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The map label for this gene is cysH1 [H]

Identifier: 114331185

GI number: 114331185

Start: 1240172

End: 1240870

Strand: Direct

Name: cysH1 [H]

Synonym: Neut_1187

Alternate gene names: 114331185

Gene position: 1240172-1240870 (Clockwise)

Preceding gene: 114331181

Following gene: 114331186

Centisome position: 46.6

GC content: 43.49

Gene sequence:

>699_bases
ATGGATGAGCAAACATTGCAACAGAAGGTTGAGCAGTTACACAGTTTGTTAGGTAATATCCAGCGGGATTATTCTCCCGC
TGTATTTGCCAACAGTTTTGGTGCTGAAGATATGGTATTGACTGATGTAATCGCTCGCCATCATCCGGAAATTGGCATAT
TTACGCTTGATACCGGACGTCTTCCACAGGAAACTTATGATCTGATACAAAAGACGAAGGAGCGTTATGGTGTTTCCGTC
CATGCTTATTTTCCTGATTCATCGTCTGTTGAGAACTATGTGACGCAATATGGCCCAAATGGGTTTTATGAAAGTATTGA
TCTGCGAAAACGTTGTTGCTATATACGAAAAGTTGAACCGCTAAAGCGTGCTTTGGCTGGAAAGCGTGCCTGGATTACAG
GAATGCGTCGCGAGCAATCAACCACCCGGGAGGAGCTGAAGTTATCAGTATTTGATAACATTCACGGTATACATAAATTT
AATCCCTTGTGCGACTGGACTGAGAAGGATGTATGGAACTATATAAAGCAGCACAATATTCCCTACAATGCGTTGCATGA
CCAATTTTATCCCAGCATCGGCTGTGCTCCATGTACTCGGGCAATAACTCCCGGGGAAGATATTCGATCCGGGCGTTGGT
GGTGGGAAAACCCAGACTCTAAAGAATGTGGTTTACATACTACAAAAGCAGAAACATAA

Upstream 100 bases:

>100_bases
TATGACAAGTAGCGTAGCGTAAGGATTCACATCGGGTTGGCGTGCTTATATAGATTTTTTATGGATATGTATTTGTCAGG
TAAAATAACGCTTTATTAAT

Downstream 100 bases:

>100_bases
GTTAATGTTCTTAAATCAAAATAAAATGAATCAACAGTCATATTTTACACATTTGGATGCCTTGGAAAACGAGGCTATCC
ATATCATGCGAGAAGTTGCG

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MDEQTLQQKVEQLHSLLGNIQRDYSPAVFANSFGAEDMVLTDVIARHHPEIGIFTLDTGRLPQETYDLIQKTKERYGVSV
HAYFPDSSSVENYVTQYGPNGFYESIDLRKRCCYIRKVEPLKRALAGKRAWITGMRREQSTTREELKLSVFDNIHGIHKF
NPLCDWTEKDVWNYIKQHNIPYNALHDQFYPSIGCAPCTRAITPGEDIRSGRWWWENPDSKECGLHTTKAET

Sequences:

>Translated_232_residues
MDEQTLQQKVEQLHSLLGNIQRDYSPAVFANSFGAEDMVLTDVIARHHPEIGIFTLDTGRLPQETYDLIQKTKERYGVSV
HAYFPDSSSVENYVTQYGPNGFYESIDLRKRCCYIRKVEPLKRALAGKRAWITGMRREQSTTREELKLSVFDNIHGIHKF
NPLCDWTEKDVWNYIKQHNIPYNALHDQFYPSIGCAPCTRAITPGEDIRSGRWWWENPDSKECGLHTTKAET
>Mature_232_residues
MDEQTLQQKVEQLHSLLGNIQRDYSPAVFANSFGAEDMVLTDVIARHHPEIGIFTLDTGRLPQETYDLIQKTKERYGVSV
HAYFPDSSSVENYVTQYGPNGFYESIDLRKRCCYIRKVEPLKRALAGKRAWITGMRREQSTTREELKLSVFDNIHGIHKF
NPLCDWTEKDVWNYIKQHNIPYNALHDQFYPSIGCAPCTRAITPGEDIRSGRWWWENPDSKECGLHTTKAET

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=212, Percent_Identity=29.2452830188679, Blast_Score=92, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325425, Length=214, Percent_Identity=33.1775700934579, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26885; Mature: 26885

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQTLQQKVEQLHSLLGNIQRDYSPAVFANSFGAEDMVLTDVIARHHPEIGIFTLDTGR
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCC
LPQETYDLIQKTKERYGVSVHAYFPDSSSVENYVTQYGPNGFYESIDLRKRCCYIRKVEP
CCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKRALAGKRAWITGMRREQSTTREELKLSVFDNIHGIHKFNPLCDWTEKDVWNYIKQHNI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHCCC
PYNALHDQFYPSIGCAPCTRAITPGEDIRSGRWWWENPDSKECGLHTTKAET
CHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEQTLQQKVEQLHSLLGNIQRDYSPAVFANSFGAEDMVLTDVIARHHPEIGIFTLDTGR
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCC
LPQETYDLIQKTKERYGVSVHAYFPDSSSVENYVTQYGPNGFYESIDLRKRCCYIRKVEP
CCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKRALAGKRAWITGMRREQSTTREELKLSVFDNIHGIHKFNPLCDWTEKDVWNYIKQHNI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHCCC
PYNALHDQFYPSIGCAPCTRAITPGEDIRSGRWWWENPDSKECGLHTTKAET
CHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]