Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 114331914

GI number: 114331914

Start: 2052911

End: 2053717

Strand: Direct

Name: dapB

Synonym: Neut_1940

Alternate gene names: 114331914

Gene position: 2052911-2053717 (Clockwise)

Preceding gene: 114331913

Following gene: 114331916

Centisome position: 77.15

GC content: 50.06

Gene sequence:

>807_bases
ATGACGCTGTTAAATATAGCCGTTGCCGGAAGTACCGGCCGTATGGGTCGGACTATCATGGAAACTATTGCTGATGCGCA
AGATCTGCGGTTATCTGCAGCACTTGAACAACCCGACAGCCCATATCTGTCGCAAGATGCAGGCGGTTTAACCGGAACAC
CCTGCGGAGTTATCATCAACAGTGATTATGCCTCCGCACTGACAGGCAGCGATGTACTGATCGACTTTACTCGCCCCGCC
GGAACACTGACGCATCTTGCCGTATGTCGTCAATCAGGCATCCACATGGTGATCGGCACTACCGGATTTTCAGCAGAAGA
AAAAGAAATTATTCATGATGCAGCAAAAGACATCGCCATCGTGTTCGCTCCCAATATGAGCGTGGGTGTTAATATACTGT
TCAGGTTGCTTGAAGTCGCCGCAAAGGCGTTACCTGCTGGTTACGATGTGGAAATCATTGAGGCACATCACCGCCACAAA
GTGGACGCACCTTCTGGAACCGCTCTGCGTATGGGAGAAGTGATTGCCCAGACTCAGGGAAAAAATCTTGAGAAAGTAGC
AATTTATGGACGTGAAGGCCACACCGGGGAACGTGCGGCAGATACTATTGGATTTTCAACCATACGTGGTGGAGATATTG
TGGGCGACCACACGGCGTTATTTGCCGGAATCGGCGAGCGGCTGGAAATTACACATAAAGCCAGCAGCCGCAAAACATTT
GCAACAGGTGCATTGCATGCCGCGCGTTTTCTTGCTACTAAAAAATCCGGATTATTTGATATGCAGGATGTGCTGGGGCT
ACGCTGA

Upstream 100 bases:

>100_bases
CTGGATCCCCTCCTGGTGTTGATGGCACAGAAAACGAGGGATCTGACAAAACAATCGATTTCCTCAAAGAAAATCAGACA
AATTTTTACAGGGATAATCA

Downstream 100 bases:

>100_bases
TTTATACCAGCCTCATATATTGATAGTTTACGTCCAAGGAATCGCTAAGGAACCTCTGAAAAACGTTAACGAGATAGAAG
TTGGCAAAAAGGCAGCGTTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTLLNIAVAGSTGRMGRTIMETIADAQDLRLSAALEQPDSPYLSQDAGGLTGTPCGVIINSDYASALTGSDVLIDFTRPA
GTLTHLAVCRQSGIHMVIGTTGFSAEEKEIIHDAAKDIAIVFAPNMSVGVNILFRLLEVAAKALPAGYDVEIIEAHHRHK
VDAPSGTALRMGEVIAQTQGKNLEKVAIYGREGHTGERAADTIGFSTIRGGDIVGDHTALFAGIGERLEITHKASSRKTF
ATGALHAARFLATKKSGLFDMQDVLGLR

Sequences:

>Translated_268_residues
MTLLNIAVAGSTGRMGRTIMETIADAQDLRLSAALEQPDSPYLSQDAGGLTGTPCGVIINSDYASALTGSDVLIDFTRPA
GTLTHLAVCRQSGIHMVIGTTGFSAEEKEIIHDAAKDIAIVFAPNMSVGVNILFRLLEVAAKALPAGYDVEIIEAHHRHK
VDAPSGTALRMGEVIAQTQGKNLEKVAIYGREGHTGERAADTIGFSTIRGGDIVGDHTALFAGIGERLEITHKASSRKTF
ATGALHAARFLATKKSGLFDMQDVLGLR
>Mature_267_residues
TLLNIAVAGSTGRMGRTIMETIADAQDLRLSAALEQPDSPYLSQDAGGLTGTPCGVIINSDYASALTGSDVLIDFTRPAG
TLTHLAVCRQSGIHMVIGTTGFSAEEKEIIHDAAKDIAIVFAPNMSVGVNILFRLLEVAAKALPAGYDVEIIEAHHRHKV
DAPSGTALRMGEVIAQTQGKNLEKVAIYGREGHTGERAADTIGFSTIRGGDIVGDHTALFAGIGERLEITHKASSRKTFA
TGALHAARFLATKKSGLFDMQDVLGLR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=59.622641509434, Blast_Score=286, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_NITEC (Q0AER1)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748136.1
- ProteinModelPortal:   Q0AER1
- SMR:   Q0AER1
- STRING:   Q0AER1
- GeneID:   4273327
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1940
- NMPDR:   fig|335283.3.peg.1080
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q0AER1
- ProtClustDB:   PRK00048
- BioCyc:   NEUT335283:NEUT_1940-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28278; Mature: 28146

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLNIAVAGSTGRMGRTIMETIADAQDLRLSAALEQPDSPYLSQDAGGLTGTPCGVIIN
CEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
SDYASALTGSDVLIDFTRPAGTLTHLAVCRQSGIHMVIGTTGFSAEEKEIIHDAAKDIAI
CCHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCEEE
VFAPNMSVGVNILFRLLEVAAKALPAGYDVEIIEAHHRHKVDAPSGTALRMGEVIAQTQG
EEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHHHCC
KNLEKVAIYGREGHTGERAADTIGFSTIRGGDIVGDHTALFAGIGERLEITHKASSRKTF
CCCEEEEEECCCCCCCCHHHHHHCCEEECCCCEECCHHHHHHCCCCCEEEEECCCCCCCH
ATGALHAARFLATKKSGLFDMQDVLGLR
HHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure 
TLLNIAVAGSTGRMGRTIMETIADAQDLRLSAALEQPDSPYLSQDAGGLTGTPCGVIIN
EEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
SDYASALTGSDVLIDFTRPAGTLTHLAVCRQSGIHMVIGTTGFSAEEKEIIHDAAKDIAI
CCHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCEEE
VFAPNMSVGVNILFRLLEVAAKALPAGYDVEIIEAHHRHKVDAPSGTALRMGEVIAQTQG
EEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHHHCC
KNLEKVAIYGREGHTGERAADTIGFSTIRGGDIVGDHTALFAGIGERLEITHKASSRKTF
CCCEEEEEECCCCCCCCHHHHHHCCEEECCCCEECCHHHHHHCCCCCEEEEECCCCCCCH
ATGALHAARFLATKKSGLFDMQDVLGLR
HHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA