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The map label for this gene is insF1 [C]

Identifier: 114331072

GI number: 114331072

Start: 1107904

End: 1108587

Strand: Direct

Name: insF1 [C]

Synonym: Neut_1074

Alternate gene names: 114331072

Gene position: 1107904-1108587 (Clockwise)

Preceding gene: 114331067

Following gene: 114331073

Centisome position: 41.63

GC content: 46.49

Gene sequence:

>684_bases
ATGCGGGTGAGCACCAGTGCTTATTATGACTGTTGCAAACGGCCTGTCAGATTAATTGACAGTAAAACCTGGCAACTGTG
TCAGCGTATGAAAACACTGTTCATACAATCACGGGCAAGTTTGGGAAATCGGCAAATGGTTGCACAACTGCGCAAAGAAG
GCCTCATGGTTGGACGTTATAAAGTTAGCAAGCTTATGAAAAAGCTGGGATTAACAGTCAGAAACAGGCAGCGTTATGTA
GTAACAACCAGCAAACATAATCAGCCAGTGGCTGACAACAAGTTGAACAGAGATTTCTCTCCCAAACAGCCTAACCTGGT
GTGGACAACCGGCATCACTTACATCCGGACAGCACAAGGATGGATATATTTGGCGGTTGTACTGGATCTCTACTCACGGC
GCATTGTGGGTTGGCATATGGAGTATTACATGACGACTGCTCTGGTAAATCGTGCACTGATGATGGCAATCAACCTGAGA
CAACCACCAAAAAATCTGTTGCATCACTCCGACAGAGGTAGCCAGTATGCTTCACACGACTACCAAACGCTACTGACTCA
GCACAACATGCAATGTTCGATGAGCCGCAAAGGAAACTGTTGGGATACTCAGTTTAATATGGTATGGAATGCCCGGCTTG
ATCTGACCCGTGTTGGGATTGGCGAAGTAGTGCCTTTGCGTTGA

Upstream 100 bases:

>100_bases
GGATGAAGGCGAGCGCCTTCTTTGCGAAAGAGATGAAGTGAAATATACCTTCATCCGGTTCCAGCAACCACATTACCCTG
TTACTGCTTTATGTCGGGTA

Downstream 100 bases:

>100_bases
CCTGTCGATCTGGCCCAGGCATTCCCTGAGCGTTGCCGGGCCCAATACATGTGGCCTAATAGGAGCCTTGAATTGCACCG
TGAGTGTCCTGTCCGGTAAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRVSTSAYYDCCKRPVRLIDSKTWQLCQRMKTLFIQSRASLGNRQMVAQLRKEGLMVGRYKVSKLMKKLGLTVRNRQRYV
VTTSKHNQPVADNKLNRDFSPKQPNLVWTTGITYIRTAQGWIYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLR
QPPKNLLHHSDRGSQYASHDYQTLLTQHNMQCSMSRKGNCWDTQFNMVWNARLDLTRVGIGEVVPLR

Sequences:

>Translated_227_residues
MRVSTSAYYDCCKRPVRLIDSKTWQLCQRMKTLFIQSRASLGNRQMVAQLRKEGLMVGRYKVSKLMKKLGLTVRNRQRYV
VTTSKHNQPVADNKLNRDFSPKQPNLVWTTGITYIRTAQGWIYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLR
QPPKNLLHHSDRGSQYASHDYQTLLTQHNMQCSMSRKGNCWDTQFNMVWNARLDLTRVGIGEVVPLR
>Mature_227_residues
MRVSTSAYYDCCKRPVRLIDSKTWQLCQRMKTLFIQSRASLGNRQMVAQLRKEGLMVGRYKVSKLMKKLGLTVRNRQRYV
VTTSKHNQPVADNKLNRDFSPKQPNLVWTTGITYIRTAQGWIYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLR
QPPKNLLHHSDRGSQYASHDYQTLLTQHNMQCSMSRKGNCWDTQFNMVWNARLDLTRVGIGEVVPLR

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=211, Percent_Identity=34.1232227488152, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1788405, Length=205, Percent_Identity=38.0487804878049, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787263, Length=205, Percent_Identity=38.0487804878049, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786753, Length=205, Percent_Identity=38.0487804878049, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786570, Length=205, Percent_Identity=38.0487804878049, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786490, Length=205, Percent_Identity=38.0487804878049, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789981, Length=202, Percent_Identity=29.2079207920792, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 26547; Mature: 26547

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSTSAYYDCCKRPVRLIDSKTWQLCQRMKTLFIQSRASLGNRQMVAQLRKEGLMVGRY
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECHH
KVSKLMKKLGLTVRNRQRYVVTTSKHNQPVADNKLNRDFSPKQPNLVWTTGITYIRTAQG
HHHHHHHHHCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCC
WIYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLRQPPKNLLHHSDRGSQYASHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHH
YQTLLTQHNMQCSMSRKGNCWDTQFNMVWNARLDLTRVGIGEVVPLR
HHHHHHHCCCEEECCCCCCCCCCEEEEEEECEEEEEECCCCCEECCC
>Mature Secondary Structure
MRVSTSAYYDCCKRPVRLIDSKTWQLCQRMKTLFIQSRASLGNRQMVAQLRKEGLMVGRY
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECHH
KVSKLMKKLGLTVRNRQRYVVTTSKHNQPVADNKLNRDFSPKQPNLVWTTGITYIRTAQG
HHHHHHHHHCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCC
WIYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLRQPPKNLLHHSDRGSQYASHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHH
YQTLLTQHNMQCSMSRKGNCWDTQFNMVWNARLDLTRVGIGEVVPLR
HHHHHHHCCCEEECCCCCCCCCCEEEEEEECEEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]