Click here to switch to the map view.

The map label for this gene is glnE

Identifier: 114331261

GI number: 114331261

Start: 1326273

End: 1329062

Strand: Direct

Name: glnE

Synonym: Neut_1266

Alternate gene names: 114331261

Gene position: 1326273-1329062 (Clockwise)

Preceding gene: 114331252

Following gene: 114331262

Centisome position: 49.84

GC content: 46.99

Gene sequence:

>2790_bases
ATGACGACACCGATCAGCACATCCCGTGCAGCTTCCATTGTCAGCAGTATTCTGCCTTACAGTCGGTACTTGAAACGGGT
ACTGGAAAATGAATCCGAGCTTCAACAAGAACTTCTGGAGCAATTGCACAATCCCTTTACGCGGGAAGAAATGCTTGGTT
TTCTCCAGGACTCCACGGCGCACCTGATAGATGAGGCAGATTTACACCGTTTATTGCGTCAACTACGCAAGCGCGTCATT
CTCCGGCTGGCTGCACGCGATCTGGCCGGGCTGGCTGATCTGAACGAAGTCATGGCAACCATGACAGCTCTAGCCGATGT
AACGATCCAGTTTTCACTCGAATTTCTCCATGCAGCAATGGTGCAACCCGGGCACTTTGGTAAACCAAAAGGAGAAAAAA
CTGGTACAGAGCAACAATTGCTGATTGTAGCTATGGGAAAACTGGGCGGGGGCGAACTCAATGTATCCTCTGATGTAGAT
TTAGTTTTTATCTATCCCGAAGATGGCGAAACAGATGGCAGTAAATCCATTACCAATCATGAATTTTTTCTCAGACTCGG
GCGAAAGTTGATTGCCAGCCTCAATGATTATACCGTGGACGGTTATGTATTTCGTGTCGATATGCGATTGCGCCCGTACG
GCGAAAACAGCCCGCTCGCCATCAGCCTGCCCATGCTTGAAGACTATTTTGTTACACAAGGCCGCGAATGGGAGCGCCAC
GCCTGGATCAAAAGTCGCGTAATCACCGGCTCATCAATCGCTGAAGCAGCGTTGATGGAACTGATCGTACGTCCCTTTGT
ATTTCGCAAATATCTGGATTTTGAGGCCTATGAGGCGATGCGTAGTCTGCACACTCAACTGCGCAAAGAAGTAGATCGGC
GCGAGTTGCACGATAATATCAAGCTGGGCCCCGGTGGTATCCGTGAGATTGAATTTATCACCCAGGTGTTTCAGCTAATC
CGAGGAGGACGGGATGCCGATCTGTGTATTCGCCCTACTCTTGGCGTCTTGCAGCGATTAAAGCAGAAACAGCCTCTCCC
TGAACAGACAGTAGAAGAGCTGATTGAAGCCTATTACTTTCTGCGCAAACTTGAACACCGCCTGCAATATCTGGATGATC
AACAAACTCAGAATCTGCCACAACATTCAGATGATCAGATATTGATAGCAAAAAGTATGGGATTTACCGACTATACCGGT
