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The map label for this gene is trxB [H]

Identifier: 114330804

GI number: 114330804

Start: 811386

End: 812339

Strand: Direct

Name: trxB [H]

Synonym: Neut_0792

Alternate gene names: 114330804

Gene position: 811386-812339 (Clockwise)

Preceding gene: 114330803

Following gene: 114330805

Centisome position: 30.49

GC content: 50.0

Gene sequence:

>954_bases
ATGACAACAACCAGACATTGCAAATTACTCATTCTCGGATCCGGCCCAGCCGGCTATACAGCAGCCATTTATGCTGCACG
GGCGAATCTCAATCCGGTGCTGATTACCGGGATGGCGCAAGGTGGGCAACTCACGACGACGACGGATGTGGATAACTGGC
CGGCGGATGTTGCCGGGGTGCAGGGTCCAGAGTTGATGGAGCGCTTTCTGAAGCATGCTGAGCGTTTTCAGACTGAAATC
ATATTTGATCATATCCATACCGCCAAATTGTCAGGAAAGTCGTTTGAACTGACAGGCGACCAAGGAACCTACACCTGTGA
TGCACTGATTATTGCGACAGGCGCTTCGGCGAAATATCTCGGGCTGCCTTCAGAGGAAGCTTTTATGGGGAAAGGGGTTT
CAGCCTGTGCAACTTGTGATGGGTTTTTCTATAAAAATCAGGATGTGGCTGTCATTGGGGGAGGGAATACCGCAGTAGAG
GAAGCGTTGTATCTCTCTAATATTGCTCGTAAGGTAACTGTGGTACATCGTCGTGACAAGTTCCGTTCAGAAAAAATTCT
GATCGACAAATTGATGGAAAAGGTACAAAGCGGCAAGATTGAGCTAGCGCTTGATCACGTTCTGGAAGAGGTGAAGGGTG
ATGACAGTGGCGTTACCGGAGTTCGCATTCGTCATGTCCGGGACGATACGGCACGTGATCTTGATTTGCAGGGTGTGTTC
ATCGCTATCGGGCATCATCCCAATACTGATCTATTCCAGGGACAGCTGGAAATGAAAAATGGCTACATTATTACGCAAGG
TGGGAACGAGGGTAATGCAACAGCGACCAGTATCCCGGGTGTATTCGCGGCTGGTGACGTGCAGGATCATATTTATCGCC
AGGCGGTTACCAGTGCCGGCAGTGGCTGTATGGCTGCTCTGGATGCGGAAAGATATCTTGAAAAATCCAGCTGA

Upstream 100 bases:

>100_bases
TGCCAGACAAGCTACCGCAAGCTCTGACAAGTGTGGCGGGCTGGGTGGAACGCAATCTTTAACCTGTAATTAAAAATTAT
TCAAATACCTCTTATTCAAT

Downstream 100 bases:

>100_bases
GTGCCATGAATTTTCTGTCCGCATATTTACGTATAGAGAAGGATAACCCGTCATCCAGTCAGGAGACTATCCATGATGCT
GCTGCCTTGTTCCGCGAGGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTTTRHCKLLILGSGPAGYTAAIYAARANLNPVLITGMAQGGQLTTTTDVDNWPADVAGVQGPELMERFLKHAERFQTEI
IFDHIHTAKLSGKSFELTGDQGTYTCDALIIATGASAKYLGLPSEEAFMGKGVSACATCDGFFYKNQDVAVIGGGNTAVE
EALYLSNIARKVTVVHRRDKFRSEKILIDKLMEKVQSGKIELALDHVLEEVKGDDSGVTGVRIRHVRDDTARDLDLQGVF
IAIGHHPNTDLFQGQLEMKNGYIITQGGNEGNATATSIPGVFAAGDVQDHIYRQAVTSAGSGCMAALDAERYLEKSS

Sequences:

>Translated_317_residues
MTTTRHCKLLILGSGPAGYTAAIYAARANLNPVLITGMAQGGQLTTTTDVDNWPADVAGVQGPELMERFLKHAERFQTEI
IFDHIHTAKLSGKSFELTGDQGTYTCDALIIATGASAKYLGLPSEEAFMGKGVSACATCDGFFYKNQDVAVIGGGNTAVE
EALYLSNIARKVTVVHRRDKFRSEKILIDKLMEKVQSGKIELALDHVLEEVKGDDSGVTGVRIRHVRDDTARDLDLQGVF
IAIGHHPNTDLFQGQLEMKNGYIITQGGNEGNATATSIPGVFAAGDVQDHIYRQAVTSAGSGCMAALDAERYLEKSS
>Mature_316_residues
TTTRHCKLLILGSGPAGYTAAIYAARANLNPVLITGMAQGGQLTTTTDVDNWPADVAGVQGPELMERFLKHAERFQTEII
FDHIHTAKLSGKSFELTGDQGTYTCDALIIATGASAKYLGLPSEEAFMGKGVSACATCDGFFYKNQDVAVIGGGNTAVEE
ALYLSNIARKVTVVHRRDKFRSEKILIDKLMEKVQSGKIELALDHVLEEVKGDDSGVTGVRIRHVRDDTARDLDLQGVFI
AIGHHPNTDLFQGQLEMKNGYIITQGGNEGNATATSIPGVFAAGDVQDHIYRQAVTSAGSGCMAALDAERYLEKSS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=71.1111111111111, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=34.2948717948718, Blast_Score=142, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=47.8125, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=47.5, Blast_Score=272, Evalue=4e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34040; Mature: 33909

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTRHCKLLILGSGPAGYTAAIYAARANLNPVLITGMAQGGQLTTTTDVDNWPADVAGV
CCCCCEEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMERFLKHAERFQTEIIFDHIHTAKLSGKSFELTGDQGTYTCDALIIATGASAKYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCEEEEEEEEEECCCCEEE
GLPSEEAFMGKGVSACATCDGFFYKNQDVAVIGGGNTAVEEALYLSNIARKVTVVHRRDK
CCCCCHHHHCCCCCHHEECCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHH
FRSEKILIDKLMEKVQSGKIELALDHVLEEVKGDDSGVTGVRIRHVRDDTARDLDLQGVF
HCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCEEE
IAIGHHPNTDLFQGQLEMKNGYIITQGGNEGNATATSIPGVFAAGDVQDHIYRQAVTSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCEEECCCCEEEECCHHHHHHHHHHHCCC
SGCMAALDAERYLEKSS
CCCEEECCHHHHHHCCC
>Mature Secondary Structure 
TTTRHCKLLILGSGPAGYTAAIYAARANLNPVLITGMAQGGQLTTTTDVDNWPADVAGV
CCCCEEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMERFLKHAERFQTEIIFDHIHTAKLSGKSFELTGDQGTYTCDALIIATGASAKYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCEEEEEEEEEECCCCEEE
GLPSEEAFMGKGVSACATCDGFFYKNQDVAVIGGGNTAVEEALYLSNIARKVTVVHRRDK
CCCCCHHHHCCCCCHHEECCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHH
FRSEKILIDKLMEKVQSGKIELALDHVLEEVKGDDSGVTGVRIRHVRDDTARDLDLQGVF
HCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCEEE
IAIGHHPNTDLFQGQLEMKNGYIITQGGNEGNATATSIPGVFAAGDVQDHIYRQAVTSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCEEECCCCEEEECCHHHHHHHHHHHCCC
SGCMAALDAERYLEKSS
CCCEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]