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The map label for this gene is atpB2 [H]

Identifier: 114331983

GI number: 114331983

Start: 2131471

End: 2132163

Strand: Direct

Name: atpB2 [H]

Synonym: Neut_2017

Alternate gene names: 114331983

Gene position: 2131471-2132163 (Clockwise)

Preceding gene: 114331982

Following gene: 114331984

Centisome position: 80.1

GC content: 45.17

Gene sequence:

>693_bases
ATGCAGCTCACACCAGACCAAACAGTAGTGTTTACTTTAGGACAGTGGCAGGTTAACGCCACTATCGTTAATACTTGGAT
TGTGATGATACTGTTGGCTGGCATTTCGATGCTGGTGACTCGCAATCTACGTGCTGACAAAGCACCTGGGCGCTGGCGCA
GTGCTTTAGAACTGATTGTCACTATGATTCAAGGGCAAATTGAAGAGGTAACCCGCAGCAGTGCACGGCATGTATTGTAT
TTTGCCGGTACTTTATTTCTCTTTATAGCTGCGTCCAATGTGCTAACAGTTATTCCAGGCTTTGTTCCGCCCACTTCATC
GTTATCAACTACGGTTGCGCTAACCTTGTCGGTGTTAGTCGCGATTCCTTTGTTTGGAATTGCCAAGGGGGGGGTGCGCC
AATACTTACGCAAATTTATTGAACCGTCGATGATTATGCTGCCATTTAATATCATTGGTGAATTTTCTCGAGGCGTATCT
TTAGCGATCCGTCTGTATGGAAACGTGATGAGCGGTGTGGTGATTGCAGCTATTTTACTCAGTATTGCACCATTCTTTTT
TCCTGTGGTAATGGATATGCTGGGCCTGCTAACCGGCTTTATTCAGGCCTACATCTTTGCCATTTTAGCCACTGTGTATA
TTTCATCTGCCATGGCAGATCCTCCCCTGGATACATCTGATAAGGATAAATAA

Upstream 100 bases:

>100_bases
AGCTGGTTATATGTTGGCTTTTGTACTGATGCGCGTACTGGCAGTGGTACGAGCGCAGTTGACCCACAGCGTCACCTAAT
CAAAACACGAAGGTATATAA

Downstream 100 bases:

>100_bases
TCATGACTGATCTTGCACTGATTGCCGCTATTTCTATTTTTACTGCTGGCCTAACCATCGCGATTGGCTCGCTAGGGCCC
GCGCTAGGTGAAGGACGTGC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 2; F-ATPase subunit 6 2 [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MQLTPDQTVVFTLGQWQVNATIVNTWIVMILLAGISMLVTRNLRADKAPGRWRSALELIVTMIQGQIEEVTRSSARHVLY
FAGTLFLFIAASNVLTVIPGFVPPTSSLSTTVALTLSVLVAIPLFGIAKGGVRQYLRKFIEPSMIMLPFNIIGEFSRGVS
LAIRLYGNVMSGVVIAAILLSIAPFFFPVVMDMLGLLTGFIQAYIFAILATVYISSAMADPPLDTSDKDK

Sequences:

>Translated_230_residues
MQLTPDQTVVFTLGQWQVNATIVNTWIVMILLAGISMLVTRNLRADKAPGRWRSALELIVTMIQGQIEEVTRSSARHVLY
FAGTLFLFIAASNVLTVIPGFVPPTSSLSTTVALTLSVLVAIPLFGIAKGGVRQYLRKFIEPSMIMLPFNIIGEFSRGVS
LAIRLYGNVMSGVVIAAILLSIAPFFFPVVMDMLGLLTGFIQAYIFAILATVYISSAMADPPLDTSDKDK
>Mature_230_residues
MQLTPDQTVVFTLGQWQVNATIVNTWIVMILLAGISMLVTRNLRADKAPGRWRSALELIVTMIQGQIEEVTRSSARHVLY
FAGTLFLFIAASNVLTVIPGFVPPTSSLSTTVALTLSVLVAIPLFGIAKGGVRQYLRKFIEPSMIMLPFNIIGEFSRGVS
LAIRLYGNVMSGVVIAAILLSIAPFFFPVVMDMLGLLTGFIQAYIFAILATVYISSAMADPPLDTSDKDK

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=199, Percent_Identity=22.6130653266332, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017692
- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 25030; Mature: 25030

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTPDQTVVFTLGQWQVNATIVNTWIVMILLAGISMLVTRNLRADKAPGRWRSALELIV
CCCCCCCEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TMIQGQIEEVTRSSARHVLYFAGTLFLFIAASNVLTVIPGFVPPTSSLSTTVALTLSVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AIPLFGIAKGGVRQYLRKFIEPSMIMLPFNIIGEFSRGVSLAIRLYGNVMSGVVIAAILL
HHHHHHHCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIAPFFFPVVMDMLGLLTGFIQAYIFAILATVYISSAMADPPLDTSDKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQLTPDQTVVFTLGQWQVNATIVNTWIVMILLAGISMLVTRNLRADKAPGRWRSALELIV
CCCCCCCEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TMIQGQIEEVTRSSARHVLYFAGTLFLFIAASNVLTVIPGFVPPTSSLSTTVALTLSVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AIPLFGIAKGGVRQYLRKFIEPSMIMLPFNIIGEFSRGVSLAIRLYGNVMSGVVIAAILL
HHHHHHHCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIAPFFFPVVMDMLGLLTGFIQAYIFAILATVYISSAMADPPLDTSDKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA