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The map label for this gene is dsbD [H]

Identifier: 114330852

GI number: 114330852

Start: 865060

End: 867003

Strand: Reverse

Name: dsbD [H]

Synonym: Neut_0846

Alternate gene names: 114330852

Gene position: 867003-865060 (Counterclockwise)

Preceding gene: 114330853

Following gene: 114330851

Centisome position: 32.58

GC content: 50.1

Gene sequence:

>1944_bases
ATGCGCTGGATAAAATTCATTTTGATTTTACTGTCACTATGCTTGATCAGTACGCACACCATGGCCGAAGAAAGCCGGTC
CGGGGGGTTGATGAGTATTCTGCAACGATTGGGGATGAGTATCGATCAGACCGAGCAGGAATTGTTGCCACCGGATGAGG
CCTTCAAGCTGTCCCTCGAAGTACGGGATGATCACACACTGATTGCCCGCCTGACACCAGCCAGGGATTACTATCTTTAT
CGTGACAAGATTGCTTTTGAATCAAAGAGTGAAGGGATTCACATTGAGCAAGTCACCCTGCCATCAGGGAAAATGAAGAA
TGACCAGCTCTTTGGCAACACTGAAGTGTACTACCAGCCATTGGAAGCTGTTATCACACTGCGCCGCGAATCATCTGCTC
CGGAGCAGCTATCCCTCTCTGCTACCTACCAGGGTTGTAACGAACCAATCGGTGTGTGCTATGCGCCGATCAACAAGGAA
AATGAACTACTGCTGCCCGCCCTGAAGGCCATAGTGAACACAGCCGCCGGCGCTATCAGCAACAATGTGCAAGCAGCCAA
TGCTGACTCTACTGCCGAACTGTTTCAATCACCTGGCAATACTGCCCCATTATTTGAAACAGAATCCTATAAAATAGAAC
GCCTGTTCGCCAGTGGCAATTTCTGGCTGATTCTGAGTGGCTTTTTTGGCATTGGCGTGCTACTCGCTTTCACGCCCTGC
ATATTCCCCATGTTGCCAATTCTGTCCGGCATCATCGCCAGCAAAGGACAGCAAATGTCAAAAACACACGGCTTCATACT
GGCATTGGCCTATGTGCTGGGGATGTCGATCACTTATGCCGCAGCCGGTGCTGCCGCAGGCTTATCCGGGGCCATGTTAT
CCGCCTCACTACAAAATGCCTGGGTACTGGGAACATTCGCACTGATCTTTACTGCACTGGCACTCTCCATGTTTGGTTTC
TACGAACTGCAAATGCCCGCTTTCATACAAAACAAGTTGATAGAAGAAGCCAATCATTTCAAGGGTGGCCAACTGGCTGG
CGTGTTTGGAATGGGCGCACTGTCCGCACTGATCGTCAGCCCCTGTGTTGCCGCTCCGCTCGCTGGTGCATTGATCTATA
TCAGCCAGACTCGCGATGTCGTGCTGGGTGGATCCGCCCTGTTTGTCATGGCATTGGGAATGGGTGTTCCCCTACTGTTG
CTCGGTGTTTCTGCTGGTGCACTATTACCTAAAGCTGGTGCGTGGATGAAATCCATTCAGCAATTTTTTGGTGTCCTGCT
GCTGGCTGTGGCCATCTGGCTGATCTCTCCCGTAATTACAGAAGTCGTCCACATGCTGCTCTGGGCAGCGTTGCTGATTA
TTTCAGCCATCTATCTACATGCGCTTGATCCGCTACCTCATCAGGCTTCTGGCTTCAGTAAATTTCTCAAGGGGATCGGC
GTTATTGCATTGCTGACCGGTGTTGCATTACTCATCGGCGTACTTTCCGGAAGCCGGGATATCCTGCAACCCTTGTCAAA
ATTCAACCTGACTGCATCCACCTCTTCCGCGCAGCTTGCTGAATCGCCGGCTGGCATGAACGCTCCCCTGCCATTCAAGC
AAATAAAAACAGCTGCAGAACTGGACGAACTCATCCGGCAATCACGGGGACATTACGTCATGATCGACTTTTATGCCGAC
TGGTGTATTTCCTGCAAGGAAATGGAACGCTTCACCTTTACCGATCCACAGGTCCAGGCACGTCTAAAAAATGTCGAGCT
GGTTCAGATCAACGTAACTGAAGGAACACCGGATGACGCCGAACTACTCAAACGTTTCAAACTCTTCGGCCCGCCTGGAA
TTCTGTTTTTTGATAAACAGGGAGTTGAGATTCCTGACATCAAGATTATTGGCTATCTCGACAAAAAAGACTTTGTTACC
GTACTGGATGCAATACTGCTCTGA

Upstream 100 bases:

>100_bases
CCCTGAAGTTATTGCTGTCCCTCTCGATAACGGGTTGCCTGCTTACTTGCAGTGGGTCGCTAATGAAACAACCGAAACAG
ATGTTTAACCAGGATAACCA

Downstream 100 bases:

>100_bases
CAACCAGGCAGCAGGCAGCAACCATCCACATTTGCACTATTTTGCAGATATATAGCAGTACACGCTGTGCCTTGAGTGCG
CCAGTACGGTAAATACCAAA

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MRWIKFILILLSLCLISTHTMAEESRSGGLMSILQRLGMSIDQTEQELLPPDEAFKLSLEVRDDHTLIARLTPARDYYLY
RDKIAFESKSEGIHIEQVTLPSGKMKNDQLFGNTEVYYQPLEAVITLRRESSAPEQLSLSATYQGCNEPIGVCYAPINKE
NELLLPALKAIVNTAAGAISNNVQAANADSTAELFQSPGNTAPLFETESYKIERLFASGNFWLILSGFFGIGVLLAFTPC
IFPMLPILSGIIASKGQQMSKTHGFILALAYVLGMSITYAAAGAAAGLSGAMLSASLQNAWVLGTFALIFTALALSMFGF
YELQMPAFIQNKLIEEANHFKGGQLAGVFGMGALSALIVSPCVAAPLAGALIYISQTRDVVLGGSALFVMALGMGVPLLL
LGVSAGALLPKAGAWMKSIQQFFGVLLLAVAIWLISPVITEVVHMLLWAALLIISAIYLHALDPLPHQASGFSKFLKGIG
VIALLTGVALLIGVLSGSRDILQPLSKFNLTASTSSAQLAESPAGMNAPLPFKQIKTAAELDELIRQSRGHYVMIDFYAD
WCISCKEMERFTFTDPQVQARLKNVELVQINVTEGTPDDAELLKRFKLFGPPGILFFDKQGVEIPDIKIIGYLDKKDFVT
VLDAILL

Sequences:

>Translated_647_residues
MRWIKFILILLSLCLISTHTMAEESRSGGLMSILQRLGMSIDQTEQELLPPDEAFKLSLEVRDDHTLIARLTPARDYYLY
RDKIAFESKSEGIHIEQVTLPSGKMKNDQLFGNTEVYYQPLEAVITLRRESSAPEQLSLSATYQGCNEPIGVCYAPINKE
NELLLPALKAIVNTAAGAISNNVQAANADSTAELFQSPGNTAPLFETESYKIERLFASGNFWLILSGFFGIGVLLAFTPC
IFPMLPILSGIIASKGQQMSKTHGFILALAYVLGMSITYAAAGAAAGLSGAMLSASLQNAWVLGTFALIFTALALSMFGF
YELQMPAFIQNKLIEEANHFKGGQLAGVFGMGALSALIVSPCVAAPLAGALIYISQTRDVVLGGSALFVMALGMGVPLLL
LGVSAGALLPKAGAWMKSIQQFFGVLLLAVAIWLISPVITEVVHMLLWAALLIISAIYLHALDPLPHQASGFSKFLKGIG
VIALLTGVALLIGVLSGSRDILQPLSKFNLTASTSSAQLAESPAGMNAPLPFKQIKTAAELDELIRQSRGHYVMIDFYAD
WCISCKEMERFTFTDPQVQARLKNVELVQINVTEGTPDDAELLKRFKLFGPPGILFFDKQGVEIPDIKIIGYLDKKDFVT
VLDAILL
>Mature_647_residues
MRWIKFILILLSLCLISTHTMAEESRSGGLMSILQRLGMSIDQTEQELLPPDEAFKLSLEVRDDHTLIARLTPARDYYLY
RDKIAFESKSEGIHIEQVTLPSGKMKNDQLFGNTEVYYQPLEAVITLRRESSAPEQLSLSATYQGCNEPIGVCYAPINKE
NELLLPALKAIVNTAAGAISNNVQAANADSTAELFQSPGNTAPLFETESYKIERLFASGNFWLILSGFFGIGVLLAFTPC
IFPMLPILSGIIASKGQQMSKTHGFILALAYVLGMSITYAAAGAAAGLSGAMLSASLQNAWVLGTFALIFTALALSMFGF
YELQMPAFIQNKLIEEANHFKGGQLAGVFGMGALSALIVSPCVAAPLAGALIYISQTRDVVLGGSALFVMALGMGVPLLL
LGVSAGALLPKAGAWMKSIQQFFGVLLLAVAIWLISPVITEVVHMLLWAALLIISAIYLHALDPLPHQASGFSKFLKGIG
VIALLTGVALLIGVLSGSRDILQPLSKFNLTASTSSAQLAESPAGMNAPLPFKQIKTAAELDELIRQSRGHYVMIDFYAD
WCISCKEMERFTFTDPQVQARLKNVELVQINVTEGTPDDAELLKRFKLFGPPGILFFDKQGVEIPDIKIIGYLDKKDFVT
VLDAILL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=594, Percent_Identity=34.8484848484849, Blast_Score=342, Evalue=4e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 70038; Mature: 70038

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWIKFILILLSLCLISTHTMAEESRSGGLMSILQRLGMSIDQTEQELLPPDEAFKLSLE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHCCCCCCCEEEEEE
VRDDHTLIARLTPARDYYLYRDKIAFESKSEGIHIEQVTLPSGKMKNDQLFGNTEVYYQP
ECCCCEEEEEECCCCCEEEEECCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHH
LEAVITLRRESSAPEQLSLSATYQGCNEPIGVCYAPINKENELLLPALKAIVNTAAGAIS
HHHHHHHHHCCCCCCCEEEEHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
NNVQAANADSTAELFQSPGNTAPLFETESYKIERLFASGNFWLILSGFFGIGVLLAFTPC
CCCCCCCCCHHHHHHHCCCCCCCCEECCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHH
IFPMLPILSGIIASKGQQMSKTHGFILALAYVLGMSITYAAAGAAAGLSGAMLSASLQNA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCH
WVLGTFALIFTALALSMFGFYELQMPAFIQNKLIEEANHFKGGQLAGVFGMGALSALIVS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
PCVAAPLAGALIYISQTRDVVLGGSALFVMALGMGVPLLLLGVSAGALLPKAGAWMKSIQ
HHHHHHHHCEEEEEECCCCEEECCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHH
QFFGVLLLAVAIWLISPVITEVVHMLLWAALLIISAIYLHALDPLPHQASGFSKFLKGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VIALLTGVALLIGVLSGSRDILQPLSKFNLTASTSSAQLAESPAGMNAPLPFKQIKTAAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHH
LDELIRQSRGHYVMIDFYADWCISCKEMERFTFTDPQVQARLKNVELVQINVTEGTPDDA
HHHHHHHCCCCEEEEEECCCHHHCHHHHCCCCCCCHHHHHHHCCEEEEEEEECCCCCCHH
ELLKRFKLFGPPGILFFDKQGVEIPDIKIIGYLDKKDFVTVLDAILL
HHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure
MRWIKFILILLSLCLISTHTMAEESRSGGLMSILQRLGMSIDQTEQELLPPDEAFKLSLE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHCCCCCCCEEEEEE
VRDDHTLIARLTPARDYYLYRDKIAFESKSEGIHIEQVTLPSGKMKNDQLFGNTEVYYQP
ECCCCEEEEEECCCCCEEEEECCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHH
LEAVITLRRESSAPEQLSLSATYQGCNEPIGVCYAPINKENELLLPALKAIVNTAAGAIS
HHHHHHHHHCCCCCCCEEEEHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
NNVQAANADSTAELFQSPGNTAPLFETESYKIERLFASGNFWLILSGFFGIGVLLAFTPC
CCCCCCCCCHHHHHHHCCCCCCCCEECCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHH
IFPMLPILSGIIASKGQQMSKTHGFILALAYVLGMSITYAAAGAAAGLSGAMLSASLQNA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCH
WVLGTFALIFTALALSMFGFYELQMPAFIQNKLIEEANHFKGGQLAGVFGMGALSALIVS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
PCVAAPLAGALIYISQTRDVVLGGSALFVMALGMGVPLLLLGVSAGALLPKAGAWMKSIQ
HHHHHHHHCEEEEEECCCCEEECCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHH
QFFGVLLLAVAIWLISPVITEVVHMLLWAALLIISAIYLHALDPLPHQASGFSKFLKGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VIALLTGVALLIGVLSGSRDILQPLSKFNLTASTSSAQLAESPAGMNAPLPFKQIKTAAE
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHH
LDELIRQSRGHYVMIDFYADWCISCKEMERFTFTDPQVQARLKNVELVQINVTEGTPDDA
HHHHHHHCCCCEEEEEECCCHHHCHHHHCCCCCCCHHHHHHHCCEEEEEEEECCCCCCHH
ELLKRFKLFGPPGILFFDKQGVEIPDIKIIGYLDKKDFVTVLDAILL
HHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]