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The map label for this gene is katA [H]

Identifier: 114331941

GI number: 114331941

Start: 2083800

End: 2085257

Strand: Reverse

Name: katA [H]

Synonym: Neut_1969

Alternate gene names: 114331941

Gene position: 2085257-2083800 (Counterclockwise)

Preceding gene: 114331942

Following gene: 114331936

Centisome position: 78.36

GC content: 50.14

Gene sequence:

>1458_bases
ATGGATGATAGCAAAAGGAAATTGACGACCAGTGCCGGTGCACCGGTGCCGGATAATCAGAATGTCATGACTGCCGGGCC
GCGTGGCCCGATGTTACTGCAGGATGTCTGGTTTCTGGAAAAACTTGCGCATTTTGATCGTGAAGTGATTCCCGAGCGCC
GGATGCATGCCAAGGGCTCCGGTGCTTACGGCACCTTCACCGTGACACACGATATTACCCGTTACACGCAGGCAAAAATC
TTTTCGCAAATCGGTAAAAAAACTGAATTGTTCGTCCGCTTTTCCACGGTGGCGGGGGAGCGTGGCGCTGCTGATGCAGA
GCGGGATATTCGCGGCTTTGCCATCAAGTTCTATACTGAAGAAGGCAATTGGGATTTAGTGGGGAACAATACACCAGTAT
TTTTTCTGCGTGATCCGCTGAAGTTTCCGGATCTCAACCATGCCGTGAAACGGGATCCTCGTACTAATCTGCGCAGTGCA
CGCAATAACTGGGATTTTTGGACATTACTGCCGGAAGCTCTGCACCAGATTACCATTGTCATGAGCGATCGCGGTATTCC
TACAACGTATCGGCATATGCATGGTTTTGGCAGCCATACTTTCAGCTTCCTCAATGCCCAGCGAGAACGATACTGGGTGA
AGTTTCATTTCAGAACACAGCAGGGTATCAAGAATCTGACTGATGCCGAGGCGGAAACACTGATTGGCGAGGATCGGGAA
AGTCATCAGCGTGATCTGTACGAAAGCATTGAACGCGGCGAATTTCCACGCTGGACCTTATTTGTGCAAATCATGCCGGA
AAGTGATGTGGCCGATCTTTCTTATAACCCGTTTGATCTGACCAAAGTCTGGCCACACAAGGATTACCCATTGATTGAGG
TTGGTGTGATGGAGTTGAATCGTAATCCGGAAAATTATTTTGCCGAAGTTGAACAAGCGGCATTCAATCCGGCGAATGTC
ATACCAGGAATCAGTTTTTCACCAGACAAAATGTTGCAGGGACGACTGTTTTCCTATGGTGATGCGCAGCGCTATCGCTT
GGGTGTCAATCATCACCAGATTCCGGTCAATGCACCACGTTGCCCTTTTCATAACTACCATCGTGATGGCACTATGCGCG
TTGATGGTAATCACGACAGTACGCTGGGATATGAACCGAACAGTTATCAGGAGTGGCAGCAACAGCCCGGGTATGCAGAA
CCCCCTCTGGCACTAGAAGGCTCAGCCGCTCACTGGAATCATCGTGAGGATGGAGATTATTATACCCAGCCGGGTAATCT
GTTCCGGCTCATGAGCCCCGCGCAACAGCAGATACTGTTCGACAATACTGCGCGTGCTATCGGTGAAGCCTCCCGTGAAA
GCCAGCTCCGGCATATTATCCATTGTCTGAATGCAGATAGAGCTTATGCTGAAGGAGTTGCCAGGGCGTTGGAAATTCCA
ATGGGTGAAGTGGGGTAG

Upstream 100 bases:

>100_bases
TCCGGAGATTTCGCCGGATAGTGAGTAAATCTACCACAAGATCTGCTTCCAGTAGCAGAAAAAAAGGTGCCTGATGTAAA
ACTTACGGAAGGAGAGAAAA

Downstream 100 bases:

>100_bases
ATCTGAAATAGATTTACGATTGGCGCTGCGAGGATGCTCGTGCTGCTCAATATAAATGCCACAGCCAGAGCGCCAATGCC
AGTATCAGTCCGAGTAGGGC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MDDSKRKLTTSAGAPVPDNQNVMTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITRYTQAKI
FSQIGKKTELFVRFSTVAGERGAADAERDIRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSA
RNNWDFWTLLPEALHQITIVMSDRGIPTTYRHMHGFGSHTFSFLNAQRERYWVKFHFRTQQGIKNLTDAEAETLIGEDRE
SHQRDLYESIERGEFPRWTLFVQIMPESDVADLSYNPFDLTKVWPHKDYPLIEVGVMELNRNPENYFAEVEQAAFNPANV
IPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPFHNYHRDGTMRVDGNHDSTLGYEPNSYQEWQQQPGYAE
PPLALEGSAAHWNHREDGDYYTQPGNLFRLMSPAQQQILFDNTARAIGEASRESQLRHIIHCLNADRAYAEGVARALEIP
MGEVG

Sequences:

