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The map label for this gene is fbp

Identifier: 114331174

GI number: 114331174

Start: 1227503

End: 1228507

Strand: Direct

Name: fbp

Synonym: Neut_1176

Alternate gene names: 114331174

Gene position: 1227503-1228507 (Clockwise)

Preceding gene: 114331172

Following gene: 114331181

Centisome position: 46.13

GC content: 50.85

Gene sequence:

>1005_bases
ATGCATACCGGTACTACCCTTACCCAATTTATCATTGAAGATCAGCGCCACATTGCGGGTGCAAGCGGTGATTTCACCGC
GCTACTGAACGATATCGTGACCGCCATCAAGACCATTTCCAACGCGGTAAACAAAGGTGCACTGATTGGTGTCATGGGGG
CGCTGGATACGGAAAATGTCCAGGGTGAAACACAAAAGAAGCTGGATGTGATCACCAACGAAATTATGATTCGCCATAAT
GAATGGGCCGGTCATCTGGCAGGTATGGCTTCGGAAGAAATGGACGATGTTTATTTGATCCCGAACCGGTATCCACTTGG
CAAGTATCTGCTGGTATTCGATCCGTTGGATGGCTCTAGCAACGTTGATATCAATATTTCGGTTGGGACCATTTTCTCGA
TTCTGCGCGCACCGGTACCCGGACAGGCTGCCAGTATGGAAGATTTTTTACAGCCTGGCACCAAGCAAGTCTGTGCCGGC
TATGCCTTGTATGGTTCTTCCACCATGCTGGTGCTGACTACGGGTCATGGTGTCAACGGCTTTACACTGGATCGCGATAT
CGGTGAATTTGTGCTGACCCATCCAGGCATGAAGATTCCTGCTGACACCAGGGAATTTGCTATTAACGCATCTAATCAGC
GCTTCTGGGAGGAACCGGTGCAGCGGTACGTATCAGAATGCCTGGCAGGCAGTACTGGCCCGCGCAATCGTGATTTTAAT
ATGCGTTGGGTGGCTTCGATGGTGGCGGAAGTGCATCGTATTCTTACCCGTGGTGGCATTTTTATGTATCCGCGCGACAC
CAAGGATCCAAGCAAGCCTGGCCGATTACGCCTGATGTATGAAGCCAGCCCGATGAGTTTTATCGTTGAGCAGGCAGGTG
GTTTGTCTACAACCGGCTACGAACGCATTCTGGATATCTCGCCAGAGAATTTGCACCAGCGCGTGCCCGTGATTCTGGGA
TCAAAGAACGAAGTTGAGGTGGTGCTGGGATATCACAAAGCCTGA

Upstream 100 bases:

>100_bases
ATTTTAAAGAACGAGGATTGGTAACCATTTTTTCACACACTCGTCCATGTTGCCAAACCAGTATAATTAATGCTTTTTTA
ATTTCTCAAGAGGAATTCCG

Downstream 100 bases:

>100_bases
CAACACCTGATCGCCCGGGGGAAGCCTATATCTCGTCTTATCCCCGGTTGTGCGGCCGGGTATAATCGATCTCCGGCCCT
TTCGGGACGATCCGGGTTGG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHTGTTLTQFIIEDQRHIAGASGDFTALLNDIVTAIKTISNAVNKGALIGVMGALDTENVQGETQKKLDVITNEIMIRHN
EWAGHLAGMASEEMDDVYLIPNRYPLGKYLLVFDPLDGSSNVDINISVGTIFSILRAPVPGQAASMEDFLQPGTKQVCAG
YALYGSSTMLVLTTGHGVNGFTLDRDIGEFVLTHPGMKIPADTREFAINASNQRFWEEPVQRYVSECLAGSTGPRNRDFN
MRWVASMVAEVHRILTRGGIFMYPRDTKDPSKPGRLRLMYEASPMSFIVEQAGGLSTTGYERILDISPENLHQRVPVILG
SKNEVEVVLGYHKA

Sequences:

