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The map label for this gene is lolB [H]

Identifier: 114331136

GI number: 114331136

Start: 1177588

End: 1178274

Strand: Direct

Name: lolB [H]

Synonym: Neut_1138

Alternate gene names: 114331136

Gene position: 1177588-1178274 (Clockwise)

Preceding gene: 114331135

Following gene: 114331137

Centisome position: 44.25

GC content: 48.03

Gene sequence:

>687_bases
ATGATTTGCGTTGTGCTTTTCTGCTTTCCCGGTTTGAATGCCAGTAGAGCTGGATGTGGGAAGTGGATTCTGGGTGTGAT
TCTGATTTTAGCCGGATGTGCCGGGCCTGAAATTCACCGTGCTGAGGTAATAACGGTTGTTATTCAGCCTGTGCATGAAC
AGATTGATACTTCAGGAAAGCCCTTTGTACTTACCGGCAGGCTGGTAGTGAATGCCAAGCAGCAGAAATTTTCAGGCGGG
ATACGCTGGCGACATACCAGGCAGCGCGATGAGATTTATTTGTTTTCTCCTCTTGGACAAGTTGTTGCAGAAATTCTCCA
GGATCAGACGGGGGTTCGCCTGACAACTTCCGAGCCAGCAATTTATCAGGCGCAAAGTGCGGAATATCTTACCAACCAGG
TACTGGGCTGGGAGCTTCCTCTTGCTGGTTTGCAATTTTGGGTACGCGGAGAACATTATCCGGGCACCATTGCTGAAAAG
GATCTGAATAGGAATAATCGCACTGTAGCAATTCGGCAGGATGGATGGAATATTGCCTACCAGAGTTACTACCCGGAACA
ACCAACTGTTCCGGCTTTGCCCAGGTTATTGGAATTCAGTAGAATGGATGTAAAGATGAAGCTGATTGTTGATCAATGGG
AAAAAGAGGCAAAGGGCGTTACTGGAGTGGACAGGAAGCTGCCGTAA

Upstream 100 bases:

>100_bases
ATCCCCGGAATACTCAACAAGATATGATCCGGAATGCGCTTTAGATGACTGAAATTCGTCAGGAATTTTTTGCAGGGGGC
TGGCTGCCAGATCTCTTGAG

Downstream 100 bases:

>100_bases
CAGTTTTTAATTCTCATATAGGGTATGAACACGTTTCCAGCACCGGCTAAACTTAACCTGTTTTTGCATGTAATCGGACG
GCGAGATGACGGTTACCATT

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MICVVLFCFPGLNASRAGCGKWILGVILILAGCAGPEIHRAEVITVVIQPVHEQIDTSGKPFVLTGRLVVNAKQQKFSGG
IRWRHTRQRDEIYLFSPLGQVVAEILQDQTGVRLTTSEPAIYQAQSAEYLTNQVLGWELPLAGLQFWVRGEHYPGTIAEK
DLNRNNRTVAIRQDGWNIAYQSYYPEQPTVPALPRLLEFSRMDVKMKLIVDQWEKEAKGVTGVDRKLP

Sequences:

>Translated_228_residues
MICVVLFCFPGLNASRAGCGKWILGVILILAGCAGPEIHRAEVITVVIQPVHEQIDTSGKPFVLTGRLVVNAKQQKFSGG
IRWRHTRQRDEIYLFSPLGQVVAEILQDQTGVRLTTSEPAIYQAQSAEYLTNQVLGWELPLAGLQFWVRGEHYPGTIAEK
DLNRNNRTVAIRQDGWNIAYQSYYPEQPTVPALPRLLEFSRMDVKMKLIVDQWEKEAKGVTGVDRKLP
>Mature_228_residues
MICVVLFCFPGLNASRAGCGKWILGVILILAGCAGPEIHRAEVITVVIQPVHEQIDTSGKPFVLTGRLVVNAKQQKFSGG
IRWRHTRQRDEIYLFSPLGQVVAEILQDQTGVRLTTSEPAIYQAQSAEYLTNQVLGWELPLAGLQFWVRGEHYPGTIAEK
DLNRNNRTVAIRQDGWNIAYQSYYPEQPTVPALPRLLEFSRMDVKMKLIVDQWEKEAKGVTGVDRKLP

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 25640; Mature: 25640

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICVVLFCFPGLNASRAGCGKWILGVILILAGCAGPEIHRAEVITVVIQPVHEQIDTSGK
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEHHHHHHHCCCCC
PFVLTGRLVVNAKQQKFSGGIRWRHTRQRDEIYLFSPLGQVVAEILQDQTGVRLTTSEPA
CEEEEEEEEEECCHHHHCCCCEEEECCCCCCEEEECCHHHHHHHHHCCCCCEEEECCCCC
IYQAQSAEYLTNQVLGWELPLAGLQFWVRGEHYPGTIAEKDLNRNNRTVAIRQDGWNIAY
EEECCCHHHHHHHHCCCCCCHHHEEEEEECCCCCCCCHHHCCCCCCCEEEEEECCCEEEE
QSYYPEQPTVPALPRLLEFSRMDVKMKLIVDQWEKEAKGVTGVDRKLP
ECCCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MICVVLFCFPGLNASRAGCGKWILGVILILAGCAGPEIHRAEVITVVIQPVHEQIDTSGK
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEHHHHHHHCCCCC
PFVLTGRLVVNAKQQKFSGGIRWRHTRQRDEIYLFSPLGQVVAEILQDQTGVRLTTSEPA
CEEEEEEEEEECCHHHHCCCCEEEECCCCCCEEEECCHHHHHHHHHCCCCCEEEECCCCC
IYQAQSAEYLTNQVLGWELPLAGLQFWVRGEHYPGTIAEKDLNRNNRTVAIRQDGWNIAY
EEECCCHHHHHHHHCCCCCCHHHEEEEEECCCCCCCCHHHCCCCCCCEEEEEECCCEEEE
QSYYPEQPTVPALPRLLEFSRMDVKMKLIVDQWEKEAKGVTGVDRKLP
ECCCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]