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The map label for this gene is cdsA [H]

Identifier: 114331996

GI number: 114331996

Start: 2146313

End: 2147140

Strand: Reverse

Name: cdsA [H]

Synonym: Neut_2030

Alternate gene names: 114331996

Gene position: 2147140-2146313 (Counterclockwise)

Preceding gene: 114331997

Following gene: 114331995

Centisome position: 80.69

GC content: 47.34

Gene sequence:

>828_bases
ATGCTTAGCACCCGACTCTTTACCGCACTCATATTATTGACCGCCTTTCTGGCGGCATTATTTTATCTACCGGATATTTT
CTGGGCAGTATTACTCCTGGGATTGACTGTTACAGCAGCCAGAGAGTGGTGCCGTCTGGGGCGTTTCTCAATTGGCCAGA
CTGTTCTTTATATGATTTTTACCACCTTGCTGGGAGGGGAGCTATTATTCCTGACCAGCATGGCGGTAGCCAGAAATCCG
GCAGATTCATCGATGATCTGGTTTTATATTGCATCTGCCATCTTCTGGCTGTTAGCGGTACCTTACCAATTGGTAACAAT
CCAACCCATCCGCAATGTGTGGGTATTCATGTTAACCGGCTGGCTGGTATTGCTGCCGGCGTGTCTGTCACTATATCAGC
TTCGTGCGATGGATCCATTATTGTTACTTGGATTCATGGGAGTAGTGTGGGTATCTGACAGCGTTGCTTATTTTATCGGG
CGTACCTATGGCAAGCATAAACTTGCCCCGCAGATCAGTCCTGGAAAGACGTGGGAGGGAGTGGCTGCTGCGCTAGTTGG
CGTATTGATCTATGCATTGATCTGGTTTTGCATAGTAGATAGAGAAAACAAGCTGATTAGCTTGCTGGTTCCTTTATTGC
TTGTGCTCGCGGTGCTGGGAATAGTGGGTGATCTGTTTGAATCACTGTTGAAACGGCAGGCAGGCGTTAAGGATAGTGGC
AATATTCTGCCAGGTCACGGCGGTATACTGGATCGTATTGATGCGTTGATCCCAGTTTTACCTGTTGCTGCGCTATCGGC
CATCTTATTTTATTCGACTGAATTATGA

Upstream 100 bases:

>100_bases
ACAAGTGAGCAGCTTGCAAGTCGGCAGGAAATCAAGGATACGATCTTGAACGAAAATAAAGTTTAACCATCATTGTTCAA
TTAACGGGACTCACCCGTTC

Downstream 100 bases:

>100_bases
CTCCAATCCGTCATCTGACCATCTTGGGCTCGACCGGCAGCATTGGGGAAAGCACATTGGACGTGGTAGCCAGACATCCC
GACCGGTTTCAGGCGGTTGC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLSTRLFTALILLTAFLAALFYLPDIFWAVLLLGLTVTAAREWCRLGRFSIGQTVLYMIFTTLLGGELLFLTSMAVARNP
ADSSMIWFYIASAIFWLLAVPYQLVTIQPIRNVWVFMLTGWLVLLPACLSLYQLRAMDPLLLLGFMGVVWVSDSVAYFIG
RTYGKHKLAPQISPGKTWEGVAAALVGVLIYALIWFCIVDRENKLISLLVPLLLVLAVLGIVGDLFESLLKRQAGVKDSG
NILPGHGGILDRIDALIPVLPVAALSAILFYSTEL

Sequences:

>Translated_275_residues
MLSTRLFTALILLTAFLAALFYLPDIFWAVLLLGLTVTAAREWCRLGRFSIGQTVLYMIFTTLLGGELLFLTSMAVARNP
ADSSMIWFYIASAIFWLLAVPYQLVTIQPIRNVWVFMLTGWLVLLPACLSLYQLRAMDPLLLLGFMGVVWVSDSVAYFIG
RTYGKHKLAPQISPGKTWEGVAAALVGVLIYALIWFCIVDRENKLISLLVPLLLVLAVLGIVGDLFESLLKRQAGVKDSG
NILPGHGGILDRIDALIPVLPVAALSAILFYSTEL
>Mature_275_residues
MLSTRLFTALILLTAFLAALFYLPDIFWAVLLLGLTVTAAREWCRLGRFSIGQTVLYMIFTTLLGGELLFLTSMAVARNP
ADSSMIWFYIASAIFWLLAVPYQLVTIQPIRNVWVFMLTGWLVLLPACLSLYQLRAMDPLLLLGFMGVVWVSDSVAYFIG
RTYGKHKLAPQISPGKTWEGVAAALVGVLIYALIWFCIVDRENKLISLLVPLLLVLAVLGIVGDLFESLLKRQAGVKDSG
NILPGHGGILDRIDALIPVLPVAALSAILFYSTEL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=285, Percent_Identity=34.3859649122807, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787677, Length=111, Percent_Identity=44.1441441441441, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30322; Mature: 30322

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTRLFTALILLTAFLAALFYLPDIFWAVLLLGLTVTAAREWCRLGRFSIGQTVLYMIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TTLLGGELLFLTSMAVARNPADSSMIWFYIASAIFWLLAVPYQLVTIQPIRNVWVFMLTG
HHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLVLLPACLSLYQLRAMDPLLLLGFMGVVWVSDSVAYFIGRTYGKHKLAPQISPGKTWEG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VAAALVGVLIYALIWFCIVDRENKLISLLVPLLLVLAVLGIVGDLFESLLKRQAGVKDSG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NILPGHGGILDRIDALIPVLPVAALSAILFYSTEL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSTRLFTALILLTAFLAALFYLPDIFWAVLLLGLTVTAAREWCRLGRFSIGQTVLYMIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TTLLGGELLFLTSMAVARNPADSSMIWFYIASAIFWLLAVPYQLVTIQPIRNVWVFMLTG
HHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLVLLPACLSLYQLRAMDPLLLLGFMGVVWVSDSVAYFIGRTYGKHKLAPQISPGKTWEG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VAAALVGVLIYALIWFCIVDRENKLISLLVPLLLVLAVLGIVGDLFESLLKRQAGVKDSG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NILPGHGGILDRIDALIPVLPVAALSAILFYSTEL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]