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The map label for this gene is nuoA [H]

Identifier: 114330925

GI number: 114330925

Start: 948717

End: 949073

Strand: Direct

Name: nuoA [H]

Synonym: Neut_0922

Alternate gene names: 114330925

Gene position: 948717-949073 (Clockwise)

Preceding gene: 114330924

Following gene: 114330926

Centisome position: 35.65

GC content: 41.46

Gene sequence:

>357_bases
ATGCTTGGGAATTATTTCCCTATTTTATTGTTTATTTTGGTGGGTCTGCTAGTTGGCACATTATGTTTGGTGGCGGGTTG
GTTGCTTGCGCCAAACAAGCCGGATGCCGAAAAATTGTCGACCTATGAGTGTGGGTTTGGTGCATTTGAGGATGCGCGCA
TGAAATTTGATGTGCGCTACTATTTAATTGCAATCCTGTTTATTTTATTTGATTTAGAAATAGCTTTCTTATTTCCTTGG
GCAGTAGCGCTGAAAGAAGTGGGATTGTTTGGTTTTATTGCGATGCTAGTATTTCTTGGATTGCTCGTCGTCGGCTTTAT
TTACGAGTGGGCTAAGGGTGCTTTGGAATGGGATTAA

Upstream 100 bases:

>100_bases
TCTCGCCGTCGGCACCAGGCGAGCATATTTACAAATAGGAATTAAGCGAAAATCAATTTTATTTCCATGGTTTAGTAAGG
AATTGGAGATGCTGGATACC

Downstream 100 bases:

>100_bases
ATAATGGGTATTGAGGGTGCATTAGACAAAGGATTTGTTACCACAAACCTTGATTCCTTGATTAATTGGGGACGCACAGG
ATCAATGTGGCCTATGACAT

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLGNYFPILLFILVGLLVGTLCLVAGWLLAPNKPDAEKLSTYECGFGAFEDARMKFDVRYYLIAILFILFDLEIAFLFPW
AVALKEVGLFGFIAMLVFLGLLVVGFIYEWAKGALEWD

Sequences:

>Translated_118_residues
MLGNYFPILLFILVGLLVGTLCLVAGWLLAPNKPDAEKLSTYECGFGAFEDARMKFDVRYYLIAILFILFDLEIAFLFPW
AVALKEVGLFGFIAMLVFLGLLVVGFIYEWAKGALEWD
>Mature_118_residues
MLGNYFPILLFILVGLLVGTLCLVAGWLLAPNKPDAEKLSTYECGFGAFEDARMKFDVRYYLIAILFILFDLEIAFLFPW
AVALKEVGLFGFIAMLVFLGLLVVGFIYEWAKGALEWD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=118, Percent_Identity=29.6610169491525, Blast_Score=76, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13311; Mature: 13311

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGNYFPILLFILVGLLVGTLCLVAGWLLAPNKPDAEKLSTYECGFGAFEDARMKFDVRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
YLIAILFILFDLEIAFLFPWAVALKEVGLFGFIAMLVFLGLLVVGFIYEWAKGALEWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLGNYFPILLFILVGLLVGTLCLVAGWLLAPNKPDAEKLSTYECGFGAFEDARMKFDVRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
YLIAILFILFDLEIAFLFPWAVALKEVGLFGFIAMLVFLGLLVVGFIYEWAKGALEWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]