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The map label for this gene is fur [H]

Identifier: 114331912

GI number: 114331912

Start: 2051772

End: 2052221

Strand: Reverse

Name: fur [H]

Synonym: Neut_1938

Alternate gene names: 114331912

Gene position: 2052221-2051772 (Counterclockwise)

Preceding gene: 114331915

Following gene: 114331911

Centisome position: 77.12

GC content: 43.56

Gene sequence:

>450_bases
ATGAGTAAATCAGAAAATTTGAAAAGTATAGATCTTAAGACGATGGGATTGAAGACAACACTCCCGCGTTTGAAGATATT
AAATTTGTTTGAGAACAGCTCGATTCGGCATCTCTCGGCAGAAGACGTCTATAAAGAATTGCTAGGTGAGGGAGAGGATA
TCGGTCTGGCAACGGTTTATCGTGTTCTGACTCAGTTTGAGCAAGCCGGATTGCTTGAGCGTCACCATTTTGAAAGTGGT
AAGGCAGTTTTTGAGCTAGCCAGTGGTAATCATCATGACCACCTGGTATGCCTGCAATGTGGTCACGTTGAGGAATTCTT
CGATCCAGAAATCGAAAAGCGTCAGGTGAAAATTGCCAAGGAGCGGGGGTTTGTGTTGCAGGATCATTCTTTGTCATTGT
ATGCGGATTGCATAAAAAAAGACTGCCCAGACCGCATACGTAGTAAATAG

Upstream 100 bases:

>100_bases
CGCGTCAGGGAATTAGTCCTGACTAAAAAGAAATTATTATGAAGGTTTACGCTTTTCAATTGTCTCATAAATGCAGTAAT
TTCTTGAGGTAAATAACTTA

Downstream 100 bases:

>100_bases
ACAGCAACGCTGCTTGATGTATTCCTGAATCTGTAAACCAATGTAACGGGTAATCGCTCGCTGATCGTTGACATGCAACC
GACGACAAAAAACATTCGTA

Product: ferric uptake regulator, Fur family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSKSENLKSIDLKTMGLKTTLPRLKILNLFENSSIRHLSAEDVYKELLGEGEDIGLATVYRVLTQFEQAGLLERHHFESG
KAVFELASGNHHDHLVCLQCGHVEEFFDPEIEKRQVKIAKERGFVLQDHSLSLYADCIKKDCPDRIRSK

Sequences:

>Translated_149_residues
MSKSENLKSIDLKTMGLKTTLPRLKILNLFENSSIRHLSAEDVYKELLGEGEDIGLATVYRVLTQFEQAGLLERHHFESG
KAVFELASGNHHDHLVCLQCGHVEEFFDPEIEKRQVKIAKERGFVLQDHSLSLYADCIKKDCPDRIRSK
>Mature_148_residues
SKSENLKSIDLKTMGLKTTLPRLKILNLFENSSIRHLSAEDVYKELLGEGEDIGLATVYRVLTQFEQAGLLERHHFESGK
AVFELASGNHHDHLVCLQCGHVEEFFDPEIEKRQVKIAKERGFVLQDHSLSLYADCIKKDCPDRIRSK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=58.0152671755725, Blast_Score=156, Evalue=6e-40,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17023; Mature: 16892

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSENLKSIDLKTMGLKTTLPRLKILNLFENSSIRHLSAEDVYKELLGEGEDIGLATVY
CCCCCCCCCCCEECCCCHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
RVLTQFEQAGLLERHHFESGKAVFELASGNHHDHLVCLQCGHVEEFFDPEIEKRQVKIAK
HHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCHHHHCCCHHHHHHHHHH
ERGFVLQDHSLSLYADCIKKDCPDRIRSK
HCCEEEECCCHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
SKSENLKSIDLKTMGLKTTLPRLKILNLFENSSIRHLSAEDVYKELLGEGEDIGLATVY
CCCCCCCCCCEECCCCHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
RVLTQFEQAGLLERHHFESGKAVFELASGNHHDHLVCLQCGHVEEFFDPEIEKRQVKIAK
HHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCHHHHCCCHHHHHHHHHH
ERGFVLQDHSLSLYADCIKKDCPDRIRSK
HCCEEEECCCHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA