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The map label for this gene is merP

Identifier: 114331300

GI number: 114331300

Start: 1370490

End: 1370765

Strand: Direct

Name: merP

Synonym: Neut_1307

Alternate gene names: 114331300

Gene position: 1370490-1370765 (Clockwise)

Preceding gene: 114331299

Following gene: 114331301

Centisome position: 51.5

GC content: 60.51

Gene sequence:

>276_bases
ATGAAAAAACTGTTTGCCGCCCTCGCCCTCGCTGCCGTTGTTGCCCCCGTGTGGGCCGCCACCCAGACCGTCACGCTGTC
CGTACCGGGCATGACCTGCTCCACCTGCCCGATCACCGTCAAGAAGGCGATTTCCAAGGTCGAAGGCGTCAGCAAAATTG
ACGTGACCTTCGAGACACGCGAAGCGGTTGTCACGTTCGATGATGCCAAGACCAGCGTGCAGAAGCTGACCAAGGCAACC
GGAGACGCGGGCTATCCGTCCAGCGTCAAGCAGTGA

Upstream 100 bases:

>100_bases
TACTTACAAGCTCATTTTCTGGATCGTGGCCGCGCTGGTCCTGGTCGCGCTCGGATTTCCCTACGTCATGCCATTTTTCT
ATTAATCACAGGAGTTCATC

Downstream 100 bases:

>100_bases
GCCACTGAACCCGAACCTGGGGCGATCATGGGACTGATTACACGCATTGCCGACAAGGCTGGCGCGCTTGGCAGCGTTGT
TTCCGCGATGGGATGCGCTG

Product: mercuric transport protein periplasmic component

Products: NA

Alternate protein names: Mercury scavenger protein; Periplasmic mercury ion-binding protein

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCSTCPITVKKAISKVEGVSKIDVTFETREAVVTFDDAKTSVQKLTKAT
GDAGYPSSVKQ

Sequences:

>Translated_91_residues
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCSTCPITVKKAISKVEGVSKIDVTFETREAVVTFDDAKTSVQKLTKAT
GDAGYPSSVKQ
>Mature_91_residues
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCSTCPITVKKAISKVEGVSKIDVTFETREAVVTFDDAKTSVQKLTKAT
GDAGYPSSVKQ

Specific function: Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (merA) via the merT protein

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Periplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MERP_ALCSP (P94186)

Other databases:

- EMBL:   Y08993
- ProteinModelPortal:   P94186
- SMR:   P94186
- GO:   GO:0016020
- InterPro:   IPR001757
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR001802
- InterPro:   IPR011795
- PANTHER:   PTHR11939
- PRINTS:   PR00946
- TIGRFAMs:   TIGR02052

Pfam domain/function: PF00403 HMA; SSF55008 HeavyMe_transpt

EC number: NA

Molecular weight: Translated: 9505; Mature: 9505

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS01047 HMA_1; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCSTCPITVKKAISKVEGVSKIDVTFETR
CHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEECC
EAVVTFDDAKTSVQKLTKATGDAGYPSSVKQ
EEEEEECCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCSTCPITVKKAISKVEGVSKIDVTFETR
CHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEECC
EAVVTFDDAKTSVQKLTKATGDAGYPSSVKQ
EEEEEECCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9159519