TTTCTCAAACACCTTGATCTGCATCGCCAGAATGTTACCCGTCATTTTGAGCAAATTTTTGCAGTACGCCGCAAAGCCAT
AAAGCTTGGTACATTCGCCCGGATCAGGCCCGAACAAACCAACGACAACGAAATAGTTAAGGTCTTCAGTAATCAATTAA
AAACACTAGGATATATTGACCCTGACAAAATTACTGCACGTGTTCAGCAATTTTACGATGGCACTACGTTTCGGCAGCTA
AGCCACCCTAATCAGGAACGTATCCTGGAATTAATGCCCACATTAATGGAAGTGGTAACTCGATTTCCTCCTGTGGAAAT
TACGCTGGAACGTATGCTGCGATTACTCGAAAAAATCGGACAATATTCAGCCTACCTTGCTTTATTACAGGAGTATCCAC
AAACCCTGCCACGAGTAGCCAAATTGGTCAGTATCAGCCAATGGGCCAGTGATTATCTTGGCAGTCACCCGATTCTGCTG
GATGAATTACTTGCCCCATCCGGCCTGCACACCCTGCCAGACTGGCCAACGCTTAAAACAGAGCTTATCCATCAGCTGCA
TCACGGCAATATACCCAAGGCACAGATAATAGAATGGCAAATGGATGTACTACGACATTTTCAGCATGCGCAGGTGTTTC
GTTTGCTTGCTGTTGATCTTGAAGGAAATTTGTTGCTGGAAACACTCAGCGACCATTTAACCGCACTTGCTGATCTCATT
CTTGACAATGTTTTACAACTCGCCTGGCAGGGATTAAAAAAGAAACACCGGAAATCTCCTGCTTTTGCCATTATAGGCTA
CGGCAAACTGGGGGGAAAAGAATTGGGTTACGTATCCGATCTCGATATCGTCTATCTCTACCAGGACAATCACCCTGATG
CCATGGAGATTTATACTAAACTTGCCCAGAATATTAATCTATGGCTAACCAGCCATACCTCCGCCGGCGTACTTTACGAG
ACAGATCTAAGATTGCGCCCTAATGGCACCAGCGGATTGCTGGTCAATTCCATTGAGGCTTTTTCCCTGTATCAGCATGA
GCAGGCCTGGGTGTGGGAACATCAGGCATTGACACGTGCGCGCTTTGTCATTGGTGATAGTGAAGTGGGTGAAAAATTTG
AACAGATGCGTAAAAACATCCTTTGCCAACCGCGTGATATGGAAAATCTCAAACGGGAAATTCTGATGATGCGTACAAAA
ATGCTGGAAGCGCACCCAAATTCCACACCGTTATTCGATGTCAAGCATGATCACGGTGGCATTATTGACGTGGAATTTAT
TGTGCAATATCTGGTTCTGGGTTATGCCCACCGCTATCCACAATTAACCAGCAACATTGGTAACATTGCTTTACTCAAGC
TTGCCGGAGAACTTGGGCTGACATCCGCTGAGAAAGCAAATGCGGCGTTTATCGCCTATCGTGAACTTCGGCGTACACAA
CATCAACTCCGGCTGAGCGGCATACCTGAAGCCACCGGTACTGCTTTACCAAAAGATGTATCCCAGAAATTTGCTCGTGT
AACGAGCGATTACTTAAGCAGTGCCAGACGGGCAGTCTTTCAACTGTGGGAAGATGTTTTCGGAACGTAA

