Click here to switch to the map view.

The map label for this gene is silB [H]

Identifier: 114331743

GI number: 114331743

Start: 1872210

End: 1873373

Strand: Reverse

Name: silB [H]

Synonym: Neut_1766

Alternate gene names: 114331743

Gene position: 1873373-1872210 (Counterclockwise)

Preceding gene: 114331744

Following gene: 114331742

Centisome position: 70.4

GC content: 48.11

Gene sequence:

>1164_bases
ATGAGTTTCCAGATACAAACTATTGCAGTTATTTTTGCATTCGTAGTGCTTTCTATTTCGGGTTGCAGCAGCAAAGAAGA
GCAGGATTCCCCAGAAAAACATGTTAAAGCGGGATTGGCTGATTCCCATACAATTTTTCTCAGGCCGGATTTGCGTCAGC
GAGTTGAAACCGGTAAACCATTCCTTGCTGATATCTCCGAAAAGCTGCATGTTCCCGGTCAAATTAAGGTAAATGAGACG
AAACTTGTTCAGGTGGGAGCCAGTTTTACCGGAAGAATCGTCGAAGTTTATGCGCATTTAGGAGATAGTGTCGCAGCTGG
TGCCAAATTGGCCCGAATTACAAGTCCGGAATTAGTGCAGGCGCAATTAGCTTATCTTCGTGCTAATTCATTGGCCGTTC
TGGCAGAGCGTGCAGCCATACGTGCCAGACAGCTGTTCGCTGAGGATGTTATTAGTGCCGCCGAGCTGCAGCGCCGGGAA
TCGGAATCGCAGGTTTCGAACGCTGAACTGAGTGCAGCCAAGGATCAATTACTTTTACTGGGAGTAAATAATCAGGCAAT
ACAAGATCTGACCCGGCACGGGCAGATTCTTCCATCTGTTGTGATTACTGCCCCGCGCAGTGGCACAGTTATCGCGCGTA
ATGTAGCAGTTGGACAAGTAGTGCAGCCATCAGATCAATTGTTTACCGTAGCTGATTTATCTGAACTGTGGGTGGTAGGG
GATGTTCCGGAATACGCTGCGCATTTTGTTGAGCAGGGACAGCATGTGGAAGTTCGTGTGCCGGCACTGGGTGACGCAAA
TTTTGACGGGACTATCATTTTCGTATCCGATATTGTTAATCCGTTGACGAGGACAGTGACTGTCCGTACTGAGGTGGATA
ATCCTGAGCGTAAACTAAAGCCGGATATGCTGGCTACAGTGCATATTGATGAGCATGCGCGTGAACGTCTCGTTATCCCG
GAAGGCGCAGTGGTGCGTGAGCATAATGAAGATCACGTATTTGTCGCCCGGGAAGATGGTGGTTTCACATTAACCCAGGT
GAAGCTGGATGAACCAGTGAATCAGATGAGGCCTGTTCTGGAGGGATTAACACCAGATCAGCTGATTATTGTGAAGGGAG
CCTTCCATCTGAATAACGAGCGTAAACGCAAGGATCTGGAATAA

Upstream 100 bases:

>100_bases
TGCGCGCTCGGAATTATTGCAGGCCCAGTTCGAATTGCAGGCAGCAGCAGCAGAGATAGATCGGCTGCGGGCGCATTATC
CACAGGAGTAATTTTCCCCA

Downstream 100 bases:

>100_bases
CGATGATTATTTCTCTGGTACGCGCCATGCTGGCGCAGCGTTTGATAGTCGTCGTGGTTGCACTGATTCTGATGGGATTT
GGTCTGCATGCAGCACAGCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSFQIQTIAVIFAFVVLSISGCSSKEEQDSPEKHVKAGLADSHTIFLRPDLRQRVETGKPFLADISEKLHVPGQIKVNET
KLVQVGASFTGRIVEVYAHLGDSVAAGAKLARITSPELVQAQLAYLRANSLAVLAERAAIRARQLFAEDVISAAELQRRE
SESQVSNAELSAAKDQLLLLGVNNQAIQDLTRHGQILPSVVITAPRSGTVIARNVAVGQVVQPSDQLFTVADLSELWVVG
DVPEYAAHFVEQGQHVEVRVPALGDANFDGTIIFVSDIVNPLTRTVTVRTEVDNPERKLKPDMLATVHIDEHARERLVIP
EGAVVREHNEDHVFVAREDGGFTLTQVKLDEPVNQMRPVLEGLTPDQLIIVKGAFHLNNERKRKDLE

Sequences:

>Translated_387_residues
MSFQIQTIAVIFAFVVLSISGCSSKEEQDSPEKHVKAGLADSHTIFLRPDLRQRVETGKPFLADISEKLHVPGQIKVNET
KLVQVGASFTGRIVEVYAHLGDSVAAGAKLARITSPELVQAQLAYLRANSLAVLAERAAIRARQLFAEDVISAAELQRRE
SESQVSNAELSAAKDQLLLLGVNNQAIQDLTRHGQILPSVVITAPRSGTVIARNVAVGQVVQPSDQLFTVADLSELWVVG
DVPEYAAHFVEQGQHVEVRVPALGDANFDGTIIFVSDIVNPLTRTVTVRTEVDNPERKLKPDMLATVHIDEHARERLVIP
EGAVVREHNEDHVFVAREDGGFTLTQVKLDEPVNQMRPVLEGLTPDQLIIVKGAFHLNNERKRKDLE
>Mature_386_residues
SFQIQTIAVIFAFVVLSISGCSSKEEQDSPEKHVKAGLADSHTIFLRPDLRQRVETGKPFLADISEKLHVPGQIKVNETK
LVQVGASFTGRIVEVYAHLGDSVAAGAKLARITSPELVQAQLAYLRANSLAVLAERAAIRARQLFAEDVISAAELQRRES
ESQVSNAELSAAKDQLLLLGVNNQAIQDLTRHGQILPSVVITAPRSGTVIARNVAVGQVVQPSDQLFTVADLSELWVVGD
VPEYAAHFVEQGQHVEVRVPALGDANFDGTIIFVSDIVNPLTRTVTVRTEVDNPERKLKPDMLATVHIDEHARERLVIPE
GAVVREHNEDHVFVAREDGGFTLTQVKLDEPVNQMRPVLEGLTPDQLIIVKGAFHLNNERKRKDLE

Specific function: Component of the sil cation efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=310, Percent_Identity=23.8709677419355, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42467; Mature: 42336

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQIQTIAVIFAFVVLSISGCSSKEEQDSPEKHVKAGLADSHTIFLRPDLRQRVETGKP
CCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHCCCC
FLADISEKLHVPGQIKVNETKLVQVGASFTGRIVEVYAHLGDSVAAGAKLARITSPELVQ
HHHHHHHHCCCCCEEEECCEEEEEECCCCHHHHHHHHHHCCCCHHCCCCEEECCCHHHHH
AQLAYLRANSLAVLAERAAIRARQLFAEDVISAAELQRRESESQVSNAELSAAKDQLLLL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GVNNQAIQDLTRHGQILPSVVITAPRSGTVIARNVAVGQVVQPSDQLFTVADLSELWVVG
ECCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEECEECCEECCCCCEEEEECHHHEEEEC
DVPEYAAHFVEQGQHVEVRVPALGDANFDGTIIFVSDIVNPLTRTVTVRTEVDNPERKLK
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHEEEEEEECCCCHHHCC
PDMLATVHIDEHARERLVIPEGAVVREHNEDHVFVAREDGGFTLTQVKLDEPVNQMRPVL
CCEEEEEEECCCCCCEEECCCCCEEEECCCCEEEEEECCCCEEEEEEEECCCHHHHHHHH
EGLTPDQLIIVKGAFHLNNERKRKDLE
HCCCCCEEEEEEEEEECCCCHHHCCCC
>Mature Secondary Structure 
SFQIQTIAVIFAFVVLSISGCSSKEEQDSPEKHVKAGLADSHTIFLRPDLRQRVETGKP
CEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHCCCC
FLADISEKLHVPGQIKVNETKLVQVGASFTGRIVEVYAHLGDSVAAGAKLARITSPELVQ
HHHHHHHHCCCCCEEEECCEEEEEECCCCHHHHHHHHHHCCCCHHCCCCEEECCCHHHHH
AQLAYLRANSLAVLAERAAIRARQLFAEDVISAAELQRRESESQVSNAELSAAKDQLLLL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GVNNQAIQDLTRHGQILPSVVITAPRSGTVIARNVAVGQVVQPSDQLFTVADLSELWVVG
ECCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEECEECCEECCCCCEEEEECHHHEEEEC
DVPEYAAHFVEQGQHVEVRVPALGDANFDGTIIFVSDIVNPLTRTVTVRTEVDNPERKLK
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHEEEEEEECCCCHHHCC
PDMLATVHIDEHARERLVIPEGAVVREHNEDHVFVAREDGGFTLTQVKLDEPVNQMRPVL
CCEEEEEEECCCCCCEEECCCCCEEEECCCCEEEEEECCCCEEEEEEEECCCHHHHHHHH
EGLTPDQLIIVKGAFHLNNERKRKDLE
HCCCCCEEEEEEEEEECCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]