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The map label for this gene is rnpA

Identifier: 114332117

GI number: 114332117

Start: 2278061

End: 2278426

Strand: Direct

Name: rnpA

Synonym: Neut_2152

Alternate gene names: 114332117

Gene position: 2278061-2278426 (Clockwise)

Preceding gene: 114332116

Following gene: 114332118

Centisome position: 85.61

GC content: 48.09

Gene sequence:

>366_bases
TTGACAACCGAGCATGTTTACTCGTTACCCAAATCGTGCAGACTGCGAAAAGCTGATGAATTTCGCGCTGTACTGAGACA
TCGGACTGTGTTCGAAAGCCTTTCTTTGCGATTGCATATAAAGCTGAAGCCGATCAACGACGGTTATGCGCGCATCGGCT
TAATCGTAGCCAAAAAGATCGAGCGGAAAGCTGTCAGAAGAAACCGCATCAAACGATTGATCAGAGAGGCATTTCGCAAG
CACAGACAGGTGGTTCAAGGTATGGATTGCGTTATGCAGCTACGGCGTTCTGTGGAACCGTCAGATTCTGCGCGCATCTA
TCAGGAAGCCGTAACGCTGTTACATAAAGCAGCCAGGCAATTATGA

Upstream 100 bases:

>100_bases
ACGTGGTGGCAGAGCTGTTATTCGTGCACGCCGGGCAAAGGGACGGGTCAGACTCAGTGTATAACATGGACAAATCCAGG
TTTACTGTCCGAGCTGTTTC

Downstream 100 bases:

>100_bases
AGCAACTGATCATTGGCCTTATTAAACTCTACCAATACAGCATCGGCCTCCTGATTCCACCTTCCTGCAGATTTTACCCA
ACCTGCTCGAATTATATGCG

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MTTEHVYSLPKSCRLRKADEFRAVLRHRTVFESLSLRLHIKLKPINDGYARIGLIVAKKIERKAVRRNRIKRLIREAFRK
HRQVVQGMDCVMQLRRSVEPSDSARIYQEAVTLLHKAARQL

Sequences:

>Translated_121_residues
MTTEHVYSLPKSCRLRKADEFRAVLRHRTVFESLSLRLHIKLKPINDGYARIGLIVAKKIERKAVRRNRIKRLIREAFRK
HRQVVQGMDCVMQLRRSVEPSDSARIYQEAVTLLHKAARQL
>Mature_120_residues
TTEHVYSLPKSCRLRKADEFRAVLRHRTVFESLSLRLHIKLKPINDGYARIGLIVAKKIERKAVRRNRIKRLIREAFRKH
RQVVQGMDCVMQLRRSVEPSDSARIYQEAVTLLHKAARQL

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_NITEC (Q0AE58)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748339.1
- ProteinModelPortal:   Q0AE58
- SMR:   Q0AE58
- STRING:   Q0AE58
- GeneID:   4272940
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2152
- NMPDR:   fig|335283.3.peg.186
- eggNOG:   NOG127496
- HOGENOM:   HBG728160
- OMA:   DCVMQLR
- ProtClustDB:   CLSK585298
- BioCyc:   NEUT335283:NEUT_2152-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 14272; Mature: 14141

Theoretical pI: Translated: 11.78; Mature: 11.78

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEHVYSLPKSCRLRKADEFRAVLRHRTVFESLSLRLHIKLKPINDGYARIGLIVAKKI
CCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHH
ERKAVRRNRIKRLIREAFRKHRQVVQGMDCVMQLRRSVEPSDSARIYQEAVTLLHKAARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
TTEHVYSLPKSCRLRKADEFRAVLRHRTVFESLSLRLHIKLKPINDGYARIGLIVAKKI
CCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHH
ERKAVRRNRIKRLIREAFRKHRQVVQGMDCVMQLRRSVEPSDSARIYQEAVTLLHKAARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA