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The map label for this gene is pilQ [H]

Identifier: 114331780

GI number: 114331780

Start: 1913589

End: 1915751

Strand: Reverse

Name: pilQ [H]

Synonym: Neut_1803

Alternate gene names: 114331780

Gene position: 1915751-1913589 (Counterclockwise)

Preceding gene: 114331781

Following gene: 114331779

Centisome position: 71.99

GC content: 48.73

Gene sequence:

>2163_bases
ATGATAGATTGGAAAACGGGAAATCAATGGCGCAAGAGTTGCATAATCATGGCTGCTCATCGAGCTTGGCAATGTGTGTC
GGTGTGTGTTCTGCTGGTTGCGTGGACCGTTCAGGTTGTAGCTGCATCAACGTCAGTAAATACCCTTCGTGCACTGGATA
TTACGGCCCAAACAGATGGTCGTTTAATTGTTAAAGTGACATTGGATCGACCGATTGCGACGCTACCGGCCGGAGTATTG
CTGAATGATCCCGATCGTCTTTATTTTGATCTGGAGCAGGTCGCCAGCGCTCTGGGCGAGTCTGGCAAGATATCAGGTCG
TGGTGTAATAAAGAGTATGGATGTTGTGCCTGCCGAAGGCCGTACCCGTCTGGTTATGAATTTGTCAAAAGCAGTTAAGT
ATGAAATCAGCACGGAAGGTAACGATTTGCTGATAGCGCTCCGGGGCAATGAATTGGGGGAATCACTCAATCGTGCCGCC
GTTTCAGCTTCCATGCCAGCAAGAGGTGAAGCACAATTAAGCTTGCGGGATATCGATTTTCATCGTGGTACACAAGGTGA
GGGCAGGGTGGAGGTGGAGCTGTCACAACCAGGTGCGGTAGTCAATGTGCATAGTCAGGGAGGAAGGTTGCTTATCGAGT
TCATGAAGGCTTACCTCCCTCCCAATCTTGAGCGGCGGTTGAATGTGCTGGATTTTGCCACACCAGTACAGACAATTGAG
ACTATCGCGCGGGATGGTAACGTGCAGATGATTATCGAGCCGAAAGGGCGCTGGGAGCATACATCTTACCAAACCGGAAC
TAATTTTGCGGTAGAAGTCAGATCGGTAGTTGAAGGTGATGATATGCCCATTCACAAAAAGCTGATTGATGGAGGTTATA
CTGGTGAAAAACTTTCACTTAATTTTCAGGATGTTGAAATTCGCTCAATTCTTCAGGTTATCGCTGATTTTACTGATTTG
AATATCATTGCCAGCGACTCAGTTAAAGGTAATCTGACCCTGCGGCTGAAGGATGTTCCCTGGGATCAGGCGCTGGATAT
CGTGCTGCAAACGAGCGATCTTGATAAACGCAGGGTGGGTAATGTGATTTTTATCGCGCCACGGGAAGAAATGGCTGCTC
GTGAAAGATTACAGCTGGAGCAGAATCAGCAGATAACCGAGTTGGAAGTGTTGCAAACGGAAGCATTCAGACTGAATTAT
CGGACTGCCAGTTCGATTCCGCTTAAGGGTATTCTGAGTCAACGTGGTTCGGTGGAGGTTGATGACATCAGCAATACGCT
GACCGTTACCGATATTCCCACCAGGCTTGCAGAGGTGGCTCGGCATGTGGCCAATCTCGATACCCAGGTGCGCCAGGTCA
TGATTGAAACCCGTATTGTCGAGGCAACCGATACATTCAGCCGTAACCTGGGAGCTCGTTTTGGGGTGCAGAACGCAACT
CGGATCGGGAGTCAGACTAATGGACGGCGACTGGGTATTTCCGGGAATTTGGGTAATTCCAGTGAATTGGCTGCTGGTAC
GATATCACCTTCTGGTGGGGATAATCTTAACGTCAATTTACCGGCGGCTGCGCTTGCAGGAGTCGCGGGTGGCCCGGCTG
CACTCGGATTGAGCTTGATTAAGATTAACAACGGCACATTGATTAATCTGGAGCTTTCTGCGTTGGAATCGGATAGTCAG
GGCCGTATTATCGCTAGCCCGCGCCTGGTTACGGCTAATCGTGTGGAGGCGAGTATTGAGCAGGGTACGGAAATCCCTTT
TCAGACTATCAGTGTGACACGGCCACAGATTCAGTTTAAAAAAGCTGTTCTTGGCCTCAAGGTTACGCCACAAATCACTC
CTGATGATAATATCATCATGAAATTGCAGGTTAATCAGGATACTCGCGGAGAAAGCACACCGGCTGGCCCAGCCATTGAT
ACCAAGCAAATCGTCACCGAGGTGCTGGTAGAGAATGGGGGCACAGTTGTCATCGGCGGTATATTTGAACAGGTCGAAAA
GCGGGATCGTAACCAGATCCCGTTACTGGGAGATGTGCCGTTACTGGGAAATTTATTTAAAAATACCGCAAAGCGAGATG
ATAAACGAGAATTGCTGATATTCGTCACGCCGCGTATCCTGAACGAGAATTTGAGTAATAATATTCGATCCGCATTGAAT
TGA