Upstream 100 bases:

>100_bases
AGTAAAAACAAAGCATTTTATGCGAAGCTATCGCCAAATCCGTAATACATCGAAGCAATAAAATCAGCAGCAATAACTTG
TCGCGTAACTACTATCTTAT

Downstream 100 bases:

>100_bases
GAAAATATTGAAATTGCGGGCAACAAAAGTAGGTTTTTTGGGGTGGCTGATGGGACTCGAACCCACGACAACCGGAATCA
CAATCCGGGACTCTACCAAC

Product: bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase

Products: NA

Alternate protein names: Glutamine-synthetase adenylyltransferase; ATase; [Glutamate--ammonia-ligase] adenylyltransferase

Number of amino acids: Translated: 929; Mature: 928

Protein sequence:

>929_residues
MTTPISTSRAASIVSSILPYSRYLKRVLENESELQQELLEQLHNPFTREEMLGFLQDSTAHLIDEADLHRLLRQLRKRVI
LRLAARDLAGLADLNEVMATMTALADVTIQFSLEFLHAAMVQPGHFGKPKGEKTGTEQQLLIVAMGKLGGGELNVSSDVD
LVFIYPEDGETDGSKSITNHEFFLRLGRKLIASLNDYTVDGYVFRVDMRLRPYGENSPLAISLPMLEDYFVTQGREWERH
AWIKSRVITGSSIAEAALMELIVRPFVFRKYLDFEAYEAMRSLHTQLRKEVDRRELHDNIKLGPGGIREIEFITQVFQLI
RGGRDADLCIRPTLGVLQRLKQKQPLPEQTVEELIEAYYFLRKLEHRLQYLDDQQTQNLPQHSDDQILIAKSMGFTDYTG
FLKHLDLHRQNVTRHFEQIFAVRRKAIKLGTFARIRPEQTNDNEIVKVFSNQLKTLGYIDPDKITARVQQFYDGTTFRQL
SHPNQERILELMPTLMEVVTRFPPVEITLERMLRLLEKIGQYSAYLALLQEYPQTLPRVAKLVSISQWASDYLGSHPILL
DELLAPSGLHTLPDWPTLKTELIHQLHHGNIPKAQIIEWQMDVLRHFQHAQVFRLLAVDLEGNLLLETLSDHLTALADLI
LDNVLQLAWQGLKKKHRKSPAFAIIGYGKLGGKELGYVSDLDIVYLYQDNHPDAMEIYTKLAQNINLWLTSHTSAGVLYE
TDLRLRPNGTSGLLVNSIEAFSLYQHEQAWVWEHQALTRARFVIGDSEVGEKFEQMRKNILCQPRDMENLKREILMMRTK
MLEAHPNSTPLFDVKHDHGGIIDVEFIVQYLVLGYAHRYPQLTSNIGNIALLKLAGELGLTSAEKANAAFIAYRELRRTQ
HQLRLSGIPEATGTALPKDVSQKFARVTSDYLSSARRAVFQLWEDVFGT

Sequences:

>Translated_929_residues
MTTPISTSRAASIVSSILPYSRYLKRVLENESELQQELLEQLHNPFTREEMLGFLQDSTAHLIDEADLHRLLRQLRKRVI
LRLAARDLAGLADLNEVMATMTALADVTIQFSLEFLHAAMVQPGHFGKPKGEKTGTEQQLLIVAMGKLGGGELNVSSDVD
LVFIYPEDGETDGSKSITNHEFFLRLGRKLIASLNDYTVDGYVFRVDMRLRPYGENSPLAISLPMLEDYFVTQGREWERH
AWIKSRVITGSSIAEAALMELIVRPFVFRKYLDFEAYEAMRSLHTQLRKEVDRRELHDNIKLGPGGIREIEFITQVFQLI
RGGRDADLCIRPTLGVLQRLKQKQPLPEQTVEELIEAYYFLRKLEHRLQYLDDQQTQNLPQHSDDQILIAKSMGFTDYTG
FLKHLDLHRQNVTRHFEQIFAVRRKAIKLGTFARIRPEQTNDNEIVKVFSNQLKTLGYIDPDKITARVQQFYDGTTFRQL
SHPNQERILELMPTLMEVVTRFPPVEITLERMLRLLEKIGQYSAYLALLQEYPQTLPRVAKLVSISQWASDYLGSHPILL
DELLAPSGLHTLPDWPTLKTELIHQLHHGNIPKAQIIEWQMDVLRHFQHAQVFRLLAVDLEGNLLLETLSDHLTALADLI
LDNVLQLAWQGLKKKHRKSPAFAIIGYGKLGGKELGYVSDLDIVYLYQDNHPDAMEIYTKLAQNINLWLTSHTSAGVLYE
TDLRLRPNGTSGLLVNSIEAFSLYQHEQAWVWEHQALTRARFVIGDSEVGEKFEQMRKNILCQPRDMENLKREILMMRTK
MLEAHPNSTPLFDVKHDHGGIIDVEFIVQYLVLGYAHRYPQLTSNIGNIALLKLAGELGLTSAEKANAAFIAYRELRRTQ
HQLRLSGIPEATGTALPKDVSQKFARVTSDYLSSARRAVFQLWEDVFGT
>Mature_928_residues
TTPISTSRAASIVSSILPYSRYLKRVLENESELQQELLEQLHNPFTREEMLGFLQDSTAHLIDEADLHRLLRQLRKRVIL
RLAARDLAGLADLNEVMATMTALADVTIQFSLEFLHAAMVQPGHFGKPKGEKTGTEQQLLIVAMGKLGGGELNVSSDVDL
VFIYPEDGETDGSKSITNHEFFLRLGRKLIASLNDYTVDGYVFRVDMRLRPYGENSPLAISLPMLEDYFVTQGREWERHA
WIKSRVITGSSIAEAALMELIVRPFVFRKYLDFEAYEAMRSLHTQLRKEVDRRELHDNIKLGPGGIREIEFITQVFQLIR
GGRDADLCIRPTLGVLQRLKQKQPLPEQTVEELIEAYYFLRKLEHRLQYLDDQQTQNLPQHSDDQILIAKSMGFTDYTGF
LKHLDLHRQNVTRHFEQIFAVRRKAIKLGTFARIRPEQTNDNEIVKVFSNQLKTLGYIDPDKITARVQQFYDGTTFRQLS
HPNQERILELMPTLMEVVTRFPPVEITLERMLRLLEKIGQYSAYLALLQEYPQTLPRVAKLVSISQWASDYLGSHPILLD
ELLAPSGLHTLPDWPTLKTELIHQLHHGNIPKAQIIEWQMDVLRHFQHAQVFRLLAVDLEGNLLLETLSDHLTALADLIL
DNVLQLAWQGLKKKHRKSPAFAIIGYGKLGGKELGYVSDLDIVYLYQDNHPDAMEIYTKLAQNINLWLTSHTSAGVLYET
DLRLRPNGTSGLLVNSIEAFSLYQHEQAWVWEHQALTRARFVIGDSEVGEKFEQMRKNILCQPRDMENLKREILMMRTKM
LEAHPNSTPLFDVKHDHGGIIDVEFIVQYLVLGYAHRYPQLTSNIGNIALLKLAGELGLTSAEKANAAFIAYRELRRTQH
QLRLSGIPEATGTALPKDVSQKFARVTSDYLSSARRAVFQLWEDVFGT

Specific function: Adenylation and deadenylation of glutamate--ammonia ligase

COG id: COG1391

COG function: function code OT; Glutamine synthetase adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glnE family

Homologues:

Organism=Escherichia coli, GI1789433, Length=944, Percent_Identity=37.1822033898305, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLNE_NITEC (Q0AGL4)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747483.1
- ProteinModelPortal:   Q0AGL4
- SMR:   Q0AGL4
- STRING:   Q0AGL4
- GeneID:   4273937
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1266
- NMPDR:   fig|335283.3.peg.2176
- eggNOG:   COG1391
- HOGENOM:   HBG687047
- OMA:   VLGMGKL
- PhylomeDB:   Q0AGL4
- ProtClustDB:   PRK11072
- BioCyc:   NEUT335283:NEUT_1266-MONOMER
- HAMAP:   MF_00802
- InterPro:   IPR023057
- InterPro:   IPR005190
- InterPro:   IPR013546

Pfam domain/function: PF08335 GlnD_UR_UTase; PF03710 GlnE

EC number: =2.7.7.42

Molecular weight: Translated: 106391; Mature: 106260

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPISTSRAASIVSSILPYSRYLKRVLENESELQQELLEQLHNPFTREEMLGFLQDSTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
HLIDEADLHRLLRQLRKRVILRLAARDLAGLADLNEVMATMTALADVTIQFSLEFLHAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQPGHFGKPKGEKTGTEQQLLIVAMGKLGGGELNVSSDVDLVFIYPEDGETDGSKSITNH
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCHH
EFFLRLGRKLIASLNDYTVDGYVFRVDMRLRPYGENSPLAISLPMLEDYFVTQGREWERH
HHHHHHHHHHHHHCCCCEECCEEEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCCHHHH
AWIKSRVITGSSIAEAALMELIVRPFVFRKYLDFEAYEAMRSLHTQLRKEVDRRELHDNI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KLGPGGIREIEFITQVFQLIRGGRDADLCIRPTLGVLQRLKQKQPLPEQTVEELIEAYYF
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LRKLEHRLQYLDDQQTQNLPQHSDDQILIAKSMGFTDYTGFLKHLDLHRQNVTRHFEQIF
HHHHHHHHHHHCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVRRKAIKLGTFARIRPEQTNDNEIVKVFSNQLKTLGYIDPDKITARVQQFYDGTTFRQL
HHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
SHPNQERILELMPTLMEVVTRFPPVEITLERMLRLLEKIGQYSAYLALLQEYPQTLPRVA
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLVSISQWASDYLGSHPILLDELLAPSGLHTLPDWPTLKTELIHQLHHGNIPKAQIIEWQ
HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
MDVLRHFQHAQVFRLLAVDLEGNLLLETLSDHLTALADLILDNVLQLAWQGLKKKHRKSP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AFAIIGYGKLGGKELGYVSDLDIVYLYQDNHPDAMEIYTKLAQNINLWLTSHTSAGVLYE
CEEEEEECCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCEEEE
TDLRLRPNGTSGLLVNSIEAFSLYQHEQAWVWEHQALTRARFVIGDSEVGEKFEQMRKNI
ECEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCC
LCQPRDMENLKREILMMRTKMLEAHPNSTPLFDVKHDHGGIIDVEFIVQYLVLGYAHRYP
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCC
QLTSNIGNIALLKLAGELGLTSAEKANAAFIAYRELRRTQHQLRLSGIPEATGTALPKDV
HHHCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
SQKFARVTSDYLSSARRAVFQLWEDVFGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPISTSRAASIVSSILPYSRYLKRVLENESELQQELLEQLHNPFTREEMLGFLQDSTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHH
HLIDEADLHRLLRQLRKRVILRLAARDLAGLADLNEVMATMTALADVTIQFSLEFLHAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQPGHFGKPKGEKTGTEQQLLIVAMGKLGGGELNVSSDVDLVFIYPEDGETDGSKSITNH
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCHH
EFFLRLGRKLIASLNDYTVDGYVFRVDMRLRPYGENSPLAISLPMLEDYFVTQGREWERH
HHHHHHHHHHHHHCCCCEECCEEEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCCHHHH
AWIKSRVITGSSIAEAALMELIVRPFVFRKYLDFEAYEAMRSLHTQLRKEVDRRELHDNI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KLGPGGIREIEFITQVFQLIRGGRDADLCIRPTLGVLQRLKQKQPLPEQTVEELIEAYYF
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LRKLEHRLQYLDDQQTQNLPQHSDDQILIAKSMGFTDYTGFLKHLDLHRQNVTRHFEQIF
HHHHHHHHHHHCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVRRKAIKLGTFARIRPEQTNDNEIVKVFSNQLKTLGYIDPDKITARVQQFYDGTTFRQL
HHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
SHPNQERILELMPTLMEVVTRFPPVEITLERMLRLLEKIGQYSAYLALLQEYPQTLPRVA
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLVSISQWASDYLGSHPILLDELLAPSGLHTLPDWPTLKTELIHQLHHGNIPKAQIIEWQ
HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
MDVLRHFQHAQVFRLLAVDLEGNLLLETLSDHLTALADLILDNVLQLAWQGLKKKHRKSP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AFAIIGYGKLGGKELGYVSDLDIVYLYQDNHPDAMEIYTKLAQNINLWLTSHTSAGVLYE
CEEEEEECCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCEEEE
TDLRLRPNGTSGLLVNSIEAFSLYQHEQAWVWEHQALTRARFVIGDSEVGEKFEQMRKNI
ECEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCC
LCQPRDMENLKREILMMRTKMLEAHPNSTPLFDVKHDHGGIIDVEFIVQYLVLGYAHRYP
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCC
QLTSNIGNIALLKLAGELGLTSAEKANAAFIAYRELRRTQHQLRLSGIPEATGTALPKDV
HHHCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
SQKFARVTSDYLSSARRAVFQLWEDVFGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA