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The map label for this gene is pgsA [H]

Identifier: 114332045

GI number: 114332045

Start: 2200535

End: 2201107

Strand: Reverse

Name: pgsA [H]

Synonym: Neut_2079

Alternate gene names: 114332045

Gene position: 2201107-2200535 (Counterclockwise)

Preceding gene: 114332046

Following gene: 114332044

Centisome position: 82.72

GC content: 45.38

Gene sequence:

>573_bases
ATGCTGATGAATCTTCCCAATTCTTTGACGTGGCTGCGCATAATGGCTATTCCTCTGTTTGTTGGTATTTTTTACCTGCC
ATCAGAATGGTTGTCTCCAGCCGCGCAAAACTTGGTTGCAGCTATTGTATTTGGGGGGGCCGCATTGACTGATTGGCTGG
ATGGCTACTTGGCCCGAGCACTCAATCAAACTTCCGCATTTGGTGCTTTTCTTGATCCGGTGGCTGACAAGTTGATGGTA
GCTGCTGCGCTGATTGTTTTGGTACATTTGGATCGGCTTGATGTATCGATCGCATTGATTATCATTGGCCGCGAAATTAC
TATTTCTGCTCTGCGTGAATGGATGGCGCAAATTGGCAAATCTAAAAGTGTGGCGGTTTCCTTTTTGGGCAAGATCAAGA
CAGCTGCGCAAATGGTGGCAATTCCTCTATTGCTTTACCATGATAGGGTTCATGATTCATTCGATTCACAAATGATTGGC
ACCTGGTTGATTTATATTGCCGCCATTTTGACATTGTGGTCCATGGTCTACTATTTGAGAGCTGCTATTCCACACGCTAC
TCATCGTCATTGA

Upstream 100 bases:

>100_bases
GTAAGTCGTGATTACTCTGGGTAGAGAGAACGTCTGTAGTAAATTATAAATATCTGCCTACTAATGTGATGGGCTGAAAC
AGATTGGAGTGCTTTTGGTT

Downstream 100 bases:

>100_bases
AGAAATTTTCATCAATAATAAGGTATCCCGCCATGTAAACGGGGGTAGTTGATTAAGATTTCAGAAAAAATAAAACAAAA
GAGAATCTGCTTGCCGCCAA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MLMNLPNSLTWLRIMAIPLFVGIFYLPSEWLSPAAQNLVAAIVFGGAALTDWLDGYLARALNQTSAFGAFLDPVADKLMV
AAALIVLVHLDRLDVSIALIIIGREITISALREWMAQIGKSKSVAVSFLGKIKTAAQMVAIPLLLYHDRVHDSFDSQMIG
TWLIYIAAILTLWSMVYYLRAAIPHATHRH

Sequences:

>Translated_190_residues
MLMNLPNSLTWLRIMAIPLFVGIFYLPSEWLSPAAQNLVAAIVFGGAALTDWLDGYLARALNQTSAFGAFLDPVADKLMV
AAALIVLVHLDRLDVSIALIIIGREITISALREWMAQIGKSKSVAVSFLGKIKTAAQMVAIPLLLYHDRVHDSFDSQMIG
TWLIYIAAILTLWSMVYYLRAAIPHATHRH
>Mature_190_residues
MLMNLPNSLTWLRIMAIPLFVGIFYLPSEWLSPAAQNLVAAIVFGGAALTDWLDGYLARALNQTSAFGAFLDPVADKLMV
AAALIVLVHLDRLDVSIALIIIGREITISALREWMAQIGKSKSVAVSFLGKIKTAAQMVAIPLLLYHDRVHDSFDSQMIG
TWLIYIAAILTLWSMVYYLRAAIPHATHRH

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=184, Percent_Identity=51.6304347826087, Blast_Score=166, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6320059, Length=215, Percent_Identity=32.5581395348837, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21001; Mature: 21001

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMNLPNSLTWLRIMAIPLFVGIFYLPSEWLSPAAQNLVAAIVFGGAALTDWLDGYLARA
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQTSAFGAFLDPVADKLMVAAALIVLVHLDRLDVSIALIIIGREITISALREWMAQIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHCC
SKSVAVSFLGKIKTAAQMVAIPLLLYHDRVHDSFDSQMIGTWLIYIAAILTLWSMVYYLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIPHATHRH
HHCCCCCCCC
>Mature Secondary Structure
MLMNLPNSLTWLRIMAIPLFVGIFYLPSEWLSPAAQNLVAAIVFGGAALTDWLDGYLARA
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQTSAFGAFLDPVADKLMVAAALIVLVHLDRLDVSIALIIIGREITISALREWMAQIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHCC
SKSVAVSFLGKIKTAAQMVAIPLLLYHDRVHDSFDSQMIGTWLIYIAAILTLWSMVYYLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIPHATHRH
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]