCDSDGKVSQYVTSSGTSDWLPLHNFRQDESY
HHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCE
YLGIFLVGAYQEILGDAHNLFGRVGEVHVYAKAEEANGFWIEALLKGISVKEMLSQVQYF
EEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCHHHHHHHHHHC
PNDLDRRMSEFIRRQINAGRIKPAEGTRILNNYTQRLGDTTYCDVSSNEPLS
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure 
TNEAVAKHDWSCEDSQALYAMSKWGDGFYSVNKMGHVSVRPIEGQDLHIDIIDVIQSAR
CCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCEEEECCCCCCEEEHHHHHHHHHH
SEGASLPMLIRFQDVISSRVRRLNQTFRKAIHESGYEGTYRSIYPIKVNQLQEVVAEVLE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECEEHHHHHHHHHHHHH
AGQEFNIGLECGSKAELLAMLPLVADETLLLCNGVKDRTMLTLMLNAQQIGQQVMPIIEK
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHH
YSEFEQLMNLAEARQMKPRLGVRLKLNTKGSGRWFESGGANSKFGLTISELVQLIRTLEN
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHC
REMAGQLELLHFHLGSQIADIQVLRSAIREIMQVYADLMLRGMQIKYLDVGGGLGVNYGG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
DYDNPESSINYGLREYANVVVYTVKEICDQRQVPMPQLLSESGRALTAHHSVLVVPVLGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCEEEEEEECC
HKPDSPYMAESPAELPAVVLRMTSVYSDAQSAEKMSTLLECYHDAQEIRQETEQMARLGY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVEHMAQSDSLYWSICREVLRKLTAIGSIPVTAEQIELEKQLTDMYLGDFSVFHSIIDH
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAIGQVFPVMPLHRLWNKPERRGQLVDLTCDSDGKVSQYVTSSGTSDWLPLHNFRQDESY
HHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCE
YLGIFLVGAYQEILGDAHNLFGRVGEVHVYAKAEEANGFWIEALLKGISVKEMLSQVQYF
EEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCHHHHHHHHHHC
PNDLDRRMSEFIRRQINAGRIKPAEGTRILNNYTQRLGDTTYCDVSSNEPLS
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA