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The map label for this gene is cmpB [H]

Identifier: 114332018

GI number: 114332018

Start: 2168699

End: 2169535

Strand: Direct

Name: cmpB [H]

Synonym: Neut_2052

Alternate gene names: 114332018

Gene position: 2168699-2169535 (Clockwise)

Preceding gene: 114332017

Following gene: 114332019

Centisome position: 81.5

GC content: 51.14

Gene sequence:

>837_bases
ATGAAACCTCATGTTTCAGAAAAATCCGGTCACCAGCTCACGCTAACTGGCCGGGTTAGCCAACTGCTTTTTAAATCAAA
TTTCCTGTGGTTTTGTCTGGCCTGGTTGCTGATCATTCTATCCTGGGAGCTTGGTTCCTGGCTGGAATGGTTAAATCCGC
AAATTCTGCCCCCTCCTAGTGAAACTATTCCGTATGCCTTTTCCGGCAACATCACCATCGGGTTCGGTCAGCAGAAAACC
GGGTTGTTTGAGTCTACTACCATCACGCTGGGGCGCGTGGGTGCCGGTATGCTGATCGGCCTCCTGGTTTCATCCTGCCT
CGCTATCATGGTGATTGAGCTGCCCATTTTGCGACGATTGATCTTGCCCCTTGTCCAGTCGCTTGCACCTATCGCACCGG
TGGCCTGGATCCCTTTCACCATCGTTGTTATTGGTATTGGTGGCCCAGCCGCTGTATTCATCGTATTCATGGCAGTACTC
GGAACCATGACGCTCTCGCTAATTGCCGCACTAGATAGCATCCCGGATGAATATCTGAAAATCGCCCATAATTTGGGTAC
CTCACGCATCCGTATGTGGTGGTATATACGGCTGCCCGCCATCATCCCCAGCACAATGACAGCCATTCGCATGTCGTTCT
TCGGTGCCTGGATGGCTGTTCTGGCAGGAGAAATGGCTGGCCTCAACTCCGGCCTGGGGTACATGATCATCATGGCGCAG
CAGATGTACAACATGAAATTAGTCATGGTCGGCATTCTCGCCATTGGCTTCATTGGTTTTGCCATTGATCGCCTGTTATT
GCTGATCAATGCCAGACTATTGCAATGGGTGCAGTAA

Upstream 100 bases:

>100_bases
GGCCTGCGTCAGGGAGCAAAATATCTGACCGAACTGGGTTATCTGAAGCCGGATGTCATTGATACCGTTCTGGATCTGCA
ATACCAGCCGGCCTGACGCC

Downstream 100 bases:

>100_bases
ATCCATGAACACAATACCTTCTTCCTCATCCGGCGCTCGGCTAGAATTCAGTAACATCCGTAAATCCTTCAGCGATACTG
TTTCTGTAGAAGCAGATAGG

Product: binding-protein-dependent transport systems inner membrane component

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKPHVSEKSGHQLTLTGRVSQLLFKSNFLWFCLAWLLIILSWELGSWLEWLNPQILPPPSETIPYAFSGNITIGFGQQKT
GLFESTTITLGRVGAGMLIGLLVSSCLAIMVIELPILRRLILPLVQSLAPIAPVAWIPFTIVVIGIGGPAAVFIVFMAVL
GTMTLSLIAALDSIPDEYLKIAHNLGTSRIRMWWYIRLPAIIPSTMTAIRMSFFGAWMAVLAGEMAGLNSGLGYMIIMAQ
QMYNMKLVMVGILAIGFIGFAIDRLLLLINARLLQWVQ

Sequences:

>Translated_278_residues
MKPHVSEKSGHQLTLTGRVSQLLFKSNFLWFCLAWLLIILSWELGSWLEWLNPQILPPPSETIPYAFSGNITIGFGQQKT
GLFESTTITLGRVGAGMLIGLLVSSCLAIMVIELPILRRLILPLVQSLAPIAPVAWIPFTIVVIGIGGPAAVFIVFMAVL
GTMTLSLIAALDSIPDEYLKIAHNLGTSRIRMWWYIRLPAIIPSTMTAIRMSFFGAWMAVLAGEMAGLNSGLGYMIIMAQ
QMYNMKLVMVGILAIGFIGFAIDRLLLLINARLLQWVQ
>Mature_278_residues
MKPHVSEKSGHQLTLTGRVSQLLFKSNFLWFCLAWLLIILSWELGSWLEWLNPQILPPPSETIPYAFSGNITIGFGQQKT
GLFESTTITLGRVGAGMLIGLLVSSCLAIMVIELPILRRLILPLVQSLAPIAPVAWIPFTIVVIGIGGPAAVFIVFMAVL
GTMTLSLIAALDSIPDEYLKIAHNLGTSRIRMWWYIRLPAIIPSTMTAIRMSFFGAWMAVLAGEMAGLNSGLGYMIIMAQ
QMYNMKLVMVGILAIGFIGFAIDRLLLLINARLLQWVQ

Specific function: Part of the ABC transporter complex CmpABCD involved in bicarbonate transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=229, Percent_Identity=24.4541484716157, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081802, Length=240, Percent_Identity=25.4166666666667, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005889 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30615; Mature: 30615

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50928 ABC_TM1 ; PS00457 NA_SOLUT_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPHVSEKSGHQLTLTGRVSQLLFKSNFLWFCLAWLLIILSWELGSWLEWLNPQILPPPS
CCCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ETIPYAFSGNITIGFGQQKTGLFESTTITLGRVGAGMLIGLLVSSCLAIMVIELPILRRL
CCCCEEEECCEEEECCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILPLVQSLAPIAPVAWIPFTIVVIGIGGPAAVFIVFMAVLGTMTLSLIAALDSIPDEYLK
HHHHHHHHCCCCHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IAHNLGTSRIRMWWYIRLPAIIPSTMTAIRMSFFGAWMAVLAGEMAGLNSGLGYMIIMAQ
HHHHCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QMYNMKLVMVGILAIGFIGFAIDRLLLLINARLLQWVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPHVSEKSGHQLTLTGRVSQLLFKSNFLWFCLAWLLIILSWELGSWLEWLNPQILPPPS
CCCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ETIPYAFSGNITIGFGQQKTGLFESTTITLGRVGAGMLIGLLVSSCLAIMVIELPILRRL
CCCCEEEECCEEEECCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILPLVQSLAPIAPVAWIPFTIVVIGIGGPAAVFIVFMAVLGTMTLSLIAALDSIPDEYLK
HHHHHHHHCCCCHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IAHNLGTSRIRMWWYIRLPAIIPSTMTAIRMSFFGAWMAVLAGEMAGLNSGLGYMIIMAQ
HHHHCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QMYNMKLVMVGILAIGFIGFAIDRLLLLINARLLQWVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]