>Translated_485_residues
MDDSKRKLTTSAGAPVPDNQNVMTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITRYTQAKI
FSQIGKKTELFVRFSTVAGERGAADAERDIRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSA
RNNWDFWTLLPEALHQITIVMSDRGIPTTYRHMHGFGSHTFSFLNAQRERYWVKFHFRTQQGIKNLTDAEAETLIGEDRE
SHQRDLYESIERGEFPRWTLFVQIMPESDVADLSYNPFDLTKVWPHKDYPLIEVGVMELNRNPENYFAEVEQAAFNPANV
IPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPFHNYHRDGTMRVDGNHDSTLGYEPNSYQEWQQQPGYAE
PPLALEGSAAHWNHREDGDYYTQPGNLFRLMSPAQQQILFDNTARAIGEASRESQLRHIIHCLNADRAYAEGVARALEIP
MGEVG
>Mature_485_residues
MDDSKRKLTTSAGAPVPDNQNVMTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITRYTQAKI
FSQIGKKTELFVRFSTVAGERGAADAERDIRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSA
RNNWDFWTLLPEALHQITIVMSDRGIPTTYRHMHGFGSHTFSFLNAQRERYWVKFHFRTQQGIKNLTDAEAETLIGEDRE
SHQRDLYESIERGEFPRWTLFVQIMPESDVADLSYNPFDLTKVWPHKDYPLIEVGVMELNRNPENYFAEVEQAAFNPANV
IPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPFHNYHRDGTMRVDGNHDSTLGYEPNSYQEWQQQPGYAE
PPLALEGSAAHWNHREDGDYYTQPGNLFRLMSPAQQQILFDNTARAIGEASRESQLRHIIHCLNADRAYAEGVARALEIP
MGEVG

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=444, Percent_Identity=53.8288288288288, Blast_Score=496, Evalue=1e-140,
Organism=Escherichia coli, GI48994891, Length=488, Percent_Identity=43.4426229508197, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71998444, Length=445, Percent_Identity=51.9101123595506, Blast_Score=478, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI25147792, Length=450, Percent_Identity=50, Blast_Score=457, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI25151141, Length=450, Percent_Identity=50, Blast_Score=457, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6320462, Length=484, Percent_Identity=45.8677685950413, Blast_Score=403, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321525, Length=384, Percent_Identity=43.4895833333333, Blast_Score=317, Evalue=3e-87,
Organism=Drosophila melanogaster, GI17981717, Length=456, Percent_Identity=50.4385964912281, Blast_Score=465, Evalue=1e-131,
Organism=Drosophila melanogaster, GI19920968, Length=459, Percent_Identity=46.8409586056645, Blast_Score=445, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55643; Mature: 55643

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDSKRKLTTSAGAPVPDNQNVMTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS
CCCCCCEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAYGTFTVTHDITRYTQAKIFSQIGKKTELFVRFSTVAGERGAADAERDIRGFAIKFYTE
CCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCHHCCCEEEEEEEEE
EGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSARNNWDFWTLLPEALHQITIV
CCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHCEEEEE
MSDRGIPTTYRHMHGFGSHTFSFLNAQRERYWVKFHFRTQQGIKNLTDAEAETLIGEDRE
EECCCCCHHHHHHHCCCHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHHCCCHH
SHQRDLYESIERGEFPRWTLFVQIMPESDVADLSYNPFDLTKVWPHKDYPLIEVGVMELN
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEECEEECCCCCCCEEEEEEEEEC
RNPENYFAEVEQAAFNPANVIPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPR
CCHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCC
CPFHNYHRDGTMRVDGNHDSTLGYEPNSYQEWQQQPGYAEPPLALEGSAAHWNHREDGDY
CCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCE
YTQPGNLFRLMSPAQQQILFDNTARAIGEASRESQLRHIIHCLNADRAYAEGVARALEIP
EECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
MGEVG
CCCCC
>Mature Secondary Structure
MDDSKRKLTTSAGAPVPDNQNVMTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS
CCCCCCEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAYGTFTVTHDITRYTQAKIFSQIGKKTELFVRFSTVAGERGAADAERDIRGFAIKFYTE
CCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCHHCCCEEEEEEEEE
EGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSARNNWDFWTLLPEALHQITIV
CCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHCEEEEE
MSDRGIPTTYRHMHGFGSHTFSFLNAQRERYWVKFHFRTQQGIKNLTDAEAETLIGEDRE
EECCCCCHHHHHHHCCCHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHHCCCHH
SHQRDLYESIERGEFPRWTLFVQIMPESDVADLSYNPFDLTKVWPHKDYPLIEVGVMELN
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEECEEECCCCCCCEEEEEEEEEC
RNPENYFAEVEQAAFNPANVIPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPR
CCHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCC
CPFHNYHRDGTMRVDGNHDSTLGYEPNSYQEWQQQPGYAEPPLALEGSAAHWNHREDGDY
CCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCE
YTQPGNLFRLMSPAQQQILFDNTARAIGEASRESQLRHIIHCLNADRAYAEGVARALEIP
EECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
MGEVG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA