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The map label for this gene is 114331786

Identifier: 114331786

GI number: 114331786

Start: 1921410

End: 1922330

Strand: Reverse

Name: 114331786

Synonym: Neut_1809

Alternate gene names: NA

Gene position: 1922330-1921410 (Counterclockwise)

Preceding gene: 114331787

Following gene: 114331784

Centisome position: 72.24

GC content: 46.8

Gene sequence:

>921_bases
ATGACTACTGCCTTTGTTACACATCCGATTTATCTGAAGCATGATATGAAACATGGCCATCCAGAATGTCCGGAACGATT
ACTGGCCATTCAGGAACAGCTTGTTGCCACCGATACGCTGCCACGTTTACAGCAATATGAAGCGCCACGTGCAACCGATG
ATCAGTTGATGCGAGCTCATACGGAAAGCTATGTGCATGAGATCAAATCAGCTGCACCACAGCAAGGCCTGGTTTGTCTT
GATAATGACACTGCGATGAATCCTTTTACCCTGGAAGCGGCTTATTATGCAGCCGGTGCAGTTGTTCTGGCGACGGATCT
GGTCATCGACAAGCAGGTGAAAAATGCATTCTGTGCCGTTCGTCCACCTGGACATCATGCAACGCGCAATCAGGCAATGG
GATTTTGTTTTTTTAACAATGTGGCGATTGGCGCAGCACATGCTTTGGCGCATCATGGTCTGCAACGTGTAGCAATTGTG
GATTTTGATGTGCATCACGGCAATGGTACTGAAGATATTTTTCAGGATGAGCCGCGTGTCTTGTTTTGCTCCACTTTTCA
GCACCCATTTTATCCGTATTGCGGCACTGATAGCGGGGGTGATCACATTATTAATGTACCGCTTGCTGCACATACGAATG
GACAAGCGTTCCGTGTAGCGGTAACGCATTATTGGCTGCCGGCACTGGAAGCATTCAAACCGGAAATTATCTTTATTTCG
GCTGGGTTTGATGCCCACCGGGAAGATACGCTGGCGCAATTAAATCTGGTTGAAGCAGATTATGTTTGGATTACCAGGCA
AATAATGGCTATTGCTGAAAAACATGCACAAAACCGAATTGTTTCAGTGCTGGAAGGCGGATATGCGTTGGGCGCATTGG
GAAGAAGTGTGACTACACATATCAGAACATTAGCAGAATAA

Upstream 100 bases:

>100_bases
CAGCAAATGGCTTTGACTATCTGCCACGGACCGCCCAGCTGCGAGACTGTAAAATCTGTTGTGTAAGTGCCCGAGCCTTC
ATCCCTTGTGAAGGTTTTCC

Downstream 100 bases:

>100_bases
TAGGCCAGTAATAGGGGGTAGGGGGCAGACCACGGGTTTTGCTAAGCTTGCCGTTTTTCGGGAAGTCTGTGTACCCTTCA
AAGAATTTCCCTGGTTCAAG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTTAFVTHPIYLKHDMKHGHPECPERLLAIQEQLVATDTLPRLQQYEAPRATDDQLMRAHTESYVHEIKSAAPQQGLVCL
DNDTAMNPFTLEAAYYAAGAVVLATDLVIDKQVKNAFCAVRPPGHHATRNQAMGFCFFNNVAIGAAHALAHHGLQRVAIV
DFDVHHGNGTEDIFQDEPRVLFCSTFQHPFYPYCGTDSGGDHIINVPLAAHTNGQAFRVAVTHYWLPALEAFKPEIIFIS
AGFDAHREDTLAQLNLVEADYVWITRQIMAIAEKHAQNRIVSVLEGGYALGALGRSVTTHIRTLAE

Sequences:

>Translated_306_residues
MTTAFVTHPIYLKHDMKHGHPECPERLLAIQEQLVATDTLPRLQQYEAPRATDDQLMRAHTESYVHEIKSAAPQQGLVCL
DNDTAMNPFTLEAAYYAAGAVVLATDLVIDKQVKNAFCAVRPPGHHATRNQAMGFCFFNNVAIGAAHALAHHGLQRVAIV
DFDVHHGNGTEDIFQDEPRVLFCSTFQHPFYPYCGTDSGGDHIINVPLAAHTNGQAFRVAVTHYWLPALEAFKPEIIFIS
AGFDAHREDTLAQLNLVEADYVWITRQIMAIAEKHAQNRIVSVLEGGYALGALGRSVTTHIRTLAE
>Mature_305_residues
TTAFVTHPIYLKHDMKHGHPECPERLLAIQEQLVATDTLPRLQQYEAPRATDDQLMRAHTESYVHEIKSAAPQQGLVCLD
NDTAMNPFTLEAAYYAAGAVVLATDLVIDKQVKNAFCAVRPPGHHATRNQAMGFCFFNNVAIGAAHALAHHGLQRVAIVD
FDVHHGNGTEDIFQDEPRVLFCSTFQHPFYPYCGTDSGGDHIINVPLAAHTNGQAFRVAVTHYWLPALEAFKPEIIFISA
GFDAHREDTLAQLNLVEADYVWITRQIMAIAEKHAQNRIVSVLEGGYALGALGRSVTTHIRTLAE

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=325, Percent_Identity=34.4615384615385, Blast_Score=165, Evalue=4e-41,
Organism=Homo sapiens, GI13128864, Length=301, Percent_Identity=33.2225913621262, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI226529806, Length=325, Percent_Identity=32.3076923076923, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI17158039, Length=338, Percent_Identity=30.7692307692308, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI30795202, Length=338, Percent_Identity=30.7692307692308, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI30795204, Length=338, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI148539870, Length=338, Percent_Identity=30.4733727810651, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI169234807, Length=338, Percent_Identity=30.4733727810651, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI153085395, Length=337, Percent_Identity=30.8605341246291, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI62750347, Length=341, Percent_Identity=29.6187683284457, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI62750349, Length=341, Percent_Identity=29.6187683284457, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI13128860, Length=257, Percent_Identity=24.124513618677, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI13128862, Length=262, Percent_Identity=25.9541984732824, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI293336691, Length=269, Percent_Identity=24.907063197026, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI8923769, Length=315, Percent_Identity=22.2222222222222, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=298, Percent_Identity=32.2147651006711, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206283, Length=299, Percent_Identity=32.1070234113712, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17540332, Length=299, Percent_Identity=32.1070234113712, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25154020, Length=297, Percent_Identity=34.006734006734, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25154022, Length=316, Percent_Identity=31.9620253164557, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17537347, Length=302, Percent_Identity=33.7748344370861, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193209491, Length=322, Percent_Identity=29.1925465838509, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17534739, Length=257, Percent_Identity=28.4046692607004, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508561, Length=269, Percent_Identity=24.907063197026, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=263, Percent_Identity=25.0950570342205, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324307, Length=316, Percent_Identity=29.4303797468354, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323999, Length=268, Percent_Identity=23.8805970149254, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321244, Length=257, Percent_Identity=27.2373540856031, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325141, Length=362, Percent_Identity=25.414364640884, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281360899, Length=303, Percent_Identity=33.993399339934, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24642144, Length=303, Percent_Identity=33.993399339934, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24642146, Length=303, Percent_Identity=33.993399339934, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24642142, Length=303, Percent_Identity=33.993399339934, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24641720, Length=348, Percent_Identity=32.7586206896552, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360799, Length=348, Percent_Identity=32.7586206896552, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360801, Length=348, Percent_Identity=32.7586206896552, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24657891, Length=256, Percent_Identity=26.5625, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644244, Length=320, Percent_Identity=24.6875, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33855; Mature: 33724

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAFVTHPIYLKHDMKHGHPECPERLLAIQEQLVATDTLPRLQQYEAPRATDDQLMRAH
CCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHH
TESYVHEIKSAAPQQGLVCLDNDTAMNPFTLEAAYYAAGAVVLATDLVIDKQVKNAFCAV
HHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHCHHEEHHHHHHHHHHHCCEEEE
RPPGHHATRNQAMGFCFFNNVAIGAAHALAHHGLQRVAIVDFDVHHGNGTEDIFQDEPRV
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHCCCCCE
LFCSTFQHPFYPYCGTDSGGDHIINVPLAAHTNGQAFRVAVTHYWLPALEAFKPEIIFIS
EEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHCCCCEEEEE
AGFDAHREDTLAQLNLVEADYVWITRQIMAIAEKHAQNRIVSVLEGGYALGALGRSVTTH
CCCCCCCHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRTLAE
HHHHCC
>Mature Secondary Structure 
TTAFVTHPIYLKHDMKHGHPECPERLLAIQEQLVATDTLPRLQQYEAPRATDDQLMRAH
CCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHH
TESYVHEIKSAAPQQGLVCLDNDTAMNPFTLEAAYYAAGAVVLATDLVIDKQVKNAFCAV
HHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHCHHEEHHHHHHHHHHHCCEEEE
RPPGHHATRNQAMGFCFFNNVAIGAAHALAHHGLQRVAIVDFDVHHGNGTEDIFQDEPRV
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHCCCCCE
LFCSTFQHPFYPYCGTDSGGDHIINVPLAAHTNGQAFRVAVTHYWLPALEAFKPEIIFIS
EEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHCCCCEEEEE
AGFDAHREDTLAQLNLVEADYVWITRQIMAIAEKHAQNRIVSVLEGGYALGALGRSVTTH
CCCCCCCHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRTLAE
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]