Upstream 100 bases:

>100_bases
TTTCCGAGGAGGAAGTCAAATTGAGAGAGATTACGCGAGGTAGTGCGGATGAATGGGTTGAACGGGCCAGTGTACTCATG
CTGCAAACTCAGGAGCAAAA

Downstream 100 bases:

>100_bases
TATGAAAAACAATCAAAATAACAGTATCAAAAATTTTGTGTATTTGGCCCATGCTATAGCATTGACTTGATCAGGCTAAG
CGTTCATAATGCCCTGCTAT

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MIDWKTGNQWRKSCIIMAAHRAWQCVSVCVLLVAWTVQVVAASTSVNTLRALDITAQTDGRLIVKVTLDRPIATLPAGVL
LNDPDRLYFDLEQVASALGESGKISGRGVIKSMDVVPAEGRTRLVMNLSKAVKYEISTEGNDLLIALRGNELGESLNRAA
VSASMPARGEAQLSLRDIDFHRGTQGEGRVEVELSQPGAVVNVHSQGGRLLIEFMKAYLPPNLERRLNVLDFATPVQTIE
TIARDGNVQMIIEPKGRWEHTSYQTGTNFAVEVRSVVEGDDMPIHKKLIDGGYTGEKLSLNFQDVEIRSILQVIADFTDL
NIIASDSVKGNLTLRLKDVPWDQALDIVLQTSDLDKRRVGNVIFIAPREEMAARERLQLEQNQQITELEVLQTEAFRLNY
RTASSIPLKGILSQRGSVEVDDISNTLTVTDIPTRLAEVARHVANLDTQVRQVMIETRIVEATDTFSRNLGARFGVQNAT
RIGSQTNGRRLGISGNLGNSSELAAGTISPSGGDNLNVNLPAAALAGVAGGPAALGLSLIKINNGTLINLELSALESDSQ
GRIIASPRLVTANRVEASIEQGTEIPFQTISVTRPQIQFKKAVLGLKVTPQITPDDNIIMKLQVNQDTRGESTPAGPAID
TKQIVTEVLVENGGTVVIGGIFEQVEKRDRNQIPLLGDVPLLGNLFKNTAKRDDKRELLIFVTPRILNENLSNNIRSALN

Sequences:

>Translated_720_residues
MIDWKTGNQWRKSCIIMAAHRAWQCVSVCVLLVAWTVQVVAASTSVNTLRALDITAQTDGRLIVKVTLDRPIATLPAGVL
LNDPDRLYFDLEQVASALGESGKISGRGVIKSMDVVPAEGRTRLVMNLSKAVKYEISTEGNDLLIALRGNELGESLNRAA
VSASMPARGEAQLSLRDIDFHRGTQGEGRVEVELSQPGAVVNVHSQGGRLLIEFMKAYLPPNLERRLNVLDFATPVQTIE
TIARDGNVQMIIEPKGRWEHTSYQTGTNFAVEVRSVVEGDDMPIHKKLIDGGYTGEKLSLNFQDVEIRSILQVIADFTDL
NIIASDSVKGNLTLRLKDVPWDQALDIVLQTSDLDKRRVGNVIFIAPREEMAARERLQLEQNQQITELEVLQTEAFRLNY
RTASSIPLKGILSQRGSVEVDDISNTLTVTDIPTRLAEVARHVANLDTQVRQVMIETRIVEATDTFSRNLGARFGVQNAT
RIGSQTNGRRLGISGNLGNSSELAAGTISPSGGDNLNVNLPAAALAGVAGGPAALGLSLIKINNGTLINLELSALESDSQ
GRIIASPRLVTANRVEASIEQGTEIPFQTISVTRPQIQFKKAVLGLKVTPQITPDDNIIMKLQVNQDTRGESTPAGPAID
TKQIVTEVLVENGGTVVIGGIFEQVEKRDRNQIPLLGDVPLLGNLFKNTAKRDDKRELLIFVTPRILNENLSNNIRSALN
>Mature_720_residues
MIDWKTGNQWRKSCIIMAAHRAWQCVSVCVLLVAWTVQVVAASTSVNTLRALDITAQTDGRLIVKVTLDRPIATLPAGVL
LNDPDRLYFDLEQVASALGESGKISGRGVIKSMDVVPAEGRTRLVMNLSKAVKYEISTEGNDLLIALRGNELGESLNRAA
VSASMPARGEAQLSLRDIDFHRGTQGEGRVEVELSQPGAVVNVHSQGGRLLIEFMKAYLPPNLERRLNVLDFATPVQTIE
TIARDGNVQMIIEPKGRWEHTSYQTGTNFAVEVRSVVEGDDMPIHKKLIDGGYTGEKLSLNFQDVEIRSILQVIADFTDL
NIIASDSVKGNLTLRLKDVPWDQALDIVLQTSDLDKRRVGNVIFIAPREEMAARERLQLEQNQQITELEVLQTEAFRLNY
RTASSIPLKGILSQRGSVEVDDISNTLTVTDIPTRLAEVARHVANLDTQVRQVMIETRIVEATDTFSRNLGARFGVQNAT
RIGSQTNGRRLGISGNLGNSSELAAGTISPSGGDNLNVNLPAAALAGVAGGPAALGLSLIKINNGTLINLELSALESDSQ
GRIIASPRLVTANRVEASIEQGTEIPFQTISVTRPQIQFKKAVLGLKVTPQITPDDNIIMKLQVNQDTRGESTPAGPAID
TKQIVTEVLVENGGTVVIGGIFEQVEKRDRNQIPLLGDVPLLGNLFKNTAKRDDKRELLIFVTPRILNENLSNNIRSALN

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=424, Percent_Identity=33.4905660377358, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082242, Length=385, Percent_Identity=27.012987012987, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 78466; Mature: 78466

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDWKTGNQWRKSCIIMAAHRAWQCVSVCVLLVAWTVQVVAASTSVNTLRALDITAQTDG
CCCCCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCC
RLIVKVTLDRPIATLPAGVLLNDPDRLYFDLEQVASALGESGKISGRGVIKSMDVVPAEG
EEEEEEEECCCHHHCCCCEEECCCCCEEEEHHHHHHHCCCCCCCCCCCEEEECCEECCCC
RTRLVMNLSKAVKYEISTEGNDLLIALRGNELGESLNRAAVSASMPARGEAQLSLRDIDF
CEEEEEEECCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
HRGTQGEGRVEVELSQPGAVVNVHSQGGRLLIEFMKAYLPPNLERRLNVLDFATPVQTIE
CCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHCCHHHHCCHHHHHH
TIARDGNVQMIIEPKGRWEHTSYQTGTNFAVEVRSVVEGDDMPIHKKLIDGGYTGEKLSL
HHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCHHHHHHCCCCCCCEEEE
NFQDVEIRSILQVIADFTDLNIIASDSVKGNLTLRLKDVPWDQALDIVLQTSDLDKRRVG
EECCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHCC
NVIFIAPREEMAARERLQLEQNQQITELEVLQTEAFRLNYRTASSIPLKGILSQRGSVEV
CEEEEECCHHHHHHHHHHHHCCCCCHHHHHEEHEEEEEEECCCCCCCHHHHHCCCCCEEE
DDISNTLTVTDIPTRLAEVARHVANLDTQVRQVMIETRIVEATDTFSRNLGARFGVQNAT
ECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHCCCCCCCCCHHH
RIGSQTNGRRLGISGNLGNSSELAAGTISPSGGDNLNVNLPAAALAGVAGGPAALGLSLI
HCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCEEEEECCHHHHHCCCCCCHHHCEEEE
KINNGTLINLELSALESDSQGRIIASPRLVTANRVEASIEQGTEIPFQTISVTRPQIQFK
EECCCEEEEEEEEECCCCCCCCEEECCEEEECHHHHHHHHCCCCCCEEEEEECCCHHHEE
KAVLGLKVTPQITPDDNIIMKLQVNQDTRGESTPAGPAIDTKQIVTEVLVENGGTVVIGG
HHHCCEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECH
IFEQVEKRDRNQIPLLGDVPLLGNLFKNTAKRDDKRELLIFVTPRILNENLSNNIRSALN
HHHHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCCCEEEEEECCHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MIDWKTGNQWRKSCIIMAAHRAWQCVSVCVLLVAWTVQVVAASTSVNTLRALDITAQTDG
CCCCCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCC
RLIVKVTLDRPIATLPAGVLLNDPDRLYFDLEQVASALGESGKISGRGVIKSMDVVPAEG
EEEEEEEECCCHHHCCCCEEECCCCCEEEEHHHHHHHCCCCCCCCCCCEEEECCEECCCC
RTRLVMNLSKAVKYEISTEGNDLLIALRGNELGESLNRAAVSASMPARGEAQLSLRDIDF
CEEEEEEECCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
HRGTQGEGRVEVELSQPGAVVNVHSQGGRLLIEFMKAYLPPNLERRLNVLDFATPVQTIE
CCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHCCHHHHCCHHHHHH
TIARDGNVQMIIEPKGRWEHTSYQTGTNFAVEVRSVVEGDDMPIHKKLIDGGYTGEKLSL
HHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCHHHHHHCCCCCCCEEEE
NFQDVEIRSILQVIADFTDLNIIASDSVKGNLTLRLKDVPWDQALDIVLQTSDLDKRRVG
EECCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHCC
NVIFIAPREEMAARERLQLEQNQQITELEVLQTEAFRLNYRTASSIPLKGILSQRGSVEV
CEEEEECCHHHHHHHHHHHHCCCCCHHHHHEEHEEEEEEECCCCCCCHHHHHCCCCCEEE
DDISNTLTVTDIPTRLAEVARHVANLDTQVRQVMIETRIVEATDTFSRNLGARFGVQNAT
ECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHCCCCCCCCCHHH
RIGSQTNGRRLGISGNLGNSSELAAGTISPSGGDNLNVNLPAAALAGVAGGPAALGLSLI
HCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCEEEEECCHHHHHCCCCCCHHHCEEEE
KINNGTLINLELSALESDSQGRIIASPRLVTANRVEASIEQGTEIPFQTISVTRPQIQFK
EECCCEEEEEEEEECCCCCCCCEEECCEEEECHHHHHHHHCCCCCCEEEEEECCCHHHEE
KAVLGLKVTPQITPDDNIIMKLQVNQDTRGESTPAGPAIDTKQIVTEVLVENGGTVVIGG
HHHCCEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECH
IFEQVEKRDRNQIPLLGDVPLLGNLFKNTAKRDDKRELLIFVTPRILNENLSNNIRSALN
HHHHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCCCEEEEEECCHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]