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The map label for this gene is lysA [H]

Identifier: 114331720

GI number: 114331720

Start: 1841609

End: 1842811

Strand: Reverse

Name: lysA [H]

Synonym: Neut_1742

Alternate gene names: 114331720

Gene position: 1842811-1841609 (Counterclockwise)

Preceding gene: 114331721

Following gene: 114331719

Centisome position: 69.25

GC content: 43.23

Gene sequence:

>1203_bases
ATGATGTTTGATGCTGAAAAATTCATATCGGTCATCCATGATTTGGCTCATCCGGATAAATCGTTATGCGCCTATTTGTA
TGATCTTGGGGCACTTGCATCTCATGCGAGAAATATCAAGAGTAGCTTACCGGACAGAGTGAATTTCTTTTATGCGATCA
AGGCTAATTCTGACCTGCCTATATTATCTGCGTTGGCAGAACATGTAGATGGTTTTGAAGCCTCTTCTGGGGGGGAGATT
CAATGGGTGCGGCAGAATTTTCCAGATGTGCCTTTGATATTCAGCGGGCCTGGGAAGCTAGATACAGAACTCGAATTGGC
CATCTTGAACAATGTGACTGTGCATATCGAGAGTCGGTTTGAATTAGAAAGATTGTTGCACATTGCAAGACACTATCAAC
AGCCAGCGGAAATCTTGTTGCGGGTGAATCCTCATTTTGAAGATTTACGAGCAACTTCTCTCATGATGGGGGGGAAACCG
ACTCAATTTGGCATCAGTGTGGAGCATTTGTCAGATTGCCTGAAAATGGTGAGGGATAACAGTGATTGTCTGTATTTCCA
GGGGTTCCATTTTCACTTACTTTCACATCAATTAGATGCCGCTCAACATTTACGCCTGTTATCTGCCTATATCGAACAGG
CAGTGAAATGGAAAGAGGAATTCAATCTTGTTATAGATCACATTAATGTAGGAGGTGGGATTGGTGTCAATTACAAAGAC
ATCGATCAGCAGTTTGACTGGTGTCATTTTTCGCATGGCTTGAACAATCTGCTGATTGGAGCCGCTAAAAACATTCCAAA
AATCCGGTTTGAGATGGGTCGGTATGTTTCTGCTTTCTGCGGCGTATATGTAGCAGAAGTGATCGACATCAAAACATCGG
GGAATGGAACATATGTCGTAGTGAAAGGAGGTACGCATCATTTTCGTACACCTTATGCCCAAAATCATAGCCATCCATTC
AAAGTTATTCCTGTCTCGACCTGGAAGAAACCATATTCCAGACCTGGTTTGAGGCATGGGAAGGTCAATATTGTGGGGCA
ATTGTGTACCCCTAAGGATTTATTGGCTTTTGATGAAATGGTGGGTGAAATTCGAGTGGGAGATATTGTTCTGTTTTCGC
ATGCAGGAGCATATGCCTGGCATATATCCCACCATGATTTTCTGCGTCATGCTCATCCCCAGCATATCTATTTGCCAGCT
TAG

Upstream 100 bases:

>100_bases
ATGCATTCCCGAGCAAGGCGAATCTGAGCAACCGATTCAGGATGCAGGCTGACAAATTGGCCGGATATATGCCTCTGATT
AACCCGATGGGGAGGTTGTC

Downstream 100 bases:

>100_bases
GCTGGCGTACCCCCCATTTATTTCATTATTTTTCAACACTATCAAAAATTATAATATGTCGAACAATAAAATGTATGGAG
TCAGCGTCATGGTCGGTGCC

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMFDAEKFISVIHDLAHPDKSLCAYLYDLGALASHARNIKSSLPDRVNFFYAIKANSDLPILSALAEHVDGFEASSGGEI
QWVRQNFPDVPLIFSGPGKLDTELELAILNNVTVHIESRFELERLLHIARHYQQPAEILLRVNPHFEDLRATSLMMGGKP
TQFGISVEHLSDCLKMVRDNSDCLYFQGFHFHLLSHQLDAAQHLRLLSAYIEQAVKWKEEFNLVIDHINVGGGIGVNYKD
IDQQFDWCHFSHGLNNLLIGAAKNIPKIRFEMGRYVSAFCGVYVAEVIDIKTSGNGTYVVVKGGTHHFRTPYAQNHSHPF
KVIPVSTWKKPYSRPGLRHGKVNIVGQLCTPKDLLAFDEMVGEIRVGDIVLFSHAGAYAWHISHHDFLRHAHPQHIYLPA

Sequences:

>Translated_400_residues
MMFDAEKFISVIHDLAHPDKSLCAYLYDLGALASHARNIKSSLPDRVNFFYAIKANSDLPILSALAEHVDGFEASSGGEI
QWVRQNFPDVPLIFSGPGKLDTELELAILNNVTVHIESRFELERLLHIARHYQQPAEILLRVNPHFEDLRATSLMMGGKP
TQFGISVEHLSDCLKMVRDNSDCLYFQGFHFHLLSHQLDAAQHLRLLSAYIEQAVKWKEEFNLVIDHINVGGGIGVNYKD
IDQQFDWCHFSHGLNNLLIGAAKNIPKIRFEMGRYVSAFCGVYVAEVIDIKTSGNGTYVVVKGGTHHFRTPYAQNHSHPF
KVIPVSTWKKPYSRPGLRHGKVNIVGQLCTPKDLLAFDEMVGEIRVGDIVLFSHAGAYAWHISHHDFLRHAHPQHIYLPA
>Mature_400_residues
MMFDAEKFISVIHDLAHPDKSLCAYLYDLGALASHARNIKSSLPDRVNFFYAIKANSDLPILSALAEHVDGFEASSGGEI
QWVRQNFPDVPLIFSGPGKLDTELELAILNNVTVHIESRFELERLLHIARHYQQPAEILLRVNPHFEDLRATSLMMGGKP
TQFGISVEHLSDCLKMVRDNSDCLYFQGFHFHLLSHQLDAAQHLRLLSAYIEQAVKWKEEFNLVIDHINVGGGIGVNYKD
IDQQFDWCHFSHGLNNLLIGAAKNIPKIRFEMGRYVSAFCGVYVAEVIDIKTSGNGTYVVVKGGTHHFRTPYAQNHSHPF
KVIPVSTWKKPYSRPGLRHGKVNIVGQLCTPKDLLAFDEMVGEIRVGDIVLFSHAGAYAWHISHHDFLRHAHPQHIYLPA

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=353, Percent_Identity=24.0793201133144, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 45170; Mature: 45170

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFDAEKFISVIHDLAHPDKSLCAYLYDLGALASHARNIKSSLPDRVNFFYAIKANSDLP
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
ILSALAEHVDGFEASSGGEIQWVRQNFPDVPLIFSGPGKLDTELELAILNNVTVHIESRF
HHHHHHHHHCCCCCCCCCCEEEHCCCCCCCCEEECCCCCCCCEEEEEEECCEEEEEECHH
ELERLLHIARHYQQPAEILLRVNPHFEDLRATSLMMGGKPTQFGISVEHLSDCLKMVRDN
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEECEEHHHHHHHHHHHHCC
SDCLYFQGFHFHLLSHQLDAAQHLRLLSAYIEQAVKWKEEFNLVIDHINVGGGIGVNYKD
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHH
IDQQFDWCHFSHGLNNLLIGAAKNIPKIRFEMGRYVSAFCGVYVAEVIDIKTSGNGTYVV
HHHCCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEE
VKGGTHHFRTPYAQNHSHPFKVIPVSTWKKPYSRPGLRHGKVNIVGQLCTPKDLLAFDEM
EECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
VGEIRVGDIVLFSHAGAYAWHISHHDFLRHAHPQHIYLPA
HCCEEECCEEEEECCCEEEEEECHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MMFDAEKFISVIHDLAHPDKSLCAYLYDLGALASHARNIKSSLPDRVNFFYAIKANSDLP
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
ILSALAEHVDGFEASSGGEIQWVRQNFPDVPLIFSGPGKLDTELELAILNNVTVHIESRF
HHHHHHHHHCCCCCCCCCCEEEHCCCCCCCCEEECCCCCCCCEEEEEEECCEEEEEECHH
ELERLLHIARHYQQPAEILLRVNPHFEDLRATSLMMGGKPTQFGISVEHLSDCLKMVRDN
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEECEEHHHHHHHHHHHHCC
SDCLYFQGFHFHLLSHQLDAAQHLRLLSAYIEQAVKWKEEFNLVIDHINVGGGIGVNYKD
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHH
IDQQFDWCHFSHGLNNLLIGAAKNIPKIRFEMGRYVSAFCGVYVAEVIDIKTSGNGTYVV
HHHCCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEE
VKGGTHHFRTPYAQNHSHPFKVIPVSTWKKPYSRPGLRHGKVNIVGQLCTPKDLLAFDEM
EECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
VGEIRVGDIVLFSHAGAYAWHISHHDFLRHAHPQHIYLPA
HCCEEECCEEEEECCCEEEEEECHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]