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The map label for this gene is nreB [H]

Identifier: 114331816

GI number: 114331816

Start: 1948671

End: 1950167

Strand: Reverse

Name: nreB [H]

Synonym: Neut_1840

Alternate gene names: 114331816

Gene position: 1950167-1948671 (Counterclockwise)

Preceding gene: 114331817

Following gene: 114331815

Centisome position: 73.29

GC content: 54.44

Gene sequence:

>1497_bases
ATGGTACGGACACTTGCAATTCTGATGGTTGAGCCTACGGCAGCGGAGGGTGAGCAGGTACGTGGTTTGCTGGAGCAGGG
CGGCCTGTCAGCCCAGGTGCATTGTGTGACGACAGATGCGCTGCCGGAGGTATTGCAGCAACAGGAGTGGGATCTGGTGC
TGGCGGGTGATCATCCGGATTTGGGCGTGGTGCCGGTACTGGATTCATTGACGGAACTAGGGCTGGATATTCCGGTAATT
GTGCTGGTTTCCCGGCAGGATGAGCAGGCCACAGCATGTTTATTTGCTGCGGGAGTACAGGATGTATTGCTGAAATCGGA
CTCGATACGGCTGATGGCAGCCATCCGGGGTTGCCAGCGGCATATTGAACATTTGCAAGATTTGTGCGAGGCGCAATCCG
CACTGGAAAGAAGCGAAGCCCGTTTTCGTGCGATTGCTTCCAATCTGCCGGGGCTGGTGTTCCAGTTTGTACTGGAATCG
GATGGCGGCGTTTTCTTTCCGTACGTCAGCGAGAGTTCCAGAACATTGCTCGGGCTTTCTCCCGATTACCTGCAGAAAAA
TCCGGATGCATTTGCTGGCTTGATTCTGACGGAAGATATGTCGGACTACGATCAATCGTTACAGAACTCGTGCAAACAGC
TTTCGGCGTGGAATTGGGAGGGACGTATTCAGGCGCGGGGAGATGCTGATGTGAAATGGATCAGCCTGCGAGCTACACCG
CGCCGGACGCCGCGTGGTGCCGTGTTGTGGGATGGAATTATGCTGAATATTACGCGTAATAAACAGATCGAACTGGAAAT
TGCCCGATCGCGTGCGCAATTGGAAGAGCTTTCGGCATATTCGCAAAAAGCAAAAGAGCAGGAGCGCACACGGATTGCCC
GCGAGATTCATGATGATATTGGTGGGACTCTGACGGCGATCAAGTGTGAATTGGTGCCTTGCCTGGATAACTCCAGCCGT
GCGCCGGAGTTTTATCGCAACAAGGCCGCAGCGGTGGAATCGCTGGTGGATATGGTGATTGACAGCACGCGCCGGATCGC
GCTCGATTTGCGACCAGGTGTGCTTGATTGCGGGATTGTAGCCGCGGTGCAATGGCAGGCCCGTGAATTTAATCAGCGTA
CCGGGATTGCTTGTGCTGTGGTGTGTGATGATGAGGAAATTTCACTGGATGGAGATCTGGCCGTGGCGATTTTTCGGGTT
TTTCAGGAAGCGCTGACCAACATCGCCAAGCATGCGGATGCATCGGAAGTGCGGGTGAAATTGTCCGAAGCGAGTGGCGA
AGTGTATCTGGAAGTGGCAGACAATGGCTGCGGCATTACGTACCCGGATATGGAGAAGGTAAATTCGTTCGGCATACGCA
GTATGCGCGAGCGCTGCCAACAGCTTGGCGGGCGGTTTCATATTCAGGGTGAACCCCAGACGGGTACGGGGGTGATGATC
TGGATTCCGGTGAATGGGCAGTCTTCATCGTCTTATCAGGATGAGTGGCCGGATTGA

Upstream 100 bases:

>100_bases
TTAATGTTAAAAGATTAACAGTAGCTACATCTGTATGTCATTGTGGCATTATCTGGTTGGTTGCCAGTTAGTTGGATGTG
TGGGGAGTTGAATAAGGTTG

Downstream 100 bases:

>100_bases
GGGATGAAACATGAGACAAGGAATGTCAGCTGATAGGGTGAGGATGTAATCATGATCAAGGTGATGATCACTGATGATCA
TGCAATTGTGCGCCAGGGGC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MVRTLAILMVEPTAAEGEQVRGLLEQGGLSAQVHCVTTDALPEVLQQQEWDLVLAGDHPDLGVVPVLDSLTELGLDIPVI
VLVSRQDEQATACLFAAGVQDVLLKSDSIRLMAAIRGCQRHIEHLQDLCEAQSALERSEARFRAIASNLPGLVFQFVLES
DGGVFFPYVSESSRTLLGLSPDYLQKNPDAFAGLILTEDMSDYDQSLQNSCKQLSAWNWEGRIQARGDADVKWISLRATP
RRTPRGAVLWDGIMLNITRNKQIELEIARSRAQLEELSAYSQKAKEQERTRIAREIHDDIGGTLTAIKCELVPCLDNSSR
APEFYRNKAAAVESLVDMVIDSTRRIALDLRPGVLDCGIVAAVQWQAREFNQRTGIACAVVCDDEEISLDGDLAVAIFRV
FQEALTNIAKHADASEVRVKLSEASGEVYLEVADNGCGITYPDMEKVNSFGIRSMRERCQQLGGRFHIQGEPQTGTGVMI
WIPVNGQSSSSYQDEWPD

Sequences:

>Translated_498_residues
MVRTLAILMVEPTAAEGEQVRGLLEQGGLSAQVHCVTTDALPEVLQQQEWDLVLAGDHPDLGVVPVLDSLTELGLDIPVI
VLVSRQDEQATACLFAAGVQDVLLKSDSIRLMAAIRGCQRHIEHLQDLCEAQSALERSEARFRAIASNLPGLVFQFVLES
DGGVFFPYVSESSRTLLGLSPDYLQKNPDAFAGLILTEDMSDYDQSLQNSCKQLSAWNWEGRIQARGDADVKWISLRATP
RRTPRGAVLWDGIMLNITRNKQIELEIARSRAQLEELSAYSQKAKEQERTRIAREIHDDIGGTLTAIKCELVPCLDNSSR
APEFYRNKAAAVESLVDMVIDSTRRIALDLRPGVLDCGIVAAVQWQAREFNQRTGIACAVVCDDEEISLDGDLAVAIFRV
FQEALTNIAKHADASEVRVKLSEASGEVYLEVADNGCGITYPDMEKVNSFGIRSMRERCQQLGGRFHIQGEPQTGTGVMI
WIPVNGQSSSSYQDEWPD
>Mature_498_residues
MVRTLAILMVEPTAAEGEQVRGLLEQGGLSAQVHCVTTDALPEVLQQQEWDLVLAGDHPDLGVVPVLDSLTELGLDIPVI
VLVSRQDEQATACLFAAGVQDVLLKSDSIRLMAAIRGCQRHIEHLQDLCEAQSALERSEARFRAIASNLPGLVFQFVLES
DGGVFFPYVSESSRTLLGLSPDYLQKNPDAFAGLILTEDMSDYDQSLQNSCKQLSAWNWEGRIQARGDADVKWISLRATP
RRTPRGAVLWDGIMLNITRNKQIELEIARSRAQLEELSAYSQKAKEQERTRIAREIHDDIGGTLTAIKCELVPCLDNSSR
APEFYRNKAAAVESLVDMVIDSTRRIALDLRPGVLDCGIVAAVQWQAREFNQRTGIACAVVCDDEEISLDGDLAVAIFRV
FQEALTNIAKHADASEVRVKLSEASGEVYLEVADNGCGITYPDMEKVNSFGIRSMRERCQQLGGRFHIQGEPQTGTGVMI
WIPVNGQSSSSYQDEWPD

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=199, Percent_Identity=28.643216080402, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082311, Length=215, Percent_Identity=34.8837209302326, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788812, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54943; Mature: 54943

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTLAILMVEPTAAEGEQVRGLLEQGGLSAQVHCVTTDALPEVLQQQEWDLVLAGDHPD
CCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCEEEECCCCC
LGVVPVLDSLTELGLDIPVIVLVSRQDEQATACLFAAGVQDVLLKSDSIRLMAAIRGCQR
CCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHH
HIEHLQDLCEAQSALERSEARFRAIASNLPGLVFQFVLESDGGVFFPYVSESSRTLLGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCEEEEEECCCCCEEECCC
PDYLQKNPDAFAGLILTEDMSDYDQSLQNSCKQLSAWNWEGRIQARGDADVKWISLRATP
HHHHHCCCCHHEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCC
RRTPRGAVLWDGIMLNITRNKQIELEIARSRAQLEELSAYSQKAKEQERTRIAREIHDDI
CCCCCCCEEECCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGTLTAIKCELVPCLDNSSRAPEFYRNKAAAVESLVDMVIDSTRRIALDLRPGVLDCGIV
CCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHH
AAVQWQAREFNQRTGIACAVVCDDEEISLDGDLAVAIFRVFQEALTNIAKHADASEVRVK
HHEEHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEE
LSEASGEVYLEVADNGCGITYPDMEKVNSFGIRSMRERCQQLGGRFHIQGEPQTGTGVMI
EECCCCEEEEEECCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCEEEEECCCCCCCEEEE
WIPVNGQSSSSYQDEWPD
EEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MVRTLAILMVEPTAAEGEQVRGLLEQGGLSAQVHCVTTDALPEVLQQQEWDLVLAGDHPD
CCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCEEEECCCCC
LGVVPVLDSLTELGLDIPVIVLVSRQDEQATACLFAAGVQDVLLKSDSIRLMAAIRGCQR
CCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHH
HIEHLQDLCEAQSALERSEARFRAIASNLPGLVFQFVLESDGGVFFPYVSESSRTLLGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCEEEEEECCCCCEEECCC
PDYLQKNPDAFAGLILTEDMSDYDQSLQNSCKQLSAWNWEGRIQARGDADVKWISLRATP
HHHHHCCCCHHEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCC
RRTPRGAVLWDGIMLNITRNKQIELEIARSRAQLEELSAYSQKAKEQERTRIAREIHDDI
CCCCCCCEEECCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGTLTAIKCELVPCLDNSSRAPEFYRNKAAAVESLVDMVIDSTRRIALDLRPGVLDCGIV
CCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHH
AAVQWQAREFNQRTGIACAVVCDDEEISLDGDLAVAIFRVFQEALTNIAKHADASEVRVK
HHEEHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEE
LSEASGEVYLEVADNGCGITYPDMEKVNSFGIRSMRERCQQLGGRFHIQGEPQTGTGVMI
EECCCCEEEEEECCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCEEEEECCCCCCCEEEE
WIPVNGQSSSSYQDEWPD
EEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA