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The map label for this gene is bcsA [H]

Identifier: 114331946

GI number: 114331946

Start: 2090741

End: 2092219

Strand: Reverse

Name: bcsA [H]

Synonym: Neut_1975

Alternate gene names: 114331946

Gene position: 2092219-2090741 (Counterclockwise)

Preceding gene: 114331947

Following gene: 114331945

Centisome position: 78.62

GC content: 47.8

Gene sequence:

>1479_bases
ATGCTGATGCTGACTGTGCTTTCCTATGCAGCCCAGGCTGTTTTCTTTCTGGTGGTGGTTTGTTTTATCTTGTATGTACT
GCTGGAATTGCGCGTACTGGGGATTTCACGTCGGGTTGAGCGTCACAAACTGACGGAGCTGGTTTCCCAATTACCTGGTA
TGTTGGCATTGCCCGTCTGGCCACGGGTCAGCGTGCTGCTGCCTATCTACAATGAAGCAGCAGTGATAGTGCGTCTGATT
GATGCAGTTTGTCGGCTGCAATATCCAACTTCCTCTCTTGAAATTCTGGTGCTGGATGATTCAACAGATAATACTTCAAC
GCTTGCCCAGGCACGGATTGACTATCATGCGGATTTAGGAGTTTCGATTCGTTACGTCCGGCGTGCGAGCAATGAGGGCT
ACAAGGCAGGCAATCTGCTCAATGGTATTCGCCAGTCATCCGGTGAGTTTTATGTAATTTTTGATGCTGATTTTATACCC
CAGGAAGATTTTCTGCTCAGGACTGTTCCTTATTTTCAGGATCCACAGTTGGGGTTTTTGCAAACCGGGATCGGCTATGA
AAATCGTGACGCTTCTTTTTTGACCCGCTTTCAGGCCATGGAAATGGGGCACCAGCAGTATGTTACGGTGGGTTTGAGCG
AAGATGGAGACATGGCTTCTCTTTCCGGCAGTTCCTGTGTGTGGCGCAGAGCCTGTGTTGAATCCCTGGGAGGATGGAAT
GCATCCACAGTGACCGAGGATGTGGATTTAGGCTATCGGGCTCAGTTTGGAAACTGGAAATATGCTTATATGCGTGACGT
GGTGTCAATGTCGGTGTTGCCTGAAACGACCAGTGCCTTCCGGGTTCAGCGGAAGCGCTGGGGCAGGGGATTGATTCACA
GCGCTTTCAAGCACGCGCGGCAGATGTTCCGGCAACGTATGCCATTGATGCAACGTTTGCATGCGATCGCCATGATGTTT
TCATCACTGTTGCTGGCATCCATTTATATATTGCTGCTGTTGTGTTTACCACTGAGTTATCTGGTTGATTTTGAAGGATT
GGGAATCCATTGGGTAGCTTGGCTTTTTTTTGGTTTTGTAGCGATATGGGGGCTGAATAATGTATTTGCCGCACGTAAGG
GAGCTCACATTGGGGAACAACGGGGTATTTTGCGCACTTTGTGGGAAACCTATCTTTACGTTGCTATGTTTTTGCCCATG
GCGTGGTATTACTTTGCTGGTGGAATGCGTGCGTTGTTTGGAGTGCATGGTGATTTTCATCGTACGCTCAAGGGGGGAAG
CAAAAAAAGTGTTATCAGACCACCCGTCCATAAAATTTTGTGGATGGGAGATGGGTTTTCATTTGGTTATTCTGCAATAA
CTTTGTGGGTGGCAATCCAGAAGGCAAATTACTTTCTGATTCCGATCAGCGTGACGGCTTGTCTGGGTTTTGGCATGATG
CTGGTTGGTTTTTGGCAAGAAGAACGTTCAATCAAATAA

Upstream 100 bases:

>100_bases
GATGACATGGCGCGTGCGGAAGCAGGTGCACGCTATGTACGCAAACATCATACCTGGGCGCATCGGCTGGGTGAGCTTGG
CAGTGTCGTGAAGTTTTAGG

Downstream 100 bases:

>100_bases
ATGACTGAGATTAAAAATGATACCGGGATGCCGCAGGAATTCAGGAGAACAATTAACCTGGAGCAGTGTGATAAACGGGT
ATTGATTACGGGAGCGACCA

Product: cellulose synthase (UDP-forming)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLMLTVLSYAAQAVFFLVVVCFILYVLLELRVLGISRRVERHKLTELVSQLPGMLALPVWPRVSVLLPIYNEAAVIVRLI
DAVCRLQYPTSSLEILVLDDSTDNTSTLAQARIDYHADLGVSIRYVRRASNEGYKAGNLLNGIRQSSGEFYVIFDADFIP
QEDFLLRTVPYFQDPQLGFLQTGIGYENRDASFLTRFQAMEMGHQQYVTVGLSEDGDMASLSGSSCVWRRACVESLGGWN
ASTVTEDVDLGYRAQFGNWKYAYMRDVVSMSVLPETTSAFRVQRKRWGRGLIHSAFKHARQMFRQRMPLMQRLHAIAMMF
SSLLLASIYILLLLCLPLSYLVDFEGLGIHWVAWLFFGFVAIWGLNNVFAARKGAHIGEQRGILRTLWETYLYVAMFLPM
AWYYFAGGMRALFGVHGDFHRTLKGGSKKSVIRPPVHKILWMGDGFSFGYSAITLWVAIQKANYFLIPISVTACLGFGMM
LVGFWQEERSIK

Sequences:

>Translated_492_residues
MLMLTVLSYAAQAVFFLVVVCFILYVLLELRVLGISRRVERHKLTELVSQLPGMLALPVWPRVSVLLPIYNEAAVIVRLI
DAVCRLQYPTSSLEILVLDDSTDNTSTLAQARIDYHADLGVSIRYVRRASNEGYKAGNLLNGIRQSSGEFYVIFDADFIP
QEDFLLRTVPYFQDPQLGFLQTGIGYENRDASFLTRFQAMEMGHQQYVTVGLSEDGDMASLSGSSCVWRRACVESLGGWN
ASTVTEDVDLGYRAQFGNWKYAYMRDVVSMSVLPETTSAFRVQRKRWGRGLIHSAFKHARQMFRQRMPLMQRLHAIAMMF
SSLLLASIYILLLLCLPLSYLVDFEGLGIHWVAWLFFGFVAIWGLNNVFAARKGAHIGEQRGILRTLWETYLYVAMFLPM
AWYYFAGGMRALFGVHGDFHRTLKGGSKKSVIRPPVHKILWMGDGFSFGYSAITLWVAIQKANYFLIPISVTACLGFGMM
LVGFWQEERSIK
>Mature_492_residues
MLMLTVLSYAAQAVFFLVVVCFILYVLLELRVLGISRRVERHKLTELVSQLPGMLALPVWPRVSVLLPIYNEAAVIVRLI
DAVCRLQYPTSSLEILVLDDSTDNTSTLAQARIDYHADLGVSIRYVRRASNEGYKAGNLLNGIRQSSGEFYVIFDADFIP
QEDFLLRTVPYFQDPQLGFLQTGIGYENRDASFLTRFQAMEMGHQQYVTVGLSEDGDMASLSGSSCVWRRACVESLGGWN
ASTVTEDVDLGYRAQFGNWKYAYMRDVVSMSVLPETTSAFRVQRKRWGRGLIHSAFKHARQMFRQRMPLMQRLHAIAMMF
SSLLLASIYILLLLCLPLSYLVDFEGLGIHWVAWLFFGFVAIWGLNNVFAARKGAHIGEQRGILRTLWETYLYVAMFLPM
AWYYFAGGMRALFGVHGDFHRTLKGGSKKSVIRPPVHKILWMGDGFSFGYSAITLWVAIQKANYFLIPISVTACLGFGMM
LVGFWQEERSIK

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multic

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=393, Percent_Identity=30.2798982188295, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787259, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 55842; Mature: 55842

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLTVLSYAAQAVFFLVVVCFILYVLLELRVLGISRRVERHKLTELVSQLPGMLALPVW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
PRVSVLLPIYNEAAVIVRLIDAVCRLQYPTSSLEILVLDDSTDNTSTLAQARIDYHADLG
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCC
VSIRYVRRASNEGYKAGNLLNGIRQSSGEFYVIFDADFIPQEDFLLRTVPYFQDPQLGFL
CCHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCHH
QTGIGYENRDASFLTRFQAMEMGHQQYVTVGLSEDGDMASLSGSSCVWRRACVESLGGWN
HHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
ASTVTEDVDLGYRAQFGNWKYAYMRDVVSMSVLPETTSAFRVQRKRWGRGLIHSAFKHAR
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
QMFRQRMPLMQRLHAIAMMFSSLLLASIYILLLLCLPLSYLVDFEGLGIHWVAWLFFGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AIWGLNNVFAARKGAHIGEQRGILRTLWETYLYVAMFLPMAWYYFAGGMRALFGVHGDFH
HHHCCCHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHH
RTLKGGSKKSVIRPPVHKILWMGDGFSFGYSAITLWVAIQKANYFLIPISVTACLGFGMM
HHHCCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHEEECCCEEEEEHHHHHHHHHHHH
LVGFWQEERSIK
HHHHHHHHCCCC
>Mature Secondary Structure
MLMLTVLSYAAQAVFFLVVVCFILYVLLELRVLGISRRVERHKLTELVSQLPGMLALPVW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
PRVSVLLPIYNEAAVIVRLIDAVCRLQYPTSSLEILVLDDSTDNTSTLAQARIDYHADLG
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCC
VSIRYVRRASNEGYKAGNLLNGIRQSSGEFYVIFDADFIPQEDFLLRTVPYFQDPQLGFL
CCHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCHH
QTGIGYENRDASFLTRFQAMEMGHQQYVTVGLSEDGDMASLSGSSCVWRRACVESLGGWN
HHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
ASTVTEDVDLGYRAQFGNWKYAYMRDVVSMSVLPETTSAFRVQRKRWGRGLIHSAFKHAR
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
QMFRQRMPLMQRLHAIAMMFSSLLLASIYILLLLCLPLSYLVDFEGLGIHWVAWLFFGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AIWGLNNVFAARKGAHIGEQRGILRTLWETYLYVAMFLPMAWYYFAGGMRALFGVHGDFH
HHHCCCHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHH
RTLKGGSKKSVIRPPVHKILWMGDGFSFGYSAITLWVAIQKANYFLIPISVTACLGFGMM
HHHCCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHEEECCCEEEEEHHHHHHHHHHHH
LVGFWQEERSIK
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]