>Translated_334_residues
MHTGTTLTQFIIEDQRHIAGASGDFTALLNDIVTAIKTISNAVNKGALIGVMGALDTENVQGETQKKLDVITNEIMIRHN
EWAGHLAGMASEEMDDVYLIPNRYPLGKYLLVFDPLDGSSNVDINISVGTIFSILRAPVPGQAASMEDFLQPGTKQVCAG
YALYGSSTMLVLTTGHGVNGFTLDRDIGEFVLTHPGMKIPADTREFAINASNQRFWEEPVQRYVSECLAGSTGPRNRDFN
MRWVASMVAEVHRILTRGGIFMYPRDTKDPSKPGRLRLMYEASPMSFIVEQAGGLSTTGYERILDISPENLHQRVPVILG
SKNEVEVVLGYHKA
>Mature_334_residues
MHTGTTLTQFIIEDQRHIAGASGDFTALLNDIVTAIKTISNAVNKGALIGVMGALDTENVQGETQKKLDVITNEIMIRHN
EWAGHLAGMASEEMDDVYLIPNRYPLGKYLLVFDPLDGSSNVDINISVGTIFSILRAPVPGQAASMEDFLQPGTKQVCAG
YALYGSSTMLVLTTGHGVNGFTLDRDIGEFVLTHPGMKIPADTREFAINASNQRFWEEPVQRYVSECLAGSTGPRNRDFN
MRWVASMVAEVHRILTRGGIFMYPRDTKDPSKPGRLRLMYEASPMSFIVEQAGGLSTTGYERILDISPENLHQRVPVILG
SKNEVEVVLGYHKA

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=324, Percent_Identity=43.5185185185185, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI189083692, Length=321, Percent_Identity=44.2367601246106, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI16579888, Length=321, Percent_Identity=44.2367601246106, Blast_Score=252, Evalue=3e-67,
Organism=Escherichia coli, GI1790679, Length=324, Percent_Identity=45.679012345679, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17508131, Length=326, Percent_Identity=47.239263803681, Blast_Score=298, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6323409, Length=327, Percent_Identity=42.5076452599388, Blast_Score=273, Evalue=2e-74,
Organism=Drosophila melanogaster, GI45550998, Length=328, Percent_Identity=46.0365853658537, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI19921562, Length=328, Percent_Identity=46.0365853658537, Blast_Score=275, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_NITEC (Q0AGV1)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747396.1
- ProteinModelPortal:   Q0AGV1
- SMR:   Q0AGV1
- STRING:   Q0AGV1
- GeneID:   4274091
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1176
- NMPDR:   fig|335283.3.peg.941
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- PhylomeDB:   Q0AGV1
- ProtClustDB:   PRK09293
- BioCyc:   NEUT335283:NEUT_1176-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36689; Mature: 36689

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00124 FBPASE

Important sites: BINDING 209-209

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTGTTLTQFIIEDQRHIAGASGDFTALLNDIVTAIKTISNAVNKGALIGVMGALDTENV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QGETQKKLDVITNEIMIRHNEWAGHLAGMASEEMDDVYLIPNRYPLGKYLLVFDPLDGSS
CCCHHHHHHHHHHHEEEEECCHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCC
NVDINISVGTIFSILRAPVPGQAASMEDFLQPGTKQVCAGYALYGSSTMLVLTTGHGVNG
CEEEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHCCEEEECCCEEEEEEECCCCCC
FTLDRDIGEFVLTHPGMKIPADTREFAINASNQRFWEEPVQRYVSECLAGSTGPRNRDFN
EEECCCHHHHHEECCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
MRWVASMVAEVHRILTRGGIFMYPRDTKDPSKPGRLRLMYEASPMSFIVEQAGGLSTTGY
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCH
ERILDISPENLHQRVPVILGSKNEVEVVLGYHKA
HHEEECCCHHHHCCCCEEECCCCCEEEEEEECCC
>Mature Secondary Structure
MHTGTTLTQFIIEDQRHIAGASGDFTALLNDIVTAIKTISNAVNKGALIGVMGALDTENV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QGETQKKLDVITNEIMIRHNEWAGHLAGMASEEMDDVYLIPNRYPLGKYLLVFDPLDGSS
CCCHHHHHHHHHHHEEEEECCHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCC
NVDINISVGTIFSILRAPVPGQAASMEDFLQPGTKQVCAGYALYGSSTMLVLTTGHGVNG
CEEEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHCCEEEECCCEEEEEEECCCCCC
FTLDRDIGEFVLTHPGMKIPADTREFAINASNQRFWEEPVQRYVSECLAGSTGPRNRDFN
EEECCCHHHHHEECCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
MRWVASMVAEVHRILTRGGIFMYPRDTKDPSKPGRLRLMYEASPMSFIVEQAGGLSTTGY
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCH
ERILDISPENLHQRVPVILGSKNEVEVVLGYHKA
HHEEECCCHHHHCCCCEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA